|
US2234705A
(en)
|
1940-04-12 |
1941-03-11 |
Eastman Kodak Co |
Cellulose organic derivative composition containing esters of monoalkoxy benzoic acids
|
|
US2413258A
(en)
|
1942-07-07 |
1946-12-24 |
United Gas Improvement Co |
Polystyrene-type resins plasticized with high boiling fatty acid alkyl esters
|
|
FR1579473A
(enExample)
|
1966-10-21 |
1969-08-29 |
|
|
|
DE2413258A1
(de)
|
1974-03-20 |
1975-10-02 |
Bayer Ag |
Alkoxycarbonylphenylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung als herbizide
|
|
IL46853A0
(en)
|
1974-03-20 |
1975-05-22 |
Bayer Ag |
Novel alkoxycarbonylphenylureas,their preparation and their use as herbicides
|
|
GB1573212A
(en)
|
1976-04-15 |
1980-08-20 |
Technicon Instr |
Immunoassay for gentamicin
|
|
US4664504A
(en)
|
1983-01-20 |
1987-05-12 |
Tokyo Shibaura Denki Kabushiki Kaisha |
Image forming apparatus
|
|
US4568649A
(en)
|
1983-02-22 |
1986-02-04 |
Immunex Corporation |
Immediate ligand detection assay
|
|
US4626513A
(en)
|
1983-11-10 |
1986-12-02 |
Massachusetts General Hospital |
Method and apparatus for ligand detection
|
|
AU567140B2
(en)
|
1984-01-06 |
1987-11-12 |
Shionogi & Co., Ltd. |
Sulphonamido-benzamide derivatives
|
|
ATE56096T1
(de)
|
1984-03-15 |
1990-09-15 |
Immunex Corp |
Test zur sofortigen feststellung von liganden, testsatz und seine herstellung.
|
|
IT1196133B
(it)
|
1984-06-06 |
1988-11-10 |
Ausonia Farma Srl |
Derivati furanici con attivita' antiulcera
|
|
US4714693A
(en)
|
1986-04-03 |
1987-12-22 |
Uop Inc. |
Method of making a catalyst composition comprising uniform size metal components on carrier
|
|
DE3642315A1
(de)
|
1986-12-11 |
1988-06-23 |
Boehringer Mannheim Gmbh |
Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
|
|
US5688655A
(en)
|
1988-02-10 |
1997-11-18 |
Ict Pharmaceuticals, Inc. |
Method of screening for protein inhibitors and activators
|
|
US5700637A
(en)
|
1988-05-03 |
1997-12-23 |
Isis Innovation Limited |
Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
|
|
US6054270A
(en)
|
1988-05-03 |
2000-04-25 |
Oxford Gene Technology Limited |
Analying polynucleotide sequences
|
|
US5658775A
(en)
|
1988-05-17 |
1997-08-19 |
Sloan-Kettering Institute For Cancer Research |
Double copy retroviral vector
|
|
JP2528706B2
(ja)
|
1988-05-30 |
1996-08-28 |
ゼリア新薬工業株式会社 |
ジヒドロピリジン化合物の製剤組成物
|
|
WO1990002806A1
(en)
|
1988-09-01 |
1990-03-22 |
Whitehead Institute For Biomedical Research |
Recombinant retroviruses with amphotropic and ecotropic host ranges
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US5527681A
(en)
|
1989-06-07 |
1996-06-18 |
Affymax Technologies N.V. |
Immobilized molecular synthesis of systematically substituted compounds
|
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5800992A
(en)
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
|
AU7906691A
(en)
|
1990-05-23 |
1991-12-10 |
United States of America, as represented by the Secretary, U.S. Department of Commerce, The |
Adeno-associated virus (aav)-based eucaryotic vectors
|
|
DE4022414A1
(de)
|
1990-07-13 |
1992-01-16 |
Bayer Ag |
Substituierte pyrrolo-pyridine
|
|
EP0580860B2
(en)
|
1991-04-16 |
2004-12-15 |
Nippon Shinyaku Company, Limited |
Method of manufacturing solid dispersion
|
|
EP0659209A1
(en)
|
1991-07-26 |
1995-06-28 |
The University Of Rochester |
Cancer therapy utilizing malignant cells
|
|
US5632957A
(en)
|
1993-11-01 |
1997-05-27 |
Nanogen |
Molecular biological diagnostic systems including electrodes
|
|
GB9127531D0
(en)
|
1991-12-31 |
1992-02-19 |
Fujisawa Pharmaceutical Co |
Heterocyclic compound
|
|
FR2687402B1
(fr)
|
1992-02-14 |
1995-06-30 |
Lipha |
Nouveaux azaindoles, procedes de preparation et medicaments les contenant.
|
|
JPH05236997A
(ja)
|
1992-02-28 |
1993-09-17 |
Hitachi Ltd |
ポリヌクレオチド捕捉用チップ
|
|
JPH06135946A
(ja)
|
1992-10-30 |
1994-05-17 |
Otsuka Pharmaceut Co Ltd |
ピラジン誘導体
|
|
AU686115B2
(en)
|
1992-11-02 |
1998-02-05 |
Fujisawa Pharmaceutical Co., Ltd. |
Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation
|
|
GB9226855D0
(en)
|
1992-12-23 |
1993-02-17 |
Erba Carlo Spa |
Vinylene-azaindole derivatives and process for their preparation
|
|
CN1118598A
(zh)
|
1993-03-01 |
1996-03-13 |
默克·夏普-道姆公司 |
吡咯并吡啶衍生物
|
|
ES2134929T3
(es)
|
1993-03-01 |
1999-10-16 |
Merck Sharp & Dohme |
Derivados de pirrolo-piridina como ligandos para receptores de dopamina.
|
|
US5576319A
(en)
|
1993-03-01 |
1996-11-19 |
Merck, Sharp & Dohme Ltd. |
Pyrrolo-pyridine derivatives
|
|
JPH09500357A
(ja)
|
1993-03-01 |
1997-01-14 |
メルク シヤープ エンド ドーム リミテツド |
ピロロ−ピリジン誘導体
|
|
US5840485A
(en)
|
1993-05-27 |
1998-11-24 |
Selectide Corporation |
Topologically segregated, encoded solid phase libraries
|
|
DK0705279T3
(da)
|
1993-05-27 |
2003-06-10 |
Selectide Corp |
Topologisk adskilte, kodende fastfase-biblioteker
|
|
IT1265057B1
(it)
|
1993-08-05 |
1996-10-28 |
Dompe Spa |
Tropil 7-azaindolil-3-carbossiamidi
|
|
US5631236A
(en)
|
1993-08-26 |
1997-05-20 |
Baylor College Of Medicine |
Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk
|
|
US5426039A
(en)
|
1993-09-08 |
1995-06-20 |
Bio-Rad Laboratories, Inc. |
Direct molecular cloning of primer extended DNA containing an alkane diol
|
|
GB9319297D0
(en)
|
1993-09-17 |
1993-11-03 |
Wellcome Found |
Indole derivatives
|
|
US6045996A
(en)
|
1993-10-26 |
2000-04-04 |
Affymetrix, Inc. |
Hybridization assays on oligonucleotide arrays
|
|
US5965452A
(en)
|
1996-07-09 |
1999-10-12 |
Nanogen, Inc. |
Multiplexed active biologic array
|
|
US6468742B2
(en)
|
1993-11-01 |
2002-10-22 |
Nanogen, Inc. |
Methods for determination of single nucleic acid polymorphisms using bioelectronic microchip
|
|
US5486525A
(en)
|
1993-12-16 |
1996-01-23 |
Abbott Laboratories |
Platelet activating factor antagonists: imidazopyridine indoles
|
|
EP1195372A1
(en)
|
1994-04-18 |
2002-04-10 |
Mitsubishi Pharma Corporation |
N-heterocyclic substituted benzamide derivatives with antihypertensive activity
|
|
GB9408577D0
(en)
|
1994-04-29 |
1994-06-22 |
Fujisawa Pharmaceutical Co |
New compound
|
|
US5807522A
(en)
|
1994-06-17 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for fabricating microarrays of biological samples
|
|
GB9412719D0
(en)
|
1994-06-24 |
1994-08-17 |
Erba Carlo Spa |
Substituted azaindolylidene compounds and process for their preparation
|
|
US5763198A
(en)
|
1994-07-22 |
1998-06-09 |
Sugen, Inc. |
Screening assays for compounds
|
|
DE69515177T2
(de)
|
1994-08-10 |
2000-10-05 |
Merck Sharp & Dohme Ltd., Hoddesdon |
Tetrahydropyridinylmethylderivate von pyrrolo[2,3-b]pyridine
|
|
GB9416189D0
(en)
|
1994-08-10 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9416162D0
(en)
|
1994-08-10 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9420521D0
(en)
|
1994-10-12 |
1994-11-30 |
Smithkline Beecham Plc |
Novel compounds
|
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
|
US5830645A
(en)
|
1994-12-09 |
1998-11-03 |
The Regents Of The University Of California |
Comparative fluorescence hybridization to nucleic acid arrays
|
|
US5837815A
(en)
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
|
GB9503400D0
(en)
|
1995-02-21 |
1995-04-12 |
Merck Sharp & Dohme |
Therpeutic agents
|
|
GB2298199A
(en)
|
1995-02-21 |
1996-08-28 |
Merck Sharp & Dohme |
Synthesis of azaindoles
|
|
US5959098A
(en)
|
1996-04-17 |
1999-09-28 |
Affymetrix, Inc. |
Substrate preparation process
|
|
US6117681A
(en)
|
1995-03-29 |
2000-09-12 |
Bavarian Nordic Research Inst. A/S |
Pseudotyped retroviral particles
|
|
GB9507291D0
(en)
|
1995-04-07 |
1995-05-31 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB2299581A
(en)
|
1995-04-07 |
1996-10-09 |
Merck Sharp & Dohme |
3-(Tetrahydropyridin-1-yl-methyl)pyrrolo[2,3-b]pyridine derivatives as ligands for dopamine receptor subtypes
|
|
GB9511220D0
(en)
|
1995-06-02 |
1995-07-26 |
Glaxo Group Ltd |
Solid dispersions
|
|
US6110456A
(en)
|
1995-06-07 |
2000-08-29 |
Yale University |
Oral delivery or adeno-associated viral vectors
|
|
US5856174A
(en)
|
1995-06-29 |
1999-01-05 |
Affymetrix, Inc. |
Integrated nucleic acid diagnostic device
|
|
AU6526896A
(en)
|
1995-07-22 |
1997-02-18 |
Rhone-Poulenc Rorer Limited |
Substituted aromatic compounds and their pharmaceutical use
|
|
US5866411A
(en)
|
1995-09-08 |
1999-02-02 |
Pedersen; Finn Skou |
Retroviral vector, a replication system for said vector and avian or mammalian cells transfected with said vector
|
|
US5747276A
(en)
|
1995-09-15 |
1998-05-05 |
The Scripps Research Institute |
Screening methods for the identification of novel antibiotics
|
|
US5721118A
(en)
|
1995-10-31 |
1998-02-24 |
The Regents Of The University Of California, San Diego |
Mammalian artificial chromosomes and methods of using same
|
|
US6022963A
(en)
|
1995-12-15 |
2000-02-08 |
Affymetrix, Inc. |
Synthesis of oligonucleotide arrays using photocleavable protecting groups
|
|
US6013440A
(en)
|
1996-03-11 |
2000-01-11 |
Affymetrix, Inc. |
Nucleic acid affinity columns
|
|
US6025155A
(en)
|
1996-04-10 |
2000-02-15 |
Chromos Molecular Systems, Inc. |
Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
|
|
US5804585A
(en)
|
1996-04-15 |
1998-09-08 |
Texas Biotechnology Corporation |
Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
|
|
US5725838A
(en)
|
1996-05-31 |
1998-03-10 |
Resolution Pharmaceuticals, Inc. |
Radiolabeled D4 receptor ligands
|
|
AU3568897A
(en)
|
1996-06-07 |
1998-01-05 |
Eos Biotechnology, Inc. |
Immobilised linear oligonucleotide arrays
|
|
EP0923577A2
(en)
|
1996-06-25 |
1999-06-23 |
Takeda Chemical Industries, Ltd. |
Oxazolone derivatives and their use as anti-helicobacter pylori agent
|
|
BR9711154A
(pt)
|
1996-08-12 |
1999-08-17 |
Yoshitomi Pharmaceutical |
Agente farmac-utico contendo inibidor cinase rho
|
|
JPH10130269A
(ja)
|
1996-09-04 |
1998-05-19 |
Nippon Chemiphar Co Ltd |
カルボリン誘導体
|
|
JPH1087629A
(ja)
|
1996-09-18 |
1998-04-07 |
Fujisawa Pharmaceut Co Ltd |
新規イソキノリン誘導体、およびその医薬用途
|
|
US6180643B1
(en)
|
1996-11-19 |
2001-01-30 |
Amgen Inc. |
Aryl and heteroaryl substituted fused pyrrole antiinflammatory agents
|
|
US6294330B1
(en)
|
1997-01-31 |
2001-09-25 |
Odyssey Pharmaceuticals Inc. |
Protein fragment complementation assays for the detection of biological or drug interactions
|
|
AU6443498A
(en)
|
1997-03-07 |
1998-09-22 |
Tropix, Inc. |
Protease inhibtor assay
|
|
US5977131A
(en)
|
1997-04-09 |
1999-11-02 |
Pfizer Inc. |
Azaindole-ethylamine derivatives as nicotinic acetylcholine receptor binding agents
|
|
WO1998047899A1
(en)
|
1997-04-24 |
1998-10-29 |
Ortho-Mcneil Corporation, Inc. |
Substituted pyrrolopyridines useful in the treatment of inflammatory diseases
|
|
US6096718A
(en)
|
1997-06-05 |
2000-08-01 |
Gene Targeting Corp. |
Tissue specific adenovirus vectors for breast cancer treatment
|
|
SG72827A1
(en)
|
1997-06-23 |
2000-05-23 |
Hoffmann La Roche |
Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
|
|
WO1999000386A1
(en)
|
1997-06-27 |
1999-01-07 |
Resolution Pharmaceuticals Inc. |
Dopamine d4 receptor ligands
|
|
US6235769B1
(en)
|
1997-07-03 |
2001-05-22 |
Sugen, Inc. |
Methods of preventing and treating neurological disorders with compounds that modulate the function of the C-RET receptor protein tyrosine kinase
|
|
US6826296B2
(en)
|
1997-07-25 |
2004-11-30 |
Affymetrix, Inc. |
Method and system for providing a probe array chip design database
|
|
PT901786E
(pt)
|
1997-08-11 |
2007-08-07 |
Pfizer Prod Inc |
Disperções farmacêuticas sólidas com biodisponibilidade melhorada
|
|
US6161776A
(en)
|
1997-08-12 |
2000-12-19 |
Nibco Inc. |
Multi-layered, porous mat turf irrigation apparatus and method
|
|
AU8908198A
(en)
|
1997-08-15 |
1999-03-08 |
Hyseq, Inc. |
Methods and compositions for detection or quantification of nucleic acid species
|
|
ES2225407T3
(es)
|
1997-09-11 |
2005-03-16 |
Bioventures, Inc. |
Metodo para producir disposiciones ordenadas de alta densidad.
|
|
US6178384B1
(en)
|
1997-09-29 |
2001-01-23 |
The Trustees Of Columbia University In The City Of New York |
Method and apparatus for selecting a molecule based on conformational free energy
|
|
US6465178B2
(en)
|
1997-09-30 |
2002-10-15 |
Surmodics, Inc. |
Target molecule attachment to surfaces
|
|
AU1529799A
(en)
|
1997-12-23 |
1999-07-12 |
Warner-Lambert Company |
Thiourea and benzamide compounds, compositions and methods of treating or preventing inflammatory diseases and atherosclerosis
|
|
AU3368299A
(en)
|
1998-04-02 |
1999-10-25 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
CA2325995A1
(en)
|
1998-04-02 |
1999-10-14 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
EP1067930A4
(en)
|
1998-04-02 |
2002-09-18 |
Merck & Co Inc |
GONADOLIBER'S ANTAGONISTS
|
|
CA2326140A1
(en)
|
1998-04-02 |
1999-10-14 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
WO1999051595A1
(en)
|
1998-04-02 |
1999-10-14 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
JP2002510630A
(ja)
|
1998-04-02 |
2002-04-09 |
メルク エンド カムパニー インコーポレーテッド |
性腺刺激ホルモン放出ホルモン拮抗薬
|
|
WO1999051773A1
(en)
|
1998-04-03 |
1999-10-14 |
Phylos, Inc. |
Addressable protein arrays
|
|
US6048695A
(en)
|
1998-05-04 |
2000-04-11 |
Baylor College Of Medicine |
Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
|
|
US6288234B1
(en)
|
1998-06-08 |
2001-09-11 |
Advanced Medicine, Inc. |
Multibinding inhibitors of microsomal triglyceride transferase protein
|
|
US6113913A
(en)
|
1998-06-26 |
2000-09-05 |
Genvec, Inc. |
Recombinant adenovirus
|
|
US6673812B1
(en)
|
1998-08-17 |
2004-01-06 |
Senju Pharmaceutical Co., Ltd. |
Preventives/remedies for glaucoma
|
|
ATE253580T1
(de)
|
1998-08-28 |
2003-11-15 |
Astrazeneca Ab |
Neue thieno(2,3-d)pyrimidindione, verfahren für ihre herstellung und ihre verwendung in der therapie
|
|
WO2000012074A2
(en)
|
1998-08-28 |
2000-03-09 |
Scios Inc. |
Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase
|
|
HK1039325B
(en)
|
1998-09-18 |
2006-02-24 |
Abbott Gmbh & Co. Kg |
4-aminopyrrolopyrimidines as kinase inhibitors
|
|
US6350786B1
(en)
|
1998-09-22 |
2002-02-26 |
Hoffmann-La Roche Inc. |
Stable complexes of poorly soluble compounds in ionic polymers
|
|
US6277628B1
(en)
|
1998-10-02 |
2001-08-21 |
Incyte Genomics, Inc. |
Linear microarrays
|
|
IT1303759B1
(it)
|
1998-11-17 |
2001-02-23 |
Dompe Spa |
Procedimento migliorato per la preparazione di acido 7-azaindolil-3-carbossilico.
|
|
US6277489B1
(en)
|
1998-12-04 |
2001-08-21 |
The Regents Of The University Of California |
Support for high performance affinity chromatography and other uses
|
|
US20010001449A1
(en)
|
1998-12-30 |
2001-05-24 |
Thomas R. Kiliany |
Low-pressure hydrocracking process
|
|
CN1198803C
(zh)
|
1999-03-05 |
2005-04-27 |
第一三得利制药株式会社 |
具有激活烟碱性乙酰胆碱α4β2受体作用的杂环化合物
|
|
HUP0105114A3
(en)
|
1999-03-17 |
2002-09-30 |
Astrazeneca Ab |
Quinazolinone derivatives, pharmaceutical compositions containing them, their use and process for their preparation
|
|
AR028475A1
(es)
|
1999-04-22 |
2003-05-14 |
Wyeth Corp |
Derivados de azaindol y uso de los mismos para la manufactura de un medicamento para el tratamiento de la depresion.
|
|
US6653309B1
(en)
|
1999-04-26 |
2003-11-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme technical field of the invention
|
|
US6221653B1
(en)
|
1999-04-27 |
2001-04-24 |
Agilent Technologies, Inc. |
Method of performing array-based hybridization assays using thermal inkjet deposition of sample fluids
|
|
FR2793793B1
(fr)
|
1999-05-19 |
2004-02-27 |
Adir |
Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US6492406B1
(en)
|
1999-05-21 |
2002-12-10 |
Astrazeneca Ab |
Pharmaceutically active compounds
|
|
TWI234557B
(en)
|
1999-05-26 |
2005-06-21 |
Telik Inc |
Novel naphthalene ureas as glucose uptake enhancers
|
|
CZ20014244A3
(cs)
|
1999-06-03 |
2002-07-17 |
Knoll Gmbh |
Benzotiazinonové a benzoxazinonové sloučeniny
|
|
IL147757A0
(en)
|
1999-07-30 |
2002-08-14 |
Abbott Gmbh & Co Kg |
2-pyrazolin-5-ones
|
|
US6653151B2
(en)
|
1999-07-30 |
2003-11-25 |
Large Scale Proteomics Corporation |
Dry deposition of materials for microarrays using matrix displacement
|
|
WO2001024236A1
(en)
|
1999-09-27 |
2001-04-05 |
Infineon Technologies North America Corp. |
Semiconductor structures having a capacitor and manufacturing methods
|
|
GB9924962D0
(en)
|
1999-10-21 |
1999-12-22 |
Mrc Collaborative Centre |
Allosteric sites on muscarinic receptors
|
|
US20010008765A1
(en)
|
1999-12-06 |
2001-07-19 |
Fuji Photo Film Co., Ltd. |
DNA chip and reactive solid carrier
|
|
CA2395520A1
(en)
|
1999-12-21 |
2001-06-28 |
Sugen, Inc. |
4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors
|
|
ES2267605T3
(es)
|
1999-12-22 |
2007-03-16 |
Sugen, Inc. |
Uso de compuestos de indolinona para la fabricacion de productos farmaceuticos destinados a modular la funcion de la c-kit-tirosina-proteina-quinasa.
|
|
FR2805259B1
(fr)
|
2000-02-17 |
2002-03-29 |
Inst Nat Sante Rech Med |
Nouveaux derives d'aminoacides n-mercaptoacyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US20020061892A1
(en)
|
2000-02-22 |
2002-05-23 |
Tao Wang |
Antiviral azaindole derivatives
|
|
JP2001278886A
(ja)
|
2000-03-28 |
2001-10-10 |
Dai Ichi Seiyaku Co Ltd |
ベンゾオキサジン誘導体及びこれを含有する医薬
|
|
GB0007934D0
(en)
|
2000-03-31 |
2000-05-17 |
Darwin Discovery Ltd |
Chemical compounds
|
|
US6335342B1
(en)
|
2000-06-19 |
2002-01-01 |
Pharmacia & Upjohn S.P.A. |
Azaindole derivatives, process for their preparation, and their use as antitumor agents
|
|
WO2002000657A2
(en)
|
2000-06-26 |
2002-01-03 |
Lilly Icos Llc |
Condensed pyrazindione derivatives
|
|
SK2002003A3
(en)
|
2000-08-31 |
2004-04-06 |
Pfizer Prod Inc |
Pyrazole derivatives and their use as protein kinase inhibitors
|
|
KR20030077042A
(ko)
|
2001-02-27 |
2003-09-29 |
아스트라제네카 아베 |
비칼루타마이드를 포함하는 약학 제제
|
|
US7109208B2
(en)
|
2001-04-11 |
2006-09-19 |
Senju Pharmaceutical Co., Ltd. |
Visual function disorder improving agents
|
|
WO2002085896A1
(en)
|
2001-04-24 |
2002-10-31 |
Wyeth |
Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan
|
|
GB0114417D0
(en)
|
2001-06-13 |
2001-08-08 |
Boc Group Plc |
Lubricating systems for regenerative vacuum pumps
|
|
EP1267111A1
(en)
|
2001-06-15 |
2002-12-18 |
Dsm N.V. |
Pressurized fluid conduit
|
|
WO2002102783A1
(en)
|
2001-06-19 |
2002-12-27 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
US7291639B2
(en)
|
2001-06-20 |
2007-11-06 |
Wyeth |
Aryloxy-acetic acid compounds useful as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
|
|
GB0115109D0
(en)
|
2001-06-21 |
2001-08-15 |
Aventis Pharma Ltd |
Chemical compounds
|
|
SE0102300D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
US20030091974A1
(en)
|
2001-06-29 |
2003-05-15 |
Alain Moussy |
Method for screening compounds capable of depleting mast cells
|
|
SE0102439D0
(sv)
|
2001-07-05 |
2001-07-05 |
Astrazeneca Ab |
New compounds
|
|
UA75425C2
(en)
|
2001-07-09 |
2006-04-17 |
|
Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds
|
|
GB0117583D0
(en)
|
2001-07-19 |
2001-09-12 |
Astrazeneca Ab |
Novel compounds
|
|
US6858860B2
(en)
|
2001-07-24 |
2005-02-22 |
Seiko Epson Corporation |
Apparatus and method for measuring natural period of liquid
|
|
GB0118479D0
(en)
|
2001-07-28 |
2001-09-19 |
Astrazeneca Ab |
Novel compounds
|
|
WO2003020698A2
(en)
|
2001-09-06 |
2003-03-13 |
Prochon Biotech Ltd. |
Protein tyrosine kinase inhibitors
|
|
WO2003028724A1
(en)
|
2001-10-04 |
2003-04-10 |
Smithkline Beecham Corporation |
Chk1 kinase inhibitors
|
|
US20050014942A1
(en)
|
2001-10-30 |
2005-01-20 |
Yasufumi Maruyama |
Amide derivatives and drugs
|
|
US20030119839A1
(en)
|
2001-12-13 |
2003-06-26 |
Nan-Horng Lin |
Protein kinase inhibitors
|
|
MXPA04007459A
(es)
|
2002-02-01 |
2005-09-08 |
Astrazeneca Ab |
Compuestos de quinazolina.
|
|
US20030236277A1
(en)
|
2002-02-14 |
2003-12-25 |
Kadow John F. |
Indole, azaindole and related heterocyclic pyrrolidine derivatives
|
|
US6884889B2
(en)
|
2002-03-25 |
2005-04-26 |
Bristol-Myers Squibb Co. |
Processes for the preparation of antiviral 7-azaindole derivatives
|
|
KR20040111445A
(ko)
|
2002-03-28 |
2004-12-31 |
에자이 가부시키가이샤 |
신경퇴행성 질환 치료용 ｃ─Ｊｕｎ Ｎ─말단 키나아제억제제로서의 ７─아자인돌
|
|
IL164082A0
(en)
|
2002-03-28 |
2005-12-18 |
Eisai Co Ltd |
Azaindole derivatives and pharmaceutical compositions containing the same
|
|
EP1495016A2
(en)
|
2002-04-09 |
2005-01-12 |
Astex Technology Limited |
Heterocyclic compounds and their use as modulators of p38 map kinase
|
|
UA78999C2
(en)
|
2002-06-04 |
2007-05-10 |
Wyeth Corp |
1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
|
|
US7361665B2
(en)
|
2002-07-09 |
2008-04-22 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases
|
|
TW200403243A
(en)
|
2002-07-18 |
2004-03-01 |
Wyeth Corp |
1-Heterocyclylalkyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
|
|
TWI329112B
(en)
|
2002-07-19 |
2010-08-21 |
Bristol Myers Squibb Co |
Novel inhibitors of kinases
|
|
EP1388341A1
(en)
|
2002-08-07 |
2004-02-11 |
Aventis Pharma Deutschland GmbH |
Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals
|
|
US6878887B2
(en)
|
2002-08-07 |
2005-04-12 |
Matsushita Electric Industrial Co., Ltd. |
Anti-malfunction mechanism for variable output device
|
|
SE0202463D0
(sv)
|
2002-08-14 |
2002-08-14 |
Astrazeneca Ab |
Novel compounds
|
|
BR122012021252B8
(pt)
|
2002-09-06 |
2021-05-25 |
Cerulean Pharma Inc |
polímeros à base de ciclodextrina para o fornecimento de agentes terapêuticos ligados a eles por covalência
|
|
AU2003272548A1
(en)
|
2002-09-16 |
2004-04-30 |
Plexxikon, Inc. |
Crystal structure of pim-1 kinase
|
|
US7183241B2
(en)
|
2002-10-15 |
2007-02-27 |
Exxonmobil Research And Engineering Company |
Long life lubricating oil composition with very low phosphorus content
|
|
SE0203654D0
(sv)
|
2002-12-09 |
2002-12-09 |
Astrazeneca Ab |
New compounds
|
|
WO2004054581A2
(en)
|
2002-12-13 |
2004-07-01 |
Smithkline Beecham Corporation |
Cyclohexyl compounds as ccr5 antagonists
|
|
US7696225B2
(en)
|
2003-01-06 |
2010-04-13 |
Osi Pharmaceuticals, Inc. |
(2-carboxamido)(3-Amino) thiophene compounds
|
|
SE0300119D0
(sv)
|
2003-01-17 |
2003-01-17 |
Astrazeneca Ab |
Novel compounds
|
|
SE0300120D0
(sv)
|
2003-01-17 |
2003-01-17 |
Astrazeneca Ab |
Novel compounds
|
|
US20050085463A1
(en)
|
2003-01-23 |
2005-04-21 |
Weiner David M. |
Use of N-desmethylclozapine to treat human neuropsychiatric disease
|
|
CN100594023C
(zh)
|
2003-02-03 |
2010-03-17 |
诺瓦提斯公司 |
药物制剂
|
|
JP2006517966A
(ja)
|
2003-02-14 |
2006-08-03 |
ワイス |
５−ヒドロキシトリプタミン−６リガンドとしてのヘテロサイクリル−３−スルホニルアザインドールまたは−アザインダゾール誘導体
|
|
JP2007524374A
(ja)
|
2003-02-28 |
2007-08-30 |
プレキシコン，インコーポレーテッド |
Ｐｙｋ２結晶構造および使用
|
|
WO2004078756A2
(en)
|
2003-03-06 |
2004-09-16 |
Eisai Co., Ltd. |
Jnk inhibitors
|
|
US7612086B2
(en)
|
2003-05-16 |
2009-11-03 |
Eisai R & D Management Co. Ltd. |
JNK inhibitors
|
|
CL2004001884A1
(es)
|
2003-08-04 |
2005-06-03 |
Pfizer Prod Inc |
Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
|
|
AR045595A1
(es)
|
2003-09-04 |
2005-11-02 |
Vertex Pharma |
Composiciones utiles como inhibidores de proteinas quinasas
|
|
WO2005044181A2
(en)
|
2003-09-09 |
2005-05-19 |
Temple University-Of The Commonwealth System Of Higher Education |
Protection of tissues and cells from cytotoxic effects of ionizing radiation by abl inhibitors
|
|
WO2005028624A2
(en)
|
2003-09-15 |
2005-03-31 |
Plexxikon, Inc. |
Molecular scaffolds for kinase ligand development
|
|
EP1667983A4
(en)
|
2003-09-23 |
2010-07-21 |
Merck Sharp & Dohme |
PYRAZOL MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS
|
|
CA2542105C
(en)
|
2003-10-08 |
2011-08-02 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
DE10357510A1
(de)
|
2003-12-09 |
2005-07-07 |
Bayer Healthcare Ag |
Heteroarylsubstituierte Benzole
|
|
ES2527118T3
(es)
|
2003-12-19 |
2015-01-20 |
Plexxikon Inc. |
Compuestos y procedimientos de desarrollo de moduladores de Ret
|
|
BRPI0417533B1
(pt)
|
2003-12-24 |
2016-03-01 |
Danisco |
enzima variante glicolipídio aciltransferase, uso e método para sua produção, método para o preparo de um produto alimentício e produto assado de farinha, processo de refinamento enzimático
|
|
GB0330042D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
|
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
|
GB0403635D0
(en)
|
2004-02-18 |
2004-03-24 |
Devgen Nv |
Pyridinocarboxamides with improved activity as kinase inhibitors
|
|
GB0405055D0
(en)
|
2004-03-05 |
2004-04-07 |
Eisai London Res Lab Ltd |
JNK inhibitors
|
|
EP1722789A2
(en)
|
2004-03-08 |
2006-11-22 |
Amgen Inc. |
Therapeutic modulation of ppar (gamma) activity
|
|
KR20050091462A
(ko)
|
2004-03-12 |
2005-09-15 |
한국과학기술연구원 |
푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제
|
|
PT1730146E
(pt)
|
2004-03-30 |
2011-07-11 |
Vertex Pharma |
Azaindoles úteis como inibidores de jak e outras proteínas quinases
|
|
AR049333A1
(es)
|
2004-04-02 |
2006-07-19 |
Vertex Pharma |
Azaindoles inhibidores de proteinquinasas rock y otras proteinas quinasas. composiciones farmaceuticas.
|
|
EP1773305A2
(en)
|
2004-05-25 |
2007-04-18 |
Yale University Corporation |
Method for treating skeletal disorders resulting from fgfr malfunction
|
|
US20090105218A1
(en)
|
2004-05-29 |
2009-04-23 |
7Tm Pharma A/S |
CRTH2 Receptor Ligands For Therapeutic Use
|
|
TW200616632A
(en)
|
2004-06-17 |
2006-06-01 |
Plexxikon Inc |
Compounds modulating c-kit activity and uses therefor
|
|
US7498342B2
(en)
|
2004-06-17 |
2009-03-03 |
Plexxikon, Inc. |
Compounds modulating c-kit activity
|
|
EP2325184A1
(en)
|
2004-06-30 |
2011-05-25 |
Vertex Pharmceuticals Incorporated |
Azaindoles useful as inhibitors of protein kinases
|
|
US7140816B2
(en)
|
2004-07-20 |
2006-11-28 |
H&S Tool, Inc. |
Multi-functional tube milling head
|
|
KR20070053237A
(ko)
|
2004-07-27 |
2007-05-23 |
에스지엑스 파마슈티컬스, 인코포레이티드 |
피롤로-피리딘 키나제 조절제
|
|
US7361764B2
(en)
|
2004-07-27 |
2008-04-22 |
Sgx Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
AU2005269387A1
(en)
|
2004-07-27 |
2006-02-09 |
Sgx Pharmaceuticals, Inc. |
Fused ring heterocycle kinase modulators
|
|
US7709645B2
(en)
|
2004-07-27 |
2010-05-04 |
Sgx Pharmaceuticals, Inc. |
Pyrrolo-pyridine kinase modulators
|
|
US7626021B2
(en)
|
2004-07-27 |
2009-12-01 |
Sgx Pharmaceuticals, Inc. |
Fused ring heterocycle kinase modulators
|
|
US20060024361A1
(en)
|
2004-07-28 |
2006-02-02 |
Isa Odidi |
Disintegrant assisted controlled release technology
|
|
WO2006010637A2
(en)
|
2004-07-30 |
2006-02-02 |
Gpc Biotech Ag |
Pyridinylamines
|
|
JP4954086B2
(ja)
|
2004-12-08 |
2012-06-13 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
１ｈ−ピロロ［２，３−ｂ］ピリジン
|
|
EP1874769B1
(de)
|
2005-04-25 |
2011-09-14 |
Merck Patent GmbH |
Neuartige aza-heterozyklen als kinase-inhibitoren
|
|
FR2884821B1
(fr)
|
2005-04-26 |
2007-07-06 |
Aventis Pharma Sa |
Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
|
|
NZ563444A
(en)
|
2005-05-17 |
2011-04-29 |
Plexxikon Inc |
Pyrrolo(2,3-b)pyridine derivatives as protein kinase inhibitors
|
|
EP1881983B1
(en)
|
2005-05-20 |
2012-01-11 |
Vertex Pharmaceuticals, Inc. |
Pyrrolopyridines useful as inhibitors of protein kinase
|
|
WO2006127941A2
(en)
|
2005-05-23 |
2006-11-30 |
Teva Pharmaceutical Industries Ltd. |
Amorphous cinacalcet hydrochloride and preparation thereof
|
|
WO2006137376A1
(ja)
|
2005-06-21 |
2006-12-28 |
Mitsui Chemicals, Inc. |
アミド誘導体ならびに該化合物を含有する殺虫剤
|
|
UA95244C2
(ru)
|
2005-06-22 |
2011-07-25 |
Плексикон, Инк. |
Соединения и способ модулирования активности киназ, и показания для их применения
|
|
GB0516156D0
(en)
|
2005-08-05 |
2005-09-14 |
Eisai London Res Lab Ltd |
JNK inhibitors
|
|
US7754717B2
(en)
|
2005-08-15 |
2010-07-13 |
Amgen Inc. |
Bis-aryl amide compounds and methods of use
|
|
AU2007226983A1
(en)
|
2006-03-20 |
2007-09-27 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions
|
|
US7963673B2
(en)
|
2006-05-30 |
2011-06-21 |
Finn Bruce L |
Versatile illumination system
|
|
EP3048099A3
(en)
|
2006-11-15 |
2016-09-21 |
YM BioSciences Australia Pty Ltd |
Inhibitors of kinase activity
|
|
WO2008063888A2
(en)
|
2006-11-22 |
2008-05-29 |
Plexxikon, Inc. |
Compounds modulating c-fms and/or c-kit activity and uses therefor
|
|
PE20081581A1
(es)
|
2006-12-21 |
2008-11-12 |
Plexxikon Inc |
COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA
|
|
WO2008079909A1
(en)
|
2006-12-21 |
2008-07-03 |
Plexxikon, Inc. |
Pyrrolo [2,3-b] pyridines as kinase modulators
|
|
WO2008138755A2
(en)
|
2007-05-11 |
2008-11-20 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions for poorly soluble drugs
|
|
TW200908968A
(en)
|
2007-05-29 |
2009-03-01 |
Sgx Pharmaceuticals Inc |
Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators
|
|
EA021645B1
(ru)
|
2007-07-23 |
2015-08-31 |
Фарматен С.А. |
Твердая дозированная форма в виде таблетки и способ её приготовления
|
|
US20110003809A1
(en)
|
2008-02-29 |
2011-01-06 |
Array Biopharma Inc. |
Imidazo [4,5-b] pyridine derivatives used as raf inhibitors
|
|
JP2011513332A
(ja)
|
2008-02-29 |
2011-04-28 |
アレイ バイオファーマ、インコーポレイテッド |
癌の治療のためのｒａｆ阻害剤としてのｎ−（６−アミノピリジン−３−イル）−３−（スルホンアミド）ベンズアミド誘導体
|
|
WO2009111279A1
(en)
|
2008-02-29 |
2009-09-11 |
Array Biopharma Inc. |
Pyrazole [3, 4-b] pyridine raf inhibitors
|
|
MX2010009410A
(es)
|
2008-02-29 |
2010-11-30 |
Array Biopharma Inc |
Compuestos del inhibidor de raf y métodos de uso de los mismos.
|
|
UA103319C2
(en)
|
2008-05-06 |
2013-10-10 |
Глаксосмитклайн Ллк |
Thiazole- and oxazole-benzene sulfonamide compounds
|
|
TW201041888A
(en)
*
|
2009-05-06 |
2010-12-01 |
Plexxikon Inc |
Compounds and methods for kinase modulation, and indications therefor
|
|
TWI558702B
(zh)
|
2011-02-21 |
2016-11-21 |
普雷辛肯公司 |
醫藥活性物質的固態形式
|
|
US20130172375A1
(en)
|
2011-12-13 |
2013-07-04 |
Hoffmann-La Roche Inc. |
Pharmaceutical composition
|
