CN103201386A - 皮肤穿透及细胞进入(space)肽及其使用方法 - Google Patents

皮肤穿透及细胞进入(space)肽及其使用方法 Download PDF

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CN103201386A
CN103201386A CN2011800532510A CN201180053251A CN103201386A CN 103201386 A CN103201386 A CN 103201386A CN 2011800532510 A CN2011800532510 A CN 2011800532510A CN 201180053251 A CN201180053251 A CN 201180053251A CN 103201386 A CN103201386 A CN 103201386A
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seq
composition
peptide
sirna
penetrating
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T·徐
S·M·密特拉戈特里
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University of California San Diego UCSD
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    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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CN2011800532510A 2010-11-09 2011-10-05 皮肤穿透及细胞进入(space)肽及其使用方法 Pending CN103201386A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US41188410P 2010-11-09 2010-11-09
US61/411,884 2010-11-09
US201161527574P 2011-08-25 2011-08-25
US61/527,574 2011-08-25
US201161528036P 2011-08-26 2011-08-26
US61/528,036 2011-08-26
PCT/US2011/054967 WO2012064429A2 (en) 2010-11-09 2011-10-05 Skin permeating and cell entering (space) peptides and methods of use thereof

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CN103201386A true CN103201386A (zh) 2013-07-10

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US (4) US8518871B2 (cg-RX-API-DMAC7.html)
EP (1) EP2638162B1 (cg-RX-API-DMAC7.html)
JP (1) JP2014500867A (cg-RX-API-DMAC7.html)
KR (1) KR20130139254A (cg-RX-API-DMAC7.html)
CN (1) CN103201386A (cg-RX-API-DMAC7.html)
AU (1) AU2011326732B2 (cg-RX-API-DMAC7.html)
CA (1) CA2811113A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012064429A2 (cg-RX-API-DMAC7.html)

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CN105491982A (zh) * 2013-08-12 2016-04-13 3M创新有限公司 用于增强透皮递送的肽
CN105504066A (zh) * 2016-01-16 2016-04-20 广州市科玮生物技术有限公司 一种融合蛋白在化妆品中的应用
CN111803652A (zh) * 2020-08-04 2020-10-23 北京瀚梅生物科技有限公司 治疗痤疮的化合物在制备治疗痤疮的药物组合物或化妆品组合物中的用途
CN113943778A (zh) * 2020-07-17 2022-01-18 通用电气医疗集团股份有限公司 用于核酸检测的分子探针及其制备方法和用途
CN114315960A (zh) * 2021-12-31 2022-04-12 深圳市维琪医药研发有限公司 一种经修饰的肽及其美容组合物或药用组合物和用途

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HK1208361A1 (en) * 2012-05-16 2016-03-04 Aadigen, Llc Multi-target modulation for treating fibrosis and inflammatory conditions
KR101329411B1 (ko) 2012-05-31 2013-11-14 주식회사 엘지생활건강 피부투과성 펩타이드
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CN103897043A (zh) * 2012-12-28 2014-07-02 天津药物研究院 一种穿膜多肽连接拉帕替尼的制备及应用
US20140227174A1 (en) * 2013-02-11 2014-08-14 The Regents Of The University Of California Skin permeating and cell entering (space) peptides and methods of use therefor
WO2014123543A2 (en) * 2013-02-11 2014-08-14 Convoy Therapeutics Skin permeating and cell entering (space) peptides and methods of use therefor
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JP2016538829A (ja) 2013-10-03 2016-12-15 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 低密度リポタンパク質受容体をコードするポリヌクレオチド
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WO2016048246A1 (en) 2014-09-25 2016-03-31 Nanyang Technological University Targeting of melanocytes for delivering therapeutic or diagnostic agents using protein nanocages
WO2016071814A1 (en) 2014-11-04 2016-05-12 Università Degli Studi Di Milano A promoter for cutaneous absorption of active ingredients having peptidic structure
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
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WO2017043920A1 (ko) * 2015-09-10 2017-03-16 한양대학교 산학협력단 피부 투과성 펩티드 및 그 이용방법
WO2017048812A1 (en) * 2015-09-15 2017-03-23 The Regents Of The University Of California Skin-penetrating peptides and compositions and methods of use thereof
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
MX2018005146A (es) 2015-10-30 2018-08-23 Bonac Corp Composicion que contiene de manera estable molecula de acido nucleico de un solo filamento que suprime la expresion de gen tgf-b1.
WO2017082690A1 (ko) * 2015-11-12 2017-05-18 주식회사 펩트론 미백, 피부 탄력, 주름 개선 및 상처치유 활성을 갖는 다기능성 피부투과 펩타이드
WO2017120322A1 (en) 2016-01-05 2017-07-13 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
EP3405151A4 (en) * 2016-01-23 2019-09-11 Ampersand Biopharmaceuticals Inc. IMPROVED TRANSDERMAL DISTRIBUTION OF ACTIVE SUBSTANCES
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