CN103053604A

CN103053604A - Synergistic insecticidal composition containing flonicamid and silafluofen and application thereof

Info

Publication number: CN103053604A
Application number: CN2011103197520A
Authority: CN
Inventors: 齐武; 刘奎涛; 夏向荣; 赵立嵚; 顾起财
Original assignee: Nanjing Huazhou Pharmaceutical Co Ltd
Current assignee: Nanjing Huazhou Pharmaceutical Co Ltd
Priority date: 2011-10-20
Filing date: 2011-10-20
Publication date: 2013-04-24

Abstract

The invention discloses a synergistic insecticidal composition containing flonicamid and silafluofen and application thereof. The synergistic insecticidal composition comprises main effective components of flonicamid and silafluofen in a weight ratio of 0.1-80:0.1-55. The composition provided by the invention can be used for the control of Hemiptera insects and produce high synergism, overcomes and delays the insect resistance, expands spectrum of control, and has fast insecticidal speed, reduced drug usage cost, and especially has control effect on aphid and whitefly significantly higher than that of a single agent.

Description

Synergistic insecticidal compositions of a kind of fluorine-containing pyridine insect amide and silafluofene and uses thereof

Technical field

The invention belongs to pesticide field, relate to a kind of Pesticidal combination and uses thereof, especially a kind of Pesticidal combination take flonicamid and silafluofene as active component and uses thereof.

Background technology

Flonicamid (flonicamid, flunicotamid), chemical name: N-cyanogen methyl. (trifluoromethyl) vitamin PP.

Flonicamid belongs to the lower toxicity insecticide variety.This agent is effective to various suckings pest, and has good osmosis.It can be from root to stem, the infiltration of leaf section, but by leaf section to stem, root osmosis relatively a little less than.

This medicament causes effect by hindering the insect act of sucking.Insect stops to suck after taking in medicament very soon, and is last hungry and dead.

Insect according to electronics sucks behavior (EMIII) parsing, and this agent can make the lancet tissue of the sucking insects such as aphid can't insert plant tissue and cause effect.10% water dispersible granules, every 667m when the insects such as vegetable aphid such as control cucumber ²Use 10% water dispersible granules 30-50g that water is sprayed.When for fruit aphids such as control apples, add water 2500-5000 with 10% water dispersible granules and doubly spray.Use proof through test and land for growing field crops, flonicamid is to various aphids, plant hopper, aleyrodid, leafhopper, fruit bat, wireworm, thrips, ant class, leaf miner, and the first-class sucking pest of springtail has special efficacy, and pests with chewing mouthparts is also had good control efficiency.

Silafluofene (alphacypermethrin) chemical name: (4-ethoxybenzene) [4-fluoro-(3-phenoxy group benzene) propyl group] dimethylsilane, it is a kind of siliceous novel Organophosphorus insecticides thing, tool stomach toxicity and action of contace poison have the characteristics such as activity is high, low to mammal and toxicity in fish, stable chemical nature.Termite is shown good repellent action.Rat acute per os LD ₅₀Greater than 5000 mg/kgs.

At present, the Semiptera insect, such as termite, aphid etc., resistance increases gradually, and the agricultural chemicals single dose descends gradually to the effect of control of insect, there is no effective preparation for the control of Semiptera insect.The inventor finds that after deliberation the synergistic complex of agricultural chemicals is expanding prevention spectrum and the effective measures that improve preventive effect, not yet finds up to now the Pesticidal combination of relevant flonicamid and silafluofene.

Summary of the invention

The Synergistic insecticidal compositions that the purpose of this invention is to provide a kind of fluorine-containing pyridine insect amide and silafluofene, but this Pesticidal combination high-efficiency prevention and control resistance Semiptera insect, production cost is low, have quick-acting and the long-acting pesticidal effect.

The present invention also provides this Insecticidal combinations to prevent and treat application in the resistance Semiptera insect insecticidal materials in preparation.

For achieving the above object, the present invention takes full advantage of both mutual supplement with each other's advantages by the network analysis to flonicamid and silafluofene insecticidal properties, and flonicamid and silafluofene is composite according to certain ratio.

The objective of the invention is to implement in the following manner:

The Synergistic insecticidal compositions of a kind of fluorine-containing pyridine insect amide and silafluofene is characterized in that this Synergistic insecticidal compositions take flonicamid and pyridalyl as main active ingredient, and wherein, the weight ratio of flonicamid and silafluofene is 0.1～80: 0.1～55.The weight ratio of preferred flonicamid and silafluofene is 0.2～50: 0.5～50, and the weight ratio of further preferred flonicamid and silafluofene is 0.5～30: 1～40.

In the present composition, the two weight percentage that accounts for composition of flonicamid and silafluofene is 1～80%.Preferably the two weight percentage that accounts for composition is 3～50%." % " of the present invention is mass percent.

Pesticidal combination of the present invention take flonicamid and silafluofene as main active ingredient (active component) and insecticides adjuvant, excipient be mixed with any one formulation that allows on the agricultural chemicals.The preferred missible oil of described formulation, aqueous emulsion, microemulsion and suspending agent.Described auxiliary agent can adopt calcium dodecyl benzene sulfonate, emulsifier 600 #, polyoxyethylene polyoxy third rare block compound (such as farming breast 33 ^#), the one or more combinations in the polyoxyethylene nonylphenol ether, excipient comprises cyclohexanone, solvent naphtha, solvent naphtha, water, antifreezing agent (such as propane diols), deionized water etc.Above auxiliary agent, excipient can alone or also also can add other auxiliary material mixing use with reaching.

Above-mentioned Pesticidal combination is prevented and treated application in the insecticidal materials of resistance Semiptera insect in preparation, especially anti-eliminate aphis and aleyrodid on successful be higher than its single dose and use

Beneficial effect of the present invention:

The invention provides the Pesticidal combination of a kind of flonicamid and silafluofene, it compared with prior art can produce higher synergistic function, and overcome and delayed pest resistance to insecticide, the expanding prevention spectrum, desinsection speed is fast, has reduced drug cost.Compare with single dose, said composition antagonism Semiptera insect has notable synergistic such as aphid and aleyrodid etc., has obviously improved control efficiency.

Embodiment

Embodiments of the invention are the methods that adopt indoor bioassay and field trial to combine.First by indoor bioassay, the co-toxicity coefficient after clear and definite two kinds of medicaments are composite by a certain percentage; On this basis, carry out again field trial.

Embodiment 1:

Taking by weighing flonicamid, silafluofene, to adopt the conventional formulation method to be mixed with active ingredient alkene quality percentage composition by different proportion be 25% missible oil, and concrete ratio sees Table 1,2:

Employing is soaked the worm leaf dipping method and is carried out indoor synergy biologicall test, and selecting the resistance cotten aphid is target pest, and every processing repeats 3 times, uses LC ₅₀Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:

The Toxicity Determination of the composite and single dose antagonism cotten aphid of table 1. flonicamid-silafluofene:

Data show in the table, and flonicamid and silafluofene are mixed and rear cotten aphid are had synergistic effect, and three listed in table proportioning co-toxicity coefficients are all much larger than 120, so flonicamid and silafluofene are mixed and have significant synergies.

Employing is soaked the leaf dip method and is carried out indoor synergy biologicall test, and selecting the resistance aleyrodid is target pest, and every processing repeats 3 times, uses LC ₅₀Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:

The Toxicity Determination of the composite and single dose antagonism aleyrodid of table 2. flonicamid-silafluofene:

Data show in the table, and flonicamid and silafluofene are mixed and rear aleyrodid are had synergistic effect, and three listed in table proportioning co-toxicity coefficients are all much larger than 120, so flonicamid and silafluofene are mixed and have significant synergies.

Adopt embodiment 2 and 3, according to every mu of ground difference medication 10g, 20g, 25g medicament, the contrast medicament is 10% silafluofene WP 30g/ mu, 5% flonicamid AS30g/ mu, every mu of ground water 30kg prevention and control of aphides.4 days, 10 days, 15 days, 20 days, 30 days fruits that come to an end after the dispenser, and process, the results are shown in Table 3:

Table 3: the composite field test results to cotten aphid of flonicamid-silafluofene

As can be known from the above table, the flonicamid silafluofene is composite to be better than 10% silafluofene wetting powder, 5% flonicamid aqua to the cotten aphid drug effect, demonstrates the superiority of prescription.

Adopt embodiment 2 and 3, according to every mu of ground difference medication 10g, 20g, 25g medicament, the contrast medicament is 10% alpha-cypermethrin WP 30g/ mu, 5% flonicamid AS30g/ mu, every mu of ground water 30kg control aleyrodid.4 days, 10 days, 15 days, 20 days, 30 days fruits that come to an end after the dispenser, and process, the results are shown in Table 4:

Table 4: the composite field test results to aleyrodid of flonicamid-silafluofene

As can be known from the above table, the flonicamid silafluofene is composite to be better than 10% silafluofene wetting powder, 5% flonicamid aqua to the aleyrodid drug effect, demonstrates the superiority of prescription.

Embodiment 2:

Take by weighing the 5g flonicamid, the 5g silafluofene is dissolved in the 8g solvent naphtha, adds 1g ethylene glycol and 5g emulsifier 600 # again, stir.Mentioned solution is slowly poured in the excess water, under fully stirring, made preparation 10% flonicamid silafluofene aqueous emulsion.

Embodiment 3:

Take by weighing the 1.5g flonicamid, the 8.5g silafluofene is dissolved in the 8g solvent naphtha, adds 1g ethylene glycol and 5g emulsifier 600 # again, stir.Mentioned solution is slowly poured in the excess water, under fully stirring, made preparation 10% flonicamid silafluofene aqueous emulsion.

Embodiment 4:

Take by weighing the 1g flonicamid, the 5g silafluofene is dissolved in the 8g solvent naphtha, adds 1g ethylene glycol and 5g emulsifier 600 # again, stir.Mentioned solution is slowly poured in the excess water, under fully stirring, made preparation 6% flonicamid silafluofene aqueous emulsion.

Embodiment 5:

Take by weighing 2g flonicamid, 20g silafluofene, emulsifier 1602#4g, emulsifier 500#2g, 1-METHYLPYRROLIDONE 4g, isopropyl alcohol 6g, solvent naphtha 3g, surplus is water, the method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and makes 22% flonicamid silafluofene microemulsion.

Embodiment 6:

Take by weighing 5g flonicamid, 45g silafluofene, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 28g makes 50% flonicamid pyridine worm the third water dispersible granules with above raw material by the method for water dispersion granule.

Embodiment 7:

Take by weighing 60g flonicamid, 5g silafluofene, 1g lauryl sodium sulfate, 0.5g dispersing agent NNO, kaolin to 100g, above raw material is prepared routinely the method for wetting powder and mixed, form 65% flonicamid silafluofene wetting powder.

Embodiment 8:

Take by weighing 10g flonicamid, 15g silafluofene, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is water, above raw material is prepared the method for suspending agent routinely, make 25% flonicamid silafluofene suspending agent.

Embodiment 9:

Take by weighing 5g flonicamid, 30g silafluofene, emulsifier 600 #14g, phenethyl phenol polyethenoxy ether 15g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and makes 35% flonicamid silafluofene missible oil.

Embodiment 10:

Take by weighing 0.1g flonicamid, 50g silafluofene, calcium dodecyl benzene sulfonate 3g, emulsifier 600 #4g, phenethyl phenol polyethenoxy ether 3g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and makes 50.1% flonicamid silafluofene missible oil.

Embodiment 11:

Take by weighing 50g flonicamid, 30g silafluofene, calcium dodecyl benzene sulfonate 3g, emulsifier 600 #4g, phenethyl phenol polyethenoxy ether 5g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and makes 80% flonicamid silafluofene missible oil.

Embodiment 12:

Take by weighing 20g flonicamid, 20g silafluofene, 600#5g, phenethyl phenol polyethenoxy ether 6g, 1-METHYLPYRROLIDONE 4g, isopropyl alcohol 6g, solvent naphtha 3g, surplus is water, the method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and makes 40% flonicamid pyridalyl microemulsion.

Embodiment 13:

Take by weighing 70g flonicamid, 0.5g silafluofene pyridalyl, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 7.5g makes 70.5% flonicamid silafluofene pyridalyl water dispersible granules with above raw material by the method for water dispersion granule.

Claims

1. the Synergistic insecticidal compositions of a fluorine-containing pyridine insect amide and silafluofene is characterized in that this Synergistic insecticidal compositions take flonicamid and silafluofene as main active ingredient, and wherein, the weight ratio of flonicamid and silafluofene is 0.1～80: 0.1～55.

2. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide according to claim 1 and silafluofene is characterized in that in this Synergistic insecticidal compositions, and the weight ratio of flonicamid and silafluofene is 0.2～50: 0.5～50.

3. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide according to claim 2 and silafluofene is characterized in that the weight ratio of flonicamid and silafluofene is 0.5～30: 1～40 in this Synergistic insecticidal compositions.

4. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide according to claim 1 and silafluofene is characterized in that the two weight percentage that accounts for composition of flonicamid and silafluofene is 1～80%.

5. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide according to claim 4 and silafluofene is characterized in that the two weight percentage that accounts for composition of flonicamid and silafluofene is 3～50%.

6. according to claim 1, the Synergistic insecticidal compositions of 2 or 3 described fluorine-containing pyridine insect amides and silafluofene, it is characterized in that it take flonicamid and silafluofene as main active ingredient and insecticides adjuvant and excipients are mixed with any one formulation that allows on the agricultural chemicals.

7. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide according to claim 6 and silafluofene is characterized in that described formulation is missible oil, aqueous emulsion, microemulsion or suspending agent.

8. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide claimed in claim 1 and silafluofene is prevented and treated application in the insecticidal materials of resistance Semiptera insect in preparation.

9. the Synergistic insecticidal compositions of fluorine-containing pyridine insect amide claimed in claim 1 and silafluofene is prevented and treated application in resistance Semiptera insect aphid and the aleyrodid insecticidal materials in preparation.