CN103356800A

CN103356800A - Medicine for treating lumbago and preparation method thereof

Info

Publication number: CN103356800A
Application number: CN2013103096124A
Authority: CN
Inventors: 肖振锋
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-07-23
Filing date: 2013-07-23
Publication date: 2013-10-23
Anticipated expiration: 2033-07-23
Also published as: CN103356800B

Abstract

The invention discloses a medicine for treating lumbago and a preparation method thereof. The medicine is mainly prepared from Chinese angelica, Ligusticum wallichii, raw rehmannia root, Radix Paeoniae Alba, banksia rose, pawpaw and eucommia according to a certain weight ratio. The medicine provided by the invention has functions of dispelling pathogenic wind, removing dampness, promoting blood circulation to arrest pain, removing moisture and relaxing muscles and tendons, nourishing liver and kidney and strengthening the bones and muscles, and has advantages of good curative effect, fast effectiveness and high cure rate when used for treating lumbago.

Description

A kind of medicine for the treatment of lumbago and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of lumbago and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Pain in the lumbar region refers to that the disease of pain occurs for waist one side and both sides or just medium place, causes that the reason of lumbago is more, and majority is due to the lumbar soft tissue chronic strain, the chronic strain lumbago is often in tired postemphasis, alleviate after the rest, characteristic of pain mostly is sour distending pain and the sense of waist weight, is afraid of to do the action of bending over.The traditional Chinese medical science thinks that waist is house of kidney, so the relation of lumbago and kidney is the closest, the reason of lumbago can be summarized as diseases caused by exogenous pathogenic factor and internal injury two classes.At present, Western medicine can't effectively effect a radical cure lumbago fast, and more side effect is arranged, and therefore, there is very large demand in people to the Chinese medicine of effective treatment lumbago.

Summary of the invention

The inventor has finally found the medicine of effective treatment lumbago, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

Purpose of the present invention just provides a kind of composition of medicine that can effectively treat lumbago.

Another object of the present invention has just provided the preparation method of this composition of medicine.

Medicine of the present invention selects Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Paeoniae Alba, the Radix Aucklandiae, Fructus Chaenomelis, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, Rhizoma Atractylodis medicine to make up, with these drug regimens so that each efficacy of drugs produces synergism, thereby can effectively treat the recurrence of lumbago.Wherein selecting Radix Angelicae Sinensis is that temperature enters the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after the bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Rhizoma Chuanxiong to be because its nature and flavor are hot, temperature enters liver, gallbladder meridian, and activating QI to alleviate the depression is arranged, dispeiling pathogenic wind and removing dampness, and the function of promoting blood circulation and stopping pain is controlled air-cooled headache and is revolved dizzyly, and the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid is controlled the calentura excessive thirst, yin asthenia generating intrinsic heat, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.Selecting Radix Paeoniae Alba is that cold enters liver, spleen channel, and nourishing blood to suppress the hyperactive liver is arranged because of its nature and flavor picric acid, slow middle pain relieving, and yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select the Radix Aucklandiae to be because its nature and flavor are arduous, temperature enters lung, liver, spleen channel, and promoting the circulation of QI to relieve pain are arranged, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and dysentery tenesmus, colic of cold type are had loose bowels in vomiting.Select Fructus Chaenomelis to be because its nature and flavor are sour, temperature enters liver, spleen channel, and suppressing the hyperactive liver and easing the stomach is arranged, and the function of the Shujin that dries being controlled the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.Selecting the Cortex Eucommiae is that temperature enters liver, kidney channel, and invigorating the liver and kidney is arranged because of the sweet little suffering of its nature and flavor, bone and muscle strengthening, and antiabortive function is controlled the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, hypertension.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, give birth to and use dissipating blood stasis blood, subduing inflammation is controlled gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury is ripely used invigorating the liver and kidney, and bone and muscle strengthening is controlled waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Select Olibanum to be because its nature and flavor are arduous, temperature enters the heart, liver, spleen channel, and regulating qi and activating blood is arranged, and analgesic therapy chases after malicious function, controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select Myrrha to be because its nature and flavor are bitter, flat, enter Liver Channel, loose blood blood stasis removing is arranged, the function of subduing swelling and relieving pain is controlled and is fallen damage, incised wound, muscles and bones, all Tong ， of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.Select Rhizoma Et Radix Notopterygii to be because its nature and flavor are arduous, temperature enters bladder, kidney channel, and loose exterior cold is arranged, wind-damp dispelling, and the function in sharp joint, the wind and cold that cures cold, it is lossless to have a headache, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.Select Rhizoma Atractylodis to be because its nature and flavor are arduous, temperature enters spleen, stomach warp, and spleen invigorating is arranged, dampness, and resolving depression is warded off dirty function, control wet the Sheng and be stranded spleen, the asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, dysentery is had loose bowels in vomiting, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.

The drug dose of the present invention's combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope

Radix Angelicae Sinensis 10-20 gram Rhizoma Chuanxiong 10-20 gram Radix Rehmanniae 10-20 gram

Radix Paeoniae Alba 10-20 gram Radix Aucklandiae 6-10 gram Fructus Chaenomelis 10-20 gram

Cortex Eucommiae 10-20 gram Radix Achyranthis Bidentatae 10-20 gram Olibanum 8-15 gram

Myrrha 8-15 gram Rhizoma Et Radix Notopterygii 8-15 gram Rhizoma Atractylodis 8-15 gram

Preferable amount is

Radix Angelicae Sinensis 15 gram Rhizoma Chuanxiongs 15 gram Radix Rehmanniae 15 grams

The Radix Paeoniae Alba 15 gram Radix Aucklandiae 8 gram Fructus Chaenomeliss 15 grams

The Cortex Eucommiae 15 gram Radix Achyranthis Bidentataes 15 gram Olibanums 10 grams

Myrrha 10 gram Rhizoma Et Radix Notopterygiis 10 gram Rhizoma Atractylodis 10 grams

The preparation method of medicine of the present invention is as follows

One, gets the raw materials ready

1, Radix Angelicae Sinensis: choose decontamination, clean, moistening slightly dries in the air when suitable to inside and outside humidity, and section is dried;

2, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;

3, Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit is cut sheet, drying, and sieve removes chip;

4, Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;

5, the Radix Aucklandiae: crude drug in whole put in the clear water clean, pull out, moistening made soft in 12-24 hours, and section is dried;

6, Fructus Chaenomelis: clear water is cleaned, and slightly soaks, and moistening is to thoroughly, puts in the food steamer to cook, and takes advantage of fervent sheet, weather exposure, with by red turn atropurpureus till;

7, the Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;

8, Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

9, Olibanum: choose the sub-impurity of shakeout;

10, Myrrha: choose decontamination, break into fragment;

11, Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section is dried;

12, Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry.

Two, preparation

1, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Paeoniae Alba, the Radix Aucklandiae, Fructus Chaenomelis, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, the Rhizoma Atractylodis medicine of described weight being added 6 times of water gagings soaks, soak after 180 minutes, intense fire decocts boiling 25 minutes, use again slow fire boiling 25 minutes, and filtered to get decoction liquor for the first time.

2, the medicinal residues that filter are added 4 times of amounts of water, intense fire decocts boiling, uses slow fire boiling 20 minutes again, filters to get decoction liquor for the second time.

3, twice decoction liquor mixed, used again slow fire boiling 15 minutes, decoction liquor is divided into 3 doses takes.

Medicine of the present invention has dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain, and the Shujin that dries, invigorating the liver and kidney, the effect of bone and muscle strengthening is used for the treatment of lumbago, short treating period, instant effect, non-relapse after healing, has no side effect.

The specific embodiment

Below further set forth the beneficial effect of medicine of the present invention by test example, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg divides two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, serve on 7 days every day 2 times, observes the administration reaction every day, and the result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] Drug therapy lumbago of the present invention

1, physical data

Accept out-patient's totally 230 examples for medical treatment, its male patient's 150 examples, female patient 80 examples.

2, diagnostic criteria

The cause of disease of lumbago mostly be being invaded by exogenous pathogen, deficiency of kidney essence, troubled by sickness and old age, sprain and contusion fall pounce on, due to QI and blood is retarded by silt.Clinical manifestation is: cold-dampness type has the waist cold type of pain, and acid is swollen to weigh the features such as unfavorable, overcast and rainy aggravation of changing one's position.Damp-heat type has the bitter taste dysphoria with smothery sensation, oliguria with reddish urine, and with burning sensation, the symptom such as pain more when weather is damp and hot.Congestion type localized pain, such as cone as thorn, pitching is unfavorable, and with hematuria, day light night is heavy.Renal deficiency type is aching and limp heavy pain then, desire for being robbed and pressed, after the labor pain very, sleeping then alleviate, pale complexion, vexed xerostomia, happiness is warmed up and is afraid of cold hands and feet being not warm.

3, Therapeutic Method

Select above-mentioned medicament, take to the patient, each serving with 1 dose, every day early, middle and late respectively the clothes 1 time, 10 days is a course for the treatment of, takes continuously 5 courses for the treatment of.

4, efficacy assessment standard

Produce effects: lumbago transference cure, body constitution recover normal, observe half a year without the recidivist;

Take a turn for the better: the lumbago symptom is clearly better, and body constitution is progressively recovered;

Invalid: as not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

Figure 2013103096124100002DEST_PATH_IMAGE001

In above-mentioned treatment, with Drug therapy lumbago patient 230 examples of the present invention, produce effects 220 examples as a result, obvious effective rate is 95.65%, 6 examples that take a turn for the better, improvement rate is 2.61%, invalid 4 examples, total effective rate is 98.26%.

Claims

1. medicine for the treatment of lumbago, it is characterized in that: it is to be made by the crude drug in the following weight range:

Myrrha 8-15 gram Rhizoma Et Radix Notopterygii 8-15 gram Rhizoma Atractylodis 8-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Myrrha 10 gram Rhizoma Et Radix Notopterygiis 10 gram Rhizoma Atractylodis 10 grams.

3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:

(1) gets the raw materials ready

(1) Radix Angelicae Sinensis: choose decontamination, clean, moistening slightly dries in the air when suitable to inside and outside humidity, and section is dried;

(2) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;

(3) Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit is cut sheet, drying, and sieve removes chip;

(4) Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;

(5) Radix Aucklandiae: crude drug in whole put in the clear water clean, pull out, moistening made soft in 12-24 hours, and section is dried;

(6) Fructus Chaenomelis: clear water is cleaned, and slightly soaks, and moistening is to thoroughly, puts in the food steamer to cook, and takes advantage of fervent sheet, weather exposure, with by red turn atropurpureus till;

(7) Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;

(8) Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

(9) Olibanum: choose the sub-impurity of shakeout;

(10) Myrrha: choose decontamination, break into fragment;

(11) Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section is dried;

(12) Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;

(2) preparation

(1) Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Paeoniae Alba, the Radix Aucklandiae, Fructus Chaenomelis, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, the Rhizoma Atractylodis medicine of described weight being added 6 times of water gagings soaks, soak after 180 minutes, intense fire decocts boiling 25 minutes, used again slow fire boiling 25 minutes, filter, get for the first time decoction liquor;

(2) medicinal residues that filter are added 4 times of amounts of water, intense fire decocts boiling, uses slow fire boiling 20 minutes again, filters to get decoction liquor for the second time;

(3) twice decoction liquor mixed, used again slow fire boiling 15 minutes, decoction liquor is divided into 3 doses takes.