CN102883716B - 改善伴有学习/记忆障碍和运动障碍等的中枢神经变性疾病的干燥植物组织和植物组织提取物以及含有它们的药品和食品 - Google Patents

改善伴有学习/记忆障碍和运动障碍等的中枢神经变性疾病的干燥植物组织和植物组织提取物以及含有它们的药品和食品 Download PDF

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CN102883716B
CN102883716B CN201180011122.5A CN201180011122A CN102883716B CN 102883716 B CN102883716 B CN 102883716B CN 201180011122 A CN201180011122 A CN 201180011122A CN 102883716 B CN102883716 B CN 102883716B
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plant tissue
radix
extract
nobiletin
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CN102883716A (zh
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大泉康
山国彻
川畑伊知郎
吉田雅昭
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Kotaro Pharmaceutical Co ltd
Tohoku University NUC
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Kotaro Pharmaceutical Co ltd
Tohoku University NUC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Psychology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201180011122.5A 2010-02-26 2011-02-25 改善伴有学习/记忆障碍和运动障碍等的中枢神经变性疾病的干燥植物组织和植物组织提取物以及含有它们的药品和食品 Active CN102883716B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2010042819 2010-02-26
JP2010-042819 2010-02-26
JP2010-126717 2010-06-02
JP2010126717 2010-06-02
JP2010270578 2010-12-03
JP2010-270578 2010-12-03
PCT/JP2011/054358 WO2011105568A1 (ja) 2010-02-26 2011-02-25 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品

Publications (2)

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CN102883716A CN102883716A (zh) 2013-01-16
CN102883716B true CN102883716B (zh) 2014-05-07

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CN201180011122.5A Active CN102883716B (zh) 2010-02-26 2011-02-25 改善伴有学习/记忆障碍和运动障碍等的中枢神经变性疾病的干燥植物组织和植物组织提取物以及含有它们的药品和食品

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JP (2) JP5503726B2 (https=)
CN (1) CN102883716B (https=)
WO (1) WO2011105568A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013191236A1 (ja) * 2012-06-21 2013-12-27 小太郎漢方製薬株式会社 中枢神経変性疾患の改善および/または治療用組成物
CN103479743B (zh) * 2013-01-28 2015-07-08 钱昌美 治疗老年痴呆的药物组合物及其制备方法
JP6179891B2 (ja) * 2013-05-29 2017-08-16 要 有持 生産方法、加工方法、加工品及び茶
JP2015053939A (ja) * 2013-09-10 2015-03-23 久子 松野 みかんの果皮の加工食品
JP5958658B2 (ja) * 2014-06-26 2016-08-02 日本ゼオン株式会社 培養細胞内のerkまたはaktのリン酸化亢進方法、細胞の培養方法、およびリン酸化亢進剤
JP2016056149A (ja) * 2014-09-11 2016-04-21 日油株式会社 皮膚化粧料
WO2016075960A1 (ja) * 2014-11-12 2016-05-19 株式会社沖縄リサーチセンター 排尿障害を予防又は改善させる医薬組成物、排尿障害関連受容体に関する拮抗剤又はその医薬組成物又は拮抗剤を用いた排尿障害を予防又は改善させる方法
JP6238089B1 (ja) * 2016-06-01 2017-11-29 株式会社三協ホールディングス 医薬組成物および食品
JP6898628B2 (ja) * 2016-06-15 2021-07-07 国立大学法人広島大学 神経変性疾患治療剤
CN107648349A (zh) * 2017-10-30 2018-02-02 江西中医药大学 代代花在制备改善睡眠障碍或改善记忆力减退或治疗阿尔茨海默病药物或保健食品中的应用
WO2019102602A1 (ja) * 2017-11-27 2019-05-31 康 大泉 スクリーニング方法
KR101894491B1 (ko) * 2018-04-30 2018-09-04 주식회사 뉴트라팜텍 지각 초임계 추출물을 유효성분으로 함유하는 기억력 또는 인지 기능 개선용 조성물
CN112402409A (zh) * 2020-12-11 2021-02-26 江汉大学 橘皮素在制备抑制β分泌酶活性药物中的应用
CN115886258B (zh) * 2022-12-30 2024-07-05 上海交大昂立股份有限公司 一种改善生理性记忆力衰减的复合益生菌组合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053152A1 (en) * 2001-01-08 2002-07-11 Imperial College Of Science, Technology & Medicine Composition containing flavonoids for treatment brain disorders
JP2008127325A (ja) * 2006-11-20 2008-06-05 Tokyoto Koreisha Kenkyu Fukushi Shinko Zaidan リン酸化mbp産生促進剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002053152A1 (en) * 2001-01-08 2002-07-11 Imperial College Of Science, Technology & Medicine Composition containing flavonoids for treatment brain disorders
JP2008127325A (ja) * 2006-11-20 2008-06-05 Tokyoto Koreisha Kenkyu Fukushi Shinko Zaidan リン酸化mbp産生促進剤

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Publication number Publication date
HK1178792A1 (en) 2013-09-19
CN102883716A (zh) 2013-01-16
JP5503726B2 (ja) 2014-05-28
JP5906267B2 (ja) 2016-04-20
JPWO2011105568A1 (ja) 2013-06-20
JP2014111664A (ja) 2014-06-19
WO2011105568A1 (ja) 2011-09-01

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