CN107998359A - Control the Chinese medicine and preparation method of Gilt Uterus intimitis and Repeat breeding - Google Patents
Control the Chinese medicine and preparation method of Gilt Uterus intimitis and Repeat breeding Download PDFInfo
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Abstract
Invention is related to technical field of Chinese veterinary medicine, more specifically, it relates to treat Chinese medicine preparation of Gilt Uterus intimitis and Repeat breeding and preparation method thereof and application method.Include the component of following parts by weight：8 12 parts of motherwort, 37 parts of Ligusticum wallichii, 15 parts of baked ginger, 15 parts of radix bupleuri, 59 parts of Angelica sinensis, 37 parts of dianthus superbus, 15 parts of peach kernel, 15 parts of dandelion, 13 parts of radix glycyrrhizae；With promoting blood circulation and removing blood stasis, the effect of middle benefit gas tonifying Qi, for diseases such as abdominal pain due to blood stasis, retention of afterbirth, uterus suppurations.Its is curative for effect, rapid-action, cure rate is high, uneasy to recur.
Description
Technical field
The present invention relates to technical field of Chinese veterinary medicine, more specifically, it relates to treat Gilt Uterus intimitis and repeatly with not
Pregnant Chinese medicine preparation and preparation method thereof and application method.
Background technology
Since the feeding manner for breeding sow now is largely raised using position limiting fence, cause to fill during sow gestation
Componental movement, appearance is easy in childbirth and is had difficult labour or bradytoia, the situation such as powerless or retention of afterbirth of giving a birth.Prolonged bradytoia or
Artificial aiding-birth adds the infection probability of sow reproductive system.In addition have difficult labour, retention of afterbirth, Uterine Prolapse, operation is not during midwifery
Clean, operation is rough, causes disinfection when vulneratio uteri, postpartum infection and artificial insemination to be not thorough, boar reproduction during natural mating
There are pathogenic bacteria, rheuminess thing etc. to cause endometritis in organ or sperm, sow is malnutritive, excessively thin and weak, resistance
When power declines, non-pathogenic bacteria can also cause Gilt Uterus intimitis in its genital tract.In recent years, the hair of Gilt Uterus intimitis
Sick rate is 20% or so, and some pig farm incidence may be up to more than 40%.Gilt Uterus intimitis is in pig breeding dysfunction disease
One of principal disease, if affected pig cannot be treated timely and effectively, often switchs to recessive or chronic infection, lactation amount reduces,
Agalasisa or milk quality are poor, grudge piglet lactation, cause suckling pig to have loose bowels, depauperation；Oestrous cycle wadding disorderly, is matched somebody with somebody not repeatly
Pregnant, farrowing is few, the disease such as production stillborn foetus.If after developing into obstinate membranous endometritis, production sow mortality can be increased, and
Easy scabies secondary infection other diseases, and increase the loss on pig farm.
Since the sick cause of disease is more complicated, symptomatic treatment is not easy.Treatment method has：To in vagina flow out Catarrhal slurries or
The physically weak sow of clear yellow viscous thing improves raising, and with reference to uterine irrigation, flushing liquor is 40 DEG C of 1 ‰ KMnO4Aqueous solution 500ml, punching
Once injected after washing and dissolved 1,000,000 unit of penicillin, the physiological saline 20ml of 1,000,000 unit of streptomysin.To being flowed from vagina
Go out the sow of the secretion of meter swill sample entrainment clot or purulence, every pig muscle injection 10ml sulfonamides and synergist.These are controlled
Treatment method is on the one hand very troublesome, and curative effect is not high；On the other hand, after drug therapy, medicament residue is caused, influences suckling pig life
Long, oestrus of sow is postponed, and greater loss is brought to production.
Chinese invention patent CN104012798B discloses feed, the Chinese medicine composition for treating Gilt Uterus intimitis
And preparation method, feed include feed vector and the Chinese medicine composition for treating Gilt Uterus intimitis, Chinese medicine composition bag
Include honeysuckle, Cortex Phellodendri, plantain seed, umbellate pore furgus, rhizoma alismatis, radix glycyrrhizae, Angelica sinensis, Ligusticum wallichii, motherwort, radix astragali, Herba Andrographitis, kuh-seng, cordate houttuynia,
Sweet wormwood, purple perilla, Chinese yam, Herba Epimedii, Schisandra chinensis, Lu Bazi, Fructus Aurantii and the root of three-nerved spicebush.Sow is controlled using above-mentioned Chinese medicine composition
Experiment, cure rate 83.3% are treated, the speed regulation healing number of 1-2 weeks for being investigated healing accounts for the 14.8% of total healing number, 3-4
The healing number in week accounts for the 51.85% of total healing number, and the healing number of the 5-6 weeks accounts for the 33.33% of total healing number.Cured relative to Western medicine
Performance has very big lifting, but still has to be hoisted.
Chinese invention patent CN107047931A discloses one kind and treats the feeding of Gilt Uterus intimitis Selenium-enriched fermentation Chinese herbal medicine
Feed additives, 20 grams of Selenium-enriched fermentation tealeaves, 10 grams of rhizoma anemarrhenae, 10 grams of dogwood fruit, 10 grams of moutan bark, 10 grams of rhizoma alismatis, 12 grams of umbellate pore furgus, drought
10 grams of lotus grass, 10 grams of Cortex Phellodendri, 10 grams of Rhizoma Atractylodis Macrocephalae, 10 grams of peach kernel, 10 grams of the seed of cowherb, 10 grams of Ligusticum wallichii, 12 grams of Sargent gloryvine, 10 grams of Angelica sinensis,
12 grams of radix cyathulae, 10 grams of Fructus Aurantii, 12 grams of the dried rhizome of rehmannia, licorice 10 is restrained into.Such scheme, which also has Gilt Uterus intimitis, to be compared
Good effect, cure rate 87%-90%, but Chinese herbal medicine is added in feed, the amount of taking medicine of more difficult control sow, in reality
It is possible that sow dosage not enough causes the situation of curative effect difference to occur during the use of border.
The content of the invention
In view of the deficienciess of the prior art, the first object of the present invention is to provide treatment Gilt Uterus intimitis and matches somebody with somebody repeatly
Infertile Chinese medicine preparation, has the advantages that curative for effect, rapid-action, cure rate is high, uneasy to recur.
The present invention above-mentioned technical purpose technical scheme is that：Treat Gilt Uterus intimitis and
The Chinese medicine preparation of Repeat breeding, includes the component of following parts by weight：8-12 parts of motherwort, 3-7 parts of Ligusticum wallichii, 1-5 parts of baked ginger, bavin
1-5 parts of Hu, 5-9 parts of Angelica sinensis, 3-7 parts of dianthus superbus, 1-5 parts of peach kernel, 1-5 parts of dandelion, 1-3 parts of radix glycyrrhizae.
The pharmacological property and drug effect of each Chinese herbal medicine are as follows：
Motherwort
Meridian distribution of property and flavor：It is bitter, pungent, it is slightly cold, Return liver, pericardium, bladder warp；
Effect：Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema are clearing heat and detoxicating；
Cure mainly：For irregular menstruation, dysmenorrhoea Amenorrhea, lochiorrhagia, oedema oliguria, sore swollen toxin；
Effect：With promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, clearing heat and detoxicating effect.
Ligusticum wallichii
Meridian distribution of property and flavor：It is pungent, warm, Return liver, courage, pericardium channel；
Effect：Blood-activating and qi-promoting, wind-expelling pain-stopping；
Cure mainly：Promote breath and open depression, method wind-dryness is wet, promoting blood circulation and stopping pain.It is dizzy to control air-cooled headache rotation, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, hardly possible
Production, postpartum stasis block pain, ulcer sores.For irregular menstruation, closed dysmenorrhea, lump in the abdomen abdominal pain, chest side of body shouting pain, tumbling and swelling, has a headache,
Arthralgia pain due to rheumatism；
Effect：Immune function, antiasthmatic effect are adjusted, suppresses platelet aggregation, antitumor action, improves renal function, improves lung work(
Cardiovascular function, excited uterus effect, can be improved.
Baked ginger
Meridian distribution of property and flavor：It is pungent, hot, returns spleen, stomach, kidney channel；
Effect：Warming channel for arresting bleeding, warm in pain；
Cure mainly：Lose blood for the deficiency of yang, hematemesis uterine bleeding, deficiency-cold in spleen and stomach, abdominal pain vomiting and diarrhoea.
Effect：Warming spleen and stomach for dispelling cold, warming channel for arresting bleeding.
Radix bupleuri
Meridian distribution of property and flavor：Cold nature, bitter, pungent, return liver warp, gallbladder channel；
Effect：Has soothing liver-gallbladder, thin gas solution is strongly fragrant, dissipates effect of fire；
Cure mainly：Stagnation of QI due to depression of the liver, sternal rib pain, rectal prolapse, uterus come off, irregular menstruation；
Effect：Saturating table expels the heat-evil, and soothing liver-qi stagnation, rises and lift yang-energy.
Angelica sinensis
Meridian distribution of property and flavor：It is sweet, pungent, warm, Return liver, the heart, the spleen channel；
Effect：Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation；
Cure mainly：The all cards of the main deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, abdominal mass knot gather, uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness,
Intestines are dry and shit is difficult, weight, ulcer sores, injury from falling down after dysentery characterized by blood in the stool；
Effect：Strengthen immune function, anti-inflammatory effect, antitumor action, improve lung function, antibacterial action, remove free radical function,
Improve cardiovascular function, improve blood function, excited uterus effect, sedation, diuresis, radiation-resisting functional.
Dianthus superbus
Meridian distribution of property and flavor：Bitter, cold in nature, the thoughts of returning home, small intestinl channel；
Effect：There is the effect of inducing diuresis for treating strangurtia, invigorate blood circulation；
Cure mainly：Puckery pain is dripped for heat gonorrhea, blood strangury, urolithiasis, urinary obstruction, leaching, the Amenorrhea stasis of blood is cloudy；
Effect：There are diuresis, blood pressure lowering；There is obvious inhibiting effect to isolated frog heart, the rabbit heart；Still there is micro- haemocylolysis；It is right
Staphylococcus aureus, Escherichia coli, typhoid bacillus, shigella flexneri, Pseudomonas aeruginosa have inhibitory action.
Peach kernel
Meridian distribution of property and flavor：It is bitter, sweet, flat, the thoughts of returning home, liver, large intestine channel.
Effect：Promoting blood circulation, relaxes bowel, relieving cough and asthma.
Cure mainly：For closed dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, lung carbuncle acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.
Effect：Antiasthmatic effect, antitussive effect, the effect of protection liver, anticoagulation and antithrombus formation.
Dandelion
Meridian distribution of property and flavor：Bitter sweet, tremble with fear, and enters liver, stomach；
Effect：It is clearing heat and detoxicating, diuresis dissipating bind.
Cure mainly：Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute almond
Body is scorching, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections
Effect：With antibacterial, promoting lactation, antitumor, choleretic effect.
Radix glycyrrhizae
Meridian distribution of property and flavor：It is sweet, flat, the thoughts of returning home, spleen, lung, stomach；
Effect：Invigorate the spleen and benefit qi, moisten the lung and relieve the cough, it is clearing heat and detoxicating, alleviate analgesic, relax pharmacological property；
Cure mainly：For weakness of the spleen and the stomach, shortness of breath and fatigue, palpitation and severe palpitation, cough phlegm is few, pathopyretic ulcer, medicine food poisoning, gastral cavity abdomen shoot,
Four limbs contraction pain；
Effect：With adjusting body immunity effect, anti-aging effects, anti-inflammatory effect, resisting pathogenic microbes effect, calm work
With, refrigeration function, antitumor action, improve Cardiovascular, antitussive action, phlegm-dispelling functions, anti-ulcer effect, enhancing body it is resistance to
Anoxic and stress ability.
The present invention is made of motherwort, Ligusticum wallichii, baked ginger, radix bupleuri, Angelica sinensis, dianthus superbus, peach kernel, dandelion, radix glycyrrhizae, has promoting blood circulation
Stagnation resolvation, the effect of middle benefit gas tonifying Qi, for diseases such as abdominal pain due to blood stasis, retention of afterbirth, uterus suppurations.In the formula using Ligusticum wallichii, peach kernel,
Motherwort promoting blood circulation.Motherwort has promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, clearing heat and detoxicating effect, for the menstruation caused by blood stasis
It is uncomfortable, dysmenorrhoea, Amenorrhea, postpartum abdominal pain or the disease such as lochiorrhagia, sore and toxic.The pungent scattered temperature of Ligusticum wallichii is logical, can promoting blood circulation to adjust
Through, but can promote breath and open depression and relieve pain, be blood in gas medicine, for the irregular menstruation caused by stagnation of QI and blood, dysmenorrhoea, amenorrhoea, postpartum
Stasis of blood, with Angelica sinensis compatibility, is used for blood stasis and swelling pain together with peach kernel.Baked ginger has effects that warming spleen and stomach for dispelling cold, warming channel for arresting bleeding.Radix bupleuri
Can be with Angelica sinensis with using, for seeing irregular menstruation or dysmenorrhoea caused by stagnation of liver qi.Angelica sinensis acrid-sweet flavor, is not only apt to enrich blood, but also kind promoting blood circulation
Analgesic, is replenishing and activating blood menstruation regulating key medicine, for irregular menstruation, dysmenorrhoea, often with Ligusticum wallichii with using, for blood stasis amenorrhoea, dysmenorrhoea, with peach
The drug for invigorating blood circulation and eliminating stasis such as benevolence are the same as use.The sweet temperature compensation blood of Angelica sinensis, can buttress healthy tendency, and can activating blood circulation and reducing swelling analgesic.Peach kernel bitter drop-down, promoting blood circulation
Dissolving stasis effect is stronger, with Angelica sinensis, Ligusticum wallichii with using, for postpartum stasis of blood.Radix glycyrrhizae life is not only apt to detoxify with cool in nature, but can heat-clearing,
And there is relieving spasm to stop pain effect.By the fiting effect of above component, treatment Gilt Uterus intimitis is curative for effect, it is rapid-action, control
More rate is high, uneasy to recur.
The present invention is further arranged to：Include the component of following parts by weight：9-11 parts of motherwort, 4-6 parts of Ligusticum wallichii, baked ginger
2-4 parts, 2-4 parts of radix bupleuri, 6-8 parts of Angelica sinensis, 4-6 parts of dianthus superbus, 2-4 parts of peach kernel, 2-4 parts of dandelion, 1.5-2.5 parts of radix glycyrrhizae.
Find that, using above-mentioned ratio of weight and number, more preferably, cure rate is more for the drug effect of the Chinese medicine preparation of the invention through experiment
Height, and it is shorter to cure required time.
The present invention is further arranged to：The parts by weight of radix bupleuri and dianthus superbus are equal.
Found through clinical trial, when the parts by weight of radix bupleuri and dianthus superbus are equal, curative effect is more preferable.
The second object of the present invention is to provide a kind of Chinese medicine preparation for preparing treatment Gilt Uterus intimitis and Repeat breeding
Method, have the advantages that preparation method is simple, prepare the time required to it is short.
The present invention above-mentioned technical purpose technical scheme is that：One kind prepares above-mentioned treatment sow
The method of the Chinese medicine preparation of endometritis and Repeat breeding comprises the following steps：
Step 1：Each bulk pharmaceutical chemicals of Chinese medicine preparation are weighed in proportion spare；
Step 2：Process, take suitable dianthus superbus and radix bupleuri, after dianthus superbus and radix bupleuri are mixed, be put into it is vinegar-fried in pot, after having fried, general
Radix bupleuri and dianthus superbus dry；
Step 3：Radix bupleuri in motherwort, Ligusticum wallichii, baked ginger, Angelica sinensis, peach kernel, dandelion, radix glycyrrhizae and step 2 and dianthus superbus are mixed
Close, mixed bulk pharmaceutical chemicals are processed and are ground into pulvis；
Step 4：Above-mentioned pulvis is encapsulated into packaging bag.
It is vinegar-fried by being carried out to dianthus superbus and radix bupleuri, the drug effect of dianthus superbus and radix bupleuri is strengthened, is then mixed each bulk pharmaceutical chemicals
Closing crushing encapsulation can be made, compared to the preparation method for needing immersion, decocting repeatedly, the preparation method institute needed for the invention
The preparation time needed is short, and preparation process is simple, and production efficiency is high, more conducively promotes.
The present invention is further arranged to：It is 8-12 that radix bupleuri described in step 2, which adds dianthus superbus to close weight and the ratio of vinegar,：1.
Through experiment find, will the weight such as radix bupleuri and dianthus superbus mix after carry out it is vinegar-fried, then with other bulk pharmaceutical chemicals mix add
After work, it is more advantageous to improving the drug effect of the Chinese medicine preparation blood-activating analgetic of the invention, when radix bupleuri plus dianthus superbus close the heavy ratio mistake with vinegar
Gao Shi, acidity is excessive, makes the effect of radix bupleuri and dianthus superbus reduction, and when ratio is too low, the drug effect of radix bupleuri and dianthus superbus, which plays, not to be come out, and is passed through
It is 8-12 that experiment, which finds that radix bupleuri adds dianthus superbus to close weight and the ratio of vinegar,：When 1, effect is relatively more preferable.
After radix bupleuri and dianthus superbus carry out hybrid process with other bulk pharmaceutical chemicals, it is more advantageous to improving the Chinese medicine preparation stagnation resolvation of the invention
The drug effect of analgesic.
The present invention is further arranged to：It is 9-11 that the radix bupleuri, which adds dianthus superbus to close weight and the ratio of vinegar,：1.
Found through experiment, when radix bupleuri plus dianthus superbus conjunction weight and the ratio of vinegar are 9-11：When 1, manufactured Chinese medicine preparation stagnation resolvation stops
The drug effect of pain is more preferable.
The present invention is further arranged to：For vinegar-fried vinegar it is mature vinegar in step 2, and the number of degrees of the mature vinegar are
4-6 degree.
Found through experiment, radix bupleuri and dianthus superbus are carried out with mature vinegar vinegar-fried, be more advantageous to improving the drug effect of the Chinese medicine preparation.
Mature vinegar is using selected high quality sorghum, barley, pea as raw material, and whole production process is after " steaming, ferment, smoked, leaching " and " solarization " five
A step, no what chemical catalyst of work；Fully rely on biological spontaneous fermentation so that the beneficial in raw material is able to intact guarantor
Deposit, then by " summer volt shines, and the winter drags for ice " natural fermentation, get rid of the weed and keep the flower of the leek, spawn for mature vinegar.Use mature vinegar relative usage
The drug effect of Chinese medicine preparation is more preferable made of rice vinegar or light-coloured vinegar, cure rate higher.
The present invention is further arranged to：The number of degrees of the mature vinegar are 4-6 degree.
Through experiment find, with the mature vinegar of 4-6 degree radix bupleuri and dianthus superbus are carried out it is vinegar-fried be more advantageous to raising drug effect, Jin Erti
The cure rate of high illness sow.
The present invention is further arranged to：Mixed bulk pharmaceutical chemicals processing is ground into fine powders more than 80 mesh in step 3.
Powdered Chinese medicine preparation is more convenient to carry out feeding to sow, and is also easier to be digested absorption.
Beneficial effects of the present invention are：
One：The present invention is made of motherwort, Ligusticum wallichii, baked ginger, radix bupleuri, Angelica sinensis, dianthus superbus, peach kernel, dandelion, radix glycyrrhizae, is had and is lived
Blood stagnation resolvation, the effect of middle benefit gas tonifying Qi, for diseases such as abdominal pain due to blood stasis, retention of afterbirth, uterus suppurations.Imitated by the cooperation of above component
Fruit, treatment Gilt Uterus intimitis is curative for effect, rapid-action, cure rate is high, uneasy to recur.
Secondly：It is vinegar-fried by being carried out to dianthus superbus and radix bupleuri, strengthen the drug effect of dianthus superbus and radix bupleuri, then carry out each bulk pharmaceutical chemicals
Co-grinding encapsulation can be made, compared to the preparation method for needing immersion, decocting repeatedly, the preparation method needed for the invention
Required preparation time is short, and preparation process is simple, and production efficiency is high, easy to promote.
Embodiment
With reference to form and embodiment, the present invention will be described in detail.
Traditional Chinese veterinary medicine think sow suffer from endometritis and it is infertile be due to pass through, postpartum vessels of the uterus it is hollow, cult poison multiplies
Invaded in void, heat toxin twines lower Jiao of product, and qi depression to blood stasis, Liver Channel product is strongly fragrant, hinders healthy tendency greatly, the disease that the cold of insufficiency type is mingled with, belongs to vaginal discharge diseases category.Occur
The general constitutional symptom unobvious of sow of endometritis, simply show as loss of appetite or do not eat, and flow out white from intravaginal
Or faint yellow mucus (spleen kidney deficiency weak type), or clear yellow viscous thing is flowed out from vagina, it is attached to root of the tail, around vaginal orifice, hardly possible of smelling as of rotten fish
Hear (damp heat downward flowing type), or from vagina outflow such as rice swill sample mucus, carry clot or purulence secretly, band stench, influencing lactation, (heat toxin, which is stopped up, contains
Type), most pigs occur without Temperature changing, also have temperature of pig body slightly to raise, and sow is not cured person's heat and postpones or do not send out yet after ablactation
Feelings, influence to be impregnated.Chinese veterinarian thinks Gilt Uterus intimitis, during treatment should with wet, the hot, stasis of blood, void for direction, with air making-up and spleen enlivening,
Dampness elimination stop-band, QI invigorating righting are the rules for the treatment of.
According to above-mentioned theory and principle, the present invention proposes a kind of Chinese medicine for treating Gilt Uterus intimitis and Repeat breeding
Preparation, including motherwort, Ligusticum wallichii, baked ginger, radix bupleuri, Angelica sinensis, dianthus superbus, peach kernel, dandelion, radix glycyrrhizae.The present invention is by motherwort, river
Rhizome of chuanxiong, baked ginger, radix bupleuri, Angelica sinensis, dianthus superbus, peach kernel, dandelion, radix glycyrrhizae composition, have promoting blood circulation and removing blood stasis, the effect of middle benefit gas tonifying Qi, for
The diseases such as abdominal pain due to blood stasis, retention of afterbirth, uterus suppuration.Using Ligusticum wallichii, peach kernel, motherwort promoting blood circulation in the formula.Motherwort has
There are promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, clearing heat and detoxicating effect, for the irregular menstruation caused by blood stasis, dysmenorrhoea, Amenorrhea, postpartum abdominal pain
Or the disease such as lochiorrhagia, sore and toxic.The pungent scattered temperature of Ligusticum wallichii is logical, can promoting blood circulation relieved pain with menstruation regulating and promote breath and open depression, be
Gas medicine in blood, for the irregular menstruation caused by stagnation of QI and blood, dysmenorrhoea, amenorrhoea, postpartum stasis of blood, and Angelica sinensis compatibility, with peach
Benevolence is same to be used for blood stasis and swelling pain.Baked ginger has effects that warming spleen and stomach for dispelling cold, warming channel for arresting bleeding.Radix bupleuri can be with Angelica sinensis with using, for seeing irritability
Irregular menstruation or dysmenorrhoea caused by pent-up.Angelica sinensis acrid-sweet flavor, is not only apt to enrich blood, but also kind promoting blood circulation and stopping pain, is replenishing and activating blood menstruation regulating key medicine,
For irregular menstruation, dysmenorrhoea, often use together with Ligusticum wallichii, for blood stasis amenorrhoea, dysmenorrhoea, used together with drug for invigorating blood circulation and eliminating stasis such as peach kernels.Angelica sinensis
Sweet temperature compensation blood, can buttress healthy tendency, and can activating blood circulation and reducing swelling analgesic.Peach kernel bitter drop-down, promoting blood circulation effect is stronger, with Angelica sinensis, river
Rhizome of chuanxiong is with using, for postpartum stasis of blood.Radix glycyrrhizae life is not only apt to detoxify with cool in nature, but can heat-clearing, and have relieving spasm to stop pain effect.Pass through
The fiting effect of above component, treatment Gilt Uterus intimitis is curative for effect, rapid-action, cure rate is high, uneasy to recur.
27 kinds of Chinese medicine preparations are configured according to embodiment 1-20, the bulk pharmaceutical chemicals of comparative example 1-2 and weight proportion in table 1.
Table 1 answers contained raw material medicine, each raw material medicine phases in embodiment 1-20, comparative example 1-2 the remittance of weight
Always.
Embodiment 21
A kind of method for preparing the Chinese medicine preparation that Gilt Uterus intimitis and Repeat breeding are treated in embodiment 1, including following step
Suddenly：
Step 1：Each bulk pharmaceutical chemicals of Chinese medicine preparation are weighed in proportion spare；
Step 2：Process, after dianthus superbus and radix bupleuri are mixed, be put into it is vinegar-fried with 4 degree of mature vinegars in pot, after having fried, by radix bupleuri and Qu
The mixture of wheat dries；
Step 3：Radix bupleuri in motherwort, Ligusticum wallichii, baked ginger, Angelica sinensis, peach kernel, dandelion, radix glycyrrhizae and step 2 and dianthus superbus are mixed
Close, mixed bulk pharmaceutical chemicals are processed and are ground into pulvis, the fine powder being ground into more than 80 mesh；
Step 4：Aseptically above-mentioned pulvis is encapsulated in vacuum packaging bag.
The medicament preparation method of embodiment 2-20 and comparative example 1-2 is identical with embodiment 21.
Embodiment 22
A kind of method for preparing the Chinese medicine preparation that Gilt Uterus intimitis and Repeat breeding are treated in embodiment 1, embodiment 22 with
The difference of embodiment 21 is, mature vinegar is replaced with rice vinegar.
Application examples 1
A kind of method using 1 Chinese medicine preparation of embodiment, 150 postpartum sows are 80 grams oral daily, once a day, continuously take
5 days.
Using embodiment 2-20, comparative example 1-2, and the method for the Chinese medicine of the preparation of embodiment 22, with making for application examples 1
It is identical with method.
Comparison study example 1
Comparative example 1 is used as blank assay, does not do any processing to 150 postpartum sows.
Comparison study example 2
Antibiotic of the comparative example 2 to 150 postpartum sow intramuscular injection equivalent.
Comparison study example 3
A kind of antiviral health-care preparation, the percentage by weight of component are：Motherwort 24%, RADIX ANGELICAE SINEINSIS 15%, rhizome of chuanxiong 6%, peach kernel 6%,
Rhizoma zingiberis 5%, radix glycyrrhizae 5%, cordate houttuynia 7%, dandelion 10%, seed of cowherb 6%-9%, Fructus Forsythiae 8%, thick wood-fern rhizome 6%.
Preparation method is：1. commercially available screening and above-mentioned net medicinal material of weighing, have the dry ventilated environment of sanitation and hygiene possessing
Lower processing and fabricating；2. process：Thick wood-fern rhizome is vinegar-fried, after drying, above-mentioned 11 taste Chinese medicine is mixed, is processed into fine powder；3. encapsulation：
Above-mentioned pulvis is encapsulated in vacuum packaging bag by pulvis sealing machine, both obtains antiviral health-care preparation.
Above-mentioned antiviral health-care preparation is taken orally to 150 postpartum sows.
Clinical trial：Sow postpartum is not to have inflammation of uterus, and any processing need not be done after having many Farrowings, but
It is, in order to prevent the generation of endometritis that most people still use antibiotic treatment, and Chinese medicine processing.These three modes
After having handled, contrast, standard is：In five days postpartum, rear private parts is clean, is retracted to normal condition, and lactation is normal, and feeding is just
Often, lactation is normal, breeds after wean normal, to be used as processing ultimate criterion to breeding after milk.By embodiment 1-27 according to implementation
The mode medicine feed of example 56-83, and the handling result of comparative example 1-2 collect to obtain below table.
Table 2 is the Chinese medicine pair prepared using embodiment 1-20, embodiment 22, comparative example 1-2 and Comparison study example 1-3
The result that 150 postpartum sows are handled collects.
By above table it can be found that if sow postpartum is without any processing, incidence is about 21%, beat after antibiotic have it is certain
Improve, incidence drops to 12%, takes the Chinese medicine of Comparison study example 3, and incidence drops to 11.3%, with the Chinese medicine of the present invention
Preparation carries out prevention, and incidence is less than 9%, wherein the Gilt Uterus intimitis incidence for taking the Chinese medicine of embodiment 5 is only
6.7%, the Gilt Uterus intimitis incidence for taking 7 Chinese medicine of embodiment is 2.7%, takes sow of 10 Chinese medicine of embodiment
Endometrium inflammation incidence 4.0%, the Gilt Uterus intimitis incidence for taking the Chinese medicine of embodiment 15 is only 2.0%, embodiment
17 and embodiment 18 in motherwort, baked ginger, dandelion, radix glycyrrhizae parts by weight change, do not significantly affect Gilt Uterus intimitis
Incidence.Radix bupleuri, dianthus superbus, which close weight embodiment 15 opposite with the ratio of vinegar, in embodiment 19 and embodiment 20 certain change,
The Gilt Uterus intimitis incidence for taking Chinese medicine is slightly decreased, but is still substantially better than Comparison study example 1-3.Embodiment 22
It is middle mature vinegar is replaced with into rice vinegar also to have a certain impact to drug effect.Radix bupleuri, dianthus superbus close the ratio mistake of weight and vinegar in comparative example 1
Low, the ratio of radix bupleuri, dianthus superbus conjunction weight and vinegar is excessive in comparative example 2 has all significantly affected the Gilt Uterus intimitis for taking Chinese medicine
Incidence, incidence are 90%.And found by upper table, when radix bupleuri, dianthus superbus are when weight, drug effect is more preferable.Therefore according to this hair
The Chinese medicine of bright proposition is carried out prevention to postpartum sow and is fed, and can largely reduce the loss on pig farm.
In addition the sow of Chinese medicine of the present invention also to having taken embodiment 7 and embodiment 15 has carried out the prison up to 2 years
Control, the sow that discovery postpartum cures are only 1% in incidence in two years.
Sow to having occurred and that endometritis, there is clinical symptoms, body temperature rise, and rear private parts has mycopus outflow,
Lactation is reduced, and the method using Chinese medicine of the present invention is 100 grams of the daily oral traditional Chinese medicine of sick pig, disposable oral or at twice
It is oral, for the sow not eaten, raw egg or glucose food calling are added in Chinese medicine preparation, and ensure dosage, for disease
For feelings than more serious, the sow for refusing feeding once gavages 100g medicaments.
By the Chinese medicine in embodiment 1-20, embodiment 22, comparative example 1-2, application examples comparative example 3 respectively according to above-mentioned side
Formula gives 100 diseased sow medicine feeds, obtains table 3；Comparison study example 4 is further included in table 3, comparative example 4 is that 100 have been sent out
The sow of raw endometritis is using the processing method for injecting appropriate antibiotic.Criterion recovers normal for feeding, and lactation is just
Often, rear private parts is flowed out without secretion, and breeding is normal.
Table 3 is to having occurred and that intrauterine using embodiment 1-20, embodiment 22 and comparative example 1-2, Comparison study example 3-4
The result that 100 sows of film inflammation are treated collects.
It can be obtained by table 3, the sow feeding for having more than 94 in embodiment 1-20 recovers normal, and the sow lactation of more than 92 is just
Often, more than 95% sow normally breeds.Each experiment value is above the experiment value of other embodiments in embodiment 7 and embodiment 15,
In 100 sows wherein tested, embodiment 7 has 98 sow feedings to recover normal, and 97 sow lactations are normal, 98% mother
Pig normally breeds.There are 99 sow feedings to recover normal in embodiment 15,97 sow lactations are normal, and 98% sow is normally matched somebody with somebody
Kind.The significantly larger than data of comparative example 3, therapeutic effect have very big lifting.Embodiment 22 changes mature vinegar into rice vinegar, or contrast
In example 1-2 radix bupleuri, dianthus superbus close weight and vinegar ratio it is too low or excessive all have a certain impact to normal breeding rate.Comparison study example
3 and Comparison study example 4 feeding recover normal condition, lactation is normal, normal breeding situation all compare it is relatively low, therefore the present invention
Chinese medicine therapeutic effect it is also fine.
Contrast to Repeat breeding treatment, no comparativity, antibiotic do not possess this function.
Sow Repeat breeding treatment method：After oestrus of sow, begin to use the Chinese medicine of the embodiment of the present invention 7 and embodiment 15
Agent, daily 100 grams, by several times feeding or it is disposable oral can, the breeding same day reuses, and is reused once after breeding
, summarized respectively by 350 sick pig treatments, seance effective percentage reaches 87% and 90%.
Obtained Chinese medicine in Comparison study example 3 is treated 50 repeatly with not using treatment method same as mentioned above
Pregnant sow, cure rate are only 10%.
In conclusion the treatment Gilt Uterus intimitis of the present invention and the Chinese medicine preparation of Repeat breeding,（1）It is curative for effect,
Postpartum sow is handled, the ratio that postpartum sow is normally bred is up to 98%, higher than not processing or anti-by injecting
The ratio for the sow that raw element can normally be bred after being handled.To suffer from the sow of endometritis using the Chinese medicine preparation into
Row processing, its cure rate may be up to 98%, than the treatment effect using Chinese medicine made from injection of antibiotics and Comparison study example 3
It is better.（2）Healing time is short, and 5 days postpartum normal breeding rate is up to 98%.（3）Preparation method is simple, shorter the time required to preparing.
（4）Application method is clear and definite, exact to define dosage, reduces that dose is wrong since sow takes, and influences curative effect
Phenomenon occurs.
This product begins to use from developing, and treatment sow Repeat breeding is efficient up to 96% up to 2000 bulls, treats sow
Endometritis and uterus contracting purulence are efficient up to 99% up to 3147, and cure rate is up to 95%.
The above is only the preferred embodiment of the present invention, and protection scope of the present invention is not limited merely to above-mentioned implementation
Example, all technical solutions belonged under thinking of the present invention belong to protection scope of the present invention.It should be pointed out that for the art
Those of ordinary skill for, some improvements and modifications without departing from the principles of the present invention, these improvements and modifications
It should be regarded as protection scope of the present invention.
Claims (9)
1. a kind of Chinese medicine preparation for treating Gilt Uterus intimitis and Repeat breeding, it is characterised in that including following parts by weight
Component：8-12 parts of motherwort, 3-7 parts of Ligusticum wallichii, 1-5 parts of baked ginger, 1-5 parts of radix bupleuri, 5-9 parts of Angelica sinensis, 3-7 parts of dianthus superbus, peach kernel 1-5
Part, 1-5 parts of dandelion, 1-3 parts of radix glycyrrhizae.
2. the Chinese medicine preparation for the treatment of Gilt Uterus intimitis according to claim 1 and Repeat breeding, it is characterised in that bag
Include the component of following parts by weight：9-11 parts of motherwort, 4-6 parts of Ligusticum wallichii, 2-4 parts of baked ginger, 2-4 parts of radix bupleuri, 6-8 parts of Angelica sinensis, Qu
4-6 parts of wheat, 2-4 parts of peach kernel, 2-4 parts of dandelion, 1.5-2.5 parts of radix glycyrrhizae.
3. the Chinese medicine preparation for the treatment of Gilt Uterus intimitis according to claim 1 and Repeat breeding, it is characterised in that bavin
It is recklessly equal with the parts by weight of dianthus superbus.
A kind of 4. Chinese medicine system for the treatment of Gilt Uterus intimitis prepared as described in claim 1-3 any one and Repeat breeding
The method of agent, it is characterised in that comprise the following steps：
Step 1：Each bulk pharmaceutical chemicals of Chinese medicine preparation are weighed in proportion spare；
Step 2：Process, after dianthus superbus and radix bupleuri are mixed, be put into vinegar-fried in pot, after having fried, radix bupleuri and dianthus superbus are dried；
Step 3：Radix bupleuri in motherwort, Ligusticum wallichii, baked ginger, Angelica sinensis, peach kernel, dandelion, radix glycyrrhizae and step 2 and dianthus superbus are mixed
Close, mixed bulk pharmaceutical chemicals are processed and are ground into pulvis；
Step 4：Above-mentioned pulvis is encapsulated into packaging bag.
A kind of 5. side of Chinese medicine preparation for preparing treatment Gilt Uterus intimitis and Repeat breeding according to claim 4
Method, it is characterised in that it is 8-12 that radix bupleuri described in step 2, which adds dianthus superbus to close weight and the ratio of vinegar,：1.
A kind of 6. side of Chinese medicine preparation for preparing treatment Gilt Uterus intimitis and Repeat breeding according to claim 5
Method, it is characterised in that it is 9-11 that the radix bupleuri, which adds dianthus superbus to close weight and the ratio of vinegar,：1.
A kind of 7. side of Chinese medicine preparation for preparing treatment Gilt Uterus intimitis and Repeat breeding according to claim 4
Method, it is characterised in that for vinegar-fried vinegar be mature vinegar in step 2, and the number of degrees of the mature vinegar are 4-6 degree.
A kind of 8. side of Chinese medicine preparation for preparing treatment Gilt Uterus intimitis and Repeat breeding according to claim 5
Method, it is characterised in that mixed bulk pharmaceutical chemicals processing is ground into fine powders more than 80 mesh in step 3.
A kind of 9. side of Chinese medicine preparation for preparing treatment Gilt Uterus intimitis and Repeat breeding according to claim 4
Method, it is characterised in that aseptically pulvis is encapsulated in vacuum packaging bag in step 4.
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| CN116115727A (en) * | 2022-12-17 | 2023-05-16 | 内蒙古自治区农牧业科学院 | Traditional Chinese veterinary medicine composition for postpartum uterus repair of cows and preparation method thereof |
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Application publication date: 20180508 |