CN103181564A - 用于免疫疾病的营养组合物 - Google Patents
用于免疫疾病的营养组合物 Download PDFInfo
- Publication number
- CN103181564A CN103181564A CN2013100726216A CN201310072621A CN103181564A CN 103181564 A CN103181564 A CN 103181564A CN 2013100726216 A CN2013100726216 A CN 2013100726216A CN 201310072621 A CN201310072621 A CN 201310072621A CN 103181564 A CN103181564 A CN 103181564A
- Authority
- CN
- China
- Prior art keywords
- vitamin
- composition
- calcium
- nutrients
- mineral matter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 92
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 16
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 20
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 20
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 20
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 20
- 230000002265 prevention Effects 0.000 claims abstract description 14
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 10
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 10
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 10
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 10
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims abstract description 10
- 229960000304 folic acid Drugs 0.000 claims abstract description 10
- 235000019152 folic acid Nutrition 0.000 claims abstract description 10
- 239000011724 folic acid Substances 0.000 claims abstract description 10
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 10
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000019158 vitamin B6 Nutrition 0.000 claims abstract description 10
- 239000011726 vitamin B6 Substances 0.000 claims abstract description 10
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 10
- 239000011718 vitamin C Substances 0.000 claims abstract description 10
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 10
- 239000011709 vitamin E Substances 0.000 claims abstract description 10
- 229940046009 vitamin E Drugs 0.000 claims abstract description 10
- 229940011671 vitamin b6 Drugs 0.000 claims abstract description 10
- 239000011701 zinc Substances 0.000 claims abstract description 10
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 10
- 241000186660 Lactobacillus Species 0.000 claims abstract description 9
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 9
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 8
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000010949 copper Substances 0.000 claims abstract description 8
- 229910052802 copper Inorganic materials 0.000 claims abstract description 8
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000011669 selenium Substances 0.000 claims abstract description 8
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 8
- 229920001202 Inulin Polymers 0.000 claims abstract description 7
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims abstract description 7
- 229940029339 inulin Drugs 0.000 claims abstract description 7
- 239000006041 probiotic Substances 0.000 claims abstract description 7
- 230000000529 probiotic effect Effects 0.000 claims abstract description 7
- 235000018291 probiotics Nutrition 0.000 claims abstract description 7
- 241000894006 Bacteria Species 0.000 claims abstract description 4
- 239000003814 drug Substances 0.000 claims abstract description 4
- 235000013376 functional food Nutrition 0.000 claims abstract description 4
- 239000004310 lactic acid Substances 0.000 claims abstract description 4
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 4
- 235000015097 nutrients Nutrition 0.000 claims description 23
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 18
- 239000011707 mineral Substances 0.000 claims description 18
- 235000010755 mineral Nutrition 0.000 claims description 18
- 208000026278 immune system disease Diseases 0.000 claims description 15
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 13
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 12
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 12
- 235000018102 proteins Nutrition 0.000 claims description 12
- 108090000623 proteins and genes Proteins 0.000 claims description 12
- 102000004169 proteins and genes Human genes 0.000 claims description 12
- 239000011575 calcium Substances 0.000 claims description 11
- 229910052791 calcium Inorganic materials 0.000 claims description 11
- 235000019197 fats Nutrition 0.000 claims description 10
- 235000013336 milk Nutrition 0.000 claims description 9
- 239000008267 milk Substances 0.000 claims description 9
- 210000004080 milk Anatomy 0.000 claims description 9
- 235000000346 sugar Nutrition 0.000 claims description 8
- 150000001720 carbohydrates Chemical class 0.000 claims description 7
- 235000014633 carbohydrates Nutrition 0.000 claims description 7
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 6
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 6
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 6
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 6
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 6
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 6
- 229930003451 Vitamin B1 Natural products 0.000 claims description 6
- 229930003471 Vitamin B2 Natural products 0.000 claims description 6
- 229930003316 Vitamin D Natural products 0.000 claims description 6
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 6
- 229910052742 iron Inorganic materials 0.000 claims description 6
- 239000011777 magnesium Substances 0.000 claims description 6
- 229910052749 magnesium Inorganic materials 0.000 claims description 6
- 235000001968 nicotinic acid Nutrition 0.000 claims description 6
- 229960003512 nicotinic acid Drugs 0.000 claims description 6
- 239000011664 nicotinic acid Substances 0.000 claims description 6
- 239000011574 phosphorus Substances 0.000 claims description 6
- 229910052698 phosphorus Inorganic materials 0.000 claims description 6
- 229960002477 riboflavin Drugs 0.000 claims description 6
- 229960003495 thiamine Drugs 0.000 claims description 6
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 6
- 235000019155 vitamin A Nutrition 0.000 claims description 6
- 239000011719 vitamin A Substances 0.000 claims description 6
- 235000010374 vitamin B1 Nutrition 0.000 claims description 6
- 239000011691 vitamin B1 Substances 0.000 claims description 6
- 235000019164 vitamin B2 Nutrition 0.000 claims description 6
- 239000011716 vitamin B2 Substances 0.000 claims description 6
- 235000019166 vitamin D Nutrition 0.000 claims description 6
- 239000011710 vitamin D Substances 0.000 claims description 6
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 6
- 229940045997 vitamin a Drugs 0.000 claims description 6
- 229940046008 vitamin d Drugs 0.000 claims description 6
- 229960003284 iron Drugs 0.000 claims description 4
- 229940091250 magnesium supplement Drugs 0.000 claims description 4
- 229920000084 Gum arabic Polymers 0.000 claims description 3
- 235000010489 acacia gum Nutrition 0.000 claims description 3
- 239000000205 acacia gum Substances 0.000 claims description 3
- 241000186605 Lactobacillus paracasei Species 0.000 claims 1
- 241000978776 Senegalia senegal Species 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 229930003779 Vitamin B12 Natural products 0.000 abstract 2
- 235000019163 vitamin B12 Nutrition 0.000 abstract 2
- 239000011715 vitamin B12 Substances 0.000 abstract 2
- 230000008901 benefit Effects 0.000 description 6
- 230000032683 aging Effects 0.000 description 5
- 230000003203 everyday effect Effects 0.000 description 5
- 230000035764 nutrition Effects 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 235000013361 beverage Nutrition 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000004054 inflammatory process Effects 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 208000017667 Chronic Disease Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 235000013351 cheese Nutrition 0.000 description 3
- 235000013325 dietary fiber Nutrition 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 235000008935 nutritious Nutrition 0.000 description 3
- 244000215068 Acacia senegal Species 0.000 description 2
- 208000007882 Gastritis Diseases 0.000 description 2
- 235000019484 Rapeseed oil Nutrition 0.000 description 2
- 206010067470 Rotavirus infection Diseases 0.000 description 2
- 108010073771 Soybean Proteins Proteins 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 235000008504 concentrate Nutrition 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 235000019710 soybean protein Nutrition 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 108010076119 Caseins Proteins 0.000 description 1
- 206010012742 Diarrhoea infectious Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000037487 Endotoxemia Diseases 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 102000004407 Lactalbumin Human genes 0.000 description 1
- 108090000942 Lactalbumin Proteins 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 208000012868 Overgrowth Diseases 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 108010084695 Pea Proteins Proteins 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 241000702670 Rotavirus Species 0.000 description 1
- 235000019485 Safflower oil Nutrition 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000021120 animal protein Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000015496 breakfast cereal Nutrition 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000021185 dessert Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N ferric oxide Chemical compound O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000021312 gluten Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 150000002617 leukotrienes Chemical class 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
- 150000002632 lipids Chemical group 0.000 description 1
- 230000003050 macronutrient Effects 0.000 description 1
- 235000021073 macronutrients Nutrition 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000006680 metabolic alteration Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000011785 micronutrient Substances 0.000 description 1
- 235000013369 micronutrients Nutrition 0.000 description 1
- LPUQAYUQRXPFSQ-DFWYDOINSA-M monosodium L-glutamate Chemical compound [Na+].[O-]C(=O)[C@@H](N)CCC(O)=O LPUQAYUQRXPFSQ-DFWYDOINSA-M 0.000 description 1
- 235000013923 monosodium glutamate Nutrition 0.000 description 1
- 239000004223 monosodium glutamate Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 235000019702 pea protein Nutrition 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 235000021085 polyunsaturated fats Nutrition 0.000 description 1
- 239000000955 prescription drug Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000021003 saturated fats Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 235000021262 sour milk Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000009923 sugaring Methods 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 235000021081 unsaturated fats Nutrition 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000013618 yogurt Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
- A23C9/1307—Milk products or derivatives; Fruit or vegetable juices; Sugars, sugar alcohols, sweeteners; Oligosaccharides; Organic acids or salts thereof or acidifying agents; Flavours, dyes or pigments; Inert or aerosol gases; Carbonation methods
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
- A23C9/1322—Inorganic compounds; Minerals, including organic salts thereof, oligo-elements; Amino-acids, peptides, protein-hydrolysates or derivatives; Nucleic acids or derivatives; Yeast extract or autolysate; Vitamins; Antibiotics; Bacteriocins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/065—Microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/244—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from corms, tubers or roots, e.g. glucomannan
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Rheumatology (AREA)
- Dispersion Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
Abstract
描述了一种用于预防或治疗免疫疾病的营养组合物,它包含至少维生素E,维生素C,维生素B6,叶酸,维生素B12,铜,锌,硒,果糖-低聚糖和/或菊粉,益生乳酸菌。例如在一个实施方案中,每300g该组合物包含维生素E150IU,维生素C120mg,维生素B62mg,叶酸400ug,维生素B123.8mg,铜1.5mg,锌15mg,硒100ug,果糖-低聚糖和/或菊粉3g,乳酸菌ST111010cfu。制备该组合物的方法,该组合物在生产用于预防或治疗免疫疾病的功能性食品或药剂的用途,以及一种治疗免疫疾病的方法,该方法包括服用有效量的该组合物。
Description
本案是分案申请,其母案是申请日为2001年11月14日、申请号为01818895.8、发明名称为“用于免疫疾病的营养组合物”的申请。
技术领域
本发明涉及一种用于预防或治疗免疫疾病的营养组合物,制备该组合物的方法,该组合物在生产用于预防或治疗免疫疾病的功能性食品或药剂的用途,以及一种治疗免疫疾病的方法,该方法包括服用有效量的该组合物。
背景技术
在本说明书的上下文中,术语“包含”是指“在其它东西中包括”,并不局限于“仅由......组成”。
在本说明书的上下文中,术语“免疫疾病”是指一种疾病,选自免疫应答减弱、炎症、发炎、慢性病(例如关节炎或胃炎)、与老化并导致炎症反应增加相关的疾病。
在19世纪末20世纪初,65岁以上的美国人总计占美国人口的4%,近年来他们总计占美国人口的12%以上。尽管他们只占美国人口的12%,但是他们却占每日住院患者的40%以上,购买总处方药物的30%以上并且消耗美国健康预算的30%。此外,预计在2030年,7千万以上的美国人(1∶5)将超过65岁,并且85岁以上的将在整个年龄组中占很大比例。
随着人口平均年龄的增加,可以预计与人口老化相关的营养需求和治疗将大大增加。许多生理功能的衰减将贯穿人的整个生命并且对营养学有所影响。例如,功能细胞数量的减少以及所导致的代谢过程减缓会使老年人的热量需求下降。同时随着年龄老化,通常身体机能降低,这进一步减少了能量需求。对于老年患者,仅仅减少总热量摄入可能会相反地影响他们所需要的营养。当总热量摄入量减少时,摄入的食物必需仔细确保蛋白质、维生素和矿物质的适当平衡摄入量。为了减少老年人的热量摄入,可以减少“空”热量(即脂肪)的摄入而增加营养密集食品的摄入(即碳水化合物和蛋白质)。
尽管健康成年人的营养需求不同于患病成年人的营养需求,但标准的营养配方是目前使用的基础营养物的主要形式。显然标准配方并不考虑老年患者的营养需求。标准产品的问题在于它们必需补充主要的微量营养物以补偿老年患者的常见缺乏和代谢变化。因此,需要一种符合老年患者营养需求的营养组合物。
除上述问题之外,需要一种解决老年人以及临床和治疗过程中的免疫疾病问题的组合物,例如有关运动损伤恢复方面。
此外,已知饮食和营养补充剂在改善生命质量方面可以起到很重要的作用。具体地说就是需要一种可以帮助改善健康,特别是有关免疫疾病的营养组合物。
此外,已知免疫应答减弱的问题可以与老化、慢性疾病和/或营养不良有关。此问题已经通过提供营养补充剂而得到部分的解决。但是这些补充剂的问题在于它们通常是具体针对某种疾病并且对于患有更复杂的综合疾病的患者来说,不会提供良好的营养支持。而这种情况特别与老年患者相关。此外,随着年龄老化,患有慢性病如关节炎、胃炎等的可能性增加,这会导致炎症反应的增加。
此外,需要一种营养组合物以解决与传染性腹泻(轮状病毒和细菌感染)、过敏、肠道完整的恢复和保持、细菌过度生长、内毒素性血症和肠道渗透性相关的问题。
本发明解决了上述问题。
发明内容
明显地现在已经发现了一种可以用于为老年患者提供营养、以及为例如运动员提供恢复营养、或为住院患者提供临床营养的组合物。
因此,本发明的第一个方面是提供一种组合物,它包含蛋白质源、碳水化合物源、脂肪源、益生乳酸菌和另外的果糖-低聚糖和/或菊粉。
本发明的第二个方面是提供一种制备根据本发明实施方案的组合物的方法,包括将所需营养物按照所需量混合在一起的步骤。
本发明的第三个方面是提供根据本发明的组合物在预防或治疗免疫疾病方面的用途。
本发明的第四个方面是提供根据本发明实施方案的组合物在生产用于预防或治疗免疫疾病的功能性食品或药剂的用途。
本发明的第五个方面是提供一种预防或治疗免疫疾病的方法,包括服用有效量的根据本发明实施方案的组合物。
根据本发明的组合物的一个优选实施方案包含一种或多种营养物或矿物质,选自维生素E,维生素C,维生素B6,叶酸,维生素B12,铜,锌和硒。更优选地,它包含至少两种这些营养物或矿物质。甚至更优选地,它包含至少三种这些营养物或矿物质。最优选的是它包括所有这些营养物或矿物质。
根据本发明的组合物的一个优选实施方案此外还包含一种或多种营养物或矿物质,选自钙,磷,镁,铁,维生素A,维生素B1,维生素B2,烟酸和维生素D。更优选地,它包含至少两种这些营养物或矿物质。甚至更优选地,它包含至少三种这些营养物或矿物质。根据本发明的组合物的一个最优选实施方案包括所有这些营养物或矿物质。
根据本发明的组合物的一个优选实施方案包含奶钙形式或衍生自奶钙形式的钙。
根据本发明的组合物的一个优选实施方案包含一种或多种益生乳酸菌,选自类干酪和约氏乳杆菌。根据本发明的组合物的一个更优选实施方案包含一种或多种益生乳酸菌,选自ST11(保藏号CNCMI-2116)和La1(保藏号CNCMI-1225)。
根据本发明的组合物的一个优选实施方案,每300g组合物包含下列质量或重量的营养物或矿物质(如果存在)。优选地,这是组合物的每日服用量。
维生素E:优选约1IU-约400IU,最优选约120IU,
维生素C:优选约6mg-约300mg,最优选约120mg,
维生素B6:优选约0.17mg-约3mg,最优选约2mg,
叶酸:优选约40ug-约800ug,最优选约400ug,
维生素B12:优选约0.24mg-约5mg,最优选约3.8ug,
铜:优选约0.3mg-约3mg,最优选约1.5mg,
锌:优选约1.5mg-约15mg,最优选约15mg,
硒:优选约7ug-约300ug,最优选约100ug,
果糖-低聚糖和/或阿拉伯树胶:优选约4g-约50g,最优选约6g,
乳酸菌:优选约108-约1012cfu,最优选约1010cfu。
根据本发明的组合物的一个优选实施方案,每300g组合物包含一种或多种营养物,选自下列质量或重量的营养物或矿物质(如果存在)。优选地,这是组合物的每日服用量。
钙:约100mg-约300mg,更优选约200mg;
磷:约50mg-约615mg,更优选约150mg;
镁:约110mg-约210mg,更优选约60mg;
维生素A:约1000IU-约1500IU,更优选约1333IU;
维生素D:约50IU-约150IU,更优选约100IU;
维生素E:约5.0IU-约150IU,更优选约120IU;
维生素C:约30mg-约500mg,更优选约120mg;
维生素B1:约0.1mg-约2mg,更优选约0.25mg;
维生素B2:约0.1mg-约0.6mg,更优选约0.3mg;
烟酸:约1.5mg-约7.2mg,更优选约3mg;
维生素B6:约1.0mg-约3.0mg,更优选约2mg;
叶酸:约200ug-约600ug,更优选约400ug;
维生素B12:约1.5ug-约4.5ug,更优选约3.8ug;
铁:约2.0mg-约5mg,更优选约2.75mg;
和锌:约10mg-约20mg,更优选约15mg。
根据本发明的组合物的一个优选实施方案包含阿拉伯树胶。
根据本发明的方法的一个优选实施方案包括将营养物按照所需量混合并将混合物挤出的步骤。更优选包括将混合物喷雾干燥。
本发明的一个优点是它提供了一种可以迅速溶解于水中形成饮料或汤的营养组合物。它不需要烹调。
本发明的另一个优点是它提供了一种可以简单地以食品方式使用和服用以预防或治疗免疫疾病的单一组合物。该组合物可以用于临床或恢复性治疗,并且特别适用于老年患者。
由益生菌提供的优点包括预防或抑制因病原菌引起的腹泻;预防或抑制特别是由轮状病毒感染肠内细胞而引起的腹泻;预防因病原菌引起的腹泻而导致的肠移生;和粘附并保护宿主生物体的肠内黏膜的能力。
本发明的另一个优点是它提供了一种对糖尿病患者有益的组合物。这是由于该特定的组合物包含的大量营养素、蛋白质、碳水化合物和脂肪提供了低糖指数。
本发明的其它特点和优点将描述于以下优选的实施方案中,并因此而更加明确。
出于清楚和简明描述的目的,在此所描述的特点作为部分相同或单独的实施方案,但是应该理解本发明的范围可以包括上述所有或某些特点的组合的实施方案。
在一个实施方案中,营养组合物包含蛋白质源。该蛋白质源优选提供营养配方能量的约5%-约55%;例如约20%-约50%,优选能量的26%。食用蛋白质优选作为蛋白质源。食用蛋白质可以是任何合适的食用蛋白质;例如动物蛋白质(如奶蛋白,肉蛋白或蛋蛋白);植物蛋白质(如大豆蛋白,小麦蛋白,大米蛋白,和豌豆蛋白);游离氨基酸的混合物;或其组合。特别优选奶蛋白如酪蛋白、乳清蛋白和大豆蛋白。
组合物还包含碳水化合物源和脂肪源。
脂肪源优选提供营养配方能量的约5%-约55%;例如约20%-约50%,优选能量的23%。脂质形成的脂肪源可以是任何合适的脂肪或脂肪混合物。植物脂肪是特别合适的;例如大豆油、棕榈油、椰子油、红花油、向日葵油、玉米油、菜籽油、卵磷脂等。最优选它是菜籽油和大豆油的混合物。如果需要,动物脂肪如奶脂肪也可以加入。
优选组合物包含饱和脂肪,它优选占产品总能量的约1%-约5%,更优选2.5%。优选组合物包含单不饱和脂肪,它优选占产品总能量的约5%-约15%,更优选9.9%。优选组合物包含多不饱和脂肪,它优选占产品总能量的约5%-约15%,更优选10.1%。优选组合物包含亚油酸,它优选占产品总能量的约5%-约15%,更优选8.5%。优选组合物包含亚麻酸,它优选占产品总能量的约0.5%-约5%,更优选1.6%。优选亚油酸和亚麻酸的比例为约3-约8,更优选约5.3。
碳水化合物源优选提供营养组合物能量的约40%-约80%,更优选约51%。可以使用任何合适的碳水化合物,例如蔗糖、乳糖、葡萄糖、果糖、玉米糖浆固体、麦芽糖糊精或其混合物。
组合物的该实施方案中,每300g组合物还包含约1010cfu的类干酪或约氏益生乳酸菌和约6g果糖-低聚糖和菊粉。
还可以加入食用纤维。优选食用纤维提供营养组合物能量的最多约5%。食用纤维可以来自任何合适的来源,优选果糖-低聚糖、菊粉或其混合物。
此外合适的维生素和矿物质可以包括在上述组合物中。
谷氨酸单钠可以作为调味剂加入。
营养组合物优选是可内服的;例如粉末、浓缩液、或即饮饮料的形式。如果希望生产粉末营养制剂,则将均匀的混合物置于合适的干燥设备如喷雾干燥器或冷冻干燥器中并转化为粉末。
此外,常见的食品中可以加入该组合物的实施方案。例如酸奶、酸乳酪、新鲜乳酪、凝乳、糖果制品,例如甜或加糖的饮料、糖棒、早餐谷物薄片或棒、饮料、奶粉、豆类制品、非牛奶类的发酵制品或用于临床的营养补充剂。该组合物的加入量优选至少约0.01重量%。
仅以说明的目的给出下列实施例,而不应该理解为限制本发明的范围。除非另有说明,否则百分数和份数均以重量计。
具体实施方式
实施例
实施例1和2:营养组合物
通过混合所需组分来制备两种营养组合物。其组成如下表1所示。组合物的形式为两种每日口服的基于饮料浓缩液的补充剂或奶制品甜点。每日总剂量大约为300g或300ml该组合物。
表1
应该理解对于本领域的技术人员而言,对本文所述的优选实施方案进行各种变动和更改将是显而易见的。
可以作出这些变动和更改而不背离本发明的精神和范围,并且不会损害其优点。因此这些变动和更改在本发明的权利要求书范围内。
Claims (18)
1.一种组合物,包含蛋白质源、碳水化合物源、脂肪源、益生乳酸菌和额外的果糖-低聚糖和/或菊粉。
2.权利要求1的组合物,其包含一种或多种营养物或矿物质,选自维生素E、维生素C、维生素B6、叶酸、维生素B12、铜、锌和硒。
3.权利要求2的组合物,其中该组合物包含至少三种营养物或矿物质,选自维生素E、维生素C、维生素B6、叶酸、维生素B12、铜、锌和硒。
4.权利要求2或3的组合物,其中该组合物包含维生素E、维生素C、维生素B6、叶酸、维生素B12、铜、锌和硒。
5.以上权利要求之一的组合物,其包含一种或多种营养物或矿物质,选自钙、磷、镁、铁、维生素A、维生素B1、维生素B2、烟酸和维生素D。
6.权利要求5的组合物,其中该组合物包含至少三种营养物或矿物质,选自钙、磷、镁、铁、维生素A、维生素B1、维生素B2、烟酸和维生素D。
7.权利要求5或6的组合物,其中该组合物包含钙、磷、镁、铁、维生素A、维生素B1、维生素B2、烟酸和维生素D。
8.权利要求5-7之一的组合物,其中钙的形式是奶钙或衍生自奶钙的钙。
9.以上权利要求之一的组合物,其包含一种或多种益生乳酸菌,选自类干酪乳杆菌和约氏乳杆菌。
10.权利要求9的组合物,其中乳酸菌选自ST11(保藏号CNCMI-2116)和Lal(保藏号CNCMI-1225)。
11.以上权利要求之一的组合物,其中每300g该组合物包含下列质量或重量的营养物或矿物质(如果存在):
维生素E:约1IU-约400IU,
维生素C:约6mg-约300mg,
维生素B6:约0.17mg-约3mg,
叶酸:约40ug-约800ug,
维生素B12:约0.24mg-约5mg,
铜:约0.3mg-约3mg,
锌:约1.5mg-约15mg,
硒:约7ug-约300ug,
果糖-低聚糖和/或菊粉:约4g-约50g,
乳酸菌:约108-约1012cfu。
12.以上权利要求之一的组合物,其中每300g该组合物包含下列质量或重量的营养物或矿物质(如果存在):
钙:约100mg-约300mg,
磷:约50mg-约615mg,
镁:约110mg-约210mg,
维生素A:约1000IU-约1500IU,
维生素D:约50IU-约150IU,
维生素E:约5.0IU-约150IU,
维生素C:约30mg-约500mg,
维生素B1:约0.1mg-约2mg,
维生素B2:约0.1mg-约0.6mg,
烟酸:约1.5mg-约7.2mg,
维生素B6:约1.0mg-约3.0mg,
叶酸:约200ug-约600ug,
维生素B12:约1.5ug-约4.5ug,
铁:约2.0mg-约5mg,
锌:约10mg-约20mg。
13.以上权利要求之一的组合物,其包含阿拉伯树胶。
14.生产以上权利要求之一的组合物的方法,包括将所需营养物按照所需量混合在一起的步骤。
15.权利要求14的方法,包括将混合物挤出和/或将混合物喷雾干燥的附加步骤。
16.权利要求1-13之一的组合物在预防或治疗免疫疾病方面的用途。
17.权利要求1-13之一的组合物在生产用于预防或治疗免疫疾病的功能性食品或药剂的用途。
18.一种预防或治疗免疫疾病的方法,包括服用有效量的权利要求1-13之一的组合物。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0027761.6 | 2000-11-14 | ||
GBGB0027761.6A GB0027761D0 (en) | 2000-11-14 | 2000-11-14 | Nutritional composition for an immune condition |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA018188958A Division CN1503632A (zh) | 2000-11-14 | 2001-11-14 | 用于免疫疾病的营养组合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN103181564A true CN103181564A (zh) | 2013-07-03 |
Family
ID=9903140
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA018188958A Pending CN1503632A (zh) | 2000-11-14 | 2001-11-14 | 用于免疫疾病的营养组合物 |
CN2013100726216A Pending CN103181564A (zh) | 2000-11-14 | 2001-11-14 | 用于免疫疾病的营养组合物 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA018188958A Pending CN1503632A (zh) | 2000-11-14 | 2001-11-14 | 用于免疫疾病的营养组合物 |
Country Status (20)
Country | Link |
---|---|
US (2) | US6929793B2 (zh) |
EP (1) | EP1339294B2 (zh) |
JP (1) | JP2004513898A (zh) |
KR (1) | KR20030051802A (zh) |
CN (2) | CN1503632A (zh) |
AT (1) | ATE336909T1 (zh) |
AU (2) | AU2002221860B2 (zh) |
BR (1) | BR0115311A (zh) |
CA (1) | CA2427385C (zh) |
DE (1) | DE60122570T3 (zh) |
ES (1) | ES2269514T5 (zh) |
GB (1) | GB0027761D0 (zh) |
IL (1) | IL155674A (zh) |
MX (1) | MXPA03004268A (zh) |
NO (1) | NO326348B1 (zh) |
PL (1) | PL201161B1 (zh) |
RU (1) | RU2289955C2 (zh) |
UA (1) | UA78196C2 (zh) |
WO (1) | WO2002039834A1 (zh) |
ZA (1) | ZA200304605B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017133039A1 (zh) * | 2016-02-03 | 2017-08-10 | 程雪娇 | 一种牲畜饲料及制备方法 |
CN114848682A (zh) * | 2022-03-11 | 2022-08-05 | 中南大学湘雅三医院 | 维生素b6+益生菌合剂及其在制备减轻应激相关继发性损伤和无菌性炎症药物中的应用 |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7029702B2 (en) * | 1998-07-07 | 2006-04-18 | Ritter Natural Sciences Llc | Method for increasing lactose tolerance in mammals exhibiting lactose intolerance |
DE60322689D1 (de) * | 2002-04-09 | 2008-09-18 | Nestle Sa | La1- das genom von einem lactobacillus stamm |
JP2004059488A (ja) * | 2002-07-29 | 2004-02-26 | Asahi Food & Healthcare Ltd | 乳酸菌整腸組成物および食品 |
EP1530479A2 (de) * | 2002-08-16 | 2005-05-18 | Finzelberg GmbH & Co. KG | Arznei-, nahrungsergänzungsmittel und futtermittelzusatz |
GB2395627B (en) * | 2002-11-21 | 2006-05-10 | Hewlett Packard Co | Detector |
EP1643861B1 (en) | 2003-07-15 | 2011-05-11 | Nestec S.A. | High fibre high calorie liquid nutritional composition for gut health in the elderly patient |
GB0330009D0 (en) | 2003-12-24 | 2004-01-28 | Ferrosan As | Probiotic tablet formulations |
US20050245398A1 (en) * | 2004-04-29 | 2005-11-03 | Healthy Soils, Inc. | Biological composition for enhancing vegetation growth |
WO2006012536A2 (en) * | 2004-07-22 | 2006-02-02 | Ritter Andrew J | Methods and compositions for treating lactose intolerance |
US20100233312A9 (en) * | 2005-04-11 | 2010-09-16 | The Procter & Gamble Company | Compositions comprising probiotic and sweetener components |
EP3067057B1 (en) | 2005-09-28 | 2022-11-09 | Nordic Rebalance A/S | Probiotic fermented cereal compositions for use in treatment of gastrointestinal disorders caused by pro-inflammatory bacteria |
ZA200802935B (en) * | 2005-10-06 | 2009-11-25 | Brobi Ab | Use of lactobacillus for treatment of autoimmune diseases |
CA2635038A1 (en) † | 2005-12-29 | 2007-07-05 | Hill's Pet Nutrition, Inc. | Method for modifying gut flora in animals |
CA2641036A1 (en) * | 2006-02-13 | 2007-08-23 | Mcneil Nutritionals, Llc | Lactose-reduced dairy compositions and related methods |
KR101521123B1 (ko) | 2006-05-28 | 2015-05-19 | 시플라 메드프로 리서치 앤드 디벨롭먼트 (피티와이) 엘티디 | 프로바이오틱 스트레인 및 그로부터 유도된 항균 펩티드 |
US20080038432A1 (en) * | 2006-08-14 | 2008-02-14 | Hoffman Andrew J | Food Additive Comprising at Least One Fiber Source and at Least One Monosaccharide or Sugar Alcohol |
EP1992351B1 (en) | 2007-05-18 | 2016-05-11 | Nestec S.A. | Lactobacillus johnsonii for prevention of postsurgical infection |
WO2009004409A1 (en) * | 2007-06-29 | 2009-01-08 | Sirc - Natural & Dietetic Foods S.R.L. | Preparations contaning microorganisms |
US20100310713A1 (en) * | 2007-09-21 | 2010-12-09 | Kerry Group Services International Limited | Probiotic composition |
US20110223248A1 (en) * | 2007-12-12 | 2011-09-15 | Ritter Pharmaceuticals, Inc. | Methods and compositions for treating lactose intolerance |
CN102847153B (zh) * | 2008-01-10 | 2015-03-11 | 营养株式会社 | 用于改善高龄者的营养状态、降低发热次数和/或提高免疫能力的组合物 |
US20110189148A1 (en) * | 2008-06-25 | 2011-08-04 | Ritter Pharmaceuticals, Inc. | Lactose compositions with decreased lactose content |
US20100004334A1 (en) * | 2008-07-01 | 2010-01-07 | Mead Johnson Nutrition Company | Nutritional Compositions Containing Punicalagins |
EP2373185B1 (en) | 2009-01-02 | 2018-08-08 | Nestec S.A. | Food compositions having a realistic meat-like appearance, feel and texture |
US8785160B2 (en) | 2009-02-24 | 2014-07-22 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
CA2752800C (en) | 2009-02-24 | 2017-12-05 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
US20100233347A1 (en) * | 2009-03-13 | 2010-09-16 | Uhrhan Richard B | Food compositions having a realistic meat-like appearance, feel, and texture |
CN101828718B (zh) * | 2010-04-29 | 2012-12-26 | 北京世纪劲得保健品有限公司 | 一种高纤果蔬营养包及其制备方法 |
US20130178450A1 (en) | 2010-05-26 | 2013-07-11 | Nestec Sa | Methods for increasing the production or activity of catalase |
EP2397145A1 (en) * | 2010-06-18 | 2011-12-21 | Nestec S.A. | L. johnsonii La1, B. longum NCC2705 and immune disorders |
US20120015075A1 (en) * | 2010-07-13 | 2012-01-19 | Hero Nutritionals, LLC | Chewable supplement with live microorganisms |
JP6207157B2 (ja) * | 2010-09-24 | 2017-10-04 | 株式会社 バイオエルティ | Th3マーチ関連疾患の治療及び予防用医薬組成物 |
CN103442725A (zh) | 2011-01-25 | 2013-12-11 | 雀巢产品技术援助有限公司 | 治疗、减轻或预防动物的视觉系统衰退的方法和组合物 |
US20140037797A1 (en) * | 2011-02-07 | 2014-02-06 | Abbott Laboratories | Nutritional products comprising beta-hydroxy-beta-methylbutyrate |
MX359453B (es) | 2011-03-18 | 2018-09-28 | Nestec Sa | Composiciones y métodos útiles para aliviar los padecimientos relacionados con la edad. |
BR112013026447A2 (pt) | 2011-04-15 | 2016-10-18 | Nestec Sa | métodos para a regulação da expressão de gene de sirtuína |
TR201809987T4 (tr) | 2011-06-20 | 2018-08-27 | Heinz Co Brands H J Llc | Probiyotik bileşimler ve yöntemler. |
RU2485964C1 (ru) * | 2012-01-10 | 2013-06-27 | Сергей Александрович Староверов | Иммуностимулирующая композиция для животных |
US20140037813A1 (en) * | 2012-08-02 | 2014-02-06 | Mead Johnson Nutrition Company | Nutritional creamer composition |
US9820504B2 (en) | 2013-03-08 | 2017-11-21 | Axiom Foods, Inc. | Rice protein supplement and methods of use thereof |
CA2901469A1 (en) | 2013-03-08 | 2014-09-12 | Axiom Foods, Inc. | Rice protein supplements |
BR112015028164B1 (pt) | 2013-05-10 | 2022-02-08 | H.J. Heinz Company Brands Llc | Usos da bactéria probiótica, lactobacillus paracasei, para tratar uma infecção microbiana e para prevenir ou reduzir a gravidade de uma infecção microbiana |
CN103478716B (zh) * | 2013-09-23 | 2016-04-13 | 南昌大学 | 一种具有增强免疫力作用的功能食品的制备方法 |
JP6527522B2 (ja) | 2013-12-20 | 2019-06-05 | ネステク ソシエテ アノニム | 腸内病原菌を低減するための栄養組成物 |
CA2945895A1 (en) * | 2014-04-25 | 2015-10-29 | Nexira International | Use of a composition comprising arabic gum (ag) for improving gut impermeability |
PL3197297T3 (pl) * | 2014-09-23 | 2021-06-14 | Dom Terry International S.R.L. | Preparat prebiotyczny na bazie inuliny |
CN104432104A (zh) * | 2014-11-05 | 2015-03-25 | 江南大学 | 一种咸味高蛋白益生菌营养棒的制备方法 |
JP6905933B2 (ja) | 2014-11-25 | 2021-07-21 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 除脂肪体重を高め、体脂肪の増加を最小化し、かつ体重を管理するための方法及び組成物 |
JP7149075B2 (ja) | 2014-11-25 | 2022-10-06 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 減量中に除脂肪体重を維持し、かつ脂肪の低減を促進するための方法及び組成物 |
EP3342762A4 (en) | 2015-08-25 | 2019-04-03 | Nippon Shokubai Co., Ltd. | CEMENT ADDITIVE, CEMENT COMPOSITION AND RAW MATERIAL FOR CEMENT ADDITIVE |
US9855305B2 (en) | 2016-03-29 | 2018-01-02 | Companion Therapeutics Llc | Pharmaceutical composition containing combinations of vitamins, minerals, probiotics, and prebiotics effective in preventing adverse effects associated with the use of proton-pump inhibitors |
EP3634155A4 (en) | 2017-05-12 | 2021-02-17 | Axiom Foods Inc. | RICE PRODUCTS AND SYSTEMS AND PROCESSES FOR THEIR PRODUCTION |
US20220007685A1 (en) | 2018-10-18 | 2022-01-13 | Hill's Pet Nutrition, Inc. | Pet Food Compositions |
MX2021005534A (es) | 2018-12-13 | 2021-06-08 | Nestle Sa | Metodos para aumentar la oxidacion de grasa o el gasto de energia o la saciedad en un animal. |
EP3893661A1 (en) | 2018-12-13 | 2021-10-20 | Société des Produits Nestlé S.A. | Methods for enhancing metabolic health in an animal |
ES2940808T3 (es) | 2019-01-16 | 2023-05-11 | Nutricia Nv | Preparado fermentado con oligosacáridos no digeribles para su uso en infecciones inducidas por rotavirus |
MX2022006412A (es) | 2019-12-19 | 2022-08-02 | Nestle Sa | Composiciones y metodos para proporcionar un beneficio de salud a un animal en crecimiento. |
CN111329046A (zh) * | 2020-03-13 | 2020-06-26 | 上海复旦奥医医学科技有限公司 | 一种鼻咽癌专用型临床营养配方及其制备方法 |
WO2022049432A1 (en) | 2020-09-03 | 2022-03-10 | Societe Des Produits Nestle Sa | Compositions and methods for providing health benefits in an animal |
CA3188423A1 (en) | 2020-09-04 | 2022-03-10 | Francois-Pierre Martin | Compositions and methods for providing health benefits in an animal |
MX2023006498A (es) | 2020-12-11 | 2023-06-21 | Nestle Sa | Composiciones y metodos para alimento para mascotas. |
US20230165281A1 (en) | 2021-11-29 | 2023-06-01 | Société des Produits Nestlé S.A. | Methods and compositions for providing a health benefit in an animal |
US20230165277A1 (en) | 2021-11-29 | 2023-06-01 | Société des Produits Nestlé S.A. | Methods and compositions for providing a health benefit in an animal |
US20240085431A1 (en) | 2022-09-13 | 2024-03-14 | Société des Produits Nestlé S.A. | Methods for providing and determining an efficacious weight loss diet for a canine |
WO2024057117A1 (en) | 2022-09-14 | 2024-03-21 | Societe Des Produits Nestle Sa | Compositions and methods utilizing southern ocean mackerel oil for providing health benefits in an animal |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54129163A (en) | 1978-03-28 | 1979-10-06 | Fujiya Kk | Production of instant yogurt powder |
DE3727946A1 (de) * | 1987-08-21 | 1989-03-02 | Werner Georg Munk | Rekonstituierbares trockenprodukt zum direktverzehr, verfahren zu seiner herstellung und seine verwendung |
CH680192A5 (zh) * | 1989-12-13 | 1992-07-15 | Nestle Sa | |
JP3347381B2 (ja) * | 1993-01-27 | 2002-11-20 | 協和醗酵工業株式会社 | ペットフード |
US5565630A (en) | 1993-11-17 | 1996-10-15 | Monaghan Medical Corporation | Peak flow meter |
JP2973844B2 (ja) * | 1994-04-27 | 1999-11-08 | 不二製油株式会社 | クリームチーズ様食品の製造法 |
JPH08126473A (ja) * | 1994-09-08 | 1996-05-21 | Fuji Oil Co Ltd | 油性組成物およびその製法並びにそれを用いた油性被覆菓子 |
US6241983B1 (en) * | 1994-10-28 | 2001-06-05 | Metagenics, Inc. | Bacteria-and fiber-containing composition for human gastrointestinal health |
AUPN881396A0 (en) * | 1996-03-20 | 1996-04-18 | Arnott's Biscuits Limited | Enhancement of microbial colonization of the gastrointestinal tract |
DE69624805T3 (de) * | 1996-07-31 | 2007-01-04 | Raffinerie Tirlemontoise, S.A. | Fruktan- und/oder Polydextrose enthaltende Milchproduktpulver; Verfahren zu ihrer Herstellung und Verwendung derselben |
JP4065038B2 (ja) | 1996-08-07 | 2008-03-19 | カルピス株式会社 | 計算作業負荷ストレス緩和剤 |
TR200000021T2 (tr) * | 1997-07-05 | 2001-01-22 | Societe Des Produits Nestle S.A. | Bağırsak hücreleri tarafından minerallerin emilmesi. |
CN1208620A (zh) * | 1997-08-15 | 1999-02-24 | 陈秀枢 | 一种含双歧杆菌和乳杆菌的组合物 |
EP0904784A1 (en) * | 1997-09-22 | 1999-03-31 | N.V. Nutricia | Probiotic nutritional preparation |
US6093425A (en) * | 1997-11-21 | 2000-07-25 | Princeton Nutrition, L.L.C. | Complete nutritional milk compositions and products |
US6117477A (en) * | 1998-03-18 | 2000-09-12 | Kal Kan Foods, Inc. | Multicomponent food product and methods of making and using the same |
NZ510643A (en) * | 1998-08-21 | 2002-06-28 | Advanced Nutritional Foods Pty | Composition of calcium and an oligosaccharide |
DK1010374T3 (da) * | 1998-12-15 | 2005-11-21 | Nestle Sa | Fiberblanding til enterale sammensætninger |
CA2281463A1 (en) * | 1999-08-26 | 2001-02-26 | Stanley H. Zlotkin | Composition comprising micronutrients in combination with prebiotics, probiotics, and synbiotics |
GB2369777B (en) * | 2000-10-05 | 2004-10-27 | St Ivel Ltd | Food products with antimicrobial lactic acid bacteria |
GB0100273D0 (en) * | 2001-01-08 | 2001-02-14 | Nestle Sa | Nutritional composition for a bone condition |
-
2000
- 2000-11-14 GB GBGB0027761.6A patent/GB0027761D0/en not_active Ceased
-
2001
- 2001-11-14 RU RU2003117436/13A patent/RU2289955C2/ru not_active IP Right Cessation
- 2001-11-14 IL IL15567401A patent/IL155674A/xx not_active IP Right Cessation
- 2001-11-14 JP JP2002542219A patent/JP2004513898A/ja active Pending
- 2001-11-14 CA CA2427385A patent/CA2427385C/en not_active Expired - Lifetime
- 2001-11-14 CN CNA018188958A patent/CN1503632A/zh active Pending
- 2001-11-14 EP EP01996314.9A patent/EP1339294B2/en not_active Expired - Lifetime
- 2001-11-14 CN CN2013100726216A patent/CN103181564A/zh active Pending
- 2001-11-14 DE DE60122570.8T patent/DE60122570T3/de not_active Expired - Lifetime
- 2001-11-14 UA UA2003065544A patent/UA78196C2/uk unknown
- 2001-11-14 PL PL362438A patent/PL201161B1/pl not_active IP Right Cessation
- 2001-11-14 AT AT01996314T patent/ATE336909T1/de not_active IP Right Cessation
- 2001-11-14 BR BR0115311-0A patent/BR0115311A/pt not_active Application Discontinuation
- 2001-11-14 AU AU2002221860A patent/AU2002221860B2/en not_active Ceased
- 2001-11-14 KR KR10-2003-7006389A patent/KR20030051802A/ko not_active Application Discontinuation
- 2001-11-14 WO PCT/EP2001/013302 patent/WO2002039834A1/en active IP Right Grant
- 2001-11-14 ES ES01996314.9T patent/ES2269514T5/es not_active Expired - Lifetime
- 2001-11-14 MX MXPA03004268A patent/MXPA03004268A/es active IP Right Grant
- 2001-11-14 AU AU2186002A patent/AU2186002A/xx active Pending
-
2003
- 2003-05-12 NO NO20032129A patent/NO326348B1/no not_active IP Right Cessation
- 2003-05-13 US US10/436,477 patent/US6929793B2/en not_active Expired - Lifetime
- 2003-06-12 ZA ZA200304605A patent/ZA200304605B/en unknown
-
2005
- 2005-05-19 US US11/133,588 patent/US20050208035A1/en not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017133039A1 (zh) * | 2016-02-03 | 2017-08-10 | 程雪娇 | 一种牲畜饲料及制备方法 |
CN114848682A (zh) * | 2022-03-11 | 2022-08-05 | 中南大学湘雅三医院 | 维生素b6+益生菌合剂及其在制备减轻应激相关继发性损伤和无菌性炎症药物中的应用 |
Also Published As
Publication number | Publication date |
---|---|
EP1339294A1 (en) | 2003-09-03 |
JP2004513898A (ja) | 2004-05-13 |
US6929793B2 (en) | 2005-08-16 |
EP1339294B2 (en) | 2015-01-21 |
NO326348B1 (no) | 2008-11-17 |
IL155674A (en) | 2005-07-25 |
ZA200304605B (en) | 2004-09-13 |
US20050208035A1 (en) | 2005-09-22 |
DE60122570T3 (de) | 2015-05-21 |
RU2289955C2 (ru) | 2006-12-27 |
DE60122570D1 (de) | 2006-10-05 |
ES2269514T5 (es) | 2015-04-01 |
UA78196C2 (en) | 2007-03-15 |
ATE336909T1 (de) | 2006-09-15 |
ES2269514T3 (es) | 2007-04-01 |
US20040005305A1 (en) | 2004-01-08 |
DE60122570T2 (de) | 2007-09-20 |
PL362438A1 (en) | 2004-11-02 |
GB0027761D0 (en) | 2000-12-27 |
CA2427385C (en) | 2010-05-04 |
EP1339294B1 (en) | 2006-08-23 |
CN1503632A (zh) | 2004-06-09 |
PL201161B1 (pl) | 2009-03-31 |
WO2002039834A1 (en) | 2002-05-23 |
NO20032129D0 (no) | 2003-05-12 |
AU2002221860B2 (en) | 2006-08-10 |
IL155674A0 (en) | 2003-11-23 |
AU2186002A (en) | 2002-05-27 |
MXPA03004268A (es) | 2004-04-21 |
CA2427385A1 (en) | 2002-05-23 |
KR20030051802A (ko) | 2003-06-25 |
NO20032129L (no) | 2003-07-11 |
BR0115311A (pt) | 2004-01-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103181564A (zh) | 用于免疫疾病的营养组合物 | |
AU2002221860A1 (en) | Nutritional composition for an immune condition | |
DE60126104T2 (de) | Ernährungszusammensetzung und verfahren zur verbesserung der absetzung von proteinen | |
JP6285108B2 (ja) | 術前及び/又は術後環境におけるプロバイオティックス | |
EP0745333B1 (en) | Nutritional compositions in various forms | |
EP1401293B1 (en) | Calorically dense liquid oral supplement | |
CN108450938A (zh) | 一种减脂代餐粉及其制备方法 | |
EP1351584A2 (en) | Nutritional composition for a bone condition | |
EP2627196B1 (en) | Dairy based smoothie for stimulating growth in children | |
CN109588602A (zh) | 一种益生菌固体饮料 | |
EP1638418A1 (en) | Amino acid supplementation for a healthy microbiota ecosystem | |
JP2004041006A (ja) | 液状栄養組成物 | |
JPH1146720A (ja) | カルシウム吸収促進栄養組成物 | |
EP4059354A1 (en) | Synergistic combination of butyric-acid-producing prebiotics and probiotics | |
CN112753776A (zh) | 一种保护肠胃的奶粉及其制备方法 | |
Veniga | Osteoporosis: Implications for community health nursing | |
IES970234A2 (en) | Food Product |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C12 | Rejection of a patent application after its publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20130703 |