CN103251947A - 穿过上皮和/或内皮层的scFV抗体 - Google Patents
穿过上皮和/或内皮层的scFV抗体 Download PDFInfo
- Publication number
- CN103251947A CN103251947A CN2013101593870A CN201310159387A CN103251947A CN 103251947 A CN103251947 A CN 103251947A CN 2013101593870 A CN2013101593870 A CN 2013101593870A CN 201310159387 A CN201310159387 A CN 201310159387A CN 103251947 A CN103251947 A CN 103251947A
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- Prior art keywords
- antigen
- pharmaceutical composition
- antibody
- binding polypeptides
- polypeptide
- Prior art date
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Microbiology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
Claims (51)
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CN2007800314717A CN101505794B (zh) | 2006-07-10 | 2007-07-10 | 穿过上皮和/或内皮层的scFV抗体 |
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CN2007800314717A Division CN101505794B (zh) | 2006-07-10 | 2007-07-10 | 穿过上皮和/或内皮层的scFV抗体 |
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CN103251947A true CN103251947A (zh) | 2013-08-21 |
CN103251947B CN103251947B (zh) | 2017-11-21 |
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CN2007800314717A Active CN101505794B (zh) | 2006-07-10 | 2007-07-10 | 穿过上皮和/或内皮层的scFV抗体 |
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CN (2) | CN103251947B (zh) |
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SI (1) | SI2046382T1 (zh) |
WO (1) | WO2008006235A2 (zh) |
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CN102164958A (zh) * | 2008-06-25 | 2011-08-24 | 艾斯巴技术,爱尔康生物医药研究装置有限责任公司 | 使用通用抗体构架进行的兔抗体的人源化 |
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CN104800147A (zh) * | 2008-07-10 | 2015-07-29 | 德勒尼克斯治疗股份公司 | 用于大分子的增强的递送的方法和组合物 |
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US11269987B2 (en) | 2019-09-09 | 2022-03-08 | International Business Machines Corporation | Security credentials management for client applications |
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2007
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- 2007-07-10 HU HUE07763939A patent/HUE032654T2/en unknown
- 2007-07-10 LT LTEP07763939.1T patent/LT2046382T/lt unknown
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2015
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2017
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