CN102791661B - 二氟环丙烷化合物的制造方法 - Google Patents

二氟环丙烷化合物的制造方法 Download PDF

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Publication number
CN102791661B
CN102791661B CN201080060908.1A CN201080060908A CN102791661B CN 102791661 B CN102791661 B CN 102791661B CN 201080060908 A CN201080060908 A CN 201080060908A CN 102791661 B CN102791661 B CN 102791661B
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China
Prior art keywords
compound
difluoro
ring
derivatives
skeleton
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Expired - Fee Related
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CN201080060908.1A
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English (en)
Chinese (zh)
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CN102791661A (zh
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网井秀树
大城幸纯
森本佳道
松浦诚
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Central Glass Co Ltd
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Central Glass Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • C07F7/1872Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/26Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/272Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/227Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/233Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C49/235Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/567Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/28Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/293Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/20All rings being cycloaliphatic the ring system containing seven carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201080060908.1A 2010-01-08 2010-10-26 二氟环丙烷化合物的制造方法 Expired - Fee Related CN102791661B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010-003201 2010-01-08
JP2010003201A JP5504898B2 (ja) 2010-01-08 2010-01-08 ジフルオロシクロプロパン化合物の製造方法
PCT/JP2010/068932 WO2011083612A1 (ja) 2010-01-08 2010-10-26 ジフルオロシクロプロパン化合物の製造方法

Publications (2)

Publication Number Publication Date
CN102791661A CN102791661A (zh) 2012-11-21
CN102791661B true CN102791661B (zh) 2016-02-17

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CN201080060908.1A Expired - Fee Related CN102791661B (zh) 2010-01-08 2010-10-26 二氟环丙烷化合物的制造方法

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US (1) US8729320B2 (https=)
EP (1) EP2522648B1 (https=)
JP (1) JP5504898B2 (https=)
CN (1) CN102791661B (https=)
WO (1) WO2011083612A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5504898B2 (ja) * 2010-01-08 2014-05-28 セントラル硝子株式会社 ジフルオロシクロプロパン化合物の製造方法
JP6133741B2 (ja) * 2013-09-26 2017-05-24 国立大学法人東京工業大学 ジフルオロシクロプロパン化合物類の製造方法
CN116514897B (zh) * 2023-05-09 2024-03-29 暨南大学 环丙烷或者环丙烯类化合物及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201881A (en) * 1979-03-28 1980-05-06 Wisconsin Alumni Research Foundation 24,24-Difluoro-1α,25-dihydroxycholecalciferol
CN1033271A (zh) * 1987-11-27 1989-06-07 先灵公司 2,2-二氟环丙基乙烷衍生物的制备方法及其作为杀虫剂的用途
CN1270165A (zh) * 1999-02-04 2000-10-18 Ss制药株式会社 二氟苯乙酮衍生物的制备方法
US20090318408A1 (en) * 2008-06-18 2009-12-24 Jianping Cai Halo-substituted pyrimidodiazepines

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3825606A (en) 1972-06-02 1974-07-23 Grace W R & Co Fluorocyclopropanes as inhalation anesthetics
IT1050705B (it) * 1972-06-02 1981-03-20 Grace W R & Co Procedimento per preparare aloge nociclopropani
US3903181A (en) 1972-06-02 1975-09-02 Grace W R & Co 1-Bromo-2,2-difluorocyclopropane
US3906111A (en) * 1974-03-15 1975-09-16 Grace W R & Co Halogenated methylcyclopropyl ethers for inducing a state of anesthesia
US3928468A (en) 1974-03-15 1975-12-23 Grace W R & Co Halogenated methylcyclopropyl ethers
JPH0578272A (ja) * 1991-06-14 1993-03-30 Dainippon Ink & Chem Inc 光学活性ジフルオロシクロプロパン誘導体、それを含有する液晶組成物及び液晶表示素子
US6291409B1 (en) 1998-07-02 2001-09-18 Cargill, Inc. Process for modifying unsaturated triacylglycerol oils; Resulting products and uses thereof
US6051539A (en) 1998-07-02 2000-04-18 Cargill, Inc. Process for modifying unsaturated triacylglycerol oils resulting products and uses thereof
JP2001213830A (ja) 2000-01-27 2001-08-07 Daicel Chem Ind Ltd ジフルオロシクロプロパン誘導体
JP4419385B2 (ja) * 2002-12-05 2010-02-24 三菱瓦斯化学株式会社 含フッ素脂環式化合物の製造方法
JP5504898B2 (ja) * 2010-01-08 2014-05-28 セントラル硝子株式会社 ジフルオロシクロプロパン化合物の製造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201881A (en) * 1979-03-28 1980-05-06 Wisconsin Alumni Research Foundation 24,24-Difluoro-1α,25-dihydroxycholecalciferol
CN1033271A (zh) * 1987-11-27 1989-06-07 先灵公司 2,2-二氟环丙基乙烷衍生物的制备方法及其作为杀虫剂的用途
CN1270165A (zh) * 1999-02-04 2000-10-18 Ss制药株式会社 二氟苯乙酮衍生物的制备方法
US20090318408A1 (en) * 2008-06-18 2009-12-24 Jianping Cai Halo-substituted pyrimidodiazepines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemoselective and stereoselective synthesis of gem-difluoro-β-aminoesters or gem-difluoro-β-lactams from ethylbromodifluoroacetate and imines during Reformatsky reaction;Nicolas Boyer et al;《Tetrahedron》;20071210;第63卷(第50期);第12352-12366页 *

Also Published As

Publication number Publication date
US20120277458A1 (en) 2012-11-01
EP2522648B1 (en) 2017-05-17
EP2522648A4 (en) 2013-05-29
CN102791661A (zh) 2012-11-21
US8729320B2 (en) 2014-05-20
JP2011140474A (ja) 2011-07-21
JP5504898B2 (ja) 2014-05-28
WO2011083612A1 (ja) 2011-07-14
EP2522648A1 (en) 2012-11-14

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