CN103432504A - Traditional Chinese medicine granules for treating children's constipation and preparation method thereof - Google Patents

Traditional Chinese medicine granules for treating children's constipation and preparation method thereof Download PDF

Info

Publication number
CN103432504A
CN103432504A CN2013103135735A CN201310313573A CN103432504A CN 103432504 A CN103432504 A CN 103432504A CN 2013103135735 A CN2013103135735 A CN 2013103135735A CN 201310313573 A CN201310313573 A CN 201310313573A CN 103432504 A CN103432504 A CN 103432504A
Authority
CN
China
Prior art keywords
parts
chinese medicine
medicine granules
fructus
traditional chinese
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2013103135735A
Other languages
Chinese (zh)
Other versions
CN103432504B (en
Inventor
俞洋
俞帮和
莫太平
张艳
王芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
Original Assignee
JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd filed Critical JIANGSU SUNAN PHARMACEUTICAL INDUSTRY Co Ltd
Priority to CN201310313573.5A priority Critical patent/CN103432504B/en
Publication of CN103432504A publication Critical patent/CN103432504A/en
Application granted granted Critical
Publication of CN103432504B publication Critical patent/CN103432504B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses traditional Chinese medicine granules for treating children's constipation. The traditional Chinese medicine granules comprises the raw materials in parts by weight: 6-12 parts of radix scrophulariae, 6-10 parts of fructustrichosanthis, 6-10 parts of ophiopogon japonicas, 6-10 parts of mulberry, 8-15 parts of chingma abutilon seeds, 5-8 parts of solanumlyratum, 6-10 parts of mallotusapelta, 5-10 parts of poriacocos, 5-10 parts of villous amomum fruit and 6-10 parts of licorice. The invention also discloses a preparation method of the traditional Chinese medicine granules. By employing a proper amount of radix scrophulariae, ophiopogon japonicas, mulberry, fructustrichosanthis and chingma abutilon seeds, the traditional Chinese medicine granules are capable of stimulating colonic motion; and by cooperated with solanumlyratum, mallotusapelta, poriacocos, villous amomum fruit and licorice, the traditional Chinese medicine granules are capable of clearing heat, detoxifying, and radically solving the focus of children's constipation; and the traditional Chinese medicine granules are none in toxic and side effect, safe and reliable.

Description

A kind of infantile constipation Chinese medicine granules and preparation method thereof for the treatment of
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of infantile constipation Chinese medicine granules and preparation method thereof for the treatment of.
Background technology
Constipation refers to the difficult defecation continued more than 2 weeks or 2 weeks, and the incidence rate of normal population infantile constipation is 0.3%~28%.Definition that it is generally acknowledged constipation should comprise following 4 aspects: (1) defecation frequency is less than 3 times/week, and severe patient can 2-4 all defecations 1 time; (2) defecation time extends, more than the each defecation time of severe patient is 30min; (3) the stool character changes, and feces is dry and hard; (4) difficult defecation or effort, have defecation to feel not to the utmost.Can be divided into functional constipation and organic constipation.Functional constipation in children (FC) is UCD, frequently-occurring disease, and sickness rate is 3%~5%, accounts for 25% of child's digestive tract outpatient service.FC not only shows and can affect gastrointestinal function the harm of human body, and can also have influence on child's memory and intelligent development, severe one also can cause the enuresis, fecal incontinence etc.
Because defecation frequency is few, feces is long in the enteral time of staying, after moisture content is fully absorbed, becomes stiff, discharges difficulty.Can be due to excrement piece compressing intestinal wall when serious, fecal ulcer, appear in the intestinal wall necrosis, the complication such as intestinal perforation, full peritonitis even can occur.
Existing treatment infantile constipation, cathartic commonly used, however a little less than children's's body constitution is grown up, cathartic can cause children's to dewater, impairing the spleen and stomach, and increase the probability of suffering from mechanical intestinal obstruction peritonitis, intestinal perforation, and life-time service, the side effect that children's's health is brought is obvious.
Summary of the invention
Goal of the invention: in order to overcome the deficiencies in the prior art, the invention provides a kind for the treatment of infantile constipation Chinese medicine granules safely, had no side effect.
Technical scheme: for achieving the above object, a kind of infantile constipation Chinese medicine granules for the treatment of provided by the invention, by following raw materials according weight portion proportioning, formed: 6~12 parts of Radix Scrophulariaes, 6~10 parts of Radix Ophiopogonis, 6~10 parts, Fructus Mori, 6~10 parts of Fructus Trichosanthis, 8~15 parts of Semen Abutilis, 5~8 parts of Herba Solani Lyratis, 6~10 parts of Folium Malloti Apeltaes, each 5~10 parts of Poria, Fructus Amomis, each 6~10 parts, Radix Glycyrrhizae.
The weight ratio of the optimization formula of preparation medicine of the present invention is: 8~12 parts of Radix Scrophulariaes, 8~10 parts of Fructus Trichosanthis, 6~10 parts of Radix Ophiopogonis, 6~10 parts, Fructus Mori, 10~15 parts of Semen Abutilis, 5~7 parts of Herba Solani Lyratis, 8~10 parts of Folium Malloti Apeltaes, each 8~10 parts of Poria, Fructus Amomis, each 8~10 parts, Radix Glycyrrhizae.
The weight ratio of the optimization formula of preparation medicine of the present invention is: 10 parts of described Radix Scrophulariaes, 7 parts of Radix Ophiopogonis, 9 parts, Fructus Mori, 8 parts of Fructus Trichosanthis, 12 parts of Semen Abutilis.
A kind of preparation method for the treatment of infantile constipation Chinese medicine granules claimed in claim 1, its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to the weight portion proportioning standby;
(2) decoct: weighed raw material is mixed, and is 1 ︰ 4~6 according to the weight ratio with water, decoct three times, and 1~1.5 hour for the first time, second and third time each 0.5~0.8 hour, collecting decoction, filter, standing;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1~1.2, puts to room temperature coolingly, adds ethanol and makes to reach 70% containing alcohol amount, stirs evenly, standing, gets supernatant, reclaims ethanol, is condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, granulation, drying, mix, and obtains.
Medically think food-intake few or dietary fiber Deficiency of Intake or water deficient, the stimulation of Colon Movement is reduced.A lot of children do not like to eat vegetable, like food higher fatty acid, hypercholesterolemia, and some heads of a family that lack health knowledge do not know again guiding, cause like this enterogastric peristalsis slow, dyspepsia, and food debris is excessively of a specified duration dead time in intestinal, thereby causes constipation.In food, how calcic also can cause constipation.In diet, protein content is too high makes stool be alkalescence, dry, and number of times reduces.In food, how calcic also can cause constipation, as more than people's milk as the milk calcic, thereby cow milk feeding is more than the chance of breast feeding generation constipation, and children's's body constitution fire of moxibustion is crossed the prosperous dry difficulty of defecation etc. that also can cause in addition.
Beneficial effect: the present invention adopts appropriate Radix Scrophulariae, Radix Ophiopogonis, Fructus Mori, Fructus Trichosanthis and Semen Abutili, can stimulate Colon Movement, coordinates Herba Solani Lyrati, Folium Malloti Apeltae, Poria, Fructus Amomi, Radix Glycyrrhizae conditioning body constitution are excessively prosperous, heat-clearing and toxic substances removing, fundamentally solve the focus of infantile constipation, have no side effect, safe and reliable.
The specific embodiment
Below in conjunction with embodiment, the present invention is further described.Following examples object is the child of age between 6 months to 3 years old.
Embodiment mono-:
A kind of infantile constipation Chinese medicine granules for the treatment of is comprised of following raw materials according weight portion proportioning: 6 parts of Radix Scrophulariaes, 10 parts of Radix Ophiopogonis, 10 parts, Fructus Mori, 10 parts of Fructus Trichosanthis, 15 parts of Semen Abutilis, 8 parts of Herba Solani Lyratis, 10 parts of Folium Malloti Apeltaes, each 10 parts of Poria, Fructus Amomis, each 10 parts, Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to the weight portion proportioning standby;
(2) decoct: weighed raw material is mixed, and is 1 ︰ 4 according to the weight ratio with water, decoct three times, and 1 hour for the first time, second and third time each 0.5 hour, collecting decoction, filter, standing;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1, puts to room temperature coolingly, adds ethanol and makes to reach 70% containing alcohol amount, stirs evenly, standing, gets supernatant, reclaims ethanol, is condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, granulation, drying, mix, and obtains.
Efficacy result: treatment group 78 examples: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 67 examples; (through all diseases alleviation of taking medicine) 7 examples take a turn for the better; Invalid (through drug administration symptom without changing) 4 examples.Total effective rate 94.87%, the shortest person for the treatment of time 7 days, the longest is 19 days.
Embodiment bis-:
A kind of infantile constipation Chinese medicine granules for the treatment of is comprised of following raw materials according weight portion proportioning: 12 parts of Radix Scrophulariaes, 6 parts of Radix Ophiopogonis, 6 parts, Fructus Mori, 6 parts of Fructus Trichosanthis, 8 parts of Semen Abutilis, 5 parts of Herba Solani Lyratis, 6 parts of Folium Malloti Apeltaes, each 5 parts of Poria, Fructus Amomis, each 6 parts, Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to the weight portion proportioning standby;
(2) decoct: weighed raw material is mixed, and is 1 ︰ 6 according to the weight ratio with water, decoct three times, and 1 hour for the first time, second and third time each 0.5 hour, collecting decoction, filter, standing;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.2, puts to room temperature coolingly, adds ethanol and makes to reach 70% containing alcohol amount, stirs evenly, standing, gets supernatant, reclaims ethanol, is condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, granulation, drying, mix, and obtains.
Efficacy result: treatment group 109 examples: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 98 examples; (through all diseases alleviation of taking medicine) 6 examples take a turn for the better; Invalid (through drug administration symptom without changing) 5 examples.Total effective rate 95.41%, the shortest person for the treatment of time 5 days, the longest is 26 days.
Embodiment tri-:
A kind of infantile constipation Chinese medicine granules for the treatment of is comprised of following raw materials according weight portion proportioning: 8 parts of Radix Scrophulariaes, 8 parts of Fructus Trichosanthis, 8 parts of Radix Ophiopogonis, 8 parts, Fructus Mori, 108 parts of Semen Abutilis, 7 parts of Herba Solani Lyratis, 8 parts of Folium Malloti Apeltaes, each 8 parts of Poria, Fructus Amomis, each 8 parts, Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to the weight portion proportioning standby;
(2) decoct: weighed raw material is mixed, and is 1 ︰ 5 according to the weight ratio with water, decoct three times, and 1 hour for the first time, second and third time each 0.5 hour, collecting decoction, filter, standing;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1, puts to room temperature coolingly, adds ethanol and makes to reach 70% containing alcohol amount, stirs evenly, standing, gets supernatant, reclaims ethanol, is condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, granulation, drying, mix, and obtains.
Efficacy result: treatment group 98 examples: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 90 examples; (through all diseases alleviation of taking medicine) 5 examples take a turn for the better; Invalid (through drug administration symptom without changing) 3 examples.Total effective rate 96.93%, the shortest person for the treatment of time 6 days, the longest is 23 days.
Embodiment tetra-:
A kind of infantile constipation Chinese medicine granules for the treatment of is comprised of following raw materials according weight portion proportioning: 10 parts of Radix Scrophulariaes, 7 parts of Radix Ophiopogonis, 9 parts, Fructus Mori, 8 parts of Fructus Trichosanthis, 12 parts of Semen Abutilis, 6 parts of Herba Solani Lyratis, 9 parts of Folium Malloti Apeltaes, each 9 parts of Poria, Fructus Amomis, each 9 parts, Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to the weight portion proportioning standby;
(2) decoct: weighed raw material is mixed, and is 1 ︰ 5 according to the weight ratio with water, decoct three times, and 1 hour for the first time, second and third time each 0.5 hour, collecting decoction, filter, standing;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1, puts to room temperature coolingly, adds ethanol and makes to reach 70% containing alcohol amount, stirs evenly, standing, gets supernatant, reclaims ethanol, is condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, granulation, drying, mix, and obtains.
Treatment group 98 examples: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 92 examples; (through all diseases alleviation of taking medicine) 4 examples take a turn for the better; Invalid (through drug administration symptom without changing) 2 examples.Total effective rate 97.96%, the shortest person for the treatment of time 4 days, the longest is 20 days.
The above is only the preferred embodiment of the present invention; be noted that for those skilled in the art; under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (4)

1. treat the infantile constipation Chinese medicine granules for one kind, it is characterized in that: by following raw materials according weight portion proportioning, formed: 6 ~ 12 parts of Radix Scrophulariaes, 6 ~ 10 parts of Fructus Trichosanthis, 6 ~ 10 parts of Radix Ophiopogonis, 6 ~ 10 parts, Fructus Mori, 8 ~ 15 parts of Semen Abutilis, 5 ~ 8 parts of Herba Solani Lyratis, 6 ~ 10 parts of Folium Malloti Apeltaes, each 5~10 parts of Poria, Fructus Amomis, each 6~10 parts, Radix Glycyrrhizae.
2. treatment infantile constipation Chinese medicine granules according to claim 1, it is characterized in that: by following raw materials according weight portion proportioning, formed: 8 ~ 12 parts of Radix Scrophulariaes, 8 ~ 10 parts of Fructus Trichosanthis, 6 ~ 10 parts of Radix Ophiopogonis, 6 ~ 10 parts, Fructus Mori, 10 ~ 15 parts of Semen Abutilis, 5 ~ 7 parts of Herba Solani Lyratis, 8 ~ 10 parts of Folium Malloti Apeltaes, each 8~10 parts of Poria, Fructus Amomis, each 8~10 parts, Radix Glycyrrhizae.
3. treatment infantile constipation Chinese medicine granules according to claim 1, is characterized in that: 10 parts of described Radix Scrophulariaes, 7 parts of Radix Ophiopogonis, 9 parts, Fructus Mori, 8 parts of Fructus Trichosanthis, 12 parts of Semen Abutilis.
4. the preparation method of a treatment infantile constipation Chinese medicine granules claimed in claim 1, it is characterized in that: its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to the weight portion proportioning standby;
(2) decoct: weighed raw material is mixed, and is 1 ︰ 4 ~ 6 according to the weight ratio with water, decoct three times, and 1 ~ 1.5 hour for the first time, second and third time each 0.5 ~ 0.8 hour, collecting decoction, filter, standing;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1 ~ 1.2, puts to room temperature coolingly, adds ethanol and makes to reach 70% containing alcohol amount, stirs evenly, standing, gets supernatant, reclaims ethanol, is condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, granulation, drying, mix, and obtains.
CN201310313573.5A 2013-07-24 2013-07-24 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof Expired - Fee Related CN103432504B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310313573.5A CN103432504B (en) 2013-07-24 2013-07-24 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310313573.5A CN103432504B (en) 2013-07-24 2013-07-24 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof

Publications (2)

Publication Number Publication Date
CN103432504A true CN103432504A (en) 2013-12-11
CN103432504B CN103432504B (en) 2015-05-20

Family

ID=49686288

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310313573.5A Expired - Fee Related CN103432504B (en) 2013-07-24 2013-07-24 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof

Country Status (1)

Country Link
CN (1) CN103432504B (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912472A (en) * 2010-08-13 2010-12-15 黄文珍 Chinese medicinal composition for treating habitual constipation and preparation method thereof
CN102078506A (en) * 2009-11-27 2011-06-01 赵莉 Traditional Chinese medicine composition for constipation
CN102106969A (en) * 2011-01-28 2011-06-29 秦军 Traditional Chinese medicine for treating deficiency constipation
CN102258705A (en) * 2010-05-28 2011-11-30 刘国昌 Chinese medicine composition for treating constipation
CN102357198A (en) * 2011-11-11 2012-02-22 赵君怡 Chinese medicinal composition for treating constipation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078506A (en) * 2009-11-27 2011-06-01 赵莉 Traditional Chinese medicine composition for constipation
CN102258705A (en) * 2010-05-28 2011-11-30 刘国昌 Chinese medicine composition for treating constipation
CN101912472A (en) * 2010-08-13 2010-12-15 黄文珍 Chinese medicinal composition for treating habitual constipation and preparation method thereof
CN102106969A (en) * 2011-01-28 2011-06-29 秦军 Traditional Chinese medicine for treating deficiency constipation
CN102357198A (en) * 2011-11-11 2012-02-22 赵君怡 Chinese medicinal composition for treating constipation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
甘淳等: "龚琼模治疗消化系统疾病经验", 《实用中西医结合临床》, vol. 2, no. 2, 30 April 2002 (2002-04-30), pages 36 - 37 *

Also Published As

Publication number Publication date
CN103432504B (en) 2015-05-20

Similar Documents

Publication Publication Date Title
CN104524110A (en) Traditional Chinese medicine composition with functions of tonifying spleen and clearing damp
CN103652361B (en) Feed for postpartum sow in lactation period of 1-20 days and preparation method thereof
CN101869626B (en) Chinese medicinal compound preparation private care liquid, and preparation and application thereof
CN102657794A (en) Traditional Chinese medicine for prevention and treatment of pullorum disease, preparation method thereof and feed
CN103623058A (en) Traditional Chinese medicine combination for preventing and treating bamboo rat gastroenteritis
CN102114200B (en) Pill with function of relaxing bowels and preparation method thereof
CN102743442B (en) Traditional Chinese medicine composition for improving gastrointestinal function and preparation method thereof
CN103432504B (en) Traditional Chinese medicine granules for treating children's constipation and preparation method thereof
CN107998359A (en) Control the Chinese medicine and preparation method of Gilt Uterus intimitis and Repeat breeding
CN104825753B (en) A kind of Chinese medicine composition for prevention newborn piglet diarrhea of being taken medicine by sow
CN1259962C (en) Bawei stomach strengthening and digestion promoting powder
CN106620474B (en) Stomach-nourishing health-care medicine and preparation method thereof
CN104587178A (en) Traditional Chinese medicine for treating postoperative difficult defecation
CN103656448A (en) Astringing and antidiarrheal composition and preparation method thereof
CN104524345A (en) Traditional Chinese medicine for treating infantile eczema
CN103690654A (en) Pharmaceutical composition for treating infantile diarrhea
CN103933189B (en) One is treated uremic Chinese medicine preparation
CN102872406A (en) Stone-eliminating tea for rapidly expelling stones in liver, gallbladder, kidney and conduit lumen
CN106729589A (en) Treat the Chinese medicine preparation and preparation method of transmissible gastroenteritis of swine
CN1453004A (en) Cathartic medicine and its prepn
CN102430004B (en) Traditional Chinese medicinal preparation for treating diarrhea
CN106361902A (en) Traditional Chinese medicine composition for preventing and treating livestock diarrhea and preparation method thereof
CN105031403A (en) Tea drink capable of eliminating faeces and enterotoxin and preparation method thereof
CN105902741A (en) Pharmaceutical composition for treating damp-heat diarrhea type calf diarrhea and preparation method thereof
CN104940332A (en) Fructo oligosaccharide composition for relaxing bowels and reducing flatulence and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150520

CF01 Termination of patent right due to non-payment of annual fee