CN103053523B

CN103053523B - Synergistic insecticidal composition containing flonicamid and pyridalyl and application thereof

Info

Publication number: CN103053523B
Application number: CN201110319744.6A
Authority: CN
Inventors: 杨寿海; 郭崇友; 陈文明; 杨志国; 贠琰
Original assignee: Nanjing Huazhou Pharmaceutical Co Ltd
Current assignee: Nanjing Redsun Co., Ltd.; Nanjing Huazhou Pharmaceutical Co Ltd
Priority date: 2011-10-20
Filing date: 2011-10-20
Publication date: 2014-07-23
Anticipated expiration: 2031-10-20
Also published as: CN103053523A

Abstract

The invention discloses a synergistic insecticidal composition containing flonicamid and pyridalyl and application thereof. The synergistic insecticidal composition comprises main effective components of flonicamid and pyridalyl in a weight ratio of 0.1-80:0.2-70. The insecticidal composition can produce high synergetic effect, overcomes and delays the insect resistance, and has high insecticidal speed, long duration and reduced use cost. The composition provided by the invention can control hemipteran pests in crops, especially rice planthopper, whiteflies and aphids, and has effect obviously higher than that of a single agent.

Description

A kind of Synergistic insecticidal compositions and application thereof containing flonicamid and pyridalyl

Technical field

The invention belongs to pesticide field, be specifically related to a kind of Synergistic insecticidal compositions and application thereof that flonicamid and pyridalyl be main active ingredient of take.

Background technology

Flonicamid (flonicamid, flunicotamid), chemical name: N-cyanogen methyl. (trifluoromethyl) vitamin PP.Flonicamid belongs to lower toxicity insecticide variety.This agent is effective to various suckings pest, and has good osmosis.It can be from root to stem, the infiltration of leaf portion, but by leaf portion to stem, root osmosis relatively a little less than.This medicament causes effect by hindering insect act of sucking.Insect stops sucking after taking in medicament very soon, last hungry and dead.

Insect according to electronics sucks behavior (EMIII) parsing, and this agent can make the lancet tissue of the sucking insects such as aphid cannot insert plant tissue and cause effect.10% water dispersible granules, every 667m when the insects such as vegetable aphid such as control cucumber ²use 10% water dispersible granules 30-50g to spray water.When preventing and treating the fruit aphids such as apple, with 10% water dispersible granules, add water 2500-5000 and doubly spray.Through test and land for growing field crops, use proof, flonicamid is to various aphids, plant hopper, aleyrodid, leafhopper, fruit bat, wireworm, thrips, ant class, leaf miner, and the first-class sucking pest of springtail has special efficacy, and pests with chewing mouthparts is also had to good control efficiency.But at present, the homoptera pests such as plant hopper and aphid are under the condition of long-term prescription, resistance increases gradually, uses separately flonicamid can not effectively prevent and treat this class pest.

Pyridalyl (pyridalyl), chemical name 2, the chloro-4-of 6-bis-(3,3-, bis-chloroallyloxyaminos) phenyl 3-[5-(trifluoromethyl-2 hydroxy pyrimidine) propyl group] ether.Structural formula is as follows:

Pyridalyl has simultaneously tags and stomach poison function, and the larva of lepidoptera pest main in agricultural production is had to very high insecticidal activity.In addition, pyridalyl also demonstrates good insecticidal activity to thrips and dipterous insect, contrary with its high activity, and pyridalyl is very low to various useful arthropodan toxicity.

Summary of the invention

The object of this invention is to provide a kind of Synergistic insecticidal compositions containing flonicamid and pyridalyl.

Another object of the present invention is to provide above-mentioned Synergistic insecticidal compositions and prevents and treats the application in resistance Semiptera insect insecticidal materials in preparation.

For achieving the above object, the present invention is composite by different two kinds of insecticidal materials flonicamids and the pyridalyl of controlling object, obtains the new and effective multifunctional insecticide composition of a class.The various pests that this Pesticidal combination easily produces resistance to rice fulgorid, aphid, diamond-back moth has good preventive effect; And suppress insect the pesticide resistance of unitary agent (flonicamid or pyridalyl) is produced.

The present invention adopts following technical scheme:

Containing a Synergistic insecticidal compositions for flonicamid and pyridalyl, it is characterized in that it is main active ingredient that this Synergistic insecticidal compositions be take flonicamid and pyridalyl, wherein, the weight ratio of flonicamid and pyridalyl is 0.1～80: 0.2～70.

In this Synergistic insecticidal compositions, the weight ratio of flonicamid and pyridalyl preferably 0.5～60: 2～50, and more preferably 1～30: 4～20.

In the present composition, the two percentage by weight that accounts for composition of flonicamid and pyridalyl is 3～80%.Be preferably 5～50%, most preferably 5～20%." % " of the present invention is mass percent.

It is main active ingredient (active component) that above-mentioned Insecticidal combinations be take flonicamid and pyridalyl, and insecticides adjuvant, excipients are mixed with any one formulation allowing on agricultural chemicals.Be preferably missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion and water dispersion granule.

Described auxiliary agent specifically can adopt usual auxiliaries, if calcium dodecyl benzene sulfonate, emulsifier 600 #, the rare block compound of polyoxyethylene polyoxy third are (as agriculture breast 33 ^#), polyoxyethylene nonylphenol ether etc., excipient can adopt cyclohexanone, solvent naphtha, solvent naphtha, water, antifreezing agent (as propane diols), deionized water etc.Auxiliary agent, excipient can alone or mixing use, also can add other auxiliary material allowing on pesticidal preparations.

Above-mentioned Pesticidal combination can be prevented and treated the application in the insecticidal materials of resistance Semiptera insect in preparation, and the control efficiency of the present composition is used apparently higher than its single dose, and described Semiptera insect refers in particular to rice fulgorid, aphid, aleyrodid.

Indoor bioassay and field control effectiveness test show that compound insecticidal medicine of the present invention has significant synergistic insecticidal action to Semiptera insect, is all significantly higher than the effect of corresponding single dose agricultural chemicals especially to the insecticidal effect of water rice hopper, aphid, aleyrodid.

Beneficial effect of the present invention: the flonicamid providing of the present invention and pyridalyl Pesticidal combination, can produce higher synergistic function, desinsection speed is fast, overcome and delayed pest resistance to insecticide, expanding prevention spectrum, has reduced drug cost simultaneously, and its successful is used higher than its single dose.

Embodiment

Embodiments of the invention are the methods that adopt indoor bioassay and field trial to combine.First by indoor bioassay, the co-toxicity coefficient after clear and definite two kinds of medicaments are composite by a certain percentage; On this basis, then carry out field trial.

Embodiment 1:

Take flonicamid, pyridalyl employing conventional formulation method, be mixed with the flonicamid pyridalyl missible oil that active ingredient quality percentage composition is 30% respectively by different proportion, concrete ratio is in Table 1,2.

Adopt rice stem infusion process to carry out indoor synergy biologicall test, selecting resistant rice plant hopper is target pest, and every processing repeats 3 times, and every concentration is processed 60, uses LC ₅₀value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:

The Toxicity Determination of table 1. flonicamid and pyridalyl composition and single dose antagonism rice fulgorid thereof:

In table, data show, after flonicamid and pyridalyl are mixed, Brown Planthopper are had to synergistic effect, and three proportioning co-toxicity coefficients listed in table are all much larger than 120, so flonicamid and pyridalyl are mixed and have significant synergies.

Employing is soaked leaf dip method and is carried out indoor synergy biologicall test, and selecting resistance aleyrodid is target pest, and every processing repeats 3 times, uses LC ₅₀value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:

The Toxicity Determination of table 2. flonicamid and pyridalyl Synergistic insecticidal compositions and single dose antagonism aleyrodid thereof:

In table, data show, after flonicamid and pyridalyl are mixed, aleyrodid are had to synergistic effect, and three proportioning co-toxicity coefficients listed in table are all much larger than 120, and flonicamid and pyridalyl are mixed and have significant synergies.

Adopt the sample of embodiment 2 and 3, according to every mu of ground medication 10g, 20g, 25g preparation, contrast medicament is 10% pyridalyl WP30g/ mu, 5% flonicamid AS30g/ mu, every mu of ground water 30kg control Brown Planthopper.Within after dispenser 4 days, 10 days, 15 days, 20 days, 30 days, come to an end really, and carry out data processing, the results are shown in Table 3:

Table 3: flonicamid and the field test results of pyridalyl Synergistic insecticidal compositions to Brown Planthopper

As can be known from the above table, flonicamid pyridalyl is composite is better than 10% pyridalyl wetting powder, 5% flonicamid aqua to water rice hopper drug effect, demonstrates the superiority of formula.

Adopt the sample of embodiment 2 and 3, according to every mu of ground medication 10g, 20g, 25g medicament, contrast medicament is 10% pyridalyl WP30g/ mu, 5% flonicamid AS30g/ mu, every mu of ground water 30kg, the aleyrodid on control cucumber.Within after dispenser 4 days, 10 days, 15 days, 20 days, 30 days, come to an end really, and process, the results are shown in Table 4:

Table 4: the composite field test results to aleyrodid of flonicamid-pyridalyl

As can be known from the above table, flonicamid pyridalyl is composite is better than 10% pyridalyl wetting powder, 5% flonicamid aqua to aleyrodid drug effect, demonstrates the superiority of formula.

Embodiment 2:

Take 10g flonicamid, 0.5g pyridalyl is dissolved in 8g solvent naphtha, then adds 1g ethylene glycol and 5g emulsifier 600 #, stir.Above-mentioned solution is slowly poured in excess water to gross weight 100g, under fully stirring, made 10.5% flonicamid pyridalyl aqueous emulsion.

Embodiment 3:

Take 10g flonicamid, 1g pyridalyl is dissolved in 8g solvent naphtha, then adds 1g ethylene glycol and 5g600# disodium sulfosuccinate, stir.Above-mentioned solution is slowly poured in excess water, under fully stirring, made 11% flonicamid pyridalyl aqueous emulsion.

Embodiment 4:

Take 45g flonicamid, 5g pyridalyl is dissolved in 8g solvent naphtha, then adds 1g ethylene glycol and 5g600# disodium sulfosuccinate, stir.Above-mentioned solution is slowly poured in excess water, under fully stirring, made 50% flonicamid pyridalyl aqueous emulsion.

Embodiment 5:

Take 2g flonicamid, 20g pyridalyl, emulsifier 600 #5g, phenethyl phenol polyethenoxy ether 6g, 1-METHYLPYRROLIDONE 4g, isopropyl alcohol 6g, solvent naphtha 3g, surplus is water, the method that above raw material is prepared to microemulsion routinely drops in mixing kettle mixes, and makes 22% flonicamid pyridalyl microemulsion.

Embodiment 6:

Take 5g flonicamid, 45g pyridalyl, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 28g, makes 50% flonicamid pyridalyl water dispersion granule by above raw material by the method for water dispersion granule.

Embodiment 7:

Take 75g flonicamid, 0.2g pyridalyl, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is water, above raw material is prepared routinely to the method for suspending agent, made 75.2% flonicamid pyridalyl suspending agent.

Embodiment 8:

Take 10g flonicamid, 15g pyridalyl, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is water, above raw material is prepared routinely to the method for suspending agent, made 25% flonicamid pyridalyl suspending agent.

Embodiment 9:

Take 5g flonicamid, 70g pyridalyl, calcium dodecyl benzene sulfonate 4g, emulsifier 600 #4g, phenethyl phenol polyethenoxy ether 5g, solvent naphtha to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and makes 75% flonicamid pyridalyl missible oil.

Embodiment 10:

Take 0.1g flonicamid, 30g pyridalyl, calcium dodecyl benzene sulfonate 4g, emulsifier 600 #4g, phenethyl phenol polyethenoxy ether 6g, solvent naphtha to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and makes 30.1% flonicamid pyridalyl missible oil.

Embodiment 11:

Take 30g flonicamid, 20g pyridalyl, calcium dodecyl benzene sulfonate 4g, emulsifier 600 #5g, phenethyl phenol polyethenoxy ether 6g, solvent naphtha to 100g, the method that above raw material is prepared to missible oil routinely drops in mixing kettle mixes, and makes 50% flonicamid pyridalyl missible oil.

Embodiment 12:

Take 60g flonicamid, 5g pyridalyl, 1g lauryl sodium sulfate, 0.5g dispersing agent NNO, kaolin to 100g, above raw material is prepared routinely to the method for wetting powder and mixed, form 65% flonicamid pyridalyl wetting powder.

Claims

1. containing a Synergistic insecticidal compositions for flonicamid and pyridalyl, it is characterized in that it is active ingredient that this Synergistic insecticidal compositions be take flonicamid and pyridalyl, wherein, the weight ratio of flonicamid and pyridalyl is 10:1,15:1 or 20:1.

2. the Synergistic insecticidal compositions containing flonicamid and pyridalyl according to claim 1, is characterized in that the two weight percentage that accounts for composition of flonicamid and pyridalyl is 3 ~ 80%.

3. the Synergistic insecticidal compositions containing flonicamid and pyridalyl according to claim 2, is characterized in that the two weight percentage that accounts for composition of flonicamid and pyridalyl is 5 ~ 50%.

4. according to the Synergistic insecticidal compositions containing flonicamid and pyridalyl described in claim 1,2 or 3, it is characterized in that it take flonicamid and pyridalyl and be mixed with any one formulation allowing on agricultural chemicals as active ingredient and insecticides adjuvant.

5. the Synergistic insecticidal compositions containing flonicamid and pyridalyl according to claim 4, is characterized in that described formulation is missible oil, suspending agent, aqueous emulsion, wetting powder, microemulsion or water dispersion granule.

6. the Synergistic insecticidal compositions containing flonicamid and pyridalyl claimed in claim 1 is prevented and treated the application in the insecticidal materials of resistance Semiptera insect in preparation.

7. the application of the Synergistic insecticidal compositions containing flonicamid and pyridalyl claimed in claim 1 in the insecticidal materials of preparation control water rice hopper, aleyrodid, aphid.