CN102017987A - synergistic insecticidal composition containing nitenpyram and cypermethrin and application thereof - Google Patents

Abstract

The invention relates to a synergistic insecticidal composition containing nitenpyram and cypermethrin and application thereof. In the composition, nitenpyram and cypermethrin are utilized as main effective components, wherein the mass ratio of the nitenpyram to the cypermethrin is 0.1-80:0.1-70. The insecticidal composition can generate higher synergism, overcome and delay the drug resistance of pests, achieve the effects of high insecticidal speed and long effect-lasting duration and reduce the pesticide cost and has better control effect in comparison with the use of a single agent. The composition can be used for preparing pesticides for controlling resistant hemiptera pests.

Description

A kind of Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin and uses thereof

Technical field

The present invention relates to a kind of Pesticidal combination and uses thereof, especially a kind of is Pesticidal combination of main active and uses thereof with Nitenpyram and cypermethrin.

Background technology

Nitenpyram (nitenpyram), chemical name are (E)-N-(6-chloro-3 pyridylmethyls)-N-ethyl-N '-methyl-2-nitro ethenylidene diamines.Structural formula is as follows:

This medicine insecticidal spectrum is wide, be widely used on agricultural and the gardening prevent eliminating aphis, leafhopper, thrips, Semiptera insect, toxicity is low, lasting medicine does not have poisoning, safe in utilization to crop; This medicine acts on nAChR, and the mode uniqueness has remarkable interior suction and osmosis, and market prospects are comparatively wide, but its commercially available price is higher.

Cypermethrin (cypermethrin) is a kind of pyrethoid insecticides thing, has and tags and stomach poison function.Insecticidal spectrum is wide, drug effect is rapid, to light, thermally-stabilised, the ovum of some insect is had lethal effect.Respond well to the phosphorus wing order larva, the Semiptera insect also there is favorable effect, be applicable to crops such as cotton, fruit tree, tea tree, soybean, beet.But it is longer that this insecticide is used the time, and many insects are single with having produced pesticide resistance and drug resistance in various degree to it.

At present, the Semiptera insect, increase gradually as resistances such as cotten aphid, vegetable aphid, aleyrodids, the agent of agricultural chemicals list descends gradually to the effect of control of insect, the inventor finds after deliberation, agriculture chemical compounding can obviously improve drug effect, and delays the generation of pest resistance, and still finds no the Pesticidal combination that closes Nitenpyram and cypermethrin up to now.

Summary of the invention

The purpose of this invention is to provide a kind of Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin, but this Pesticidal combination high-efficiency prevention and control resistance Semiptera insect, and production cost low, have quick-acting and the long-acting pesticidal effect.

The present invention also provides this desinsection to be combined in the application for preparing on the insecticidal materials of preventing and treating resistance Semiptera insect.

A kind of Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin, it is main active ingredient with Nitenpyram and cypermethrin, wherein, the mass ratio of Nitenpyram and cypermethrin is 0.1～80: 0.1～70, preferred 0.2～60: 0.5～50.The optimum quality ratio of Nitenpyram and cypermethrin is 0.5～40: 5～45 in this Pesticidal combination.

The two quality percentage composition that accounts for composition of Nitenpyram and cypermethrin is 1～70%, and is preferred 6～50%, and optimum is 8～45%.Effective ingredient is present in the composition with the synergy effective dose in this Pesticidal combination.

Pesticidal combination of the present invention is that main active ingredient and the known auxiliary agent of agricultural chemicals, excipient are mixed with any one formulation that allows on the agricultural chemicals with Nitenpyram and cypermethrin, preferred missible oil, aqueous emulsion, microemulsion and suspending agent.Described auxiliary agent can adopt wooden sodium sulfonate, phenethyl phenol polyethenoxy ether, alkylphenol polyoxyethylene disodium sulfosuccinate, calcium dodecyl benzene sulfonate, alkylphenol polyoxyethylene, polyoxyethylene polyoxy third rare block compound, dispersing agent NNO, kaolin, polyoxyethylene nonylphenol ether, N-Methyl pyrrolidone, borax etc., and excipient comprises cyclohexanone, dimethylbenzene, solvent naphtha, ethylene glycol, water, antifreezing agent (as propane diols), isopropyl alcohol etc.Above auxiliary agent, excipient can singly be used or and use or and other known auxiliary material mixing use commonly used.

The Semiptera insect that Pesticidal combination antagonism cotten aphid of the present invention, vegetable aphid and aleyrodid etc. are easy to generate resistance has good preventive effect; And the inhibition insect is to the pesticide resistance generation of unitary agent (Nitenpyram or cypermethrin).Therefore, Pesticidal combination of the present invention can be used on preparation prevents and treats the insecticidal materials of resistance Semiptera insect, particularly anti-ly eliminates aphis in preparation, uses on the insecticidal materials of aleyrodid and plant hopper." % " of the present invention is mass percent.

Beneficial effect of the present invention: Pesticidal combination of the present invention, can produce higher cooperative synergism, overcome and delayed pest resistance to insecticide, desinsection speed is fast, and the lasting period is long, has reduced drug cost, and control efficiency is used apparently higher than its single agent.

Embodiment

Embodiments of the invention are the methods that adopt indoor bioassay and field trial to combine.Pass through indoor bioassay, the co-toxicity coefficient after clear and definite two kinds of medicaments are composite by a certain percentage earlier; On this basis, carry out field trial again.

Embodiment 1:

Taking by weighing Nitenpyram, cypermethrin, to adopt the conventional formulation method to be mixed with main effectively composition quality percentage composition by different proportion be 30% Nitenpyram permethrin milk oil.Concrete ratio sees Table 1,2.

Employing is soaked the leaf dip method and is carried out indoor synergy biologicall test, and selecting the resistance cotten aphid is target pest, and every processing repeats 3 times, uses LC ₅₀Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:

The Toxicity Determination of table 1. Nitenpyram-cypermethrin compounded and single agent antagonism cotten aphid:

Data show in the table 1, and Nitenpyram and the cypermethrin back that is mixed has synergistic effect to cotten aphid, and three listed in table proportioning co-toxicity coefficients are all much larger than 120, so Nitenpyram and cypermethrin are mixed and have significant synergies.

Employing is soaked the leaf dip method and is carried out indoor synergy biologicall test, and selecting the resistance aleyrodid is target pest, and every processing repeats 3 times, uses LC ₅₀Value is pressed the abundant method of Sun Yun and is calculated co-toxicity coefficient:

Table 2. Nitenpyram-cypermethrin compounded and single agent is to the Toxicity Determination of aleyrodid:

Data show in the table 2, and Nitenpyram and the cypermethrin back that is mixed has synergistic effect to aleyrodid, and three listed in table proportioning co-toxicity coefficients are all much larger than 120, so Nitenpyram and cypermethrin are mixed and have significant synergies.

Adopt embodiment 2 and the field trial that sample carries out the control in field cotten aphid that embodiment 3 joins, the contrast medicament is 10% cypermethrin WP and 5% Nitenpyram AS, and concrete consumption sees Table 3, and every mu of water consumption is 30kg, looked into behind the medicine 4 days, 10 days, 15 days, 20 days, 30 days results, result of the test sees Table 3:

Table 3: Nitenpyram-cypermethrin compounded field test results to cotten aphid

As can be known from the above table, Nitenpyram is cypermethrin compounded to be better than 10% cypermethrin wetting powder, 5% Nitenpyram aqua to the cotten aphid drug effect, demonstrates the superiority of prescription.

Adopt embodiment 2 and the field trial that sample carries out the control in field aleyrodid that embodiment 3 joins, the contrast medicament is 10% cypermethrin WP and 5% Nitenpyram AS, and concrete consumption sees Table 4, and every mu of water consumption is 30kg, looked into behind the medicine 4 days, 10 days, 15 days, 20 days, 30 days results, result of the test sees Table 4:

Table 4: Nitenpyram-cypermethrin compounded field test results to aleyrodid

As can be known from the above table, Nitenpyram is cypermethrin compounded to be better than 10% cypermethrin wetting powder, 5% Nitenpyram aqua to the aleyrodid drug effect, demonstrates the superiority of prescription.

Embodiment 2:

Take by weighing the 0.5g Nitenpyram, the 10g cypermethrin is dissolved in the 8g dimethylbenzene, adds 1g ethylene glycol and 5g alkylphenol polyoxyethylene disodium sulfosuccinate again, stir.Above-mentioned solution is slowly poured in the excess water, fully stirred down, form preparation 10.5% Nitenpyram aqueous emulsion of cypermethrin.

Embodiment 3:

Take by weighing the 2g Nitenpyram, the 30g cypermethrin is dissolved in the 8g dimethylbenzene, adds 1g ethylene glycol and 5g alkylphenol polyoxyethylene disodium sulfosuccinate again, stir.Above-mentioned solution is slowly poured in the excess water, fully stirred down, form preparation 32% Nitenpyram aqueous emulsion of cypermethrin.

Embodiment 4:

Take by weighing 45g Nitenpyram, 5g cypermethrin, 1g lauryl sodium sulfate, 0.5g dispersing agent NNO, add kaolin, above raw material is prepared routinely the method for wetting powder and mixed, form 65% Nitenpyram cypermethrin wetting powder to 100g.

Embodiment 5:

Take by weighing 2g Nitenpyram, 20g cypermethrin, emulsifier 1602 ^#4g, emulsifier 500 ^#2g, N-Methyl pyrrolidone 4g, isopropyl alcohol 6g, dimethylbenzene 3g, surplus is a water, the method that above raw material is prepared microemulsion routinely drops in the mixing kettle mixes, and forms 22% Nitenpyram cypermethrin microemulsion.

Embodiment 6:

Take by weighing 5g Nitenpyram, 45g cypermethrin, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 28g forms 50% Nitenpyram pyridine worm, third water dispersible granules with above raw material by the method for water dispersion granule.

Embodiment 7:

Take by weighing 36g Nitenpyram, 16g cypermethrin, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is a water, above raw material is prepared the method for suspending agent routinely, form 52% Nitenpyram cypermethrin suspending agent.

Embodiment 8:

Take by weighing 10g Nitenpyram, 15g cypermethrin, methyl naphthalene sulfonate formaldehyde condensate 6g, polyoxyethylene nonylphenol ether 3g, aluminium-magnesium silicate 0.5g, ethylene glycol 7g, tributyl phosphate 2g, silicone oil 0.2g, surplus is a water, above raw material is prepared the method for suspending agent routinely, form 25% Nitenpyram cypermethrin suspending agent.

Embodiment 9:

Take by weighing 60g Nitenpyram, 0.5g cypermethrin, calcium dodecyl benzene sulfonate 3g, alkylphenol polyoxyethylene 4g, phenethyl phenol polyethenoxy ether 5g, dimethylbenzene to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms 60.5% Nitenpyram permethrin milk oil.

Embodiment 10:

Take by weighing 0.1g Nitenpyram, 30g cypermethrin, alkylphenol polyoxyethylene 14g, phenethyl phenol polyethenoxy ether 15g, dimethylbenzene to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms 30.1% Nitenpyram permethrin milk oil.

Embodiment 11:

Take by weighing 5g Nitenpyram, 55g cypermethrin, alkylphenol polyoxyethylene 14g, phenethyl phenol polyethenoxy ether 15g, dimethylbenzene to 100g, the method that above raw material is prepared missible oil routinely drops in the mixing kettle mixes, and forms 60% Nitenpyram permethrin milk oil.

Embodiment 12:

Take by weighing 65g Nitenpyram, 5g cypermethrin, the 8g of wooden sodium sulfonate, lauryl sodium sulfate 2g, ammonium sulfate 5g, polyvinyl alcohol 5g, borax 2g, kaolin 8g forms 70% Nitenpyram pyridine worm, third water dispersible granules with above raw material by the method for water dispersion granule.

Claims (9)

1. a Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin is characterized in that it is main active ingredient with Nitenpyram and cypermethrin, and wherein, the mass ratio of Nitenpyram and cypermethrin is 0.1～80: 0.1～70.

2. the Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin according to claim 1, the mass ratio that it is characterized in that described Nitenpyram and cypermethrin is 0.2～60: 0.5～50.

3. the Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin according to claim 1, the mass ratio that it is characterized in that described Nitenpyram and cypermethrin is 0.5～40: 5～45.

4. the Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin according to claim 1 is characterized in that the two quality percentage composition that accounts for composition of described Nitenpyram and cypermethrin is 1～70%.

5. the Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin according to claim 1 is characterized in that the two quality percentage composition that accounts for composition of described Nitenpyram and cypermethrin is 6～50%

6. the Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin according to claim 1 is characterized in that it is that main active ingredient and insecticides adjuvant and excipients are mixed with any one formulation that allows on the agricultural chemicals with Nitenpyram and cypermethrin.

7. the Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin according to claim 1 is characterized in that described formulation is missible oil, aqueous emulsion, microemulsion or suspending agent.

8. the described Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin of claim 1 is prevented and treated the application on the insecticidal materials of resistance Semiptera insect in preparation.

The described Synergistic insecticidal compositions that contains Nitenpyram and cypermethrin of claim 8 anti-ly eliminate aphis in preparation, the application on the insecticidal materials of aleyrodid and plant hopper.