CN102657189B - Pesticide composition containing cycloxaprid - Google Patents
Pesticide composition containing cycloxaprid Download PDFInfo
- Publication number
- CN102657189B CN102657189B CN201210139997.XA CN201210139997A CN102657189B CN 102657189 B CN102657189 B CN 102657189B CN 201210139997 A CN201210139997 A CN 201210139997A CN 102657189 B CN102657189 B CN 102657189B
- Authority
- CN
- China
- Prior art keywords
- cycloxaprid
- pesticide
- rynaxypyr
- cotton
- insect amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention discloses a pesticide composition containing cycloxaprid and a ryanodine receptor inhibitor pesticide. The composition comprises the following active ingredients: a first active ingredient, namely cycloxaprid, and a second active ingredient, namely a ryanodine receptor inhibitor pesticide selected from chlorantraniliprole, cyantraniliprole, flubendiamide and clothianidin, wherein the weight ratio of the first active ingredient to the second active ingredient is (1:20)-(20:1). The composition can be prepared into such agriculturally allowable dosage forms as water dispersible granules, wettable powder and suspending agents. The pesticide composition has the following beneficial effects: the pesticide composition has reasonable ingredients, good pesticidal effect and low pesticide cost; the activity and pesticidal effect of the pesticide composition are not simple addition of the activities and pesticidal effects of the ingredients; and compared with the existing single preparations, the pesticide composition has obvious synergistic effect besides the obvious pesticidal effect, has good safety, conforms to the safety requirements of the pesticide preparations and has better control effect on cnaphalocrocis medinalis guenee, nilaparvata lugens, wheat aphids, cotton aphids, cotton bollworms and beet armyworms.
Description
Technical field
The present invention relates to a kind of Pesticidal combination, particularly contain cycloxaprid as the first active component a kind of comprising, be selected from the ryanodine receptor inhibitor insecticides of Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide as the Pesticidal combination of the second active component, belong to technical field of compounded pesticide.
Background technology
Cycloxaprid is a kind of novel anabasine insecticide, by East China University of Science, formulated, chemical name: 9-(6-chloropyridine-3-yl) methyl)-4-nitro-8-oxa--10,11-glyoxalidine also (2,3-a) dicyclo (3,2,1) pungent-3-alkene, English common name: cycloxaprid, chemical molecular formula C
14h
15cIN
4o
3.Insect is had to interior suction, stomach toxicity and action of contace poison, can be used for preventing and treating Homoptera, coleopteran pest on crops, without cross resistance, also effective to lepidoptera pest with Imidacloprid, Acetamiprid, Diacloden etc.This product using dosage is low, environmentally safe, to beneficial organism without harm or endanger minimum.The aphid of the crops such as wheat, cotton, paddy rice, fruit tree, vegetables, plant hopper, aleyrodid, flea beetle etc. are had to higher insecticidal activity.As a kind of novel anabasine insecticide, it is high that cycloxaprid exists use cost after listing, the risk that resistance risk increases gradually.
In recent years, people from Ryanicide class plant for Ryanicide acceptor (ryanodine receptors, RyRs) developed the novel insecticide of a class that acts on Ryanicide acceptor, for insecticide of new generation, the brand-new mechanism of action, and formed new insecticide series of products--Ryanicide acceptor inhibitor insecticides.The principal item that this insecticides is successfully developed at present has Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide etc.
Rynaxypyr; trade name health is wide; English common name: Chlorantraniliprole; the bromo-N-[4-chloro-2-methyl-6-[(of chemical name: 3-methyl-carbamoyl) benzene]-1-(3-chloropyridine-2-yl)-1-hydrogen-pyridine-5-formamide; anthranilamide-based Ryanicide receptor acting agent for E.I.Du Pont Company's exploitation; excellent to lepidoptera pest preventive effect; take stomach poison function as main; insect stops taking food fast; very fast vigor is lost back and is told; because continuing decalcification, make muscular paralysis significantly suppress growth, dead in 24～72 hours.
Bromine cyanogen insect amide, English common name: cyantraniliprole, the bromo-1-(3-chloro-2-pyridyl of chemical name: 3-)-N-[4-cyano group-2 methyl-6-[(methylamino) hydroxyl] phenyl-1]-1-H-pyrazoles-5-formamide, it is E.I.Du Pont Company's second generation Ryanicide acceptor inhibitor insecticides that success is developed after Rynaxypyr, bromine cyanogen insect amide is that the various polar groups by changing on phenyl ring form, have more efficient, applicable crops is more extensive, can effectively prevent and treat Lepidoptera, Semiptera and coleopteran pest.
Fipronil bisamide, trade name ridge song, English common name: flubendiamide, the iodo-N ' of chemical name: 3--(2-mesyl-1,1-dimethyl ethyl group-N-{1,2,2,2-tetrachloro-1-(trifluoromethyl) ethyl]-O-tolyl } phthalamide.By Nihon Nihyaku Co., Ltd, researched and developed, belong to phthalic diamides insecticide.Almost all Lepidoptera class pests are all had to good activity, and speed of action is fast, the lasting period is long.Especially remarkable to rice-stem borer and leaf roll snout moth's larva preventive effect.
Thiophene insect amide, test code number JS 9117, the bromo-N-{4-chloro-2-methyl of chemical name: 3--6-[2-(5-amino-1,3,4-thiadiazoles)] phenyl }-1-(3-chloropyridine-2-yl)-1H-pyrazoles-5-formamide is the Novel ortho heterocycle benzamide compound that Jiangsu Prov. Inst. of Agricultural Chemicals's initiative is found.This compound can have efficiently with the insecticide in the fields such as preparation agricultural, gardening, low toxicity, environment amenable advantage, high to other like products of lepidoptera pest specific activity.
As a kind of novel anabasine insecticide, it is high that cycloxaprid exists use cost after listing, and the risk that resistance risk increases is gradually efficient to homoptera pest, to the poor defect of lepidoptera pest drug effect; Ryanicide acceptor inhibitor insecticides is effective to lepidoptera pest, but quick-acting is general, and to other insect weak effects beyond Lepidoptera, use year by year, resistance development is very fast, and inventor surprisingly finds uses that is mixed such as cycloxaprid and Ryanicide acceptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amides, there is significant synergistic effect, can reduce use cost, when various pests occurs, accomplish double controlling simultaneously, high to crop safety.
Summary of the invention
The object of the present invention is to provide a kind of component reasonable, significantly synergy, good disinsection effect, the Pesticidal combination containing cycloxaprid and ryanodine receptor inhibitor insecticides that drug cost is low.
Another object of the present invention is to provide the application of above-mentioned Pesticidal combination.
In order to overcome the defect of existing unitary agent, technical scheme of the present invention is to solve like this:
A Pesticidal combination containing cycloxaprid and Ryanicide acceptor inhibitor insecticides, comprising:
A) the first active component cycloxaprid;
B) the second active component is selected from the Ryanicide acceptor inhibitor insecticides of Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide;
The weight ratio of the first active component and the second active component is 1:20～20:1, is preferably 1:15～15:1, and more preferably 1:10～10:1, most preferably is 1:5～5:1.
The cumulant of the first active component and the second active component is 3%～80% of described composition total weight, is preferably 5%～70%, and the size of active component cumulant is also closely related with formulation, as the active component cumulant of suspending agent, is no more than 55%.
The preparation formulation that the present composition can be prepared according to method known in those skilled in the art is water dispersible granules, wetting powder, suspending agent.
For water dispersible granules, those skilled in the art are familiar with the corresponding auxiliary agent of use and complete the present invention very much.Dispersant as in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate one or more; Wetting agent as in alkyl sulfate, alkylsulfonate, naphthalene sulfonate one or more; Disintegrant as in ammonium sulfate, urea, sucrose, glucose one or more; Binding agent is as one or more in diatomite, corn starch, PVA, carboxymethyl (ethyl) cellulose family; Filler as diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To wetting powder, spendable auxiliary agent has: dispersant as in polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate one or more; Wetting agent as in alkyl sulfate, alkylsulfonate, naphthalene sulfonate one or more; Filler as ammonium sulfate, urea, sucrose, glucose, diatomite, kaolin, white carbon, fine particle calcium carbonate, talcum powder, attapulgite, potter's clay one or more.
To suspending agent, spendable auxiliary agent has: dispersant is produced as polycarboxylate, lignosulfonates, alkylnaphthalene sulfonate (dispersing agent NNO), TERSPERSE 2020(U.S. Huntsman Corporation, alkyl naphthalene sulfonic acid salt) in one or more; Polyoxyethylene sorbitan stearate), agriculture breast 1601#(common name Span60), Tween-60 #(common name alkyl phenol formaldehyde resin polyoxyethylene ether), agriculture breast 2201, this dish-60#(common name emulsifier is as Nongru-700 #(common name:::: one or more triphen ethyl-phenol polyoxyethylene polyoxypropylene block polymer), in TERSPERSE 4894; Wetting agent as in alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, alkylphenol-polyethenoxy base ether phosphate, phenethyl phenol polyethenoxy base ether phosphate, alkyl sulfate, alkylsulfonate, naphthalene sulfonate, TERSPERSE 2500 one or more; Thickener as in xanthans, polyvinyl alcohol, bentonite, aluminium-magnesium silicate one or more; Preservative as in formaldehyde, benzoic acid, Sodium Benzoate one or more; Stabilizing agent as in epoxidized soybean oil, epoxychloropropane, triphenyl phosphate one or more; Defoamer is as organic silicon defoamer; Antifreezing agent as ethylene glycol, propane diols, glycerine, urea, inorganic salts as in sodium chloride one or more; Water is deionized water.
Component of the present invention is reasonable, good disinsection effect, and drug cost is low, and its active and insecticidal effect is not the simple superposition of each composition activity, but has significant synergistic effect and doublely control effect, good to crop safety, meets the security requirement of pesticidal preparations.The present invention has higher insecticidal activity to paddy rice rice leaf roller, brown plant-hopper, wheat aphid, cotton aphid, cotton cotton bollworm, vegetables beet armyworm.
Embodiment
In order to prevent and treat paddy rice rice leaf roller, cotton cotton bollworm, the beet armyworm in agricultural production, inventor has carried out mutual combine experiment with cycloxaprid and the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.Concrete grammar is:
Subjects: rice leaf roller formal name used at school Cnaphalocrocis medinalis Guenee, the vertical volume of another name snout moth's larva, tortrix moth, Lepidoptera, Pyralidae.Cotton bollworm Heliothis armigera, Lepidoptera, Noctuidae.Beet armyworm Spodoptera exigua, Lepidoptera, Noctuidae.Former medicine is mixed with to the test medicine needing, test method is with reference to the agricultural industry criteria NY/T1154.2-2006 > > of the < < People's Republic of China (PRC).First single dose and each Mixed Pharmacy are arranged to 5 variable concentrations gradients (on the basis of preliminary experiment result, rice leaf roller lethality is set by geometric progression in 5%～90% scope).Examination worm is rice leaf roller, cotton bollworm, the beet exigua larvae that field gathers, in laboratory, select the larva of uniformity in the length of time, hungry 4～8 hours, with the card punch of 1 centimetre of diameter, beat and get leaf dish, put into culture dish, and note moisturizing. with capillary dropper from low concentration, every leaf dish point 1 μ L～2 μ L liquid that drips, after solvent evaporates and another sheet scribble the involutory malicious leaf dish of folder of making of the leaf dish of gelatinized corn starch, make in the hole of the complete 12Kong of being put in tissue culturing plate.Every processing 4 times repeats, and often repeats to be no less than 12 malicious leaf dish of folder, and establishes not containing the processing of the corresponding organic solvent of medicament in contrast.In each hole of tissue culturing plate, connect 1 examination worm, be placed under normal condition and cultivate.Connect worm after 2～4 hours, wait trying worm, taken food after pastille leaf dish, in cultivating plate hole, add clean feed to continue to raise to investigation, eliminate the examination worm that has not eaten an intact leaves dish, within 24 hours, check dead borer population, calculate lethality.By the linear regression analysis between the probit value of lethality and the logarithm value of series concentration, obtain the LC of each medicament
50value, with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, evaluates the activity of reagent agent to examination worm with this.
The co-toxicity coefficient of complex preparation (CTC) >=120 shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
Toxicity Determination result shows: cycloxaprid be take weight ratio has good virulence as 1:20～20:1 is mixed to rice leaf roller, cotton bollworm, beet armyworm with the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide, all has significant synergistic effect.
In order to prevent and treat the rice hoppers in agricultural production, inventor has carried out mutual composition research with cycloxaprid with the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.It is tested object that test adopts brown plant-hopper, and concrete grammar is:
Brown plant-hopper formal name used at school Nilaparvata lugens, Homoptera, Delphacidae.Former medicine is mixed with to the test medicine needing, test method is with reference to the agricultural industry criteria NY/T1154.7-2006 > > of the < < People's Republic of China (PRC).First single dose and each Mixed Pharmacy are arranged to 5 variable concentrations gradients (on the basis of preliminary experiment result, brown plant-hopper lethality is set by geometric progression in 5%～90% scope).Examination worm is rice fulgorid (brown planthopper) ovum that picks up from field, in greenhouse, with rice seedlings, raised for 3 generations, select uniformity 3 age nymph, be pressed into the culture dish of putting rice seedling (processing with cotton ball moisturizing) diameter 12cm, every ware connects and anaesthetizes 30 of nymphs, every processing connects 4 culture dishes, with potter spray tower, under 50PSI pressure, spray, a ware of each spray, every ware spraying liquid 3ml, after insect revives, puts into 12H/12H illumination box by the culture dish of processing and cultivates, within 72 hours, check dead borer population, calculate lethality.Blank spray equivalent clear water.By the linear regression analysis between the probit value of lethality and the logarithm value of series concentration, obtain the LC of each medicament
50value, with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, evaluates the activity of reagent agent to examination worm with this.
The co-toxicity coefficient of complex preparation (CTC) >=120 shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
Toxicity Determination result shows: cycloxaprid and Ryanicide acceptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide, the weight ratio of take has good virulence as 1:20～20:1 is mixed to rice fulgorid, all has significant synergistic effect.
In order to prevent and treat the wheat aphid in agricultural production, inventor has carried out mutual composition research with cycloxaprid and the Ryanicide acceptor inhibitor insecticides that is selected from Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide.It is tested object that test adopts English grain aphid, and concrete grammar is:
English grain aphid (Sitobion avenae), belongs to Homoptera, Aphidiadae.Former medicine is mixed with to the test medicine needing, test method is with reference to the agricultural industry criteria NY/T1154.6-2006 > > of the < < People's Republic of China (PRC).First single dose and each Mixed Pharmacy are arranged to 5 variable concentrations gradients (on the basis of preliminary experiment result, aphid lethality is set by geometric progression in 5%～90% scope).Examination worm is the aphid of picking up from field, in laboratory, select the larva of uniformity, put into blade-carrying culture dish, every ware 40 cephalont, 4 culture dishes of every processing, repeat 3 times, with potter spray tower, under 50PSI pressure, spray, spray a ware at every turn, every ware spraying liquid 3ml, then the culture dish of processing is put into 12H/12H illumination box and cultivate, within 48 hours, check dead borer population, calculate lethality.Blank spray equivalent clear water.By the linear regression analysis between the probit value of lethality and the logarithm value of series concentration, obtain the LC of each medicament
50value, with the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun mixture, evaluates the activity of reagent agent to examination worm with this.
The co-toxicity coefficient of complex preparation (CTC) >=120 shows as synergistic effect; CTC≤80 show as antagonism; 80 < CTC < 120 show as summation action.
Toxicity Determination result shows: cycloxaprid and Ryanicide acceptor inhibitor insecticides Rynaxypyr, bromine cyanogen insect amide, fipronil bisamide, thiophene insect amide, the weight ratio of take has good virulence as 1:20～20:1 is mixed to English grain aphid, all has significant synergistic effect.
FORMULATION EXAMPLE 1
Take 20% cycloxaprid, 20% Rynaxypyr, 4% Morwet D-425(alkyl naphthalene sulfonic acid condensation polymer sodium salt, Akzo Nobel N.V. produces), 3% dispersing agent NNO (alkylnaphthalene sulfonate formaldehyde condensation products), 2% Nekal BX (nekal), 2% K-12(lauryl sodium sulfate), 2% corn starch, 2% sucrose, kaolin add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 40% cycloxaprid Rynaxypyr water dispersible granules.
FORMULATION EXAMPLE 2
Take 3% cycloxaprid, 60% Rynaxypyr, 4% TERSPERSE 2700(polycarboxylate, U.S. Huntsman Corporation produces), 2% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% corn starch, 5% ammonium sulfate, attapulgite add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 63% cycloxaprid Rynaxypyr water dispersible granules.
FORMULATION EXAMPLE 3
Take 5% cycloxaprid, 75% bromine cyanogen insect amide, 1% TERSPERSE 2700,1% dispersing agent NNO, 1% Nekal BX, 1%K-12,1% carboxymethyl cellulose, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 80% cycloxaprid bromine cyanogen insect amide water dispersible granules.
FORMULATION EXAMPLE 4
Take 36% cycloxaprid, 18% fipronil bisamide, 3% TERSPERSE 2700,3% dispersing agent NNO, 2% Nekal BX, 2%K-12,1% carboxymethyl cellulose, 5% urea, diatomite and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 54% cycloxaprid fipronil bisamide water dispersible granules.
FORMULATION EXAMPLE 5
Take 15% cycloxaprid, 45% thiophene insect amide, 4% Morwet D-425,3% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% corn starch, 5% sucrose, kaolin and add to 100% weight portion.The method of the frequent regulation of above-mentioned raw materials water intaking dispersible granule mixes, ultra micro air-flow crushing, mixing, granulation step are produced 60% cycloxaprid thiophene insect amide water dispersible granules.
FORMULATION EXAMPLE 6
Take 25% cycloxaprid, 45% Rynaxypyr, 5% calcium lignosulfonate, 2% Nekal BX, 2%K-12,5% White Carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 70% cycloxaprid Rynaxypyr wetting powder after air-flow crushing.
FORMULATION EXAMPLE 7
Take 36% cycloxaprid, 12% bromine cyanogen insect amide, 4% calcium lignosulfonate, 3% TERSPERSE 2700,2% Nekal BX, 2%K-12,3% White Carbon black, fine particle calcium carbonate and add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 48% cycloxaprid bromine cyanogen insect amide wetting powder after air-flow crushing.
FORMULATION EXAMPLE 8
Take 50% cycloxaprid, 2.5% fipronil bisamide, 2% calcium lignosulfonate, 2% dispersing agent NNO, 1% Nekal BX, 1%K-12, attapulgite and add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 52.5% cycloxaprid fipronil bisamide wetting powder after air-flow crushing.
FORMULATION EXAMPLE 9
Take 10% cycloxaprid, 50% fipronil bisamide, 4% calcium lignosulfonate, 4% dispersing agent NNO, 2% Nekal BX, 2%K-12,3% White Carbon black, attapulgite and add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 60% cycloxaprid fipronil bisamide wetting powder after air-flow crushing.
FORMULATION EXAMPLE 10
Take 9% cycloxaprid, 36% thiophene insect amide, 5% calcium lignosulfonate, 2% Nekal BX, 2%K-12,5% White Carbon black, kaolin and add to 100% weight portion.Above-mentioned raw materials, through mixing, makes 45% cycloxaprid thiophene insect amide wetting powder after air-flow crushing.
FORMULATION EXAMPLE 11
Take 12% cycloxaprid, 24% Rynaxypyr, 4% TERSPERSE 4894(U.S. Huntsman Corporation produces), 1.5% TERSPERSE 2500(U.S. Huntsman Corporation produces), 2% TERSPERSE 2020(U.S. Huntsman Corporation produces), 1% aluminium-magnesium silicate, 0.2% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent (trade name: s-29 Nanjing "four news" (new ideas applied chemistry product company produces), 2% triphenyl phosphate, deionized water adds to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 36% cycloxaprid Rynaxypyr suspending agent after sand mill sand milling.
FORMULATION EXAMPLE 12
Take 6% cycloxaprid, 36% bromine cyanogen insect amide, 5%TERSPERSE 4894,2%TERSPERSE 2500,3%TERSPERSE 2020,0.2% xanthans, 5% propane diols, 0.5% benzoic acid, 1% epoxychloropropane, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 42% cycloxaprid bromine cyanogen insect amide suspending agent after sand mill sand milling.
FORMULATION EXAMPLE 13
Take 2% cycloxaprid, 3% bromine cyanogen insect amide, 2%TERSPERSE 2020,2% this dish-60#, 2% Tween-60 #, 1%TERSPERSE 2500,0.5% white carbon, 0.3% xanthans, 5% ethylene glycol, 0.5% benzoic acid, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 5% cycloxaprid bromine cyanogen insect amide suspending agent after sand mill sand milling.
FORMULATION EXAMPLE 14
Take 5% cycloxaprid, 35% fipronil bisamide, 1%TERSPERSE 2020,3% agriculture breast 1601#, 2% agriculture breast 2201#, 1%TERSPERSE 2500,0.3% xanthans, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.High speed shear is disperseed 30min, with making 40% cycloxaprid fipronil bisamide suspension agent after sand mill sand milling.
FORMULATION EXAMPLE 15
Take 40% cycloxaprid, 10% thiophene insect amide, 4%TERSPERSE 4894,1.5%TERSPERSE 2500,1%TERSPERSE 2020,0.2% aluminium-magnesium silicate, 5% ethylene glycol, 0.5% formaldehyde, 0.5% silicone defoaming agent, 1% epoxychloropropane, deionized water and add to 100% weight portion.Above-mentioned raw materials is through mixing, and high speed shear is disperseed 30min, with making 50% cycloxaprid thiophene insect amide suspending agent after sand mill sand milling.
Biological Examples 1: control paddy rice rice leaf roller, rice fulgorid field trial
Inventor has carried out formulation examples 1(40% cycloxaprid Rynaxypyr water dispersible granules in Leizhou City, 12 in May, 2011 Guangdong Province), formulation examples 14(40% cycloxaprid fipronil bisamide suspension agent) control paddy rice rice leaf roller, rice fulgorid field control effectiveness test, verified that this medicament is to the control efficiency of rice leaf roller, rice fulgorid, effective dose and the safety to paddy rice.Trial crops is paddy rice, controlling object rice leaf roller (Cnaphalocrocis medinalis), brown planthopper (Nilaparvata lugens).Test medicine and dosage are: 40% 6000 times, 7000 times, 8000 times of cycloxaprid Rynaxypyr water dispersible granules, 40% 5000 times of cycloxaprid fipronil bisamide suspension agents, 6000 times, 7000 times, 10% 1000 times of cycloxaprid suspending agents, 20% 3000 times of Rynaxypyr suspending agents, 20% 2000 times of fipronil bisamide water dispersible granules.The cultivation condition of each community, water and fertilizer management uniformity.By amount of liquid medicine, be 45kg/667 ㎡, adopt manual sprayer evenly to spray, require each community rice leaf positive and negative even medicine.Separately establish blank, every processing repeats for 4 times, every community area 50 ㎡, and Gong40Ge community, random district group is arranged.Investigation radix before medicine, 3,7,14 days investigation preventive effects after rice leaf roller medicine, after rice fulgorid medicine, 1,7,14 day investigation preventive effect is observed paddy growth situation simultaneously, and visual test medicament has or not poisoning to produce to paddy rice.
Investigation statistics method
Rice leaf roller: take parallel great-jump-forward random sampling, 25 clumps of rice are looked in the sampling of 5 of every communities altogether, statistics leaf roll rate, with check plot leaf roll rate comparison, calculates relative control effect, investigates simultaneously and in leaf roll, has worm rate.
The total number of sheets * 100 of leaf roll rate (%)=investigation leaf roll number/investigate
Leaf roll rate * 100 after control efficiency (%)=(after blank district medicine after leaf roll rate-chemicals treatment district medicine leaf roll rate)/blank district medicine
Rice fulgorid: take the random sampling of balance-jump formula, every community 10 points, 2 clumps every (totally 20 clumps), record rice fulgorid (brown planthopper) borer population by basin bat method, by the borer population calculation correction preventive effect before every clump of medicine, after medicine.
Control efficiency (%)=[1-(borer population after the front borer population * treatment region medicine of check plot medicine)/(the front borer population of borer population * treatment region medicine after the medicine of check plot)] * 100.
Result of the test shows, 40% 6000 times, 7000 times, 8000 times of cycloxaprid Rynaxypyr water dispersible granules, 40% 5000 times of cycloxaprid fipronil bisamide suspension agents, 6000 times, 7000 times have more significant control efficiency to paddy rice rice leaf roller, brown planthopper, are obviously better than the control efficiency (table 6) of 1000 times of 10% cycloxaprid suspending agents, 3000 times of 20% Rynaxypyr suspending agents, 2000 times of 20% fipronil bisamide water dispersible granules.
Security survey, duration of test is observed, and all reagent agents, to paddy growth safety, occur without poisoning phenomenon.
Result of the test shows, after cycloxaprid and Rynaxypyr, fipronil bisamide are mixed, obviously improved the control efficiency of rice leaf roller, rice fulgorid and lasting period, when these two kinds of insects occur simultaneously, a dispenser reaches double and controls, reduced dosage, reduced medication number of times and drug cost, to paddy growth safety.
Biological Examples 2: control cotton cotton bollworm, cotten aphid field trial
Inventor has made formulation examples 12(42% cycloxaprid bromine cyanogen insect amide suspending agent in Weinan city Linwei district, Shaanxi Province in July, 2011), FORMULATION EXAMPLE 5(60% cycloxaprid thiophene insect amide water dispersible granules) control cotton cotton bollworm, cotten aphid field control effectiveness test, test is with reference to < < field control effectiveness test criterion () GB/T 17980.5-2000 insecticide control cotton bollworm > > and < < pesticide field efficacy medicine test criterion (two) GB/T 17980.75-2004 insecticide control cotton aphid > >.Trial crops is cotton, and controlling object is cotton cotton bollworm, cotten aphid.Test Cotton Fields soil is clay, middle fertility, the cultivation condition of each community, water and fertilizer management uniformity.Two kinds of subjects all occur heavier.Dispenser on July 23, is 60kg/667 ㎡ by amount of liquid medicine, adopts manual sprayer evenly to spray, require each community cotton leaf positive and negative, limit point, bud even medicine.Test medicine and dosage refer to table 7.Separately establish blank, every processing repeats for 4 times, every community area 50 ㎡, and Gong40Ge community, random district group is arranged.
Cotton bollworm investigation method: the mediant row random sampling of every community is listed and fixed 5 points, fix the cotton plant that 5 strains have bollworm eggs and larva at every, totally 25 strains, before medicine, record larva number and ovum number, the preventive effect of investigation investigation in 3,7 days to larva after medicine, after medicine, 14 days killed situations of investigation cotton buds and bolls are calculated preventive effect effect.
Cotten aphid investigation method: 5 samplings of diagonal, fix 4 strains at every, every strain is 3 of upper, middle and lower leaf fixedly, fixes altogether 60 leaves of investigation 20 strain, investigation records aphid number alive.Before medicine, investigate insect population radix, within after medicine 1,3,7 day, respectively investigate the remaining aphid number of 1 community, according to the residual worm amount calculation correction preventive effect of each day after insect population cardinal sum medicine before medicine.
During each investigation drug effect, observe the impact of each treatment region on cotton leaf, bud and other insect simultaneously.
Result of the test shows, 42% 4500 times, 5000 times, 5500 times of cycloxaprid bromine cyanogen insect amide suspending agents, 60% 6500 times, 7000 times, 7500 times of cycloxaprid thiophene insect amide water dispersible granules have more significant control efficiency to cotton cotton bollworm, cotten aphid, are obviously better than the control efficiency (table 7) of 1000 times of 10% cycloxaprid suspending agents, 2000 times of 20% bromine cyanogen insect amide suspending agents, 2000 times of 20% thiophene insect amide water dispersible granules.
In test, also find, each test of 42% cycloxaprid bromine cyanogen insect amide suspending agent, 60% cycloxaprid thiophene insect amide water dispersible granules, 10% cycloxaprid suspending agent is processed 3 world preventive effects after mirid pentatomid medicine also more than 80%, and 20% bromine cyanogen insect amide suspending agent, 20% thiophene insect amide water dispersible granules are very poor to mirid pentatomid preventive effect.
All test medicines are all very poor to cotton red spider preventive effect.
Security survey, duration of test is observed, and all reagent agents, to cotton growth safety, occur without poisoning phenomenon.
Result of the test shows, after cycloxaprid and bromine cyanogen insect amide, thiophene insect amide are mixed, obviously improved the control efficiency to cotton bollworm, cotten aphid, when these two kinds of insects occur simultaneously, a dispenser reaches double to be controlled, and the double Cotton plant bug of controlling, has reduced dosage simultaneously, medication number of times and drug cost have been reduced, to cotton growth safety.
From above embodiment, the Rynaxypyr of the first active component cycloxaprid and the second active component, bromine cyanogen insect amide, fipronil bisamide, the combination of thiophene insect amide is composite, can be made into water dispersible granules, wetting powder, suspending agent formulation, to rice leaf roller, brown plant-hopper, Wheat-cotton aphid, cotton bollworm, vegetables beet armyworm has significant control efficiency, dosage is few, control efficiency is high, the double advantage such as control, saved drug cost, reduce medication number of times and dosage, and good to crop safety, therefore on producing, have wide practical use.
In sum, composition of the present invention is to adopt two kinds of active component compound schemes, its activity and insecticidal effect are not the simple superposition of each composition activity, compare with existing unitary agent, except having significant insecticidal effect, and have significant synergistic effect, preparation less residue, pollution-free to crop, safety is good, meets the security requirement of pesticidal preparations.
Claims (8)
1. containing a Pesticidal combination for cycloxaprid, it is characterized in that its active component is cycloxaprid and Rynaxypyr,
The weight ratio of cycloxaprid and Rynaxypyr is 1:20～20:1.
2. according to claim 1 containing the Pesticidal combination of cycloxaprid, it is characterized in that: the weight ratio of cycloxaprid and Rynaxypyr is 1:15～15:1.
3. according to claim 2 containing the Pesticidal combination of cycloxaprid, it is characterized in that: the weight ratio of cycloxaprid and Rynaxypyr is 1:10～10:1.
4. according to claim 3 containing the Pesticidal combination of cycloxaprid, it is characterized in that: the weight ratio of cycloxaprid and Rynaxypyr is 1:5～5:1.
5. according to claim 1 containing the Pesticidal combination of cycloxaprid, it is characterized in that: the content sum of cycloxaprid and Rynaxypyr is described composition total weight 3%～80%.
6. according to claim 5 containing the Pesticidal combination of cycloxaprid, it is characterized in that: cycloxaprid and Rynaxypyr content sum are described composition total weight 5%～70%.
7. according to claim 1 containing the Pesticidal combination of cycloxaprid, it is characterized in that: described composition is water dispersible granules, wetting powder, suspending agent.
Described in claim 1 containing the Pesticidal combination of cycloxaprid the purposes in control paddy rice rice leaf roller, brown plant-hopper, wheat aphid, cotton aphid, cotton cotton bollworm, vegetables beet armyworm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210139997.XA CN102657189B (en) | 2012-05-08 | 2012-05-08 | Pesticide composition containing cycloxaprid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210139997.XA CN102657189B (en) | 2012-05-08 | 2012-05-08 | Pesticide composition containing cycloxaprid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102657189A CN102657189A (en) | 2012-09-12 |
| CN102657189B true CN102657189B (en) | 2014-04-30 |
Family
ID=46766876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210139997.XA Active CN102657189B (en) | 2012-05-08 | 2012-05-08 | Pesticide composition containing cycloxaprid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102657189B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104872151A (en) * | 2014-02-27 | 2015-09-02 | 上海生农生化制品有限公司 | Cycloxaprid and amide insecticide composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1631887A (en) * | 2004-11-23 | 2005-06-29 | 华东理工大学 | Nitryl methylene derivatives and uses thereof |
| CN101747320A (en) * | 2008-12-19 | 2010-06-23 | 华东理工大学 | Dialdehyde-built disinsection activity-having nitrogen or oxygen-containing heterocyclic compound and preparation method |
| CN102093389A (en) * | 2009-12-09 | 2011-06-15 | 华东理工大学 | Duplex and oxygen bridge heterlcyclic ring anabasine compound and preparation method thereof |
-
2012
- 2012-05-08 CN CN201210139997.XA patent/CN102657189B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1631887A (en) * | 2004-11-23 | 2005-06-29 | 华东理工大学 | Nitryl methylene derivatives and uses thereof |
| CN101747320A (en) * | 2008-12-19 | 2010-06-23 | 华东理工大学 | Dialdehyde-built disinsection activity-having nitrogen or oxygen-containing heterocyclic compound and preparation method |
| CN102093389A (en) * | 2009-12-09 | 2011-06-15 | 华东理工大学 | Duplex and oxygen bridge heterlcyclic ring anabasine compound and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid:Design, Synthesis, Crystal Structure,and Insecticidal Activities;XUSHENG SHAO,et al;《J. Agric. Food Chem》;20091112;第58卷(第5期);第2696-2702页 * |
| XUSHENG SHAO,et al.Divalent and Oxabridged Neonicotinoids Constructed by Dialdehydes and Nitromethylene Analogues of Imidacloprid:Design, Synthesis, Crystal Structure,and Insecticidal Activities.《J. Agric. Food Chem》.2009,第58卷(第5期),第2696-2702页. |
| 冯晓慧，等."几类药剂对大螟的室内毒力测定及田间防效评价".《南京农业大学学报》.2012,第34卷(第5期),第67-72页. |
| 冯晓慧,等."几类药剂对大螟的室内毒力测定及田间防效评价".《南京农业大学学报》.2012,第34卷(第5期),第67-72页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102657189A (en) | 2012-09-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102771510B (en) | Insecticidal composition containing fosthiazate | |
| CN102487952B (en) | Insecticidal composition containing cycloxaprid and biological insecticide | |
| CN101843251B (en) | Insecticidal compound containing methoxyfenozide and metaflumizone | |
| CN104642348A (en) | Insecticide bactericidal composition containing thifluzamide | |
| CN103271073B (en) | Insecticidal composition containing epoxy worm moiety and buprofezin | |
| CN103271074B (en) | Insecticide composition containing cycolxylidin and pymetrozine | |
| CN102805102B (en) | Disinsection combination containing fosthiazate and ryanodine receptor inhibitor insecticide | |
| CN102599169A (en) | Tolfenpyrad-containing insecticidal composition | |
| CN103283770B (en) | Insecticidal composition containing cycolxylidin and metaflumizone | |
| CN103262848B (en) | Insecticidal composition containing cycloxaprid and biological insecticide | |
| CN103125496A (en) | Novel insecticide composition compounding pymetrozine | |
| CN102696603B (en) | Insecticidal composition containing spinetoram | |
| CN102657189B (en) | Pesticide composition containing cycloxaprid | |
| CN102210320A (en) | Sulfoxaflor-containing insecticidal composition | |
| CN109221230A (en) | A kind of insecticide composition containing double third ring worm esters and imidaclothiz | |
| CN104814031B (en) | A kind of Pesticidal combination containing butene-fipronil and clothianidin | |
| CN103125514A (en) | Wheat paddock weeding composition containing sulfosulfuron and flucarbazone | |
| CN103444761B (en) | Cycolxylidin-containing pesticidal composition | |
| CN103891749A (en) | Insecticidal combination containing sulfoxaflore and metaflumizone | |
| CN104982443A (en) | Weeding composition with oxaziclomefone and mefenacet | |
| CN102771512B (en) | Insecticidal composition containing fosthiazate and pyridaben | |
| CN108124893A (en) | A kind of ternary weeding composition containing diflufenican | |
| CN102326583B (en) | Insecticidal composition containing epoxy insect pyridine and organic phosphorus insecticide | |
| CN102771492B (en) | Herbicide composition containing sulfosulfuron and clodinafop-propargyl | |
| CN104957158A (en) | Weeding combination containing oxaziclomefone and benthiocarb |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |