CN102958925B - 吡唑衍生物钙释放激活钙通道调节剂及非小细胞肺癌的治疗方法 - Google Patents
吡唑衍生物钙释放激活钙通道调节剂及非小细胞肺癌的治疗方法 Download PDFInfo
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- CN102958925B CN102958925B CN201080055388.5A CN201080055388A CN102958925B CN 102958925 B CN102958925 B CN 102958925B CN 201080055388 A CN201080055388 A CN 201080055388A CN 102958925 B CN102958925 B CN 102958925B
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| BR112017007218B1 (pt) * | 2014-10-08 | 2023-10-10 | Redx Pharma Plc | Derivados de n-piridil acetamida como inibidores da via de sinalização de wnt, formulações farmacêuticas compreendendo os mesmos e seus usos |
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| TWI771269B (zh) * | 2015-02-27 | 2022-07-21 | 美商鈣系醫藥公司 | 胰腺炎治療 |
| HUE048902T2 (hu) * | 2015-08-03 | 2020-08-28 | Glenmark Pharmaceuticals Sa | Új ROR gamma modulátor vegyületek |
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| ITUA20164199A1 (it) | 2016-06-08 | 2017-12-08 | Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro | Modulatori di soce compisizioni e relativi usi |
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- 2010-10-07 DK DK10776149.6T patent/DK2509974T3/en active
- 2010-10-07 LT LTEP10776149.6T patent/LT2509974T/lt unknown
- 2010-10-07 WO PCT/IB2010/002539 patent/WO2011042798A1/en not_active Ceased
- 2010-10-07 HR HRP20181014TT patent/HRP20181014T1/hr unknown
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- 2010-10-07 SI SI201031711T patent/SI2509974T1/en unknown
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- 2010-10-07 EA EA201290139A patent/EA025302B8/ru unknown
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- 2010-10-07 CN CN201510114126.6A patent/CN104788430B/zh not_active Expired - Fee Related
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2015
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- 2015-08-14 JP JP2015160031A patent/JP6266568B2/ja not_active Expired - Fee Related
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2017
- 2017-12-20 JP JP2017243778A patent/JP2018080176A/ja active Pending
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2018
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6348480B1 (en) * | 1997-10-13 | 2002-02-19 | Yamanouchi Pharmaceutical Co., Ltd. | Pharmaceutical compound comprising a pyrazole derivative and methods of using the same for the treatment of calcium release-activated calcium channel associated diseases |
| EP1875925A1 (en) * | 2005-04-22 | 2008-01-09 | Astellas Pharma Inc. | Preventive or remedy for bowel disease |
| WO2009076454A2 (en) * | 2007-12-12 | 2009-06-18 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
Also Published As
| Publication number | Publication date |
|---|---|
| EA201290139A1 (ru) | 2012-11-30 |
| CA2784277A1 (en) | 2011-04-14 |
| US10174034B2 (en) | 2019-01-08 |
| CN104788430B (zh) | 2019-10-22 |
| CN110627724A (zh) | 2019-12-31 |
| TR201809711T4 (tr) | 2018-07-23 |
| HUE039261T2 (hu) | 2018-12-28 |
| LT2509974T (lt) | 2018-07-10 |
| US8993612B2 (en) | 2015-03-31 |
| ES2676317T3 (es) | 2018-07-18 |
| SMT201800361T1 (it) | 2018-09-13 |
| SI2509974T1 (en) | 2018-08-31 |
| JP5909312B2 (ja) | 2016-04-26 |
| JP2016028037A (ja) | 2016-02-25 |
| US20190248791A1 (en) | 2019-08-15 |
| JP2018080176A (ja) | 2018-05-24 |
| WO2011042798A1 (en) | 2011-04-14 |
| US20110112058A1 (en) | 2011-05-12 |
| EA025302B8 (ru) | 2017-07-31 |
| EP2509974A1 (en) | 2012-10-17 |
| PL2509974T3 (pl) | 2018-11-30 |
| EA025302B1 (ru) | 2016-12-30 |
| RS57441B1 (sr) | 2018-09-28 |
| JP6266568B2 (ja) | 2018-01-24 |
| DK2509974T3 (en) | 2018-07-30 |
| CA2784277C (en) | 2019-09-24 |
| US20150291588A1 (en) | 2015-10-15 |
| HRP20181014T1 (hr) | 2018-08-24 |
| EP2509974B1 (en) | 2018-04-11 |
| CN102958925A (zh) | 2013-03-06 |
| CN104788430A (zh) | 2015-07-22 |
| JP2013507351A (ja) | 2013-03-04 |
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