CN102357198A - Chinese medicinal composition for treating constipation - Google Patents

Chinese medicinal composition for treating constipation Download PDF

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CN102357198A
CN102357198A CN2011103555802A CN201110355580A CN102357198A CN 102357198 A CN102357198 A CN 102357198A CN 2011103555802 A CN2011103555802 A CN 2011103555802A CN 201110355580 A CN201110355580 A CN 201110355580A CN 102357198 A CN102357198 A CN 102357198A
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constipation
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semen
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CN102357198B (en
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赵君怡
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Nantong Kwesw Biochemical Co ltd
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Abstract

The invention relates a Chinese medicinal composition for treating constipation. The Chinese medicinal composition is prepared from the following raw materials in part by weight: 20 parts of snakegourd fruit, 15 parts of astragalus, 18 parts of figwort root, 15 parts of dwarf lilyturf tuber, 10 parts of dandelion, 9 parts of tangerine peel, 8 parts of cassia seed, 5 parts of black sesame, 8 parts of platycladi seed, 8 parts of ligusticum wallichii, 10 parts of radish seed, 7 parts of polygonum multiflorum, 5 parts of medlar, 5 parts of liquorice, and 3 parts of polygonatum odoratum. Through clinical verification, the Chinese medicinal composition for treating constipation has the effect of treating constipation, and does not have any toxicity or harm to a human body or a side effect, can address both the symptoms and root causes, is low in cost, and easy to prepare, and has wide application prospect.

Description

A kind of Chinese medicine composition of treating constipation
Technical field
The invention belongs to the Chinese medicine technical field of pharmaceuticals, concrete, relate to a kind of Chinese medicine composition of treating constipation.
Background technology
Constipation is a kind of commonly encountered diseases, and clinical main performance stool is dry and hard for a long time, defecates once in many days, separates just difficulty misery at every turn, other disease of initiation easily of a specified duration.Along with the change of dietary structure and the interference of spiritual psychological factor, constipation has become one of key factor that influences modern quality of life.Yet at present clinical is that the disease or the notion of disease are relatively more chaotic about constipation; " constipation " is a kind of disease in the International Classification of Diseases; Domestic medical circle is to have multiple viewpoint on the disease or the problem of disease about " constipation ", and lack of uniform understanding is so that researcher or clinician are at a loss as to what to do.
Constipation is a difficulty and complicated clinical problem, along with the fast development of modern science and technology in recent years, and combines with the continuous of modern medicine; Medical circle has had significant progress to the understanding of constipation; Particularly with irradiation image learn a skill introduce the research of constipation after, produced qualitative leap, established the primary condition that constipation is sick and constipation possesses separately; Division is following: establish the sick primary condition of constipation: 1. have clear and definite sick position, sick position is at large intestine; 2. have clear and definite pathogeny, basic pathology is that the colon transmission is slowly with outlet obstructed; 3. have one group of distinctive symptom, sign and lab testing result, as: just time reduce, excrement matter is dry and hard, just meaning disappearance; X line barium agent radiography typical characteristic " gooseneck boom is levied ", " shelf is levied ", " intussusception in the rectal mucosa " wait other characteristics; 4. clear and definite diagnostic criteria and discrimination method are arranged; 5. can propose typing, classification, by stages, calibration etc.Establishing constipated primary condition has: 1. the functional constipation of some no organic disorder, and the patient lacks defecation physiology general knowledge, thereby has destroyed normal defecation physiology trained reflex, as: be late for defecation, just long term inhibition is anticipated; 2. the constipation that has clear and definite primary disease to occur together: (1) mental disorder constipation induced, like depression, psychosis, anorexia nervosa; (2) iatrogenic constipation is like codeine, morphine, antidepressant, anticholinergic agents that, chalybeate, braking etc.3. the constipation that causes of non-organic pathological changes, constipation in a year " course of disease " was less than 3 months.These all are symptomatic constipation, are prone to differentiate mutually with the constipation disease.In sum; Symptom with constipation; And can be through the organic disorder of iconography and relevant intestinal passage of laboratory diagnosis discovery or adjacent organs; Through regular Drug therapy invalid or unsatisfactory curative effect more than 3 months, or need long-term adopt that medicine, maneuver, apparatus help defecation can be diagnosed as the constipation disease.And primary disease is clear and definite; Often be secondary to the outer other diseases of intestinal passage; Or since medicine and the use of treatment other diseases apparatus caused; Do not have relevant organic disorder through iconography and laboratory diagnosis, constipation can be alleviated or eliminate after curing primary disease or removing above factor, can be diagnosed as constipation.In other words, the sick patient of constipation necessarily has the constipation symptom, but not every constipation can both be diagnosed as the constipation disease.In a single day constipation has caused the organic disorder of relevant intestinal passage or adjacent organs, just develops into the constipation disease.Certainly constipation is sick through efficacious therapy, relevant intestinal passage of check or adjacent organs do not have organic unusual again, still has constipation, and the constipation of this moment has been a symptom only just.
The pathogenesis of constipation: food is after digesting and assimilating; The remaining chyme residue that can not absorb once again drains into colon with enterokinesia by small intestinal; Colonic mucosa further absorbs moisture and electrolyte again, and feces generally progressively forms in transverse colon, transports at last to reach sigmoid colon, rectum.Rectal mucosa receives the mechanical irritation of the full expansion of feces; The sensigenous impulsion; Impulsion is neural through pelvic cavity, the waist sacral spinal cord imports cerebral cortex into, through nervus centrifugalis impulsion is reached rectum again, and rectum flesh is shunk; Anal sphincter is lax, and and then abdominal muscle and diaphram shrink simultaneously feces is excreted from anus.It below promptly is normal defecation reflex process.If all can cause constipation when obstacle appears in any one link of this defecation reflex process.Following factor all is the major reason that constipation takes place: 1. food or the hypohydration taken in, and the chyme residue of enteral or the amount of feces are also lacked, be not enough to stimulate the normal creepage of gastrointestinal functions of colon; 2. the wriggle weakness of intestinal or intestinal muscle tone lower; 3. enteric cavity has narrow or blocks existence, and normal enterokinesia is obstructed, and causes the feces can not the row of descending, for example intestinal obstruction or proportion of cancer of left side of colon.4. when any link has obstacle or pathological changes in the defecation reflex process all constipation can take place, the decreased sensation of rectal mucosa mechanical irritation for example, pelvic cavity is neural, waist sacral spinal cord neuropathy, and sphincterismus, abdominal muscle and diaphram contractile motion weaken etc.
The argumentation of the relevant constipation of the traditional Chinese medical science is shown in Huangdi's Internal Classics the earliest, and set forth the disease of constipation and decreased position, the cause of disease, relevant internal organs and clinical symptoms, be a kind of disease but do not spell out it.All there is performance in back physicians from a family for generations family to the argumentation of aspects such as the symptom of constipation, diagnosis, dialectical, treatment, and what have discusses it as a kind of independently disease, and what have only is used as a symptom to it, lacks unified understanding so far.Think in the existing textbooks of traditional Chinese medical science universities and colleges " Chinese Internal Medicine ": " constipation is meant because the large intestine conduction is not normal, causes constipation, the defecation cycle stretch-out; Or the cycle is not long, but excrement matter is dry and hard, and it is difficult to discharge; Or excrement matter is not hard, though just meaning, just and not smooth disease are arranged ".Infer that in view of the above the constipation that this piece discussed mainly is that the notion with symptom occurs.But next this piece of writing is divided into constipation of excess type (accumulated heat in gastrointestinal tract, depression and stagnation of QI, YIN-cold stagnate) and two big types of seven pattern of syndrome of constipation due to insufficiency (deficiency of vital energy, blood deficiency, the deficiency of YIN, yang deficiency) with constipation again; More detailed differentiation of symptoms and signs for classification of syndrome occurred, " constipation " discussed here obviously has been disease rather than " symptom ".In the argumentation of a same piece of writing, sick notion with disease is still fuzzy.The China people national standard " tcm clinical practice diagnosis and treatment term disease part " that benefits the nation is is altogether compiled and edited 930 of disease terms (not comprising Bone injury disease) altogether, and 49 of symptomatic terms with clear and definite the belonging in the symptomatic term of constipation, think that constipation is a kind of symptom.And the traditional Chinese medical science monograph of recent publication is listed in the status equal with other anal and intestinal diseases with chapters and sections independently with constipation; And launch argumentation from aspects such as etiology and pathology, clinical manifestation, lab testing, diagnosis and discriminating, treatment and prognosis as independently sick a kind, it is thus clear that head and shoulders above the category of symptom.At present, the traditional Chinese medical science is divided into following four types with constipation: 1. the intestines and stomach dryness-heat type: pungent thick the hiding of surfeit, and cross the article of obeying temperature compensation and wait and can cause the bright the moon of the excess of YANG; After the calentura, waste heat is reluctant to leave the intestines and stomach, consumption impairment of body fluid liquid; Or the damp invasion of lower energizer large intestine, make intestinal scorching, impairment of body fluid and constipation, this constipation is called functional constipation again.2. depression and stagnation of QI type: feelings will is not relaxed, sorrow is pondered over, sitting is moving less, prolonged illness bed etc. causes depression and stagnation of QI, causes and stops in large intestine conduction dereliction of duty, the waste matter, form constipated, promptly so-called " stagnate in the gas and thing is not all right ".3. type of deficiency of both blood and body fluid: prolonged illness, puerperal, old asthenia, QI and blood deficiency; Taste internal injury, amount of drinking water are few, and the change source is not enough, too diaphoresis in the disease, rush down down impairment of YIN etc.The deficiency of vital energy then large intestine is passed on unablely, and blood deficiency and depleted fluid then large intestine moisten to lose is supported, and it is withered that intestinal is done, just go involved and abstruse, so be called constipation due to insufficiency.4. yang deficiency of spleen and stomache: year high prolonged illness, kidney-yang deficiency, yang-energy do not transport then that YIN pathogen condenses; Or have the spleen YANG deficiency, and sent an expedition against by cold, decline and cause the spleen kidney yang, Wen Zhao haves no right then QI stagnated by cold, and intestinal transmits unable, and difficulty in defecation is called constipation due to accumulation of pathogenic cold.
The medicine of prior art treatment constipation is more; In, Western medicine has, the Western medicine side effect is big, Chinese medicine belongs to a bit cures the symptoms, not the disease; Some interrupts using owing to uncertain therapeutic efficacy is fixed in application process; In addition, also there is the technical problem of specific aim difference, do not find to have the specific drug of special for treating constipation due to insufficiency type constipation at present as yet.
Summary of the invention
The purpose of this invention is to provide a kind of treating both the principal and secondary aspects of a disease, have no side effect, safe ready, cheap pure traditional Chinese compound medicine.
The application inventor combines secret prescription handed down in the family from generation to generation according to forefathers' experience and the medical practice of oneself more than ten years, through the research to Chinese medicine, and combines dialectical demonstration; In many ways collect the length of many families, seek therapeutic regimen, from motherland's medical treasure-house; Filter out nourishing blood to promote the production of body fluid, the natural Chinese medicine of loosening bowel to relieve constipation is by the theory of Chinese medical science prescription; Skim the cream off milk, make its performance heat clearing away, Bao Jin, nourish blood, lung heat clearing, the effect of moisturizing laxation, adopt the natural Chinese medicines raw material; Be mixed with the Chinese medicine composition of treatment constipation of the present invention meticulously in conjunction with traditional lunar physics technique, constipation had the effect of rapid healing.
For realizing above-mentioned purpose, the technical scheme that the present invention adopts is following:
A kind of Chinese medicine composition of treating constipation, it is got by following weight proportioning feedstock production,
20 parts of Fructus Trichosanthis, 15 parts of the Radixs Astragali, 18 parts of Radix Scrophulariaes, 15 parts of Radix Ophiopogonis
10 parts of Herba Taraxacis, 9 parts of Pericarpium Citri Reticulataes, 8 parts of Semen Cassiaes, 5 parts of Semen Sesami Nigrums
8 parts of Semen Platycladi, 8 parts of Rhizoma Chuanxiongs, 10 parts of Semen Raphanis, 7 parts of Radix Polygoni Multiflori
5 parts of Fructus Lycii, 5 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Polygonati Odorati.
Its preparation of pharmaceutical composition of the present invention and instructions of taking are: get crude drug (proportioning unit: the restrain) mix homogeneously of above-mentioned parts by weight, be decocted in water for oral dose, potion divided sooner or later and took a course of treatment two Mondays twice every day.
The Chinese medicine composition of treatment constipation of the present invention also can be made into capsule, and its method is to get the crude drug mix homogeneously of above-mentioned mass fraction, the adding clear water; Fry in shallow oil 3 times, 3 decocting liquids are merged, filter, be condensed into the clear paste that density is 1.1-1.2g/ml; After the drying, be ground into 100-120 purpose medicated powder, in incapsulating, sterilization makes the capsule product; Each oral 3-5 grain, three times on the one, a course of treatment two Mondays.
The animal pharmacodynamics test of medicine of the present invention:
Utilization constipation model carries out the experiment of normal mouse defecation; Intestinal contents advances experiment (small intestine movement of mice propelling method, atropine load mice bowel movement obstacle model, normal rat large intestine propelling method); Intestinal moisture absorption experiment (experiment of normal mouse intestinal moisture absorption, the experiment of rat intestinal moisture), the Cavia porcellus intestinal tube smooth muscle experiment etc. of exsomatizing are observed and are tried composition soft capsule to the preventive and therapeutic effect of constipation model and in body and intestine in vitro, to the influence of intestine and small intestine moisture absorption.Result of the test shows:
1, mice with constipation is had the cathartic defecating feces excretion: being tried thing has stronger functions of loosening bowel relieving constipation to the uninteresting knot in Tianjin, excess-heat dryness accumulated in the stomach and intestine and non-specific mice with constipation; Can shorten defecation time for the first time to some extent; Increase the mice feces volume; And can soften stool, increase the defecation sum and increase feces water content (p<0.05, p<0.01).Above-mentioned constipation model mice is tried, and institute's bowel movement is main with soft stool and loose stool behind the thing, and feces is shaped, soft expanding in the majority.
2, normal mouse is had the unimpeded just effect of profit: tried thing and can obviously shorten behind the administration 1h normal mouse defecation time for the first time, defecation grain number increases, and the feces water content increases (p<0.05, p<0.01).Normal mouse is tried, and institute's bowel movement is main with soft stool and loose stool behind the thing, and feces is shaped, soft expanding in the majority.It is most for being shaped or shapeless, thick loose stools to be tried object height dose groups mice stool, and minority is scattered paste shape or like the loose stool of water liquid.
3, reduce the intestinal absorption of water: tried thing and can suppress normal sized Mus moisture absorption, increase the intestinal tube water content, play the effect (p<0.05, p<0.01) of softening stool.
Its use of Chinese medicine composition result that the present invention treats constipation shows that following advantage is arranged:
1, the present invention selects the natural Chinese medicines raw material for use, and each component meets pharmaceutical control law regulation, utilizes the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and constipation is had the effect of healing, does not have chemical sweeting agent, and is harmless to human non-toxic.
2, treating both the principal and secondary aspects of a disease of the present invention, have no side effect, cheap, simple for production.
Clinical data:
150 constipation patients of picked at random, wherein the man is 81,69 of woman, age 25-71 year, average 45 years old; Average course of disease 3 years.Symptom: defecation time prolongs, and 3 days with the last time, the feces dry, hard.Through taking Chinese medicine Chinese medicine composition of the present invention after 3 courses of treatment, 117 people cure (2 days with interior defecation once, and just matter is changeed profit, and unobstructed when separating, short-term does not have recurrence); 24 people improvement (just matter was changeed profit with interior defecation in 3 days, and it is smooth that defecation is owed); 9 people are not healed (symptom does not have improvement), and total effective rate is 94%.
The specific embodiment
Embodiment 1:
A kind of Chinese medicine composition of treating constipation, it is got by following weight proportioning feedstock production,
20 parts of Fructus Trichosanthis, 15 parts of the Radixs Astragali, 18 parts of Radix Scrophulariaes, 15 parts of Radix Ophiopogonis
10 parts of Herba Taraxacis, 9 parts of Pericarpium Citri Reticulataes, 8 parts of Semen Cassiaes, 5 parts of Semen Sesami Nigrums
8 parts of Semen Platycladi, 8 parts of Rhizoma Chuanxiongs, 10 parts of Semen Raphanis, 7 parts of Radix Polygoni Multiflori
5 parts of Fructus Lycii, 5 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Polygonati Odorati.
Get crude drug (proportioning unit: the restrain) mix homogeneously of above-mentioned parts by weight, be decocted in water for oral dose, potion divided sooner or later and took for twice every day;
Embodiment 2:
A kind of Chinese medicine composition of treating constipation, it is got by following weight proportioning feedstock production,
20 parts of Fructus Trichosanthis, 15 parts of the Radixs Astragali, 18 parts of Radix Scrophulariaes, 15 parts of Radix Ophiopogonis
10 parts of Herba Taraxacis, 9 parts of Pericarpium Citri Reticulataes, 8 parts of Semen Cassiaes, 5 parts of Semen Sesami Nigrums
8 parts of Semen Platycladi, 8 parts of Rhizoma Chuanxiongs, 10 parts of Semen Raphanis, 7 parts of Radix Polygoni Multiflori
5 parts of Fructus Lycii, 5 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Polygonati Odorati.
Get the crude drug mix homogeneously of above-mentioned mass fraction, add clear water, fry in shallow oil 3 times, 3 decocting liquids are merged; Filter, be condensed into the clear paste that density is 1.1-1.2g/ml, after 50-60 ℃ of drying; Be ground into 100-120 purpose medicated powder, in incapsulating, sterilization makes the capsule product.
Embodiment 3
Clinical exemplary embodiments
1 money, the woman, 33 years old, since producing, inappetence, physical weakness always; The constipation 5 years of being hard and dry, stool on the six to seven once, each stool is sheep stool appearance, stomachache sometimes, abdominal distention; Conscious feverish sensation in the palms and soles, little Huang of urinating, once all invalid with cathartic, so the diagnosis and treatment of coming.Inspection: shallow complexion, thin.The little Huang of pale tongue tongue, the pulse condition imaginary number; X line barium agent radiography typical characteristic " gooseneck boom is levied ".Dialectical: dry up in blood deficiency Tianjin, conduction mistake department.Take the Chinese medicinal composition capsules of embodiment 2 preparations, after two courses of treatment, patient's dysphoria with feverish sensation in the chest palms and soles moves back, and stool is lubricated unobstructed, and stomachache is ended, and appetite is promoted.The pale tongue tongue is few, and the clothes course of treatment and heal of continuing, X line barium agent radiography is no abnormal, recurs so far again.
2 what certain woman 52 years old, the readme physical weakness, constipation is obstructed, feces is dry, involved and abstruse being difficult to resolve, constipation 7 years, on average stool is once weekly; Each stool is sheep stool appearance, little Huang of urinating, and armrest helps just sometimes; Suffer from abdominal pain during prescription on individual diagnosis, defecate and do not go in seven days, straining at stool causes the hematochezia of defecating; Anus has a kind of sensation of tearing, and anus twinge in two days greatly after an action of the bowels at every turn is very painful.Red tongue, there is slight crack the centre, thick, yellow and greasy fur, the pulse condition stringy and thready pulse is puckery, one expiration and inspiration five to.Be diagnosed as: deficiency of both QI and YIN, body fluid loses empty.Take the Chinese medicine composition of embodiment 1 described treatment constipation, after three courses of treatment, patient's dysphoria with feverish sensation in the chest palms and soles moves back, and stool is lubricated unobstructed, and stomachache is ended, and appetite is promoted.The pale tongue tongue is few, and the clothes course of treatment and heal of continuing, X line barium agent radiography is no abnormal, and transference cure is fully recovered.Followed up a case by regular visits to 1 year, so far not recurrence again.
The man of 3 Qin 47 years old, readme physical weakness, unable, inappetence, the constipation 8 years of being hard and dry; An average week defecates once, and each stool is sheep stool appearance, suffers from abdominal pain abdominal distention sometimes; Feverish sensation in the palms and soles, little Huang of urinating once used " Radix Et Rhizoma Rhei " and Western medicine cathartics such as " phenolphthaleins " all invalid, so the diagnosis and treatment of coming.Inspection: shallow complexion, thin.The little Huang of pale tongue tongue, the pulse condition imaginary number; X line barium agent radiography typical characteristic " intussusception in the rectal mucosa ".Dialectical: dry up in blood deficiency Tianjin, conduction mistake department.The rule of treatment: nourishing blood to promote the production of body fluid, loosening bowel to relieve constipation.Take the Chinese medicine composition of embodiment 1 described treatment constipation, after three courses of treatment, further consultation: patient's dysphoria with feverish sensation in the chest palms and soles moves back, and stool is lubricated unobstructed, and stomachache is ended, and appetite is promoted.The pale tongue tongue is few, and the clothes course of treatment and heal of continuing, X line barium agent radiography is no abnormal, recurs so far again.
Above-mentioned each Chinese medicine that the present invention adopts is made compatibility mutually, can bring into play its collaborative effect of curing the disease, and has drug effect between each composition of used raw material of Chinese medicine and is interweaved and mutually promotes and coordinate usefulness; Through clinical verification, constipation there is good therapeutic effect, in the medical practice in nearly ten years of the applicant; The case number of curing is numerous; All obtain good effect, and with low cost, alleviate patient's burden.
The Chinese medicine composition of the application's treatment constipation is with low cost, evident in efficacy, has broad application prospects.

Claims (4)

1. Chinese medicine composition of treating constipation, it is got by following feedstock production,
Fructus Trichosanthis, the Radix Astragali, Radix Scrophulariae, Radix Ophiopogonis, Herba Taraxaci, Pericarpium Citri Reticulatae, Semen Cassiae, Semen Sesami Nigrum, Semen Platycladi, Rhizoma Chuanxiong, Semen Raphani, Radix Polygoni Multiflori, Fructus Lycii, Radix Glycyrrhizae, Rhizoma Polygonati Odorati.
2. the described Chinese medicine composition of claim 1, it is got by following weight proportioning feedstock production,
20 parts of Fructus Trichosanthis, 15 parts of the Radixs Astragali, 18 parts of Radix Scrophulariaes, 15 parts of Radix Ophiopogonis
10 parts of Herba Taraxacis, 9 parts of Pericarpium Citri Reticulataes, 8 parts of Semen Cassiaes, 5 parts of Semen Sesami Nigrums
8 parts of Semen Platycladi, 8 parts of Rhizoma Chuanxiongs, 10 parts of Semen Raphanis, 7 parts of Radix Polygoni Multiflori
5 parts of Fructus Lycii, 5 parts in Radix Glycyrrhizae, 3 parts of Rhizoma Polygonati Odorati.
Claim 1 or 2 said Chinese medicine compositions method for preparing, it is characterized in that, get the crude drug mix homogeneously by the quality proportioning, add clear water; Fry in shallow oil 3 times, 3 decocting liquids are merged, filter, be condensed into the clear paste that density is 1.2g/ml; After the drying, be ground into 120 purpose medicated powder, incapsulate.
4. claim 1 or 2 described Chinese medicine compositions are treated the purposes in the constipation medicine in preparation.
CN 201110355580 2011-11-11 2011-11-11 Chinese medicinal composition for treating constipation Expired - Fee Related CN102357198B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600358A (en) * 2012-03-31 2012-07-25 广州白云山和记黄埔中药有限公司 Traditional Chinese laxative medicine and product thereof
CN103053905A (en) * 2013-01-16 2013-04-24 无限极(中国)有限公司 Health-care food with constipation improvement function
CN103432504A (en) * 2013-07-24 2013-12-11 江苏苏南药业实业有限公司 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof
CN104225006A (en) * 2014-09-03 2014-12-24 上海焦点生物技术有限公司 Traditional Chinese medicine composition capable of invigorating Qi and relaxing bowels
CN104997942A (en) * 2015-08-14 2015-10-28 胡淑彦 Traditional Chinese medicine for treating children's functional constipation caused by dyspepsia and internal heat
CN105748958A (en) * 2016-04-08 2016-07-13 朱颖 Traditional Chinese medicine composition for treating bowel dysfunction

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600358A (en) * 2012-03-31 2012-07-25 广州白云山和记黄埔中药有限公司 Traditional Chinese laxative medicine and product thereof
CN102600358B (en) * 2012-03-31 2014-03-26 广州白云山和记黄埔中药有限公司 Traditional Chinese laxative medicine and product thereof
CN103053905A (en) * 2013-01-16 2013-04-24 无限极(中国)有限公司 Health-care food with constipation improvement function
CN103053905B (en) * 2013-01-16 2014-01-29 无限极(中国)有限公司 Health-care food with constipation improvement function
CN103432504A (en) * 2013-07-24 2013-12-11 江苏苏南药业实业有限公司 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof
CN103432504B (en) * 2013-07-24 2015-05-20 江苏苏南药业实业有限公司 Traditional Chinese medicine granules for treating children's constipation and preparation method thereof
CN104225006A (en) * 2014-09-03 2014-12-24 上海焦点生物技术有限公司 Traditional Chinese medicine composition capable of invigorating Qi and relaxing bowels
CN104997942A (en) * 2015-08-14 2015-10-28 胡淑彦 Traditional Chinese medicine for treating children's functional constipation caused by dyspepsia and internal heat
CN105748958A (en) * 2016-04-08 2016-07-13 朱颖 Traditional Chinese medicine composition for treating bowel dysfunction

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