BR112013026447A2 - métodos para a regulação da expressão de gene de sirtuína - Google Patents
métodos para a regulação da expressão de gene de sirtuínaInfo
- Publication number
- BR112013026447A2 BR112013026447A2 BR112013026447A BR112013026447A BR112013026447A2 BR 112013026447 A2 BR112013026447 A2 BR 112013026447A2 BR 112013026447 A BR112013026447 A BR 112013026447A BR 112013026447 A BR112013026447 A BR 112013026447A BR 112013026447 A2 BR112013026447 A2 BR 112013026447A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- gene expression
- sirtuin gene
- regulating sirtuin
- regulating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Saccharide Compounds (AREA)
- Feed For Specific Animals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
resumo patente de invenção: "métodos para a regulação da expressão de gene de sirtuína". a presente invenção fornece os métodos úteis para a regulação da expressão de gene de sirtuína, simular a restrição calória, prevenir e tratar o mal de alzheimer, aumentar a longevidade e retardar o envelhecimento em um animal. os métodos compreendem a administração de uma ou mais isoflavonas aos animais, de preferência nas quantidades a partir de cerca de 0,001 a cerca de 10 g/ kg/ dia.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161517228P | 2011-04-15 | 2011-04-15 | |
PCT/US2012/030509 WO2012141876A1 (en) | 2011-04-15 | 2012-03-26 | Methods for regulating sirtuin gene expression |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013026447A2 true BR112013026447A2 (pt) | 2016-10-18 |
Family
ID=47009640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013026447A BR112013026447A2 (pt) | 2011-04-15 | 2012-03-26 | métodos para a regulação da expressão de gene de sirtuína |
Country Status (11)
Country | Link |
---|---|
US (1) | US20140039047A1 (pt) |
EP (2) | EP2898923A3 (pt) |
JP (1) | JP6140682B2 (pt) |
CN (1) | CN103596563A (pt) |
AU (1) | AU2012243210B2 (pt) |
BR (1) | BR112013026447A2 (pt) |
CA (1) | CA2832234A1 (pt) |
MX (1) | MX2013011996A (pt) |
RU (1) | RU2603749C2 (pt) |
WO (1) | WO2012141876A1 (pt) |
ZA (1) | ZA201308585B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102016078B1 (ko) | 2012-11-30 | 2019-08-30 | (주)아모레퍼시픽 | 심장 질환 예방 또는 치료용 조성물 |
US20170326100A1 (en) * | 2014-12-09 | 2017-11-16 | Amorepacific Corporation | Composition for activating longevity gene |
TWI556818B (zh) * | 2015-08-07 | 2016-11-11 | 長庚大學 | 哺乳類sirt1的活化劑 |
WO2021068242A1 (en) * | 2019-10-12 | 2021-04-15 | Shenzhen University | An agent that enables sirt7 gene expression and the use thereof |
CN111450098A (zh) * | 2020-04-20 | 2020-07-28 | 中国科学院动物研究所 | 拉米夫定在延缓衰老中的应用以及制备用于筛选延缓衰老药物的细胞模型 |
JPWO2021230145A1 (pt) * | 2020-05-11 | 2021-11-18 | ||
US20230310367A1 (en) * | 2020-09-04 | 2023-10-05 | Daicel Corporation | Composition for enhancing nampt gene expression |
CN115429810B (zh) * | 2021-06-03 | 2024-03-08 | 苏州禾研生物技术有限公司 | 异黄酮类化合物在制备预防或治疗酒精性肝损伤或解酒保肝的药物中的用途 |
WO2023150072A1 (en) | 2022-02-01 | 2023-08-10 | Sinclair David A | Compositions and methods for the preservation of plant matter |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5733926A (en) * | 1996-12-13 | 1998-03-31 | Gorbach; Sherwood L. | Isoflavonoids for treatment and prevention of alzheimer dementia and reduced cognitive functions |
US5952033A (en) | 1996-12-24 | 1999-09-14 | Nestec S.A. | Gelatinized cereal product containing oligosaccharide and processes of preparing and using same |
PT862863E (pt) | 1997-01-09 | 2002-04-29 | Nestle Sa | Produto cerealifero contendo probioticos |
US6359017B1 (en) * | 1999-02-24 | 2002-03-19 | Geza Bruckner | Dietary compositions and methods |
BR0013780A (pt) | 1999-09-07 | 2002-05-14 | Nestle Sa | Processo de melhoramento da pele e da pelagem de animais de estimação |
ES2261259T3 (es) | 1999-09-22 | 2006-11-16 | Societe Des Produits Nestle S.A. | Procedimiento para incrementar la actividad de los animales domesticos. |
EP1541673B1 (en) | 2000-05-25 | 2007-04-04 | Société des Produits Nestlé S.A. | Probiotics for pet food applications |
ES2269406T3 (es) | 2000-05-26 | 2007-04-01 | Societe Des Produits Nestle S.A. | Producto alimenticio para animales domesticos. |
GB0027761D0 (en) | 2000-11-14 | 2000-12-27 | Nestle Sa | Nutritional composition for an immune condition |
EP1344458A1 (en) | 2002-03-12 | 2003-09-17 | Société des Produits Nestlé S.A. | Probiotic delivery system |
CA2504682A1 (en) * | 2002-10-29 | 2004-05-13 | Colorado State University Research Foundation | Use of equol for treating androgen mediated diseases |
AU2005224017B2 (en) * | 2004-03-17 | 2010-12-16 | Société des Produits Nestlé S.A. | Compositions and methods for reducing or preventing obesity |
PT1755391E (pt) * | 2004-06-04 | 2016-02-03 | Univ Washington | Métodos e composições para o tratamento de neuropatias |
JP2008527002A (ja) * | 2005-01-13 | 2008-07-24 | サートリス ファーマシューティカルズ, インコーポレイテッド | 神経変性障害および血液凝固障害を予防および処置するための新規組成物 |
AU2006206274A1 (en) * | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Use of sirtuin-activating compounds for treating flushing and drug induced weight gain |
US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
EP1956923A1 (en) * | 2005-11-02 | 2008-08-20 | Nestec S.A. | Isoflavone compositions for reducing accumulation of body fat in male mammals, and methods for their use |
US8242100B2 (en) * | 2006-02-28 | 2012-08-14 | Nestec Sa | Compositions and methods for inducing bone growth and inhibiting bone loss |
US20080108696A1 (en) * | 2006-08-02 | 2008-05-08 | Brinton Roberta D | Phytoestrogenic Formulations for Alleviation or Prevention of Neurodegenerative Diseases |
CN101200459A (zh) * | 2006-12-11 | 2008-06-18 | 南京莱尔生物化工有限公司 | 一种雌马酚的合成方法 |
-
2012
- 2012-03-26 JP JP2014505156A patent/JP6140682B2/ja not_active Expired - Fee Related
- 2012-03-26 CN CN201280029380.0A patent/CN103596563A/zh active Pending
- 2012-03-26 CA CA2832234A patent/CA2832234A1/en not_active Abandoned
- 2012-03-26 AU AU2012243210A patent/AU2012243210B2/en not_active Ceased
- 2012-03-26 BR BR112013026447A patent/BR112013026447A2/pt not_active IP Right Cessation
- 2012-03-26 US US14/111,617 patent/US20140039047A1/en not_active Abandoned
- 2012-03-26 MX MX2013011996A patent/MX2013011996A/es unknown
- 2012-03-26 EP EP15158963.7A patent/EP2898923A3/en not_active Withdrawn
- 2012-03-26 RU RU2013150828/10A patent/RU2603749C2/ru not_active IP Right Cessation
- 2012-03-26 EP EP12770611.7A patent/EP2696692A4/en not_active Withdrawn
- 2012-03-26 WO PCT/US2012/030509 patent/WO2012141876A1/en active Application Filing
-
2013
- 2013-11-14 ZA ZA2013/08585A patent/ZA201308585B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2012243210B2 (en) | 2016-07-14 |
RU2013150828A (ru) | 2015-05-20 |
WO2012141876A1 (en) | 2012-10-18 |
EP2898923A2 (en) | 2015-07-29 |
EP2898923A3 (en) | 2015-10-07 |
MX2013011996A (es) | 2013-11-01 |
CA2832234A1 (en) | 2012-10-18 |
JP6140682B2 (ja) | 2017-05-31 |
EP2696692A1 (en) | 2014-02-19 |
AU2012243210A1 (en) | 2013-10-24 |
JP2014516359A (ja) | 2014-07-10 |
US20140039047A1 (en) | 2014-02-06 |
RU2603749C2 (ru) | 2016-11-27 |
ZA201308585B (en) | 2015-06-24 |
CN103596563A (zh) | 2014-02-19 |
EP2696692A4 (en) | 2014-10-01 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2507 DE 22-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |