CN103288890B - 一种制备3-O-苄基-1，2-O-异亚丙基-β-L-呋喃艾杜糖的新方法 - Google Patents

一种制备3-O-苄基-1，2-O-异亚丙基-β-L-呋喃艾杜糖的新方法 Download PDF

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Publication number
CN103288890B
CN103288890B CN201210050766.1A CN201210050766A CN103288890B CN 103288890 B CN103288890 B CN 103288890B CN 201210050766 A CN201210050766 A CN 201210050766A CN 103288890 B CN103288890 B CN 103288890B
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reaction
compound
preparation
hydroxide
basic conditions
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CN201210050766.1A
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Chinese (zh)
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CN103288890A (zh
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丁毅力
郭阳辉
白骅
何亮
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Zhejiang Hisun Pharmaceutical Co Ltd
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Zhejiang Hisun Pharmaceutical Co Ltd
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Priority to CN201210050766.1A priority Critical patent/CN103288890B/zh
Priority to JP2014557987A priority patent/JP2015508084A/ja
Priority to PCT/CN2013/071786 priority patent/WO2013123896A1/zh
Priority to EP13751650.6A priority patent/EP2818476A4/en
Priority to IN7656DEN2014 priority patent/IN2014DN07656A/en
Priority to US14/380,605 priority patent/US20150065700A1/en
Publication of CN103288890A publication Critical patent/CN103288890A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN201210050766.1A 2012-02-23 2012-02-23 一种制备3-O-苄基-1，2-O-异亚丙基-β-L-呋喃艾杜糖的新方法 Expired - Fee Related CN103288890B (zh)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN201210050766.1A CN103288890B (zh) 2012-02-23 2012-02-23 一种制备3-O-苄基-1，2-O-异亚丙基-β-L-呋喃艾杜糖的新方法
JP2014557987A JP2015508084A (ja) 2012-02-23 2013-02-22 ３−Ｏ−ベンジル−１，２−Ｏ−イソプロピリデン−α−Ｌ−イドフラノースの製造方法
PCT/CN2013/071786 WO2013123896A1 (zh) 2012-02-23 2013-02-22 一种制备3-O-苄基-1，2-O-异亚丙基-α-L-呋喃艾杜糖的方法
EP13751650.6A EP2818476A4 (en) 2012-02-23 2013-02-22 PROCESS FOR PREPARING 3-O-BENZYL-1,2-O-ISOPROPYLIDENE-L-FURANIDOSE
IN7656DEN2014 IN2014DN07656A (https=) 2012-02-23 2013-02-22
US14/380,605 US20150065700A1 (en) 2012-02-23 2013-02-22 Method for preparing 3-o-benzyl-1,2-o-isopropylidene-a-l-furan idose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210050766.1A CN103288890B (zh) 2012-02-23 2012-02-23 一种制备3-O-苄基-1，2-O-异亚丙基-β-L-呋喃艾杜糖的新方法

Publications (2)

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CN103288890A CN103288890A (zh) 2013-09-11
CN103288890B true CN103288890B (zh) 2016-09-14

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CN201210050766.1A Expired - Fee Related CN103288890B (zh) 2012-02-23 2012-02-23 一种制备3-O-苄基-1，2-O-异亚丙基-β-L-呋喃艾杜糖的新方法

Country Status (6)

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US (1) US20150065700A1 (https=)
EP (1) EP2818476A4 (https=)
JP (1) JP2015508084A (https=)
CN (1) CN103288890B (https=)
IN (1) IN2014DN07656A (https=)
WO (1) WO2013123896A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109438534B (zh) * 2018-11-16 2020-09-29 江苏美迪克化学品有限公司 一种磺达肝癸钠单糖中间体的合成方法
CN110577559B (zh) * 2019-08-19 2023-02-17 江西科技师范大学 α-L-艾杜糖醛酸酶测定用荧光糖苷酶底物的合成方法
CN111808149A (zh) * 2020-07-02 2020-10-23 浙江晟格生物科技有限公司 一种以单丙酮葡萄糖为原料制备l-艾杜糖的方法
CN113444752B (zh) * 2021-07-15 2023-06-23 南京工业大学 一种采用微通道反应器连续制备2-苄基异吲哚啉酮类化合物的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248779A (en) * 1991-06-17 1993-09-28 Monsanto Company Synthesis of nojirimycin derivatives
JPH07278172A (ja) * 1994-04-04 1995-10-24 Kao Corp ３−ｏ−アルキル−１，２−ｏ−イソプロピリデングルコフラノース、その製造方法及びそれを含有する化粧料
CN101228173A (zh) * 2005-06-08 2008-07-23 阿米库斯治疗学公司 三氟甲磺酸酯化的化合物的稳定化

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248779A (en) * 1991-06-17 1993-09-28 Monsanto Company Synthesis of nojirimycin derivatives
JPH07278172A (ja) * 1994-04-04 1995-10-24 Kao Corp ３−ｏ−アルキル−１，２−ｏ−イソプロピリデングルコフラノース、その製造方法及びそれを含有する化粧料
CN101228173A (zh) * 2005-06-08 2008-07-23 阿米库斯治疗学公司 三氟甲磺酸酯化的化合物的稳定化

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Practical synthesis of [1-13C]- and [6-13C]-D-galactose;Ken-ichi Sato等;《Tetrahedron Letters》;20031231;第44卷;4903–4907 *

Also Published As

Publication number Publication date
JP2015508084A (ja) 2015-03-16
IN2014DN07656A (https=) 2015-05-15
EP2818476A1 (en) 2014-12-31
CN103288890A (zh) 2013-09-11
US20150065700A1 (en) 2015-03-05
WO2013123896A1 (zh) 2013-08-29
EP2818476A4 (en) 2015-09-23

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