CN103210308B - 源自生药的成分的定量方法 - Google Patents

源自生药的成分的定量方法 Download PDF

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Publication number
CN103210308B
CN103210308B CN201180054812.9A CN201180054812A CN103210308B CN 103210308 B CN103210308 B CN 103210308B CN 201180054812 A CN201180054812 A CN 201180054812A CN 103210308 B CN103210308 B CN 103210308B
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alcohol
solid phase
plasma
solution
water
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CN103210308A (zh
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铃木加代子
铃木恒阳
冢原路子
春田裕子
八田明
浜田雄二
井上秀雄
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Minophagen Pharmaceutical Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
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  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CN201180054812.9A 2010-11-16 2011-11-15 源自生药的成分的定量方法 Active CN103210308B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010-256187 2010-11-16
JP2010256187A JP5193266B2 (ja) 2010-11-16 2010-11-16 生薬由来成分の高感度定量方法
PCT/JP2011/076248 WO2012067090A1 (ja) 2010-11-16 2011-11-15 生薬由来成分の高感度定量方法

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CN103210308A CN103210308A (zh) 2013-07-17
CN103210308B true CN103210308B (zh) 2015-01-07

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JP (1) JP5193266B2 (enExample)
KR (1) KR101476144B1 (enExample)
CN (1) CN103210308B (enExample)
RU (1) RU2558042C2 (enExample)
WO (1) WO2012067090A1 (enExample)

Families Citing this family (7)

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RU2603363C1 (ru) * 2015-09-23 2016-11-27 федеральное государственное бюджетное образовательное учреждение высшего образования "Новосибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО НГМУ Минздрава России) Вольтамперометрический способ количественного определения глицирризиновой кислоты в фармацевтических субстанциях
KR102617148B1 (ko) * 2016-08-15 2023-12-26 제넨테크, 인크. 비이온성 계면활성제 및 폴리펩티드를 포함하는 조성물에서 비이온성 계면활성제를 정량화하기 위한 크로마토그래피 방법
CN107064327A (zh) * 2016-12-23 2017-08-18 东北制药集团沈阳第制药有限公司 一种检测复方甘草片中吗啡和甘草酸含量的方法
JP7019372B2 (ja) * 2017-10-19 2022-02-15 株式会社あすか製薬メディカル ビタミンｄ代謝物の選択的測定法
RU2700831C1 (ru) * 2019-01-24 2019-09-23 Федеральное государственное бюджетное учреждение "Научный центр экспертизы средств медицинского применения" Министерства здравоохранения Российской Федерации (ФГБУ "НЦЭСМП" Минздрава России) Способ количественного определения глицина в биологических лекарственных препаратах методом гидрофильной высокоэффективной жидкостной хроматографии
JP7479633B2 (ja) 2020-12-03 2024-05-09 株式会社ツムラ アンバムの分析方法
CN113984916B (zh) * 2021-09-28 2024-04-19 天津中医药大学第一附属医院 一种正髓丸及正髓丸药材含量测定方法

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US20050148088A1 (en) * 2002-04-19 2005-07-07 Eng Shi Ong Pressurized hot water extraction
CN101216465A (zh) * 2007-12-28 2008-07-09 北京联合大学生物化学工程学院 甘草药材指纹图谱的建立方法及其标准指纹图谱
CN101532994A (zh) * 2009-04-18 2009-09-16 姚俊华 健脑补肾制剂的含量测定方法
CN101897680A (zh) * 2009-06-01 2010-12-01 天津药物研究院 液体胶囊制剂、其制备方法及用途

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WO2008109632A1 (en) * 2007-03-07 2008-09-12 Sanofi-Aventis U.S. Llc The quantitative determination of risedronate in urine by spe-lc-ms-ms

Patent Citations (4)

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US20050148088A1 (en) * 2002-04-19 2005-07-07 Eng Shi Ong Pressurized hot water extraction
CN101216465A (zh) * 2007-12-28 2008-07-09 北京联合大学生物化学工程学院 甘草药材指纹图谱的建立方法及其标准指纹图谱
CN101532994A (zh) * 2009-04-18 2009-09-16 姚俊华 健脑补肾制剂的含量测定方法
CN101897680A (zh) * 2009-06-01 2010-12-01 天津药物研究院 液体胶囊制剂、其制备方法及用途

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Determination of glycyrrhetic acid in human plasma by HPLC-MS method and investigation of its pharmacokinetics;W.-J. Zhao PhD et al;《Journal of Clinical Pharmacy and Therapeutics》;20080630;第33卷(第3期);第289-294页 *
Determination of glycyrrhetic acid in human plasma by LC-ESI-MS;Li Ding et al;《Journal of Pharmaceutical and Biomedical Analysis》;20060224;第40卷(第3期);第758-762页 *
HPLC-MS-MS测定人血浆中的甘草次酸及生物利用度;田娟 等;《中南药学》;20070920;第5卷(第5期);第475-478页 *
Simultaneous determination of glycyrrhizin, a marker component in radix Glycyrrhizae, and its major metabolite glycyrrhetic acid in human plasma by LC-MS/MS;Zhongping John Lin et al;《Journal of Chromatography B》;20050125;第814卷(第2期);第201-207页 *
一般用医薬品の鎮咳去痰薬に含有される生薬の確認試験;瀬戸隆子 等;《東京健安研セ年報》;20041231;第55卷;第37-42页 *
生物样品中甘草酸及其代谢产物检测方法的研究进展;田莉 等;《药物分析杂志》;20090228;第29卷(第2期);第340-345页 *
赵文静 等.高效液相色谱-质谱法测定人血浆中甘草次酸浓度及人体药代动力学研究.《山东大学学报(医学版)》.2008,第46卷(第11期), *
食品に残留する農薬、飼料添加物又は動物用医薬品の成分である物質の試験法の一部改正について;厚生労働省医薬食品局食品安全部長通知;《食安発0802第2号》;20100802 *

Also Published As

Publication number Publication date
KR20130076892A (ko) 2013-07-08
WO2012067090A1 (ja) 2012-05-24
KR101476144B1 (ko) 2014-12-24
JP2012107954A (ja) 2012-06-07
CN103210308A (zh) 2013-07-17
JP5193266B2 (ja) 2013-05-08
RU2013125221A (ru) 2014-12-10
RU2558042C2 (ru) 2015-07-27

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