CN103432504B - Traditional Chinese medicine granules for treating children's constipation and preparation method thereof - Google Patents
Traditional Chinese medicine granules for treating children's constipation and preparation method thereof Download PDFInfo
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- CN103432504B CN103432504B CN201310313573.5A CN201310313573A CN103432504B CN 103432504 B CN103432504 B CN 103432504B CN 201310313573 A CN201310313573 A CN 201310313573A CN 103432504 B CN103432504 B CN 103432504B
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Abstract
The invention discloses traditional Chinese medicine granules for treating children's constipation. The traditional Chinese medicine granules comprises the raw materials in parts by weight: 6-12 parts of radix scrophulariae, 6-10 parts of fructustrichosanthis, 6-10 parts of ophiopogon japonicas, 6-10 parts of mulberry, 8-15 parts of chingma abutilon seeds, 5-8 parts of solanumlyratum, 6-10 parts of mallotusapelta, 5-10 parts of poriacocos, 5-10 parts of villous amomum fruit and 6-10 parts of licorice. The invention also discloses a preparation method of the traditional Chinese medicine granules. By employing a proper amount of radix scrophulariae, ophiopogon japonicas, mulberry, fructustrichosanthis and chingma abutilon seeds, the traditional Chinese medicine granules are capable of stimulating colonic motion; and by cooperated with solanumlyratum, mallotusapelta, poriacocos, villous amomum fruit and licorice, the traditional Chinese medicine granules are capable of clearing heat, detoxifying, and radically solving the focus of children's constipation; and the traditional Chinese medicine granules are none in toxic and side effect, safe and reliable.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to one and treat infantile constipation Chinese medicine granules and preparation method thereof.
Background technology
Constipation refers to the difficult defecation of lasting more than 2 weeks or 2 weeks, and the incidence rate of normal population infantile constipation is 0.3% ~ 28%.It is generally acknowledged that the definition of constipation should comprise following 4 aspects: (1) defecation frequency is less than 3 times/week, severe patient can 2-4 all defecations 1 time; (2) defecation time extends, and each defecation time of severe patient is more than 30min; (3) stool changes, and feces is dry and hard; (4) difficult defecation or effort, has defecation to feel not to the utmost.Functional constipation and organic constipation can be divided into.Functional constipation in children (FC) is UCD, frequently-occurring disease, and sickness rate is 3% ~ 5%, accounts for 25% of the outpatient service of child's digestive tract.FC not only shows can affect gastrointestinal function to the harm of human body, and can also have influence on memory and the intelligent development of child, severe one also can cause the enuresis, fecal incontinence etc.
Because defecation frequency is few, feces is long in the enteral time of staying, becomes stiff after moisture content is fully absorbed, and discharges difficulty.Can due to excrement block compressing intestinal wall time serious, intestinal wall is downright bad, occurs fecal ulcer, even can occur the complication such as intestinal perforation, full peritonitis.
Existing treatment infantile constipation, conventional cathartic, but child physical endowment is comparatively grown up weak, cathartic can cause children's to dewater, impairing the spleen and stomach, and increases the probability suffering from mechanical intestinal obstruction peritonitis, intestinal perforation, and life-time service, the side effect brought the health of children's is obvious.
Summary of the invention
Goal of the invention: in order to overcome the deficiencies in the prior art, the invention provides a kind for the treatment of infantile constipation Chinese medicine granules safely, to have no side effect.
Technical scheme: for achieving the above object, one provided by the invention treats infantile constipation Chinese medicine granules, be made up of following raw materials according weight: Radix Scrophulariae 6 ~ 12 parts, Radix Ophiopogonis 6 ~ 10 parts, 6 ~ 10 parts, Fructus Mori, Fructus Trichosanthis 6 ~ 10 parts, Semen Abutili 8 ~ 15 parts, Herba Solani Lyrati 5 ~ 8 parts, Folium Malloti Apeltae 6 ~ 10 parts, each 5 ~ 10 parts of Poria, Fructus Amomi, each 6 ~ 10 parts of Radix Glycyrrhizae.
The weight ratio preparing the optimization formula of medicine of the present invention is: Radix Scrophulariae 8 ~ 12 parts, Fructus Trichosanthis 8 ~ 10 parts, Radix Ophiopogonis 6 ~ 10 parts, 6 ~ 10 parts, Fructus Mori, Semen Abutili 10 ~ 15 parts, Herba Solani Lyrati 5 ~ 7 parts, Folium Malloti Apeltae 8 ~ 10 parts, each 8 ~ 10 parts of Poria, Fructus Amomi, each 8 ~ 10 parts of Radix Glycyrrhizae.
The weight ratio preparing the optimization formula of medicine of the present invention is: described Radix Scrophulariae 10 parts, Radix Ophiopogonis 7 parts, 9 parts, Fructus Mori, Fructus Trichosanthis 8 parts, Semen Abutili 12 parts.
A preparation method for treatment infantile constipation Chinese medicine granules according to claim 1, its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to weight for subsequent use;
(2) decoct: mixed by weighed raw material, be 1 ︰ 4 ~ 6, decoct three times according to the weight ratio with water, 1 ~ 1.5 hour first time, second and third time each 0.5 ~ 0.8 hour, collecting decoction, filters, and leaves standstill;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1 ~ 1.2, puts to room temperature cooling, adds ethanol and make alcohol content reach 70%, stir evenly, leave standstill, get supernatant, reclaim ethanol, be condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, make granule, dry, mixing, to obtain final product.
Medically think and the few or dietary fiber Deficiency of Intake of food-intake or water deficient the stimulation of Colon Movement is reduced.A lot of child does not like to eat vegetable, likes higher fatty acid, the food of hypercholesterolemia, and some heads of a family lacking health knowledges do not know again to guide, and cause enterogastric peristalsis slow like this, dyspepsia, food debris is excessively of a specified duration for dead time in intestinal, thus causes constipation.In food, calcic is many also can cause constipation.In diet, protein content is too high makes stool be alkaline, dry, and number of times reduces.In food, calcic is many also can cause constipation, as more than people's milk in milk calcic, and thus cow milk feeding is more than the chance of breast feeding generation constipation, and child physical endowment fire of moxibustion is crossed and prosperously also can be caused the dry difficulty of defecation etc. in addition.
Beneficial effect: the present invention adopts appropriate Radix Scrophulariae, Radix Ophiopogonis, Fructus Mori, Fructus Trichosanthis and Semen Abutili, can stimulate Colon Movement, coordinates Herba Solani Lyrati, Folium Malloti Apeltae, Poria, Fructus Amomi, Radix Glycyrrhizae conditioning body constitution excessively prosperous, heat-clearing and toxic substances removing, fundamentally solve the focus of infantile constipation, have no side effect, safe and reliable.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described.Following examples object is the child of age between 6 months to 3 years old.
Embodiment one:
One treats infantile constipation Chinese medicine granules, is made up of following raw materials according weight: Radix Scrophulariae 6 parts, Radix Ophiopogonis 10 parts, 10 parts, Fructus Mori, Fructus Trichosanthis 10 parts, Semen Abutili 15 parts, Herba Solani Lyrati 8 parts, Folium Malloti Apeltae 10 parts, each 10 parts of Poria, Fructus Amomi, each 10 parts of Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to weight for subsequent use;
(2) decoct: mixed by weighed raw material, be 1 ︰ 4, decoct three times according to the weight ratio with water, 1 hour first time, second and third time each 0.5 hour, collecting decoction, filters, and leaves standstill;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1, puts to room temperature cooling, adds ethanol and make alcohol content reach 70%, stir evenly, leave standstill, get supernatant, reclaim ethanol, be condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, make granule, dry, mixing, to obtain final product.
Efficacy result: treatment group 78 example: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 67 examples; (through all diseases alleviation of taking medicine) 7 that take a turn for the better is routine; Invalid (through drug administration symptom without change) 4 is routine.Total effective rate 94.87%, treatment time the shortest person 7 days, the longest is 19 days.
Embodiment two:
One treats infantile constipation Chinese medicine granules, is made up of following raw materials according weight: Radix Scrophulariae 12 parts, Radix Ophiopogonis 6 parts, 6 parts, Fructus Mori, Fructus Trichosanthis 6 parts, Semen Abutili 8 parts, Herba Solani Lyrati 5 parts, Folium Malloti Apeltae 6 parts, each 5 parts of Poria, Fructus Amomi, each 6 parts of Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to weight for subsequent use;
(2) decoct: mixed by weighed raw material, be 1 ︰ 6, decoct three times according to the weight ratio with water, 1 hour first time, second and third time each 0.5 hour, collecting decoction, filters, and leaves standstill;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.2, puts to room temperature cooling, adds ethanol and make alcohol content reach 70%, stir evenly, leave standstill, get supernatant, reclaim ethanol, be condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, make granule, dry, mixing, to obtain final product.
Efficacy result: treatment group 109 example: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 98 examples; (through all diseases alleviation of taking medicine) 6 that take a turn for the better is routine; Invalid (through drug administration symptom without change) 5 is routine.Total effective rate 95.41%, treatment time the shortest person 5 days, the longest is 26 days.
Embodiment three:
One treats infantile constipation Chinese medicine granules, is made up of following raw materials according weight: Radix Scrophulariae 8 parts, Fructus Trichosanthis 8 parts, Radix Ophiopogonis 8 parts, 8 parts, Fructus Mori, Semen Abutili 108 parts, Herba Solani Lyrati 7 parts, Folium Malloti Apeltae 8 parts, each 8 parts of Poria, Fructus Amomi, each 8 parts of Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to weight for subsequent use;
(2) decoct: mixed by weighed raw material, be 1 ︰ 5, decoct three times according to the weight ratio with water, 1 hour first time, second and third time each 0.5 hour, collecting decoction, filters, and leaves standstill;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1, puts to room temperature cooling, adds ethanol and make alcohol content reach 70%, stir evenly, leave standstill, get supernatant, reclaim ethanol, be condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, make granule, dry, mixing, to obtain final product.
Efficacy result: treatment group 98 example: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 90 examples; (through all diseases alleviation of taking medicine) 5 that take a turn for the better is routine; Invalid (through drug administration symptom without change) 3 is routine.Total effective rate 96.93%, treatment time the shortest person 6 days, the longest is 23 days.
Embodiment four:
One treats infantile constipation Chinese medicine granules, is made up of following raw materials according weight: Radix Scrophulariae 10 parts, Radix Ophiopogonis 7 parts, 9 parts, Fructus Mori, Fructus Trichosanthis 8 parts, Semen Abutili 12 parts, Herba Solani Lyrati 6 parts, Folium Malloti Apeltae 9 parts, each 9 parts of Poria, Fructus Amomi, each 9 parts of Radix Glycyrrhizae.
Its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to weight for subsequent use;
(2) decoct: mixed by weighed raw material, be 1 ︰ 5, decoct three times according to the weight ratio with water, 1 hour first time, second and third time each 0.5 hour, collecting decoction, filters, and leaves standstill;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1, puts to room temperature cooling, adds ethanol and make alcohol content reach 70%, stir evenly, leave standstill, get supernatant, reclaim ethanol, be condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, make granule, dry, mixing, to obtain final product.
Treatment group 98 example: cure (through all diseases disappearance of taking medicine, relieving constipation is normal) 92 examples; (through all diseases alleviation of taking medicine) 4 that take a turn for the better is routine; Invalid (through drug administration symptom without change) 2 is routine.Total effective rate 97.96%, treatment time the shortest person 4 days, the longest is 20 days.
The above is only the preferred embodiment of the present invention; be noted that for those skilled in the art; under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (4)
1. a treatment infantile constipation Chinese medicine granules, it is characterized in that: be made up of following raw materials according weight: Radix Scrophulariae 6 ~ 12 parts, Fructus Trichosanthis 6 ~ 10 parts, Radix Ophiopogonis 6 ~ 10 parts, 6 ~ 10 parts, Fructus Mori, Semen Abutili 8 ~ 15 parts, Herba Solani Lyrati 5 ~ 8 parts, Folium Malloti Apeltae 6 ~ 10 parts, each 5 ~ 10 parts of Poria, Fructus Amomi, 6 ~ 10 parts, Radix Glycyrrhizae.
2. treatment infantile constipation Chinese medicine granules according to claim 1, it is characterized in that: be made up of following raw materials according weight: Radix Scrophulariae 8 ~ 12 parts, Fructus Trichosanthis 8 ~ 10 parts, Radix Ophiopogonis 6 ~ 10 parts, 6 ~ 10 parts, Fructus Mori, Semen Abutili 10 ~ 15 parts, Herba Solani Lyrati 5 ~ 7 parts, Folium Malloti Apeltae 8 ~ 10 parts, each 8 ~ 10 parts of Poria, Fructus Amomi, 8 ~ 10 parts, Radix Glycyrrhizae.
3. treatment infantile constipation Chinese medicine granules according to claim 1, is characterized in that: described Radix Scrophulariae 10 parts, Radix Ophiopogonis 7 parts, 9 parts, Fructus Mori, Fructus Trichosanthis 8 parts, Semen Abutili 12 parts.
4. a preparation method for treatment infantile constipation Chinese medicine granules according to claim 1, is characterized in that: its preparation process comprises as follows:
(1) weigh: take corresponding raw material components according to weight for subsequent use;
(2) decoct: mixed by weighed raw material, be 1:4 ~ 6, decoct three times according to the weight ratio with water, 1 ~ 1.5 hour first time, second and third time each 0.5 ~ 0.8 hour, collecting decoction, filters, and leaves standstill;
(3) cream processed: get the supernatant in step (2), being concentrated into relative density is 1.1 ~ 1.2, puts to room temperature cooling, adds ethanol and make alcohol content reach 70%, stir evenly, leave standstill, get supernatant, reclaim ethanol, be condensed into the clear paste that relative density is 1.28;
(4) granulate: get the clear paste in step (3), add sucrose, dextrin, make granule, dry, mixing, to obtain final product.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912472A (en) * | 2010-08-13 | 2010-12-15 | 黄文珍 | Chinese medicinal composition for treating habitual constipation and preparation method thereof |
| CN102078506A (en) * | 2009-11-27 | 2011-06-01 | 赵莉 | Traditional Chinese medicine composition for constipation |
| CN102106969A (en) * | 2011-01-28 | 2011-06-29 | 秦军 | Traditional Chinese medicine for treating deficiency constipation |
| CN102258705A (en) * | 2010-05-28 | 2011-11-30 | 刘国昌 | Chinese medicine composition for treating constipation |
| CN102357198A (en) * | 2011-11-11 | 2012-02-22 | 赵君怡 | Chinese medicinal composition for treating constipation |
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- 2013-07-24 CN CN201310313573.5A patent/CN103432504B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102078506A (en) * | 2009-11-27 | 2011-06-01 | 赵莉 | Traditional Chinese medicine composition for constipation |
| CN102258705A (en) * | 2010-05-28 | 2011-11-30 | 刘国昌 | Chinese medicine composition for treating constipation |
| CN101912472A (en) * | 2010-08-13 | 2010-12-15 | 黄文珍 | Chinese medicinal composition for treating habitual constipation and preparation method thereof |
| CN102106969A (en) * | 2011-01-28 | 2011-06-29 | 秦军 | Traditional Chinese medicine for treating deficiency constipation |
| CN102357198A (en) * | 2011-11-11 | 2012-02-22 | 赵君怡 | Chinese medicinal composition for treating constipation |
Non-Patent Citations (1)
| Title |
|---|
| 龚琼模治疗消化系统疾病经验;甘淳等;《实用中西医结合临床》;20020430;第2卷(第2期);36-37 * |
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