CN103053586A - Synergistic insecticidal composition containing dinotefuran and thiamethoxam, and application thereof - Google Patents
Synergistic insecticidal composition containing dinotefuran and thiamethoxam, and application thereof Download PDFInfo
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- CN103053586A CN103053586A CN2011103208845A CN201110320884A CN103053586A CN 103053586 A CN103053586 A CN 103053586A CN 2011103208845 A CN2011103208845 A CN 2011103208845A CN 201110320884 A CN201110320884 A CN 201110320884A CN 103053586 A CN103053586 A CN 103053586A
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Abstract
The invention discloses a synergistic insecticidal composition containing dinotefuran and thiamethoxam, and an application thereof. The synergistic insecticidal composition employs dinotefuran and thiamethoxam as main effective components, wherein a weight ratio of dinotefuran to thiamethoxam is 0.1-70 : 0.2-70. The insecticidal composition can produce a relatively high synergistic interaction effect, overcomes or delays pest resistance, has fast insecticidal speed and long efficacy duration and reduces pesticide cost. The insecticidal composition can be used for preventing hemiptera pests and lepidoptera pests, is particularly suitable for preventing plant hopper, aleyrodid, leafhopper and aphid, and has an effect obviously higher than that of a single dosage.
Description
Technical field
The invention belongs to pesticide field, be specifically related to a kind of Synergistic insecticidal compositions and application thereof take MTI-446 and Diacloden as main active ingredient.
Background technology
MTI-446 (dinotefuran) is the third generation nicotinic insecticide of Mitsui chemical company exploitation.The chemical constitution of itself and existing nicotinic insecticide is far from each other, and chloro-pyridine base, chloro thiazolyl before its tetrahydrofuran base has replaced do not contain the halogen family element.Simultaneously, also different with nicotine at aspect of performance.So people are referred to as " furans nicotine " at present.MTI-446 chemical name: 1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine.
A new generation's anabasine insecticide MTI-446 Main Function makes the insect paralysis dead in insect neurotransmission system.This medicament insecticidal spectrum is wide, has remarkable interior sorptivety and thoroughly acts on, and namely shown very high insecticidal activity at very low dosage.This medicament is fool proof to mammal, birds and aquatile, and crop without poisoning, be can be used for numerous crops such as paddy rice, fruit tree, vegetables.To rice grub brown planthopper, white-backed planthopper, small brown rice planthopper, rice leafhopper, rice spider rafter stinkbug, star stinkbug, green rice bug resemble, red must fleahopper, the negative mixed worm of rice, rice cylinder water snout moth's larva be efficient.Effective to striped rice borer, oryza chinensis class.Efficient to vegetables, fruit insect Phytophthira, aleyrodid class, a red-spotted lizard class, unaspis shield kuwana, the green stinkbug of Zhu, peach fruit borer, tangerine lyonetid, the thin moth of tea, striped flea-beetle, the beans fly of diving.The cured a red-spotted lizard in diagonal angle, diamond-back moth, two secret notes are chrysomelid, tea golden thistle horse, onion thrips, golden thistle horse, oranges and tangerines golden thistle horse, soybean pod gall-midge, tomato Liriomyza are effective.MTI-446 has very wide insecticidal spectrum, and fool proof again to crop, people and animals and environment, is equipped with the using method of various uses again, this agricultural chemicals large-tonnage agricultural chemicals that is expected to become international.
Diacloden (Thiamethoxam), the nicotinic insecticide of new generation of Novartis Co.,Ltd's (existing is by Syngenta Co.,Ltd) in 1991 exploitation, chemical name: 3-(2-chloro-5-thiazolyl methyl)-5-methyl-N-nitro-4H-1,3,5-Si Qing oxadiazine-4-imines, structural formula is as follows:
Diacloden belongs to the lower toxicity insecticide variety.Its mechanism of action is similar to Imidacloprid, alternative inhibition insect central nervous system nicotinic acid nAChR ligands, and then the normal conduction of blocking-up insect central nervous system, thereby the normal nervous activity of interference insect, insect is in the state of being on wires, and is dead in paralysis gradually.This medical instrument have tag, stomach toxicity and systemic activity, can reach preferably insecticidal activity by plant roots, stem and leaf Assimilation and conductivity.Diacloden is owing to the difference of process preparation, and controlling object and operation technique show slightly different.25% water dispersible granules is applicable to cotton, wheat, paddy rice, apple, pears, citrus, tobacco, vegetables and economic crops and is watered spraying.And 70% dried kind of clothing agent, the seed treatment of applicable various crops.Use proof through test and land for growing field crops, Diacloden is to various aphids, plant hopper, aleyrodid, leafhopper, fruit bat, wireworm, thrips, ant class, leaf miner, and the first-class sucking pest of springtail has special efficacy, and pests with chewing mouthparts is also had good control efficiency.Diacloden except as the foliar spray, also is used for seed and soil treatment on producing, but with the seed treatment best results.
Rice fulgorid and aphid are under the condition of present long-term prescription, resistance increases gradually, the agricultural chemicals single dose descends gradually to the effect of control of insect, study discovery through the inventor, the synergistic complex of agricultural chemicals is expanding prevention spectrum and the effective measures that improve preventive effect, not yet finds up to now the Synergistic insecticidal compositions of relevant MTI-446 and Diacloden.
Summary of the invention
The purpose of this invention is to provide a kind of Synergistic insecticidal compositions that contains MTI-446 and Diacloden.
Another object of the present invention provides said composition and prevents and treats application on the insecticidal materials of resistance Semiptera, coleopteran pest in preparation.
For achieving the above object, MTI-446 and Thiamethoxam compound that the present invention will grow the lasting period obtain new and effective multifunctional insecticide composition.This insecticidal materials has good preventive effect to Semiptera and the coleopteran pest that plant hopper, aleyrodid, leafhopper and aphid etc. produce resistance easily; And suppress insect to the pesticide resistance generation of unitary agent (MTI-446 or Diacloden are arbitrary).
The objective of the invention is to be achieved through the following technical solutions:
A kind of Synergistic insecticidal compositions that contains MTI-446 and Diacloden is characterized in that it take MTI-446 and Diacloden as main active ingredient, and wherein, the weight ratio of MTI-446 and Diacloden is 0.1～70: 0.2～70.The weight ratio of MTI-446 and Diacloden preferred 1～50 in this Synergistic insecticidal compositions: 1～50, more preferably 1～20: 1～20, most preferably 1～8: 1～8.
In the present composition, the two percentage by weight that accounts for composition of MTI-446 and Diacloden is 1～80%.Be preferably 5～50%, most preferably 5～40%.The effective ingredient of above-mentioned Insecticidal combinations is present in the composition with the synergy effective dose." % " of the present invention is mass percent.
Above-mentioned Insecticidal combinations is take MTI-446 and Diacloden as main active ingredient (active component), and insecticides adjuvant, excipients are mixed with any one formulation that allows on the agricultural chemicals.Be preferably missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion and water dispersion granule.
Described auxiliary agent can adopt the one or more combinations in calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, polyoxyethylene polyoxy third rare block compound (such as the newborn 33# of farming), the polyoxyethylene nonylphenol ether, and excipient comprises isopropyl alcohol, solvent naphtha, water, dimethyl formamide, antifreezing agent (such as propane diols), deionized water etc.Above auxiliary agent, excipient and other auxiliary material can alone or and usefulness.
Above-mentioned Pesticidal combination can be prevented and treated application in the insecticidal materials of resistance Semiptera, coleopteran pest in preparation, and the control efficiency of the present composition is used apparently higher than its single dose, and described Semiptera insect refers in particular to plant hopper, aleyrodid, leafhopper and aphid.
Show through indoor synergism test mensuration: built agent all has significant synergistic insecticidal action; Field control effectiveness test shows that equally also all built agents of the present invention all are significantly higher than the effect of corresponding single dose agricultural chemicals to the insecticidal effect of water rice hopper and wheat aphid.
Pesticidal combination of the present invention compared with prior art, produce following beneficial effect: (1) is compared with single dose, and said composition has notable synergistic to insect, has obviously improved control efficiency; (2) one medicines are controlled more, and a dispenser can prevent and treat various pests simultaneously, reduce control recruitment cost; (3) alternative high-toxic pesticide, and significantly reduce the field dosage, effective environmental contamination reduction and residue of pesticide; (4) have concurrently quick-acting and long-acting; (5) compare with the MTI-446 single dose, produce and the use cost reduction; (6) suppress insect to the resistance enhancing of agricultural chemicals.
Embodiment
Embodiments of the invention are the methods that adopt indoor bioassay and field trial to combine.First by indoor bioassay, the co-toxicity coefficient after clear and definite two kinds of medicaments are composite by a certain percentage; On this basis, carry out again field trial.
Embodiment 1:
Taking by weighing MTI-446, Diacloden, to adopt the conventional formulation method to be mixed with main effectively composition quality percentage composition by different proportion be 30% MTI-446 Diacloden missible oil, and concrete ratio sees Table 1,2.
Adopt rice stem infusion process to carry out indoor synergy biologicall test, selecting the resistant rice plant hopper is target pest, and every processing repeats 3 times, and every concentration is processed 60, uses LC
50Value is calculated co-toxicity coefficient by the Y-factor method Y of majoring in of the abundant method introduction of Sun Yun, determines whether mixture has synergistic function:
The toxicity test of table 1 MTI-446 and Thiamethoxam compound and single dose antagonism rice fulgorid.
As shown in Table 1, MTI-446 and Thiamethoxam compound, co-toxicity coefficient show good synergistic function all greater than 120.
Selecting the resistance wheat aphid is that the worm leaf dipping method is soaked in the target pest employing, and every processing repeats 3 times, uses LC
50Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:
The toxicity test of table 2 MTI-446 and Thiamethoxam compound and single dose antagonism wheat aphid.
As shown in Table 2, MTI-446 and Thiamethoxam compound all greater than 120, show good synergistic function to the co-toxicity coefficient of wheat aphid.
Adopt embodiment 2 and 3 sample product of embodiment to carry out the field trial of control in field Brown Planthopper, the contrast medicament is 10% Diacloden WDG and 10% MTI-446 WP, and concrete consumption sees Table 3, and every mu of water consumption is 30kg, looked into behind the medicine 4 days, 10 days, 15 days, 20 days, 30 days results, result of the test sees Table 3:
Table 3: MTI-446 Thiamethoxam compound and single dose are to the field control effectiveness test of brown planthopper
As can be known from the above table, 10.5% MTI-446 Diacloden missible oil and 11% MTI-446 Diacloden microemulsion are better than 25% Diacloden WDG, 10% MTI-446 WP to the water rice hopper drug effect, demonstrate the superiority of prescription.
Adopt embodiment 2 and 3 sample product of embodiment to carry out the field trial of control in field wheat aphid, the contrast medicament is 10% Diacloden WDG and 10% MTI-446 WP, and concrete consumption sees Table 3, and every mu of water consumption is 30kg, looked into behind the medicine 4 days, 10 days, 15 days, 20 days, 30 days results, result of the test sees Table 4:
Table 4: MTI-446 Thiamethoxam compound and single dose are to the field control effectiveness test of wheat aphid
As can be known from the above table, 10.5% MTI-446 Diacloden missible oil and 11% MTI-446 Diacloden microemulsion are better than 25% Diacloden WDG, 10% MTI-446 WP to the wheat aphid drug effect, demonstrate the superiority of prescription.
Embodiment 2:
Take by weighing 8g MTI-446,2g Diacloden, calcium dodecyl benzene sulfonate 4g, phenethyl phenol polyethenoxy ether 3g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and making main active ingredient weight percentage is 10% MTI-446 Diacloden missible oil.
Embodiment 3:
Take by weighing 2g MTI-446,8g Diacloden, emulsifier 1602
#4g, emulsifier 500
#2g, 1-METHYLPYRROLIDONE 4g, isopropyl alcohol 6g, solvent naphtha 3g, surplus is water, and the method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and making main active ingredient weight percentage is 10% MTI-446 Diacloden microemulsion.
Embodiment 4:
Take by weighing 60g MTI-446,5g Diacloden, 1g lauryl sodium sulfate, 0.5g dispersing agent NNO, kaolin to 100g, above raw material is prepared routinely the method for wetting powder and mixed, making main active ingredient weight percentage is 65% MTI-446 Diacloden wetting powder.
Embodiment 5:
Take by weighing 80g MTI-446,0.2g Diacloden, calcium dodecyl benzene sulfonate 5g, phenethyl phenol polyethenoxy ether 5g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and making main active ingredient weight percentage is 80.2% MTI-446 Diacloden missible oil.
Embodiment 6:
Take by weighing 20g MTI-446,2g Diacloden, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is water, above raw material is prepared the method for suspending agent routinely, and making main active ingredient weight percentage is 22% MTI-446 Diacloden suspending agent.
Embodiment 7:
Take by weighing 30g MTI-446,0.5g Diacloden, calcium dodecyl benzene sulfonate 12g, phenethyl phenol polyethenoxy ether 8g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and making main active ingredient weight percentage is 30.5% MTI-446 Diacloden missible oil.
Embodiment 8:
Take by weighing 2g MTI-446,20g Diacloden, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin complement to 100g above raw material are made 22% MTI-446 Diacloden water dispersion granule by the method for water dispersion granule.
Embodiment 9:
Take by weighing 5g MTI-446,30g Diacloden, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is water, above raw material is prepared the method for suspending agent routinely, make 35% MTI-446 Diacloden suspending agent.
Embodiment 10:
Take by weighing 0.1g MTI-446,70g Diacloden, alkylphenol polyoxyethylene 10g, phenethyl phenol polyethenoxy ether 10g, solvent naphtha to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and making main active ingredient weight percentage is 70.1% MTI-446 Diacloden missible oil.
Embodiment 11:
Take by weighing the 20g MTI-446, the 0.2g Diacloden is dissolved in the 8g solvent naphtha, adds 1g ethylene glycol and 5g alkylphenol polyoxyethylene disodium sulfosuccinate again, stir.Mentioned solution is slowly poured in the excess water, and under fully stirring, making main active ingredient weight percentage is 20.2% MTI-446 Diacloden aqueous emulsion.
Claims (10)
1. Synergistic insecticidal compositions that contains MTI-446 and Diacloden is characterized in that it take MTI-446 and Diacloden as main active ingredient, and wherein, the weight ratio of MTI-446 and Diacloden is 0.1～70: 0.2～70.
2. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden according to claim 1 is characterized in that the effective ingredient MTI-446 of this Pesticidal combination and the weight ratio of Diacloden are 1～50: 1～50.
3. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden according to claim 2 is characterized in that the effective ingredient MTI-446 of this Pesticidal combination and the weight ratio of Diacloden are 1～20: 1～20.
4. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden according to claim 1 is characterized in that the two weight percentage that accounts for composition of MTI-446 and Diacloden is 1～80%.
5. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden according to claim 4 is characterized in that the two weight percentage that accounts for composition of MTI-446 and Diacloden is 5～50%.
6. the compound pesticide compositions that contains MTI-446 and Diacloden according to claim 5 is characterized in that the two weight percentage that accounts for composition of MTI-446 and Diacloden is 5～40%.
7. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden according to claim 1 is characterized in that it take MTI-446 and Diacloden as main active ingredient and insecticides adjuvant, excipients are mixed with any one formulation that allows on the agricultural chemicals.
8. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden according to claim 7 is characterized in that described formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion or water dispersion granule.
9. the Synergistic insecticidal compositions that contains MTI-446 and Diacloden claimed in claim 1 is prevented and treated the application on the insecticidal materials of resistance Semiptera, coleopteran pest in preparation.
10. the application of Synergistic insecticidal compositions on the insecticidal materials of preparation control plant hopper, aleyrodid, leafhopper and aphid that contains MTI-446 and Diacloden claimed in claim 1.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104886114A (en) * | 2015-06-12 | 2015-09-09 | 福建省德盛生物工程有限责任公司 | Low-volume spray containing thiamethoxam and dinotefuran |
| CN105104408A (en) * | 2015-09-25 | 2015-12-02 | 安徽美兰农业发展股份有限公司 | Dinotefuran and thiamethoxam compounded wettable powder and preparation method thereof |
| CN107980813A (en) * | 2017-11-27 | 2018-05-04 | 来安县义坤农业发展有限公司 | A kind of insecticide for preventing Lin crambid |
| CN113475535A (en) * | 2018-03-02 | 2021-10-08 | 中国农业科学院棉花研究所 | Method for extracting castor-containing insecticidal active substance and combined application of castor-containing insecticidal active substance and neonicotinoid insecticide |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101304659A (en) * | 2005-11-10 | 2008-11-12 | 拜尔农作物科学股份公司 | Synergistic insecticidal mixtures for seed treatment |
| CN102007931A (en) * | 2010-11-29 | 2011-04-13 | 陕西韦尔奇作物保护有限公司 | Dinotefuran-containing pesticidal composition |
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2011
- 2011-10-20 CN CN2011103208845A patent/CN103053586A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101304659A (en) * | 2005-11-10 | 2008-11-12 | 拜尔农作物科学股份公司 | Synergistic insecticidal mixtures for seed treatment |
| CN102007931A (en) * | 2010-11-29 | 2011-04-13 | 陕西韦尔奇作物保护有限公司 | Dinotefuran-containing pesticidal composition |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104886114A (en) * | 2015-06-12 | 2015-09-09 | 福建省德盛生物工程有限责任公司 | Low-volume spray containing thiamethoxam and dinotefuran |
| CN105104408A (en) * | 2015-09-25 | 2015-12-02 | 安徽美兰农业发展股份有限公司 | Dinotefuran and thiamethoxam compounded wettable powder and preparation method thereof |
| CN105104408B (en) * | 2015-09-25 | 2017-03-22 | 安徽美兰农业发展股份有限公司 | Dinotefuran and thiamethoxam compounded wettable powder and preparation method thereof |
| CN107980813A (en) * | 2017-11-27 | 2018-05-04 | 来安县义坤农业发展有限公司 | A kind of insecticide for preventing Lin crambid |
| CN113475535A (en) * | 2018-03-02 | 2021-10-08 | 中国农业科学院棉花研究所 | Method for extracting castor-containing insecticidal active substance and combined application of castor-containing insecticidal active substance and neonicotinoid insecticide |
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Application publication date: 20130424 |