CN106039220A - External use medicine for treating knee osteoarthritis and preparation method thereof - Google Patents

External use medicine for treating knee osteoarthritis and preparation method thereof Download PDF

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CN106039220A
CN106039220A CN201610541986.2A CN201610541986A CN106039220A CN 106039220 A CN106039220 A CN 106039220A CN 201610541986 A CN201610541986 A CN 201610541986A CN 106039220 A CN106039220 A CN 106039220A
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radix
gram
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rhizoma
pick
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李本虎
房红霞
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses an external use medicine for treating the knee osteoarthritis and a preparation method thereof. The medicine is mainly prepared from radix clematidis, radix aconiti sinensis, aconitum kusnezoffii, radix astragali, phryma leptostachya, herba lycopodii, caulis spatholobi and radix saposhnikoviae according to a certain weight ratio. The medicine has functions of expelling wind and removing cold, removing moist and eliminating swelling, relaxing muscles and stimulating blood circulation, and settling pain and chasing poison and is high in cure rate and capable of making people free of relapse when used for treating the knee osteoarthritis.

Description

A kind of external used medicine treating knee joint osseous arthritis and preparation method thereof
Technical field
The present invention relates to a kind of medicine treating knee joint osseous arthritis, belong to the field of Chinese medicines.
Background technology
Osteoarthritis is also known as proliferative arthritis or osteoarthritis, and early symptom is that joint persistence is ached or lives Prominent sense twinge time dynamic, joint motion is dumb, and late period, sclerotin and cartilage hypertrophy, produced joint deformity, x-ray inspection display limit, joint Edge is sharp-pointed or has the symptoms such as bony spur is formed, and joint space narrows, subchondral bony sclerosis.Western medicine DeGrain, can only Control table not effect a permanent cure, and containing certain toxic and side effects.
Summary of the invention
Therefore, there is expectation and demand greatly in people's Chinese medicine external preferable to curative effect medicine, does not the most also have Finding about the relevant report of the present invention, the present inventor is through development test repeatedly, and by the checking repeatedly of clinical trial, The most successfully develop the medicine for the treatment of osteoarthritis, thus complete the present invention.
It is an object of the invention to provide a kind of composition of medicine treating knee joint osseous arthritis, to meet the need of patient Ask.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention be select Radix Clematidis, Radix Aconiti, Radix Aconiti Kusnezoffii, the Radix Astragali, Herba speranskiae tuberculatae, Herba Lycopodii, Caulis Spatholobi, Radix Saposhnikoviae, Rhizoma Drynariae, Ramulus Cinnamomi, Semen Strychni, Flos Carthami, Radix Cyathulae, Radix Et Rhizoma Rhei, Olibanum, Myrrha, Radix Dipsaci, Herba Taxilli, Radix Angelicae Sinensis, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Huang Cypress, the Cortex Eucommiae, Rhizoma Atractylodis, Rhizoma Alismatis, Semen Coicis, Rhizoma Curcumae Longae, Lignum Sappan, Rhizoma Chuanxiong are combined, by these drug regimens so that each medicine merit Effect produces synergism such that it is able to effectively treat the recurrence of osteoarthritis.Wherein Radix Clematidis is selected to be because its nature and flavor pungent Salty, temperature, poisonous, enter bladder warp, have wind-damp dispelling, the meridian dredging, expectorant saliva, dissipate the function of the hypochondriac lump, control gout, insensitive impediment, chills and pain of the waist and kness, Tinea pedis, malaria, abdominal mass accumulation, tetanus, tonsillitis, all a fishbone or other bone caught in the throat swallow.Selecting Radix Aconiti, different name Radix Aconiti, its nature and flavor are pungent, heat, Poisonous, enter spleen, the gate of vitality two warp, have dispelling cold and dampness, dissipate ailment said due to cold or exposure, warming the meridian, the function of pain relieving, control anemofrigid-damp arthralgia, severe and migratory arthralgia pain, extremity are arrested Contraction, hemiplegia, wind syndrome of head headache, trusted subordinate's cold type of pain, carbuncle of yin nature toxic swelling.Selecting Radix Aconiti Kusnezoffii, different name Radix Aconiti Kusnezoffii, its nature and flavor are pungent, heat, poisonous, Enter liver, spleen, lung meridian, search wind prevailing over dampness, dispersing cold for relieving pain, open expectorant, the function of detumescence, control anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, Wind syndrome of head, coldness and pain in the epigastrium, accumulation of phlegm in the hypochondrium, air parcel, cold-dysentery, sore throat, carbuncle, furuncle, scrofula.The Radix Astragali is selected to be because its nature and flavor sweet, tepor, Enter lung, spleen channel, raw by useful consolidating superficial resistance of defending, inducing diuresis to remove edema, poison holding, the function of granulation promoting, control spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle Do not burst or burst and hold back for a long time;Process by the function having invigorating middle warmer benefit, control internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, metrorrhagia and leukorrhagia and all The disease of weakness of QI blood deficiency.Select Herba speranskiae tuberculatae to be because its property and flavor of peppery and warm, dispel the wind, dehumidifying, relaxing muscles and tendons, invigorate blood circulation, the function of pain relieving, control wind Pain of dampness syndrome, muscles and bones contracture, skin ulcer tinea toxic swelling.Herba Lycopodii is selected to be because its nature and flavor toil, temperature, enter liver, stomach, kidney three warp, dispel the wind Cold expelling, dehumidifying detumescence, the function of relaxing muscles and tendons to promote blood circulation, control anemofrigid-damp arthralgia, joint aches, skin numbness, tetraparesis, edema, traumatic injury Damage.Select Caulis Spatholobi be because its property bitter but sweet flavor, temperature, enter the heart, spleen two warp, have invigorate blood circulation, the function of relaxing muscles and tendons, control soreness of waist and knee joint, Paralysis and numbness, menoxenia.Radix Saposhnikoviae is selected to be because its property acrid-sweet flavor, temperature, enter bladder, lung, spleen channel, deliver, dispel the wind, victory Wet, the function of pain relieving, control affection of exogenous wind-cold, headache, dizzy, stiffness of the nape, anemofrigid-damp arthralgia, joint aches, and extremity contraction is anxious, tetanus.Choosing It is because its nature and flavor bitter with Rhizoma Drynariae, temperature, enter liver, kidney channel, have the kidney invigorating, invigorate blood circulation, the function of hemostasis, control suffer from a deficiency of the kidney chronic diarrhea and lumbago, Rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.Ramulus Cinnamomi is selected to be because its property acrid-sweet flavor, Temperature, enters bladder, the heart, lung meridian, has diaphoresis expelling pathogenic factors from muscles, the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, takes on and carries on the back podomere ache, thoracic obstruction phlegm retention, Amenorrhea abdominal mass.Semen Strychni is selected to be because its nature and flavor bitter, cold, poisonous, there is scattered heat in blood, detumescence, the function of pain relieving, control throat numbness Bitterly, swollen ulcer drug, migratory arthralgia pain, fracture, and control facial paralysis, myasthenia gravis.Flos Carthami is selected to be because its nature and flavor pungent, Temperature, enters the heart, Liver Channel, has promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, controls amenorrhea, abdominal mass, difficult labour, stillborn fetus, disease that postpartum lochia can't go, the stasis of blood Blood is had a pain, carbuncle, injury from falling down.Select Radix Cyathulae to be because its nature and flavor to put down, the micro-hardship of bitter in the mouth, nontoxic, enter liver, kidney two warp, dispel Wind, dampness removing, stimulate the menstrual flow, the function invigorated blood circulation, dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea, abdominal mass.Select It is bitter, cold that Radix Et Rhizoma Rhei is because its nature and flavor, enters stomach, large intestine, liver footpath, has the poison that purges heat, and removing mass is stagnant, the function of clots absorbing blood, controls excess-heat constipation, Delirium is gone mad, food stagnation feeling of fullness, and dysentery is closed from the beginning of, tenesmus, stasis of blood menolipsis, and abdominal mass is gathered, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spit blood, Epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinate red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Olibanum to be because its nature and flavor to work hard, temperature, enter The heart, liver, spleen channel, have regulating qi and activating blood, analgesic therapy, chases after the function of poison, controls coagulation of QI-blood, trusted subordinate's pain, ulcerative carbuncle toxic swelling, traumatic injury, Dysmenorrhea, postnatal blood stasis twinge.Myrrha is selected to be because its nature and flavor bitter, flat, enter Liver Channel, have a scattered blood blood stasis removing, the function of subduing swelling and relieving pain, Control and fall damage, incised wound, muscles and bones, all pains of trusted subordinate, abdominal mass, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.Radix Dipsaci is selected to be because its nature and flavor bitter Pungent, tepor, enter liver, kidney channel, have invigorating the liver and kidney, reuniting the fractured tendons and bones, the function of blood circulation regulating, control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, Leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.Herba Taxilli is selected to be because its property bitter but sweet flavor, flat, enter liver, kidney Warp, has invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, benefit blood, antiabortive function, controls soreness of waist and knee joint, and muscles and bones flaccidity is weak, hemiplegia, foot Gas, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have Replenishing and activating blood, menstruction regulating and pain relieving, to moisturize the function of laxation, control menoxenia, amenorrhea is suffered from abdominal pain, and abdominal mass knot is poly-, metrorrhagia, headache due to deficiency of blood, Dizziness, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Rhizoma Et Radix Notopterygii to be because its nature and flavor to work hard, Temperature, enters bladder, kidney channel, has scattered exterior cold, wind-damp dispelling, and the function in profit joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape Muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.Select Radix Angelicae Pubescentis to be because its nature and flavor to work hard, temperature, enter kidney, bladder warp, dispel Wind, wins wet, cold expelling, the function of pain relieving, controls anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Choosing It is because its nature and flavor bitter with Cortex Phellodendri, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, bone Steam consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.The Cortex Eucommiae is selected to be because its nature and flavor sweet micro-pungent, temperature, enter liver, kidney channel, have Invigorating the liver and kidney, bone and muscle strengthening, antiabortive function, control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination itches, and vaginal bleeding during pregnancy is intended to fall, high blood Pressure.Select Rhizoma Atractylodis to be because its nature and flavor to work hard, temperature, enter spleen, stomach warp, have spleen invigorating, dampness, resolving depression, ward off dirty function, control wet Sheng and be stranded Spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, to have loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, wind and cold is wet Numbness, flaccidity of the lower limbs, nyctalopia.Rhizoma Alismatis is selected to be because its nature and flavor sweet, cold, enter bladder warp, have diuretic, eliminating dampness by diuresis, the function expelled the heat-evil, control urine Unfavorable, edema anus is full, vomiting, dysentery, phlegm retention, tinea pedis, gonorrhea, hematuria.Semen Coicis is selected to be because its property slightly sweet flavor, cool, enter Spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, control and have loose bowels, arthralgia chiefly caused by damp pathogen, muscle arteries and veins contracture, joint stuffiness, edema, foot Gas, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.Select Rhizoma Curcumae Longae to be because its nature and flavor to work hard, temperature, enter spleen, Liver Channel, have removing blood stasis, OK Gas, stimulates the menstrual flow, the function of pain relieving, controls trusted subordinate's feeling of fullness distending pain, brachialgia, abdominal mass, women's blood stasis amenorrhea, and puerperal, the stasis of blood stopped stomachache, falls and flutters damage Wound, carbuncle.Select Lignum Sappan to be because its nature and flavor sweet, salty, flat, have promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, the function of pain relieving, control married woman's vim and vigour heart Stomachache, amenorrhea, postnatal blood stasis, distending pain dyspnea with rapid respiration, dysentery, tetanus.Rhizoma Chuanxiong is selected to be because its nature and flavor pungent, temperature, enter liver, gallbladder meridian, Having activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache rotation dizzy, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult Produce, postpartum stagnation block pain, ulcer sores.
The consumption of drug component of the present invention be also inventor through substantial amounts of grope to sum up draw, the consumption of each component exists All there is in the range of following weight preferable curative effect.
Radix Clematidis 8-12 gram of Radix Aconiti Kusnezoffii of 10-20 gram of Radix Aconiti 8-12 gram
Radix Astragali 24-40 gram of Herba Lycopodii of 40-60 gram of Herba speranskiae tuberculatae 130-160 gram
Caulis Spatholobi 8-15 gram of Rhizoma Drynariae of 8-15 gram of Radix Saposhnikoviae 8-15 gram
8-15 gram of Ramulus Cinnamomi 40-60 0.1-0.45 gram of Flos Carthami of Rana nigromaculata Semen Strychni
Radix Cyathulae 10-20 gram of Olibanum of 15-25 gram of Radix Et Rhizoma Rhei 8-15 gram
Myrrha 15-25 gram of Herba Taxilli of 8-15 gram of Radix Dipsaci 8-15 gram
Radix Angelicae Sinensis 8-15 gram of Radix Angelicae Pubescentis of 25-35 gram of Rhizoma Et Radix Notopterygii 8-15 gram
8-15 gram of Cortex Eucommiae 15-25 gram Rhizoma Atractylodis of Cortex Phellodendri 8-15 gram
8-15 gram of Rhizoma Alismatis 8-15 gram of Rhizoma Curcumae Longae of 8-15 gram of Semen Coicis
8-15 gram of Rhizoma Chuanxiong of Lignum Sappan 8-15 gram
It is preferably
Radix Clematidis 10 grams of Radix Aconiti Kusnezoffiis of 15 grams of Radix Aconitis 10 grams
The Radix Astragali 30 grams of Herba Lycopodiis of 50 grams of Herba speranskiae tuberculataes 150 grams
Caulis Spatholobi 10 grams of Rhizoma Drynariae of 10 grams of Radix Saposhnikoviaes 10 grams
10 grams of 0.1 gram of Flos Carthami of Ramulus Cinnamomi 50 Rana nigromaculata Semen Strychni
Radix Cyathulae 15 grams of Olibanums of 20 grams of Radix Et Rhizoma Rhei 10 grams
Myrrha 20 grams of Herba Taxillis of 10 grams of Radix Dipsacis 10 grams
Radix Angelicae Sinensis 10 grams of Radix Angelicae Pubescentiss of 30 grams of Rhizoma Et Radix Notopterygiis 10 grams
Cortex Phellodendri 20 grams of Rhizoma Atractylodis of 10 grams of Cortexs Eucommiae 10 grams
10 grams of Rhizoma Alismatis 10 grams of Rhizoma Curcumae Longaes of 10 grams of Semen Coiciss
10 grams of Rhizoma Chuanxiongs of Lignum Sappan 10 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Clematidis: pick clean impurity, removes residual stem, is soaked in water, pull out and run through, and cutting is dried;
2, Radix Aconiti: pick decontamination, cleans ash bits, dries;
3, Radix Aconiti Kusnezoffii: take crude drug, removes impurity, cleaning, drying, and the used time smashs to pieces;
4, the Radix Astragali: pick clean impurity, removes the root head of residual and hollow bigger root, is soaked in water, pulls out, cut in time after running through Sheet, dries;
5, Herba speranskiae tuberculatae: pick clean impurity, cutting;
6, Herba Lycopodii: sieve dedusting bits, picks clean impurity, is cut into segment;
7, Caulis Spatholobi: run through with water, section, or steam soft after cut into slices while hot, dry;
8, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
9, Rhizoma Drynariae: remove sediment contamination, cleans, slightly soaks, run through, and section is dried;
10, Ramulus Cinnamomi: slightly soak with water, pulls out, and moistening, to thoroughly, is cut into slices, dried, sieve anti-dandruff;
11, Semen Strychni: take crude drug, removes impurity;
12, Flos Carthami: pick clean impurity, removes stem and leaf, base of a fruit head, dries;
13, Radix Cyathulae: pick decontamination, dries;
14, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity uniform, cuts into slices or be cut into small pieces, drying;
15, Olibanum: pick sand impurity;
16, Myrrha: pick decontamination, breaks into fragment;
17, Radix Dipsaci: clean silt, removes retained root head, and after running through, section is dried, and sieves anti-dandruff;
18, Herba Taxilli: wash, runs through, and cutting is dried;
19, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dry in the air to internal and external temperature suitable time, section, dry;
20, Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section is dried;
21, Radix Angelicae Pubescentis: pick decontamination, separately size, clean, and cuts into slices after running through, and is dried;
22, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, section or shredding, dries;
23, the Cortex Eucommiae: remove rough bark, cleans, runs through, dice or strand, dry;
24, Rhizoma Atractylodis: pick decontamination, with blister to seven, the most thoroughly, pull out, cut into slices, dry after running through;
25, Rhizoma Alismatis: pick decontamination, size stepping, is soaked in water to eighty per cant thoroughly, pulls out, shine cool, and moistening to inside and outside humidity is uniform, Section, dries;
26, Semen Coicis: take crude drug, removes residual cot, impurity;
27, Rhizoma Curcumae Longae: pick decontamination, is soaked in water, and picks up, and cuts into slices, dry after running through;
28, Lignum Sappan: take crude drug, is sawn into short section, then is split into fragment or pound sheet;
29, Rhizoma Chuanxiong: pick decontamination, is soaked in water by the most large and small, and solarization is dried in the air, and cuts into slices after moistening, is dried.
Two, preparation
1, the crude drug cooked is loaded in cloth bag;
2, the medicated bag installed is put in the electric food warmer of temp. controllable, add water 3000-3500 gram;
3, soak after 15 minutes, activate switch, cover pot cover heating, make heat up steam of emerging of medicinal liquid produce atomization, treat medicinal liquid temperature Degree reaches to be when 42 DEG C treatment temperature.
Knee osteoarthritis is the commonly encountered diseases that one kind of multiple factors cause, and belongs to traditional Chinese medical science rheumatism involving the bone category, and middle-aged and elderly people is common, with Articular cartilage damage, cartilage reactive hyperplasia are main pathological change, clinical with the slow expansionary gonalgia, deadlock just, swollen Swollen and functional activity is limited as mainly showing.At present doctor trained in Western medicine there is no preferable Therapeutic Method, takes Western medicine, forces on, dials tank etc. Can only alleviate pain at that time, arthropathy gradually increases the weight of deformity, and etiology and pathogenesis entirety belongs to weakened body resistance, Liver and kidney, deficiency of marrow-reservoir, and local Then belong to caused by blood stasis, cold coagulation more.Exopathogen strongly fragrant resistance meridians, QI-blood circulation is not smooth, then cause local swelling pain, movable unfavorable, treatment When to dispel the wind, cold expelling, dehumidifying, blood stasis dispelling, eliminating stagnation is principle."Nei Jing" cloud: " keep muscle at muscle, keep bone at bone." " pain is born in muscles and bones, That controls draws to smoke ", because primary disease disease position is muscles and bones, therefore method for the treatment of herb fumigation is just accord with this reason, uses Chinese medicine gas to treat, passes through medicine fuming Steaming penetrates into local patholoic change, makes effective ingredient pass through the space between skin and muscles through sick institute of power with warm of using pungent drugs for dispersion and bitter drugs for purgation.Medicine in this medicated bag Thing can alleviate Knee Adhesion, rich in nutrition, warming the meridian and promoting blood circulation, makes drug effect go directly knee joint, can stop joint more quickly and effectively The damage of cartilage, suppresses bone reactive hyperplasia, improves blood circulation, diminish inflammation, and gradually absorbs hyperplastic tissue, releases joint soft The stimulation of tissue and adhesion, reach to eliminate pain, recover the purpose of function of joint.
In prescription, Herba Lycopodii has expelling wind and cold, and dehumidifying detumescence, the function of relaxing muscles and tendons to promote blood circulation is monarch drug;Radix Aconiti, Radix Aconiti Kusnezoffii have Dissipating ailment said due to cold or exposure, dispelling cold and dampness, search wind prevailing over dampness, the function of reducing swelling and alleviating pain, the two is ministerial drug, and three taste medicines play expelling wind and cold jointly, dehumidifying Detumescence, relaxing muscles and tendons to promote blood circulation, the effect of expelling wind to alleviate pain, treatment osteoarthritis effect is comprehensive, and with expelling wind and cold, relaxing muscles and tendons to promote blood circulation is main Can effect a permanent cure;Herba Taxilli has invigorating the liver and kidney, bone and muscle strengthening, and except rheumatism, the function of the meridian dredging is adjuvant drug;Radix Cyathulae is dispeled the wind, dampness removing, logical Warp, the function invigorated blood circulation are for making medicine, and all medicines can take stopgap measures with being left.
The present invention is by said medicine and all medicines combination of being left so that each efficacy of drugs produces synergism such that it is able to have The recurrence of effect treatment knee joint osseous arthritis.
Medicine of the present invention has expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation, the kidney invigorating regulating QI, and analgesic therapy chases after the function of poison, is used for Treatment knee joint osseous arthritis good effect, cure rate is high, has no side effect.
Detailed description of the invention
The beneficial effect of of the present invention medicine is expanded on further below in conjunction with clinical trial example.
The crude drug cooked is put in cloth bag, the medicated bag installed is put in the electric heating pot of temp. controllable and add water 3000-3500 gram, after soaking 15 minutes, activate switch, cover pot cover heating, make medicinal liquid heat up emerge steam produce aerosol, treat When temperature reaches 42 DEG C, take the lid of the pot off, allow patient crouch on simple fumigation bed, make patient lies prone position, suffer from knee position and be placed on heating Fumigate on pot, control fluid temperature 40-45 DEG C, once a day, each each position 20 minutes, fumigate 6 times, after 6 times for every bag Medicine dressing change bag again, until symptom functional rehabilitation is normal.In 50 example patients, there are 10 bags of transference cures of 10 example patient treatment, 22 example patients Treating 15 bags of transference cures, 17 example patient treatment more than 30 bags transference cures, 1 example patient's abandoning cure, cure rate is 98%.Control During treatment, advise patient's move body posture, in order before first fumigation, medial surface, lateral surface, after, and each position 20 points Being gradually increased the fumigation time after clock fumigation 2 bags is respectively 30 minutes, more than 40 minutes to 60 minutes, makes the medicine of atomization in steamer Thing gas abundant fumigation affected part.

Claims (3)

1. the external used medicine treating knee joint osseous arthritis, it is characterised in that: it is former by following weight range Material medicine is made:
Radix Clematidis 8-12 gram of Radix Aconiti Kusnezoffii of 10-20 gram of Radix Aconiti 8-12 gram
Radix Astragali 24-40 gram of Herba Lycopodii of 40-60 gram of Herba speranskiae tuberculatae 130-160 gram
Caulis Spatholobi 8-15 gram of Rhizoma Drynariae of 8-15 gram of Radix Saposhnikoviae 8-15 gram
8-15 gram of Ramulus Cinnamomi 40-60 0.1-0.45 gram of Flos Carthami of Rana nigromaculata Semen Strychni
Radix Cyathulae 10-20 gram of Olibanum of 15-25 gram of Radix Et Rhizoma Rhei 8-15 gram
Myrrha 15-25 gram of Herba Taxilli of 8-15 gram of Radix Dipsaci 8-15 gram
Radix Angelicae Sinensis 8-15 gram of Radix Angelicae Pubescentis of 25-35 gram of Rhizoma Et Radix Notopterygii 8-15 gram
8-15 gram of Cortex Eucommiae 15-25 gram Rhizoma Atractylodis of Cortex Phellodendri 8-15 gram
8-15 gram of Rhizoma Alismatis 8-15 gram of Rhizoma Curcumae Longae of 8-15 gram of Semen Coicis
8-15 gram of Rhizoma Chuanxiong of Lignum Sappan 8-15 gram.
External used medicine the most according to claim 1, the consumption of the most each crude drug is:
Radix Clematidis 10 grams of Radix Aconiti Kusnezoffiis of 15 grams of Radix Aconitis 10 grams
The Radix Astragali 30 grams of Herba Lycopodiis of 50 grams of Herba speranskiae tuberculataes 150 grams
Caulis Spatholobi 10 grams of Rhizoma Drynariae of 10 grams of Radix Saposhnikoviaes 10 grams
10 grams of 0.1 gram of Flos Carthami of Ramulus Cinnamomi 50 Rana nigromaculata Semen Strychni
Radix Cyathulae 15 grams of Olibanums of 20 grams of Radix Et Rhizoma Rhei 10 grams
Myrrha 20 grams of Herba Taxillis of 10 grams of Radix Dipsacis 10 grams
Radix Angelicae Sinensis 10 grams of Radix Angelicae Pubescentiss of 30 grams of Rhizoma Et Radix Notopterygiis 10 grams
Cortex Phellodendri 20 grams of Rhizoma Atractylodis of 10 grams of Cortexs Eucommiae 10 grams
10 grams of Rhizoma Alismatis 10 grams of Rhizoma Curcumae Longaes of 10 grams of Semen Coiciss
10 grams of Rhizoma Chuanxiongs of Lignum Sappan 10 grams.
The preparation method of external used medicine the most according to claim 1 or claim 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Clematidis: pick clean impurity, removes residual stem, is soaked in water, pull out and run through, and cutting is dried;
(2) Radix Aconiti: pick decontamination, cleans ash bits, dries;
(3) Radix Aconiti Kusnezoffii: take crude drug, removes impurity, cleaning, drying, and the used time smashs to pieces;
(4) Radix Astragali: pick clean impurity, removes the root head of residual and hollow bigger root, is soaked in water, pulls out, cut in time after running through Sheet, dries;
(5) Herba speranskiae tuberculatae: pick clean impurity, cutting;
(6) Herba Lycopodii: sieve dedusting bits, picks clean impurity, is cut into segment;
(7) Caulis Spatholobi: run through with water, section, or steam soft after cut into slices while hot, dry;
(8) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(9) Rhizoma Drynariae: remove sediment contamination, cleans, slightly soaks, run through, and section is dried;
(10) Ramulus Cinnamomi: slightly soak with water, pulls out, and moistening, to thoroughly, is cut into slices, dried, sieve anti-dandruff;
(11) Semen Strychni: take crude drug, removes impurity;
(12) Flos Carthami: pick clean impurity, removes stem and leaf, base of a fruit head, dries;
(13) Radix Cyathulae: pick decontamination, dries;
(14) Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity uniform, cuts into slices or be cut into small pieces, drying;
(15) Olibanum: pick sand impurity;
(16) Myrrha: pick decontamination, breaks into fragment;
(17) Radix Dipsaci: clean silt, removes retained root head, and after running through, section is dried, and sieves anti-dandruff;
(18) Herba Taxilli: wash, runs through, and cutting is dried;
(19) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dry in the air to internal and external temperature suitable time, section, dry;
(20) Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section is dried;
(21) Radix Angelicae Pubescentis: pick decontamination, separately size, clean, and cuts into slices after running through, and is dried;
(22) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, section or shredding, dries;
(23) Cortex Eucommiae: remove rough bark, cleans, runs through, dice or strand, dry;
(24) Rhizoma Atractylodis: pick decontamination, with blister to seven, the most thoroughly, pull out, cut into slices, dry after running through;
(25) Rhizoma Alismatis: pick decontamination, size stepping, is soaked in water to eighty per cant thoroughly, pulls out, shine cool, and moistening to inside and outside humidity is uniform, Section, dries;
(26) Semen Coicis: take crude drug, removes residual cot, impurity;
(27) Rhizoma Curcumae Longae: pick decontamination, is soaked in water, and picks up, and cuts into slices, dry after running through;
(28) Lignum Sappan: take crude drug, is sawn into short section, then is split into fragment or pound sheet;
(29) Rhizoma Chuanxiong: pick decontamination, is soaked in water by the most large and small, and solarization is dried in the air, and cuts into slices after moistening, is dried;
(2) prepare
(1) crude drug cooked is loaded in cloth bag;
(2) medicated bag installed is put in the electric food warmer of temp. controllable, add water 3000-3500 gram;
(3) soak after 15 minutes, activate switch, cover pot cover heating, make heat up steam of emerging of medicinal liquid produce aerosol, treat medicinal liquid temperature Degree reaches to be when 42 DEG C treatment temperature.
CN201610541986.2A 2016-07-12 2016-07-12 External use medicine for treating knee osteoarthritis and preparation method thereof Pending CN106039220A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107007724A (en) * 2017-04-20 2017-08-04 安阳古方医药科技有限公司 A kind of Traditional Chinese medice healthy liquid and preparation method thereof
CN109172751A (en) * 2018-11-14 2019-01-11 山东中医药大学 A kind of knee osteoarthritis Chinese medicine, which restores, repairs liquid medicine and preparation method thereof
CN110742957A (en) * 2019-11-15 2020-02-04 张磊 Fumigating traditional Chinese medicine composition
CN110934968A (en) * 2019-12-04 2020-03-31 菏泽市圣医医疗科技有限公司 Traditional Chinese medicine composition for treating knee joint hyperplasia arthritis and preparation method thereof

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CN102813860A (en) * 2012-08-03 2012-12-12 丁洪亮 Plaster for treating rheumatoid bone diseases
CN105106832A (en) * 2015-08-22 2015-12-02 十堰德远科技开发有限公司 Obstinate arthralgia wine used for treating rheumatic and rheumatoid arthritis arthralgia and preparation method thereof
CN105396058A (en) * 2015-12-09 2016-03-16 李进龙 Drug for treatment of cervical spondylosis and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102813860A (en) * 2012-08-03 2012-12-12 丁洪亮 Plaster for treating rheumatoid bone diseases
CN105106832A (en) * 2015-08-22 2015-12-02 十堰德远科技开发有限公司 Obstinate arthralgia wine used for treating rheumatic and rheumatoid arthritis arthralgia and preparation method thereof
CN105396058A (en) * 2015-12-09 2016-03-16 李进龙 Drug for treatment of cervical spondylosis and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107007724A (en) * 2017-04-20 2017-08-04 安阳古方医药科技有限公司 A kind of Traditional Chinese medice healthy liquid and preparation method thereof
CN107007724B (en) * 2017-04-20 2020-04-14 安阳古方医药科技有限公司 A Chinese medicinal liquid for health protection, and its preparation method
CN109172751A (en) * 2018-11-14 2019-01-11 山东中医药大学 A kind of knee osteoarthritis Chinese medicine, which restores, repairs liquid medicine and preparation method thereof
CN109172751B (en) * 2018-11-14 2021-07-16 山东中医药大学 Traditional Chinese medicine rehabilitation and repair medicinal liquor for knee osteoarthritis and preparation method thereof
CN110742957A (en) * 2019-11-15 2020-02-04 张磊 Fumigating traditional Chinese medicine composition
CN110934968A (en) * 2019-12-04 2020-03-31 菏泽市圣医医疗科技有限公司 Traditional Chinese medicine composition for treating knee joint hyperplasia arthritis and preparation method thereof

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