CA2825980C - Bifidobacterium bifidum strains for application in gastrointestinal diseases - Google Patents

Bifidobacterium bifidum strains for application in gastrointestinal diseases Download PDF

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Publication number
CA2825980C
CA2825980C CA2825980A CA2825980A CA2825980C CA 2825980 C CA2825980 C CA 2825980C CA 2825980 A CA2825980 A CA 2825980A CA 2825980 A CA2825980 A CA 2825980A CA 2825980 C CA2825980 C CA 2825980C
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strain
cfu
variant
mutant
bifidobacterium bifidum
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CA2825980A
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English (en)
French (fr)
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CA2825980A1 (en
Inventor
Simone GUGLIELMETTI
Diego Mora
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Synformulas GmbH
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Synformulas GmbH
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Publication of CA2825980A1 publication Critical patent/CA2825980A1/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2825980A 2011-01-31 2012-01-27 Bifidobacterium bifidum strains for application in gastrointestinal diseases Active CA2825980C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11000744.0A EP2481299B1 (en) 2011-01-31 2011-01-31 Bifidobacterium bifidum strains for application in gastrointestinal diseases
EP11000744.0 2011-01-31
PCT/EP2012/051369 WO2012104226A1 (en) 2011-01-31 2012-01-27 Bifidobacterium bifidum strains for application in gastrointestinal diseases

Publications (2)

Publication Number Publication Date
CA2825980A1 CA2825980A1 (en) 2012-08-09
CA2825980C true CA2825980C (en) 2017-10-24

Family

ID=43901563

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2825980A Active CA2825980C (en) 2011-01-31 2012-01-27 Bifidobacterium bifidum strains for application in gastrointestinal diseases

Country Status (15)

Country Link
US (1) US9408879B2 (enExample)
EP (1) EP2481299B1 (enExample)
JP (1) JP5956467B2 (enExample)
CN (1) CN103476273A (enExample)
AU (1) AU2012213576B2 (enExample)
BR (1) BR112013019258B1 (enExample)
CA (1) CA2825980C (enExample)
DK (1) DK2481299T3 (enExample)
ES (1) ES2610908T3 (enExample)
HR (1) HRP20161792T1 (enExample)
HU (1) HUE033189T2 (enExample)
PL (1) PL2481299T3 (enExample)
PT (1) PT2481299T (enExample)
RU (1) RU2603285C2 (enExample)
WO (1) WO2012104226A1 (enExample)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
CN103266076B (zh) * 2013-06-04 2014-10-29 神舟太空产品高科技成果推广中心集团有限公司 太空诱变高效两歧双歧杆菌、其应用及其胶囊制剂的制备方法
CN104546945A (zh) * 2014-09-30 2015-04-29 深圳华大基因科技有限公司 两歧双歧杆菌在治疗或预防类风湿性关节炎或其相关疾病中的用途
PT3065748T (pt) 2014-12-23 2018-02-28 4D Pharma Res Ltd Uma estirpe de bacteroides thetaiotaomicron e o seu uso na redução da inflamação
BR112017013274A2 (pt) 2014-12-23 2018-02-06 4D Pharma Research Limited polipeptídeo e imunomodulação
JP2018507872A (ja) * 2015-03-09 2018-03-22 バイオイミュナイザー・ソチエタ・ア・ガランツィア・リミタータBioimmunizer SAGL ビフィズス菌およびプロバイオティクスから単離された細胞壁をともなう抗酸化剤の組み合わせを含むアンチエイジング組成物
SMT201900588T1 (it) 2015-06-15 2019-11-13 4D Pharma Res Limited Blautia stercoris e wexlerae per uso nel trattamento di malattie infiammatorie ed autoimmuni
PL3307288T3 (pl) 2015-06-15 2019-12-31 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
PT3360559T (pt) 2015-06-15 2020-01-06 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
JP6637725B2 (ja) * 2015-10-28 2020-01-29 ビオフェルミン製薬株式会社 ウイルス感染症の予防及び/又は治療剤
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
HUE036362T2 (hu) 2015-11-20 2018-07-30 4D Pharma Res Ltd Baktériumtörzseket tartalmazó készítmények
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
PL3313423T3 (pl) 2016-03-04 2019-09-30 4D Pharma Plc Kompozycje zawierające szczepy bakteryjne blautia do leczenia nadwrażliwości trzewnej
CA3020389A1 (en) * 2016-04-14 2017-10-19 Dupont Nutrition Biosciences Aps Bifidobacteria for increasing lean body mass
TWI802545B (zh) 2016-07-13 2023-05-21 英商4D製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
CN106579414A (zh) * 2016-12-26 2017-04-26 北京康比特体育科技股份有限公司 一种缓解运动性腹泻的组合物
CN106834187B (zh) * 2017-03-06 2020-08-25 江南大学 一种两歧双歧杆菌及其用途
WO2018165563A1 (en) * 2017-03-09 2018-09-13 The Clorox Company Probiotic capsule and methods of preparing the same
JP2018177703A (ja) * 2017-04-14 2018-11-15 株式会社明治 Toll様受容体2活性化用組成物
JP7212945B2 (ja) 2017-05-22 2023-01-26 フォーディー ファーマ リサーチ リミテッド 細菌株を含む組成物
MA41708A (fr) 2017-05-24 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
HUE059249T2 (hu) 2017-06-14 2022-11-28 4D Pharma Res Limited Baktériumtörzseket tartalmazó készítmények
PT3638271T (pt) 2017-06-14 2021-01-05 4D Pharma Res Ltd Composições contendo estirpes bacterianas
AU2018285445B2 (en) 2017-06-14 2020-03-26 Cj Bioscience, Inc. Compositions comprising bacterial strains
KR102760825B1 (ko) * 2018-01-29 2025-02-03 프리시젼바이오틱스 그룹 리미티드 과민성 대장 증후군의 예방 및 치료를 위한 조합 생성물
KR102023700B1 (ko) * 2018-01-31 2019-09-20 주식회사 비피도 비피도박테리움을 함유한 류마티스관절염 개선용, 치료용 또는 예방용 조성물
AU2019289987A1 (en) * 2018-06-22 2020-12-24 Synformulas Gmbh Non-viable Bifidobacterium bifidum bacteria and uses thereof
BR112021007249A2 (pt) * 2019-01-16 2021-08-10 N.V. Nutricia composições nutricionais
IT201900011193A1 (it) * 2019-07-08 2021-01-08 Sofar Spa Ceppo di batteri Bifidobacterium bifidum, sue composizioni e relativi usi
WO2021044376A1 (en) * 2019-09-05 2021-03-11 White Dog Labs, Inc. Mixotrophic probiotic compositions and uses thereof in the treatment of bloating
IT201900016811A1 (it) * 2019-09-20 2021-03-20 Sofar Spa Ceppi batterici, loro composizioni e loro uso per il trattamento di disturbi gastrointestinali
CN118924795A (zh) * 2019-11-29 2024-11-12 内蒙古伊利实业集团股份有限公司 乳双歧杆菌bl-99提升肠道细菌感染抗性和肠道免疫力的应用
CN111110704B (zh) * 2020-02-14 2023-03-28 上海城建职业学院 一种益生菌菌剂、滴剂及其制备方法和应用
CN111743998A (zh) * 2020-06-04 2020-10-09 中通美雅生命健康(深圳)有限公司 用于辅助治疗肠炎组合物及其制备方法
RU2735717C1 (ru) * 2020-06-15 2020-11-06 Общество с ограниченной ответственностью "АВАН" Штамм Bifidobacterium bifidum, используемый в качестве пробиотика
JP2023542547A (ja) * 2020-09-23 2023-10-10 ピービーエルバイオラブ 新規乳酸菌およびその用途
CN113943682B (zh) * 2020-11-12 2023-07-04 江南大学 缓解便秘的长双歧杆菌长亚种及其制备的发酵食品与益生菌制剂
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
US20240000808A1 (en) * 2020-11-16 2024-01-04 Orcosa Inc. Improved use of cannabinoids in the treatment of alzheimer's disease
CN112980734B (zh) * 2021-03-24 2022-07-22 江南大学 一株缓解便秘并调节肠道菌群紊乱的两歧双歧杆菌及其应用
CN113025526B (zh) * 2021-03-24 2022-09-27 江南大学 一株减少结肠病理损伤且具有缓解便秘作用的两歧双歧杆菌
CN113234619B (zh) * 2021-04-10 2022-07-05 江南大学 一株两歧双歧杆菌及其在缓解肠道损伤中的应用
CN118291322A (zh) * 2022-07-13 2024-07-05 四川大学 一株婴幼儿肠道来源的两歧双歧杆菌
CN116286439A (zh) * 2022-07-13 2023-06-23 四川大学 一株婴幼儿肠道来源的两歧双歧杆菌及应用
CN115838662A (zh) * 2022-11-02 2023-03-24 江南大学 一株具有缓解克罗恩病潜力的两歧双歧杆菌
WO2024193633A1 (zh) * 2023-03-21 2024-09-26 四川厌氧生物科技有限责任公司 一种益生菌及其应用
CN118044616A (zh) * 2023-09-05 2024-05-17 厦门大学 一种合生元及其用途
WO2025059424A1 (en) * 2023-09-15 2025-03-20 Biohm Health Inc. Pro-biotic compositions and methods for treatment of stress
CN118879582B (zh) * 2024-09-19 2025-03-25 微康益生菌(苏州)股份有限公司 一种细胞完整、分散均匀、稳定性强的后生元制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
RU2152993C1 (ru) * 1999-11-30 2000-07-20 Государственный научный центр РФ Институт медико-биологических проблем Штамм bifidobacterium bifidum вкпм ас-1578, используемый для приготовления бактериальных препаратов и продуктов питания
RU2184146C1 (ru) * 2001-01-29 2002-06-27 Закрытое акционерное общество "Партнер" Штамм bifidobacterium bifidum 45 вкпм ас-1621, используемый для приготовления бактериальных препаратов и продуктов питания
DE602004006133T3 (de) * 2003-06-30 2014-12-24 Clasado Inc. Neue galactooligosaccharidzusammensetzung und herstellung davon
PL1673100T3 (pl) * 2004-08-05 2008-01-31 Anidral Srl Szczepy bakterii Bifidobacterium wytwarzające kwas foliowy, preparaty i ich zastosowanie
AR053805A1 (es) * 2005-05-31 2007-05-23 Iams Company Bifidobacterias probioticas para felinos
CN100490826C (zh) * 2005-07-05 2009-05-27 广州市微生物研究所 多联活性双歧杆菌产品的制备方法
JP4881304B2 (ja) * 2005-07-21 2012-02-22 株式会社ヤクルト本社 新規ビフィドバクテリウム属細菌及びその利用
US9084434B2 (en) * 2006-09-27 2015-07-21 Little Calumet Holdings Llc Probiotic oral dosage forms
CN101636173A (zh) * 2007-03-27 2010-01-27 宝洁公司 施用益生菌剂的方法及试剂盒
DK2270133T3 (en) * 2008-04-22 2015-09-07 Corporación Alimentaria Peñasanta Capsa Method of obtaining a new strain of Bifidobacterium bidifum with effect against infection with Helicobacter pylori
RU2010143460A (ru) * 2008-05-01 2012-06-10 Дзе Проктер Энд Гэмбл Компани (US) Способы и наборы для терапии восстановительных состояний кишечника
WO2009151329A1 (en) * 2008-06-13 2009-12-17 N.V. Nutricia Nutrition for prevention of infections

Also Published As

Publication number Publication date
PT2481299T (pt) 2017-03-08
EP2481299A1 (en) 2012-08-01
EP2481299B1 (en) 2016-12-07
JP5956467B2 (ja) 2016-07-27
HUE033189T2 (en) 2017-11-28
NZ613544A (en) 2014-10-31
PL2481299T3 (pl) 2017-09-29
WO2012104226A1 (en) 2012-08-09
BR112013019258A8 (pt) 2017-09-19
BR112013019258A2 (pt) 2016-10-11
ES2610908T3 (es) 2017-05-04
CN103476273A (zh) 2013-12-25
US20140056852A1 (en) 2014-02-27
JP2014505065A (ja) 2014-02-27
RU2603285C2 (ru) 2016-11-27
US9408879B2 (en) 2016-08-09
HRP20161792T1 (hr) 2017-03-10
CA2825980A1 (en) 2012-08-09
BR112013019258B1 (pt) 2021-09-08
AU2012213576B2 (en) 2015-07-23
DK2481299T3 (en) 2017-02-06
RU2013137404A (ru) 2015-03-10

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