CN103356800B - Medicine for treating lumbago and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating lumbago and a preparation method thereof. The medicine is mainly prepared from Chinese angelica, Ligusticum wallichii, raw rehmannia root, Radix Paeoniae Alba, banksia rose, pawpaw and eucommia according to a certain weight ratio. The medicine provided by the invention has functions of dispelling pathogenic wind, removing dampness, promoting blood circulation to arrest pain, removing moisture and relaxing muscles and tendons, nourishing liver and kidney and strengthening the bones and muscles, and has advantages of good curative effect, fast effectiveness and high cure rate when used for treating lumbago.

Description

A kind of medicine for the treatment of lumbago and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of lumbago and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Pain in the lumbar region refers to that the disease of pain occurs for waist side and both sides or just medium place, causes the reason of lumbago more, most caused by lumbar soft tissue chronic strain, chronic strain lumbago is often in tired postemphasis, alleviate after rest, characteristic of pain mostly is sour distending pain and the sense of waist weight, is afraid of to bend over action.The traditional Chinese medical science is thought, waist is house of kidney, so the relation of lumbago and kidney is the closest, the reason of lumbago can be summarized as diseases caused by exogenous pathogenic factor and internal injury two class.At present, Western medicine effectively cannot effect a radical cure lumbago fast, and has more side effect, and therefore, people exist very large demand to the Chinese medicine of effectively treating lumbago.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment lumbago, thus completes the present invention.

Object of the present invention is just to provide a kind of composition of medicine effectively can treating lumbago.

Another object of the present invention just there is provided the preparation method of this composition of medicine.

Medicine of the present invention selects Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Paeoniae Alba, the Radix Aucklandiae, Fructus Chaenomelis, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, Rhizoma Atractylodis medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of lumbago.Wherein select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select the Radix Aucklandiae to be that temperature, enters lung, liver, spleen channel, have promoting the circulation of QI to relieve pain, the function of warming middle-JIAO for easing the stomach, control the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain because its nature and flavor are worked hard, vomiting, has loose bowels, dysentery tenesmus, colic of cold type.Fructus Chaenomelis is selected to be that temperature, enters liver, spleen channel, have suppressing the hyperactive liver and easing the stomach, the function of the relaxing muscles and tendons that dries, and controls convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery because its nature and flavor acid.Select the Cortex Eucommiae be because its nature and flavor sweet micro-pungent, temperature, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, antiabortive function, control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, vaginal bleeding during pregnancy for falling, hypertension.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid, flat, enter liver, kidney channel, life uses dissipating blood stasis blood, subduing inflammation, controls gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis is suffered from abdominal pain, sore throat, carbuncle, traumatic injury, ripe invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Select Olibanum to be that temperature, enters the heart, liver, spleen channel, have regulating qi and activating blood, analgesic therapy because its nature and flavor are worked hard, chase after the function of poison, control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Myrrha is selected to be that flat, enter Liver Channel, have loose blood blood stasis removing, the function of subduing swelling and relieving pain, controls and fall damage, incised wound, muscles and bones, trusted subordinate all Tong ， mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye because its nature and flavor are bitter.Rhizoma Et Radix Notopterygii is selected to be that temperature, enter bladder, kidney channel, have loose exterior cold, wind-damp dispelling, the function in sharp joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore because its nature and flavor are worked hard.Rhizoma Atractylodis are selected to be that temperature, enters spleen, stomach warp, have spleen invigorating, dampness, resolving depression, ward off dirty function because its nature and flavor are worked hard, control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.

The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Radix Angelicae Sinensis 10-20 gram of Rhizoma Chuanxiong 10-20 gram of Radix Rehmanniae 10-20 gram

Radix Paeoniae Alba 10-20 gram of Radix Aucklandiae 6-10 gram of Fructus Chaenomelis 10-20 gram

Cortex Eucommiae 10-20 gram of Radix Achyranthis Bidentatae 10-20 gram of Olibanum 8-15 gram

Myrrha 8-15 gram of Rhizoma Et Radix Notopterygii 8-15 gram of Rhizoma Atractylodis 8-15 gram

Preferable amount is

Radix Angelicae Sinensis 15 grams of Rhizoma Chuanxiongs 15 grams of Radix Rehmanniae 15 grams

Radix Paeoniae Alba 15 grams of Radix Aucklandiae 8 grams of Fructus Chaenomeliss 15 grams

The Cortex Eucommiae 15 grams of Radix Achyranthis Bidentataes 15 grams of Olibanums 10 grams

Myrrha 10 grams of Rhizoma Et Radix Notopterygiis 10 grams of Rhizoma Atractylodis 10 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;

2, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;

3, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;

4, Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;

5, the Radix Aucklandiae: put by crude drug in whole in clear water and clean, pull out, moistening makes soft for 12-24 hours, section, dries;

6, Fructus Chaenomelis: clear water is cleaned, and slightly soaks, moistening, to thoroughly, is put in food steamer and is cooked, take advantage of fervent sheet, weather exposure, with by red turn atropurpureus till;

7, the Cortex Eucommiae: removing rough bark, clean, run through, dice or strand, dry;

8, Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;

9, Olibanum: pick the sub-impurity of shakeout;

10, Myrrha: pick decontamination, breaks into fragment;

11, Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;

12, Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry.

Two, prepare

1, the Radix Angelicae Sinensis of described weight, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Paeoniae Alba, the Radix Aucklandiae, Fructus Chaenomelis, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, Rhizoma Atractylodis medicine are added 6 times of water gagings and soak, soak after 180 minutes, intense fire decocts boiling 25 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor.

2, add water the medicinal residues of filtration 4 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.

3, by twice decoction liquor mixing, then use slow fire boiling 15 minutes, decoction liquor be divided into 3 doses to take.

Medicine of the present invention has dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain, and dry relaxing muscles and tendons, invigorating the liver and kidney, and effect of bone and muscle strengthening, is used for the treatment of lumbago, short treating period, instant effect, non-relapse after healing, has no side effect.

Detailed description of the invention

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] Drug therapy lumbago of the present invention

1, physical data

Accept out-patient's totally 230 examples for medical treatment, its male patient 150 example, female patient 80 example.

2, diagnostic criteria

The cause of disease of lumbago mostly is being invaded by exogenous pathogen, deficiency of kidney essence, troubled by sickness and old age, sprain and contusion are fallen and flutterred, caused by QI and blood is retarded by silt.Clinical manifestation is: cold-dampness type has waist cold type of pain, and it is heavy that acid is swollen, the features such as unfavorable, overcast and rainy aggravation of changing one's position.Damp-heat type has bitter taste dysphoria with smothery sensation, oliguria with reddish urine, with burning sensation, and the more symptom such as pain when weather is damp and hot.Congestion type localized pain, if cone is as thorn, pitching is unfavorable, and with hematuria, day at light night is heavy.Renal deficiency type is aching and limp heavy pain then, desire for being robbed and pressed, and after labor, pain is very, sleeping then alleviate, pale complexion, vexed xerostomia, and happiness is warmed up and is afraid of cold, hands and feet being not warm.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 10 days, is a course for the treatment of, takes 5 courses for the treatment of continuously.

4, efficacy assessment standard

Effective: lumbago transference cure, body constitution recovers normal, observes half a year without recidivist;

Take a turn for the better: lumbago symptom is clearly better, and body constitution is progressively recovered;

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, by Drug therapy lumbago patient 230 example of the present invention, effective 220 examples of result, obvious effective rate is 95.65%, and take a turn for the better 6 examples, and improvement rate is 2.61%, and invalid 4 examples, total effective rate is 98.26%.

Claims (3)

1. treat a medicine for lumbago, it is characterized in that: it is made up of the crude drug in following weight range:

Radix Angelicae Sinensis 10-20 gram of Rhizoma Chuanxiong 10-20 gram of Radix Rehmanniae 10-20 gram

Radix Paeoniae Alba 10-20 gram of Radix Aucklandiae 6-10 gram of Fructus Chaenomelis 10-20 gram

Cortex Eucommiae 10-20 gram of Radix Achyranthis Bidentatae 10-20 gram of Olibanum 8-15 gram

Myrrha 8-15 gram of Rhizoma Et Radix Notopterygii 8-15 gram of Rhizoma Atractylodis 8-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Radix Angelicae Sinensis 15 grams of Rhizoma Chuanxiongs 15 grams of Radix Rehmanniae 15 grams

Radix Paeoniae Alba 15 grams of Radix Aucklandiae 8 grams of Fructus Chaenomeliss 15 grams

The Cortex Eucommiae 15 grams of Radix Achyranthis Bidentataes 15 grams of Olibanums 10 grams

Myrrha 10 grams of Rhizoma Et Radix Notopterygiis 10 grams of Rhizoma Atractylodis 10 grams.

3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;

(2) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;

(3) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;

(4) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;

(5) Radix Aucklandiae: put by crude drug in whole in clear water and clean, pull out, moistening makes soft for 12-24 hours, section, dries;

(6) Fructus Chaenomelis: clear water is cleaned, and slightly soaks, moistening, to thoroughly, is put in food steamer and is cooked, take advantage of fervent sheet, weather exposure, with by red turn atropurpureus till;

(7) Cortex Eucommiae: removing rough bark, clean, run through, dice or strand, dry;

(8) Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;

(9) Olibanum: pick the sub-impurity of shakeout;

(10) Myrrha: pick decontamination, breaks into fragment;

(11) Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;

(12) Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;

(2) prepare

(1) Radix Angelicae Sinensis of described weight, Rhizoma Chuanxiong, Radix Rehmanniae, Radix Paeoniae Alba, the Radix Aucklandiae, Fructus Chaenomelis, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, Rhizoma Atractylodis medicine are added 6 times of water gagings and soak, soak after 180 minutes, intense fire decocts boiling 25 minutes, use slow fire boiling again 25 minutes, filter, obtain first time decoction liquor;

(2) add water the medicinal residues of filtration 4 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;

(3) by twice decoction liquor mixing, then use slow fire boiling 15 minutes, decoction liquor be divided into 3 doses to take.