CN102805102B - Disinsection combination containing fosthiazate and ryanodine receptor inhibitor insecticide - Google Patents
Disinsection combination containing fosthiazate and ryanodine receptor inhibitor insecticide Download PDFInfo
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- CN102805102B CN102805102B CN201210318054.3A CN201210318054A CN102805102B CN 102805102 B CN102805102 B CN 102805102B CN 201210318054 A CN201210318054 A CN 201210318054A CN 102805102 B CN102805102 B CN 102805102B
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Abstract
The invention discloses disinsection combination containing fosthiazate and ryanodine receptor inhibitor insecticide. The first active ingredient of the combination is fosthiazate, the second active ingredient is selected from ryanodine receptor inhibitor insecticide, such as chlorantraniliprole, cyantraniliprole or flubendiamide, and the weight ratio of the first active ingredient to the second active ingredient is 1:20 to 20:1. The combination can be prepared into agriculturally allowable missible oil, atrazine or granula formulations, has the advantages that the components are reasonable, the insecticidal efficacy is good, the activity and the insecticidal efficacy of the combination are not the simple supraposition of the activity of all the components, and compared with the existing single formulation, the combination not only has obvious insecticidal efficacy, but also has obvious potentiation, has high safety, and meets the safety requirement of pesticide formulation.
Description
Technical field
The present invention relates to a kind of Pesticidal combination, particularly a kind of fosthiazate is as the first active component, be selected from the Rynaxypyr of ryanodine receptor inhibitor insecticides, bromine cyanogen insect amide or fipronil bisamide as the Pesticidal combination of the second active component, belong to technical field of compounded pesticide.
Background technology
Fosthiazate, English common name fosthiazate, chemical name: O-ethyl-S-sec-butyl-2-oxo-1,3-thiazoles alkane-3-base Thiophosphonate is organic phosphor nematocide.The mode of action suppresses the acetylcholinesterase of insect, has good interior absorption, is mainly used in preventing and treating nematode, aphid etc.
Ryanodine receptor inhibitor insecticides is a class novel insecticidal agent of in recent years developing, the brand-new mechanism of action, and defines new insecticide series of products.The principal item that this insecticides is successfully developed at present has Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide etc.
Rynaxypyr; trade name health is wide; English common name: Chlorantraniliprole; the bromo-N-of chemical name: 3-[4-chloro-2-methyl-6-[(methyl-carbamoyl) benzene]-1-(3-chloropyridine-2-base)-1-hydrogen-pyridine-5-formamide; for the anthranilamide-based ryanodine receptor agent of E.I.Du Pont Company's exploitation; excellent to lepidoptera pest preventive effect; based on stomach poison function; insect stops taking food fast; very fast vigor is lost back and is told; muscular paralysis is made, remarkable Developing restraint because continuing decalcification, dead in 24 ~ 72 hours.
Bromine cyanogen insect amide, English common name: cyantraniliprole, the bromo-1-(3-chloro-2-pyridyl of chemical name: 3-)-N-[4-cyano group-2 methyl-6-[(methylamino) hydroxyl] phenyl]-1H-pyrazoles-5-formamide, it is E.I.Du Pont Company's second generation ryanodine receptor inhibitor insecticides that success is developed after Rynaxypyr, bromine cyanogen insect amide is formed by the various polar groups changed on phenyl ring, have more efficient, applicable crops is more extensive, can effectively prevent and treat Lepidoptera, Semiptera and coleopteran pest.
Fipronil bisamide, trade name ridge is sung, English common name: flubendiamide; the iodo-N ' of chemical name: 3--(2-mesyl-1,1-dimethyl ethane base-N-{1,2; the chloro-1-(trifluoromethyl of 2,2-tetra-) ethyl]-O-tolyl } phthalamide.Researched and developed by Nihon Nihyaku Co., Ltd, belong to phthalic diamides insecticide.Almost to all Lepidoptera class pests, all there is good activity, and speed of action is fast, the lasting period is long.Especially to rice-stem borer and leaf roll snout moth's larva preventive effect remarkable.
Phyllotreta striolata belongs to coleoptera, Chrysomelidae insect, the brassicaceous vegetable such as main harm wild cabbage, cauliflower, Chinese cabbage, tender flower stalk, radish, turnip, rape.Directly work the mischief to plant with adult and larva two worm states, adult food leaf, bud and tender pod, larva is harmful dish root only, and moth food root skin, bites fibrous root broken, blade is wilted withered.Phyllotreta striolata generally seriously occurs in China, resistance is created to most pharmaceutical agents at present, particularly at south China vegetables flake, vegetable grower need go and buy Chinese medicine control everyday, effect is still undesirable, is badly in need of invention a kind of to phyllotreta striolata preventive effect is good, the lasting period is long, drug cost is low, the insecticide of safety nuisance free.
Soil insect refers to the insect of foot end of causing harm in soil, seed, seedling or nearly soil table stem, and kind is a lot, mainly contains mole cricket, grub, wireworm etc.All distribution is had in China various places.After crops etc. are injured, the lighter wilts, growth retardation, and heavy dries up and extremely, cause the disconnected ridge that is short of seedling, so that the underproduction.The pesticidal effects of current control soil insect is all not satisfactory, is badly in need of a kind of new insecticide of invention.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, remarkable synergy, the Pesticidal combination containing fosthiazate and ryanodine receptor inhibitor insecticides of good disinsection effect.
Another object of the present invention is to provide the application of above-mentioned Pesticidal combination in control phyllotreta striolata and soil insect.
In order to solve in agricultural production the problem of preventing and treating phyllotreta striolata and soil insect difficulty, technical scheme of the present invention solves like this:
A kind of Pesticidal combination containing fosthiazate and ryanodine receptor inhibitor insecticides, Pesticidal combination active component is the first active component fosthiazate, second active component is be selected from the Rynaxypyr of ryanodine receptor inhibitor insecticides, bromine cyanogen insect amide or fipronil bisamide, the weight ratio of the first active component and the second active component is 1:10 ~ 20:1, be preferably 1:5 ~ 10:1, be more preferably 1:3 ~ 3:1.
The cumulant of the first active component and the second active component is 3% ~ 80% of described composition total weight, is preferably 5% ~ 70%.
The present invention is missible oil, suspended emulsion or granule containing the Pesticidal combination of fosthiazate and ryanodine receptor inhibitor insecticides according to the preparation formulation that method known in those skilled in the art can be prepared.
For missible oil, those skilled in the art are familiar with the corresponding auxiliary agent of use and complete the present invention very much.Emulsifier is as calcium dodecyl benzene sulfonate (agriculture breast 500#), Nongru-700 #(common name: alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201#, this dish-60#(common name: Span60), Tween-60 #(common name: polyoxyethylene sorbitan stearate), TX-10(common name: octyl phenol polyoxyethylene (10) ether), agriculture breast 1601#(common name: triphenoethyl benzene phenol polyoxyethylene polyoxypropylene block polymer), agriculture breast 600#, agriculture breast 400# in one or more, stabilizing agent as in triphenyl phosphite, triphenyl phosphate, epoxychloropropane, aceticanhydride one or more, solvent as in dimethylbenzene, toluene, solvent naphtha (S-150, S-180, S-200), toluene, methyl alcohol, dimethyl formamide, 1-METHYLPYRROLIDONE, cyclohexanone, acetone, dimethyl sulfoxide (DMSO) one or more.
To suspended emulsion, spendable auxiliary agent has: dispersant such as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate (dispersing agent NNO), Huntsman Corporation of the TERSPERSE2425(U.S. produce, alkyl naphthalene sulfonic acid salt) in one or more; Emulsifier is as Nongru-700 #(common name: alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201, this dish-60#(common name: sorbitan monostearate), Tween-60 #(common name: sorbitan monostearate APEO), agriculture breast 1601#(common name: phenethyl phenol polyoxyethylene poly-oxygen propylene aether), triphen ethyl phenol polyoxyethylene groups ether phosphate, Huntsman Corporation of the TERSPERSE 4894(U.S. produce) in one or more; Wetting agent as in alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE2500 one or more; Solvent: one or more in dimethylbenzene, toluene, cyclohexanone, acetone, ethyl acetate, solvent naphtha (S-150, S-180, S-200); Thickener as in xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate one or more; Preservative as in formaldehyde, benzoic acid, Sodium Benzoate one or more; Defoamer is as organic silicon defoamer; Antifreezing agent as ethylene glycol, propane diols, glycerine, urea, inorganic salts as in sodium chloride one or more; Stabilizing agent as in triphenyl phosphite, triphenyl phosphate, epoxychloropropane, aceticanhydride one or more; Water is deionized water.
To granule, spendable auxiliary agent has: carrier is as clay, kaolin, talcum, calcium carbonate, diatomite, corn starch, alumina silicate, attapulgite etc.; Dispersant as in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate one or more; Wetting agent as in alkyl sulfate, alkylsulfonate, naphthalene sulfonate one or more; Stabilizing agent as in such as triphenyl phosphite, triphenyl phosphate, epoxychloropropane, aceticanhydride one or more; Adhesive as in polyvinyl alcohol, dextrin, polyvinylpyrrolidone one or more.
Current fosthiazate is used for preventing and treating Plant nematode, does not also apply on control phyllotreta striolata and soil insect, and ryanodine receptor inhibitor insecticides is used for preventing and treating lepidoptera pest, does not also apply on control phyllotreta striolata and soil insect.In order to solve the problem of phyllotreta striolata and controlling underground pest difficulty in agricultural production, inventor is through a large amount of lab screenings and field control effectiveness test, find after fosthiazates different for the mechanism of action and Rynaxypyr, bromine cyanogen insect amide or fipronil bisamide mixture, to phyllotreta striolata with controlling underground pest is effective, the lasting period is long, there is obvious synergistic effect, can use cost be reduced, high to crop safety, meet the security requirement of pesticidal preparations.The present invention has higher insecticidal activity to phyllotreta striolata, soil insect, effectively can solve the problem of current phyllotreta striolata and controlling underground pest difficulty, for fully developing medicament novelty teabag, extending its service life and having important function.
Embodiment
In order to prevent and treat the flea beetle on vegetables, inventor has carried out mutual composite synergy with fosthiazate and Rynaxypyr, bromine cyanogen insect amide or fipronil bisamide and has studied.Test adopts phyllotreta striolata to be tested object, and concrete grammar is:
Phyllotreta striolata (Striped flea beetle), belongs to coleoptera, Chrysomelidae.By inventor, former medicine is mixed with the test medicine of needs, test method is with reference to " People's Republic of China (PRC) agricultural industry criteria NY/T1154.6-2006 ".First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on the basis of preliminary experiment result, flea beetle lethality sets by geometric progression in the scope of 5% ~ 90%).Examination worm is the phyllotreta striolata adult of picking up from field, and indoor feeding, after one week, selects the adult of uniformity, in the diameter 15 centimetres of access storing Brassica campestris leaves, the cylinder of dark 30 centimetres.Every socket joint 30 flea beetles.Bind up with gauze below cylinder and continue to employ the osculum that flea beetle can be shaked out of rubber tying, under 50PSI pressure, aiming at cylinder internal spraying with potter spray tower, each spray cylinder, every ware spraying liquid 5ml.Sprayed and built above cylinder, after static 10 minutes by flea beetle from below opening part shake out, and to raise by the triangular flask being placed in 200ml together with medicine cabbage heart leaf.Blank spray equivalent clear water.25 DEG C, cultivate in 12H/12H illumination box, within 48 hours, check dead borer population, calculate lethality.By the linear regression analysis between the probit value of lethality and the logarithm value of series concentration, obtain the EC of each medicament
50value, calculates the co-toxicity coefficient (CTC) of mixture by the abundant method of Sun Yun, evaluate the activity of reagent agent to examination worm with this.The co-toxicity coefficient (CTC) >=120 of complex preparation shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
Toxicity Determination result shows: fosthiazate and Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide are that 1:10 ~ 20:1 is mixed with weight ratio has good virulence to phyllotreta striolata, all having good synergistic effect, is that 1:5 ~ 10:1 synergy is the most remarkable especially with weight ratio.
In order to prevent and treat the grub on upland grain, inventor is with fosthiazate and ryanodine receptor inhibitor insecticides: Rynaxypyr, bromine cyanogen insect amide or fipronil bisamide have carried out mutual composite synergy and studied.Test adopts wheat Holotrichia oblita to be tested object, and concrete grammar is:
Holotrichia oblita Holotrichia oblita, belong to Insecta coleoptera Scarabaeoidea, larva cries grub.By inventor, former medicine is mixed with the test medicine of needs, test method is with reference to " People's Republic of China (PRC) agricultural industry criteria NY/T1154.15-xxxx ".First single dose and each Mixed Pharmacy are arranged 5 variable concentrations gradients (on the basis of preliminary experiment result, grub lethality sets by geometric progression in the scope of 5% ~ 90%).Examination worm be indoor feeding 2 age grub larva, soak into the liquid 10s and take out, suck unnecessary liquid with filter paper, often process 4 times and repeat, often repeat to soak worm 15, and establish and do not contain the process of medicament as blank.Be transferred to by examination worm and fresh peanut leaf or a small amount of potato block etc. be housed as in the glass tube of food, the mouth of pipe hides with the black cloth of humidity, is placed in (25 ± 1) DEG C, relative moisture is raise under 60% ~ 80% condition and observation.Process latter 72 hours investigation examination worm death condition, calculate lethality.By the linear regression analysis between the probit value of lethality and the logarithm value of series concentration, obtain the EC of each medicament
50value, calculates the co-toxicity coefficient (CTC) of mixture by the abundant method of Sun Yun, evaluate the activity of reagent agent to examination worm with this.
The co-toxicity coefficient (CTC) >=120 of complex preparation shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
Toxicity Determination result shows: fosthiazate and Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide are that 1:10 ~ 20:1 is mixed with weight ratio has good virulence to grub, all having good synergistic effect, is that 1:5 ~ 10:1 synergy is the most remarkable especially with weight ratio.
Below in conjunction with embodiment, content of the present invention is described further.
Example of formulations 1
Take 75% fosthiazate, 5% Rynaxypyr, 4% agriculture breast 500#, 2% agriculture breast 600#, 3% agriculture breast 2201#, 1% triphenyl phosphite, 2% dimethyl sulfoxide (DMSO), dimethylbenzene add to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 80% fosthiazate Rynaxypyr missible oil completely afterwards.
Example of formulations 2
Take 60% fosthiazate, 3% bromine cyanogen insect amide, 4% agriculture breast 500#, 2% agriculture breast 600#, 3% agriculture breast 2201#, 3% triphenyl phosphite, 10% dimethyl formamide, solvent naphtha S-180 add to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 63% fosthiazate bromine cyanogen insect amide missible oil completely afterwards.
Example of formulations 3
Take 30% fosthiazate, 6% fipronil bisamide, 3% agriculture breast 500#, 4% agriculture breast 600#, 5% dimethyl formamide, 3% triphenyl phosphite, S-200 add to 100% weight portion.Above-mentioned raw materials is through mixing, and stirring and dissolving is obtained 36% fosthiazate fipronil bisamide missible oil completely afterwards.
Example of formulations 4
Take 30% fosthiazate, 10% Rynaxypyr, 2.5% triphen ethyl phenol polyoxyethylene groups ether phosphate, 1.5% dispersing agent NNO, 4% Huntsman Corporation of the TERSPERSE4894(U.S. produces), 10% toluene, 3.5% this dish-60#, 3.5% Tween-60 #, 1% Huntsman Corporation of the TERSPERSE2500(U.S. produces), 2% aluminium-magnesium silicate, 0.2% xanthans, 5% ethylene glycol, 1% epoxychloropropane, 0.3% benzoic acid, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product Company), deionized water adds to 100% weight portion.Operating procedure: 1, in above-mentioned raw materials fosthiazate and dissolution with solvents completely after add emulsifier and stabilizing agent mixes, 2, unclassified stores is through mixing, 3, drop in 2 materials by mixing material in 1, high speed shear dispersion 30min, with 40% fosthiazate Rynaxypyr suspended emulsion obtained after sand mill sand milling.
Example of formulations 5
Take 15% fosthiazate, 15% bromine cyanogen insect amide, 1% dispersing agent NNO, Huntsman Corporation of the 1%TERSPERSE2425(U.S. produces), 5% cyclohexanone, 3% solvent naphtha S-180,2.5% agriculture breast 1601#, 3.5% Tween-60 #, 1% alkylphenol-polyethenoxy base ether phosphate, 2% polyvinyl alcohol, 0.2% xanthans, 5% ethylene glycol, 3% triphenyl phosphite, 0.3% Sodium Benzoate, 0.5% silicone defoaming agent, deionized water adds to 100% weight portion.Operating procedure: 1, in above-mentioned raw materials fosthiazate and dissolution with solvents completely after add emulsifier and stabilizing agent mixes, 2, unclassified stores is through mixing, 3, drop in 2 materials by mixing material in 1, high speed shear dispersion 30min, with 30% fosthiazate bromine cyanogen insect amide suspended emulsion obtained after sand mill sand milling.
Example of formulations 6
Take 3% fosthiazate, 30% fipronil bisamide, 2% sodium lignin sulfonate, 1%TERSPERSE 2425,5% dimethylbenzene, 5% ethyl acetate, 3% Nongru-700 #, 3.5% Tween-60 #, 2% TERSPERSE2500,1% aluminium-magnesium silicate, 0.2% xanthans, 5% propane diols, 1% epoxychloropropane, 0.3% benzoic acid, 0.5% silicone defoaming agent, deionized water adds to 100% weight portion.Operating procedure: 1, in above-mentioned raw materials fosthiazate and dissolution with solvents completely after add emulsifier and stabilizing agent mixes, 2, unclassified stores is through mixing, 3, drop in 2 materials by mixing material in 1, high speed shear dispersion 30min, with 33% fosthiazate fipronil bisamide suspended emulsion obtained after sand mill sand milling.
Example of formulations 7
Take 2% fosthiazate, 1% Rynaxypyr, 3% sodium lignin sulfonate, 2% neopelex, 3% polyvinyl alcohol, 3% triphenyl phosphite, kaolin adds to 100% weight portion.Add water mentioned component kneading, uses pinch-out granulator pinch out and be shaped, afterwards by particle fluid-bed drying, and adjustment particle size, obtained 3% fosthiazate Rynaxypyr granule.
Example of formulations 8
Take 20% fosthiazate, 2% bromine cyanogen insect amide, 2% neopelex, 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% polyvinylpyrrolidone, 3% triphenyl phosphite, attapulgite add to 100% weight portion.Above-mentioned raw materials is mediated through mixing and water adding, uses pinch-out granulator pinch out and be shaped, afterwards by particle fluid-bed drying, and adjustment particle size, obtained 22% fosthiazate bromine cyanogen insect amide granule.
Example of formulations 9
Take 4% fosthiazate, 12% fipronil bisamide, 2% neopelex, 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 3% polyvinylpyrrolidone, 3% triphenyl phosphite, diatomite adds to 100% weight portion.Above-mentioned raw materials is mediated through mixing and water adding, uses pinch-out granulator pinch out and be shaped, afterwards by particle fluid-bed drying, and adjustment particle size, obtained 16% fosthiazate fipronil bisamide granule.
Biological Examples 1: control phyllotreta striolata field trial (soil treatment method)
Phyllotreta striolata (Phyillotreta vittata Fabricius) is the worldwide important pests of brassicaceous vegetable of seriously causing harm, widely distributed in China.Its study on prevention has received the very big concern in world many countries and area.Become insect bite food blade to cause blade-shaped to become hole, incise, affect vegetable growth; Larval feeding root, the epidermis of stripping food dish root, makes plant wilting withered, has a strong impact on the Quality and yield of vegetables.In addition, adult can also propagate soft rot of cabbage.For a long time, control phyllotreta striolata is mainly based on blade face spray medicine, the method often causes residue of pesticide to exceed standard, increase the weight of residue of pesticide and contaminated environment, and larva in soil, pupa and ovum cannot be killed, adult is constantly sprouted wings unearthed causing harm, thus add spray medicine number of times, increase dosage, phyllotreta striolata is caused to improve rapidly the resistance of multiple insecticide as dichlorvos, chlopyrifos, Acetamiprid, cypermethrin etc., cause control efficiency to decline, therefore seek novel, efficient, that low toxic pesticide controls this worm is particularly important.This field trial be intended to clearly containing the Pesticidal combination of fosthiazate and adjacent formamido benzamide insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide for soil treatment, control the generation of phyllotreta striolata, reach the effect improving control efficiency, reduce times for spraying and reduction residue of pesticide.
Inventor has done formulation examples 4(40% fosthiazate Rynaxypyr suspended emulsion in March, 2012 in Zhongshan City, Guangdong Province), example of formulations 5(30% fosthiazate bromine cyanogen insect amide suspended emulsion), example of formulations 9(16% fosthiazate fipronil bisamide granule) prevent and treat phyllotreta striolata field control effectiveness test.Trial crops is a variety of Chinese cabbage, and controlling object is phyllotreta striolata.Experimental field soil is red soil, and fertility is general, the cultivation condition of each community, water and fertilizer management uniformity.Test medicine and dosage refer to table 3.Carried out soil treatment the same day in sowing, every 667 ㎡ mix fine sand 15Kg by design dosage and spread fertilizer over the fields, and sow subsequently.Separately establish blank, often process 4 times and repeat, every plot area 35 ㎡, Gong32Ge community, random district group arranges.
Investigation and statistical method:
Adopt parallel sampling method, every community 5 point, often some investigation 10 strains, the work on totally 50 strain a variety of Chinese cabbages becomes borer population, within after dispenser 7,14,21 days, respectively investigates 1 time.
Drug effect computational methods
Control efficiency (%)=[(check plot borer population-treatment region alive borer population alive)/check plot borer population alive] × 100%.
Result of the test shows, 40% fosthiazate Rynaxypyr suspended emulsion, 30% fosthiazate bromine cyanogen insect amide suspended emulsion, 16% fosthiazate fipronil bisamide granule presses 100g/667 ㎡ respectively, 60g/667 ㎡, 80g/667 ㎡ consumption, soil treatment is carried out before a variety of Chinese cabbage sowing, significant control efficiency is had to phyllotreta striolata, after medicine 7, 14, investigation in 21 days, obviously be better than 30% fosthiazate missible oil 500g/667 ㎡, 20% Rynaxypyr suspending agent 100g/667 ㎡, 20% bromine cyanogen insect amide suspending agent 100g/667 ㎡, 20% fipronil bisamide water dispersible granules 100g/667 ㎡ is to the control efficiency of phyllotreta striolata.
Security survey, duration of test is observed, and all reagent agents, to Growth of Cabbage safety, occur without poisoning phenomenon.
Biological Examples 2: control phyllotreta striolata field trial (foliar spray method)
Also done formulation examples 4(40% fosthiazate Rynaxypyr suspended emulsion in March, 2012 in Zhongshan City, Guangdong Province), example of formulations 5(30% fosthiazate bromine cyanogen insect amide suspended emulsion), example of formulations 3(36% fosthiazate fipronil bisamide missible oil) prevent and treat phyllotreta striolata field control effectiveness test, medicament and dosage refer to table 4.Trial crops is a variety of Chinese cabbage, and breeding time is Seedling Stage, and controlling object is phyllotreta striolata, and on plant, adult amount is larger.If blank, often process and repeat for 4 times, every plot area 30 ㎡, Gong32Ge community, random district group arranges.Be 30kg/667 ㎡ by amount of liquid medicine, adopt manual sprayer evenly to spray, the spraying method enclosed by four circumferential tundish of community.
Investigation and statistical method:
With biological Examples 1, control time is respectively investigate 1 time for after dispenser 1,3,7 day.
Result of the test shows, 40% fosthiazate Rynaxypyr suspended emulsion, 30% fosthiazate bromine cyanogen insect amide suspended emulsion, 15g/667 ㎡ pressed respectively by 36% fosthiazate fipronil bisamide missible oil, 10g/667 ㎡, 20g/667 ㎡ consumption, adopt foliar spray method, significant control efficiency is had to phyllotreta striolata, after medicine 1, 3, investigation in 7 days, obviously be better than 30% fosthiazate missible oil 60g/667 ㎡, 20% Rynaxypyr suspending agent 10g/667 ㎡, 20% bromine cyanogen insect amide suspending agent 10g/667 ㎡, 20% fipronil bisamide water dispersible granules 10g/667 ㎡ is to the control efficiency (table 4) of phyllotreta striolata.
Security survey, duration of test is observed, and all reagent agents, to Growth of Cabbage safety, occur without poisoning phenomenon.
Biological Examples 1,2 result shows, after fosthiazate and Rynaxypyr, bromine cyanogen insect amide or fipronil bisamide mixture, significantly improves the control efficiency to phyllotreta striolata, synergistic effect is remarkable, reducing dosage, to Growth of Cabbage safety, is the favourable agents of control phyllotreta striolata.
Biological Examples 3: control peanut soil pest field trial
Inventor has carried out example of formulations 4(40% fosthiazate Rynaxypyr suspended emulsion in 2011 in Xinxiang City of province of Henan Province), example of formulations 8(22% fosthiazate bromine cyanogen insect amide granule), example of formulations 9(16% fosthiazate fipronil bisamide granule) prevent and treat peanut soil pest field trial.Trial crops is peanut, and kind is seaflower, controlling object soil insect (grub accounts for 95.4%, and mole cricket, cutworm, wireworm account for 4.6%).Test is located at bridge Beixiang, Yuanyang County, and the soil texture is medium loam, and long-term soil insect is serious.Carry out soil treatment in the sowing same day (June 8), every 667 ㎡ mix fine sand 15Kg by design dosage and spread fertilizer over the fields, and sow subsequently, adopt artificial dibbling, and line-spacing 30cm, cave are apart from 20cm.Often process and repeat for 4 times, every plot area 66.6 ㎡, Gong32Ge community, random district group arranges.
Investigation and statistical method, investigate 2 times altogether, and first time, method was " Z " font 5 sampling in every experimental plot, often some 50cm × 50cm, degree of depth 30cm, records worm amount and worm kind in unit are in detail at after planting 40 days investigation vermins-proof effects.Second time is investigated before results, and take 5 point samplings, get 10 piers at often, every community is totally 50 pier peanuts, the killed situation of investigation pod, calculates fruit retention rate according to pod rate of being injured.The impact of to the front irregularly observation of results each treatment region, peanut being emerged after peanut seeding and grow and the impact on other insect.
Control efficiency (%)=[(blank district borer population-treatment region alive borer population alive)/blank district borer population alive] × 100
Fruit retention rate (%)=[(blank district killed pod rate-treatment region killed pod rate) the killed pod rate in/blank district] × 100.
Field trial shows: 40% fosthiazate Rynaxypyr suspended emulsion, 22% fosthiazate bromine cyanogen insect amide granule, 16% fosthiazate fipronil bisamide granule have more significant control efficiency to peanut soil pest (mainly grub), consumption is respectively 100g/667 ㎡, 400g/667 ㎡, 80g/667 ㎡ carry out soil treatment, 96.2%, 93.6%, 94.9% was respectively to the preventive effect of soil insect (mainly grub) in after medicine 40 days, investigate during results, 96.9%, 91.9%, 94.1% is respectively to peanut fruit retention rate.Obviously be better than contrast medicament 30% fosthiazate missible oil 500g/667 ㎡, 20% Rynaxypyr suspending agent 100g/667 ㎡, 20% bromine cyanogen insect amide suspending agent 100g/667 ㎡, 20% fipronil bisamide water dispersible granules 100g/667 ㎡ to the control efficiency of peanut soil pest and fruit retention effect (shown in table 5).
Security survey, chemicals treatment is after planting irregularly observed to harvest time, and all reagent agents, to peanut growth safety, occur without poisoning phenomenon.
Result of the test significantly improves the control efficiency to peanut soil pest, reduces dosage, to peanut growth safety after showing fosthiazate and Rynaxypyr, bromine cyanogen insect amide or fipronil bisamide mixture.
From above embodiment, first active component fosthiazate and the second active component ryanodine receptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide or fipronil bisamide combine composite, can be made into missible oil, suspended emulsion, granule formulation, significant control efficiency is had to the phyllotreta striolata of damage to crops and soil insect, have that dosage is few, control efficiency advantages of higher, save drug cost, and good to crop safety, have wide practical use on therefore producing.
In sum, composition of the present invention is employing two kinds of active component compound schemes, its activity and insecticidal effect are not the simple superposition of each composition activity, compared with existing unitary agent, except there is significant insecticidal effect, and there is significant synergistic effect, preparation less residue, pollution-free to crop, safety is good, meets the security requirement of pesticidal preparations.
Claims (7)
1. contain a Pesticidal combination for lythidathion and ryanodine receptor inhibitor insecticides, it is characterized in that Pesticidal combination active component is lythidathion and bromine cyanogen insect amide, the weight ratio of lythidathion and bromine cyanogen insect amide is 1:10 ~ 20:1.
2. contain the Pesticidal combination of lythidathion and ryanodine receptor inhibitor insecticides according to claim 1, it is characterized in that: the weight ratio of lythidathion and bromine cyanogen insect amide is 1:5 ~ 10:1.
3. contain the Pesticidal combination of lythidathion and ryanodine receptor inhibitor insecticides according to claim 2, it is characterized in that: the weight ratio of lythidathion and bromine cyanogen insect amide is 1:3 ~ 3:1.
4., according to one of any described Pesticidal combination containing lythidathion and ryanodine receptor inhibitor insecticides of claims 1 to 3, it is characterized in that: the cumulant of lythidathion and bromine cyanogen insect amide is 3% ~ 80% of described composition total weight.
5. contain the Pesticidal combination of lythidathion and ryanodine receptor inhibitor insecticides according to claim 4, it is characterized in that: the cumulant of lythidathion and bromine cyanogen insect amide is 5% ~ 70% of described composition total weight.
6. contain the Pesticidal combination of lythidathion and ryanodine receptor inhibitor insecticides according to claim 4, it is characterized in that: described composition is missible oil, suspended emulsion or granule.
7. preventing and treating the application in phyllotreta striolata and soil insect containing the Pesticidal combination of lythidathion and ryanodine receptor inhibitor insecticides described in claim 1.
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| CN201210318054.3A CN102805102B (en) | 2012-08-31 | 2012-08-31 | Disinsection combination containing fosthiazate and ryanodine receptor inhibitor insecticide |
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| CN201310236189XA Division CN103300058A (en) | 2012-08-31 | 2012-08-31 | Insecticidal combination containing fosthiazate and ryanicide acceptor inhibitor type insecticide |
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| CN102805102B true CN102805102B (en) | 2015-02-11 |
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| CN103300058A (en) * | 2012-08-31 | 2013-09-18 | 陕西上格之路生物科学有限公司 | Insecticidal combination containing fosthiazate and ryanicide acceptor inhibitor type insecticide |
| CN105994352A (en) * | 2016-06-21 | 2016-10-12 | 南京华洲药业有限公司 | Composite insecticide composition containing cyantraniliprole and profenofos and application thereof |
| CN111903673A (en) * | 2020-09-01 | 2020-11-10 | 福建省三明市烟草物流有限责任公司 | Diatomite and ryanodine receptor inhibitor insecticidal composition, preparation method thereof and application thereof in preventing and controlling tobacco stem borers |
| CN113912445A (en) * | 2021-10-18 | 2022-01-11 | 河南好年景生物发展有限公司 | Sustained-release pesticide-fertilizer granules for preventing and treating main insect pests of tobacco and preparation method thereof |
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| CN102696673A (en) * | 2012-06-01 | 2012-10-03 | 北京明德立达农业科技有限公司 | Fosthiazate insecticide composition and application thereof |
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| PT1380209E (en) * | 2001-04-17 | 2012-09-27 | Nihon Nohyaku Co Ltd | Pest control agent composition and method of using the same |
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| Title |
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| 鱼尼汀受体作用剂类杀虫剂及其结构特点和机制;张一宾;《农药》;20120331;第51卷(第3期);第157-162页 * |
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Inventor after: He Aihua Inventor after: Hou Jiangli Inventor after: Sun Rui Inventor after: Zhao Haijun Inventor after: Mei Hongyu Inventor after: Kou Pengbin Inventor after: Wu Xiaoyu Inventor after: Lu Hairui Inventor after: Da Puni Inventor after: Liang Bailiang Inventor after: Zhou Dawei Inventor after: Chen Hong Inventor after: Yang Ziyao Inventor after: Li Ping Inventor after: Li Mingfu Inventor after: Feng Jianxiong Inventor after: Zhang Chongbin Inventor after: Shi Xiaolei Inventor after: Zhang Jie Inventor after: Huang Fawei Inventor after: Wei Ting Inventor before: He Aihua Inventor before: Sun Rui Inventor before: Zhao Haijun Inventor before: Mei Hongyu Inventor before: Kou Pengbin Inventor before: Wu Xiaoyu Inventor before: Lu Hairui Inventor before: Da Puni Inventor before: Liang Bailiang Inventor before: Zhou Dawei Inventor before: Yang Ziyao Inventor before: Li Mingfu Inventor before: Li Ping Inventor before: Feng Jianxiong Inventor before: Zhang Chongbin Inventor before: Shi Xiaolei Inventor before: Zhang Jie Inventor before: Huang Fawei Inventor before: Wei Ting Inventor before: Hou Jiangli |
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