CN102791661B - 二氟环丙烷化合物的制造方法 - Google Patents
二氟环丙烷化合物的制造方法 Download PDFInfo
- Publication number
- CN102791661B CN102791661B CN201080060908.1A CN201080060908A CN102791661B CN 102791661 B CN102791661 B CN 102791661B CN 201080060908 A CN201080060908 A CN 201080060908A CN 102791661 B CN102791661 B CN 102791661B
- Authority
- CN
- China
- Prior art keywords
- compound
- difluoro
- ring
- derivatives
- skeleton
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/272—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
- C07C49/233—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C49/235—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
- C07C49/567—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
- C07C67/293—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/20—All rings being cycloaliphatic the ring system containing seven carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010-003201 | 2010-01-08 | ||
| JP2010003201A JP5504898B2 (ja) | 2010-01-08 | 2010-01-08 | ジフルオロシクロプロパン化合物の製造方法 |
| PCT/JP2010/068932 WO2011083612A1 (ja) | 2010-01-08 | 2010-10-26 | ジフルオロシクロプロパン化合物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102791661A CN102791661A (zh) | 2012-11-21 |
| CN102791661B true CN102791661B (zh) | 2016-02-17 |
Family
ID=44305352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080060908.1A Expired - Fee Related CN102791661B (zh) | 2010-01-08 | 2010-10-26 | 二氟环丙烷化合物的制造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8729320B2 (https=) |
| EP (1) | EP2522648B1 (https=) |
| JP (1) | JP5504898B2 (https=) |
| CN (1) | CN102791661B (https=) |
| WO (1) | WO2011083612A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5504898B2 (ja) * | 2010-01-08 | 2014-05-28 | セントラル硝子株式会社 | ジフルオロシクロプロパン化合物の製造方法 |
| JP6133741B2 (ja) * | 2013-09-26 | 2017-05-24 | 国立大学法人東京工業大学 | ジフルオロシクロプロパン化合物類の製造方法 |
| CN116514897B (zh) * | 2023-05-09 | 2024-03-29 | 暨南大学 | 环丙烷或者环丙烯类化合物及其应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4201881A (en) * | 1979-03-28 | 1980-05-06 | Wisconsin Alumni Research Foundation | 24,24-Difluoro-1α,25-dihydroxycholecalciferol |
| CN1033271A (zh) * | 1987-11-27 | 1989-06-07 | 先灵公司 | 2,2-二氟环丙基乙烷衍生物的制备方法及其作为杀虫剂的用途 |
| CN1270165A (zh) * | 1999-02-04 | 2000-10-18 | Ss制药株式会社 | 二氟苯乙酮衍生物的制备方法 |
| US20090318408A1 (en) * | 2008-06-18 | 2009-12-24 | Jianping Cai | Halo-substituted pyrimidodiazepines |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3825606A (en) | 1972-06-02 | 1974-07-23 | Grace W R & Co | Fluorocyclopropanes as inhalation anesthetics |
| IT1050705B (it) * | 1972-06-02 | 1981-03-20 | Grace W R & Co | Procedimento per preparare aloge nociclopropani |
| US3903181A (en) | 1972-06-02 | 1975-09-02 | Grace W R & Co | 1-Bromo-2,2-difluorocyclopropane |
| US3906111A (en) * | 1974-03-15 | 1975-09-16 | Grace W R & Co | Halogenated methylcyclopropyl ethers for inducing a state of anesthesia |
| US3928468A (en) | 1974-03-15 | 1975-12-23 | Grace W R & Co | Halogenated methylcyclopropyl ethers |
| JPH0578272A (ja) * | 1991-06-14 | 1993-03-30 | Dainippon Ink & Chem Inc | 光学活性ジフルオロシクロプロパン誘導体、それを含有する液晶組成物及び液晶表示素子 |
| US6291409B1 (en) | 1998-07-02 | 2001-09-18 | Cargill, Inc. | Process for modifying unsaturated triacylglycerol oils; Resulting products and uses thereof |
| US6051539A (en) | 1998-07-02 | 2000-04-18 | Cargill, Inc. | Process for modifying unsaturated triacylglycerol oils resulting products and uses thereof |
| JP2001213830A (ja) | 2000-01-27 | 2001-08-07 | Daicel Chem Ind Ltd | ジフルオロシクロプロパン誘導体 |
| JP4419385B2 (ja) * | 2002-12-05 | 2010-02-24 | 三菱瓦斯化学株式会社 | 含フッ素脂環式化合物の製造方法 |
| JP5504898B2 (ja) * | 2010-01-08 | 2014-05-28 | セントラル硝子株式会社 | ジフルオロシクロプロパン化合物の製造方法 |
-
2010
- 2010-01-08 JP JP2010003201A patent/JP5504898B2/ja not_active Expired - Fee Related
- 2010-10-26 US US13/520,691 patent/US8729320B2/en not_active Expired - Fee Related
- 2010-10-26 WO PCT/JP2010/068932 patent/WO2011083612A1/ja not_active Ceased
- 2010-10-26 CN CN201080060908.1A patent/CN102791661B/zh not_active Expired - Fee Related
- 2010-10-26 EP EP10842127.2A patent/EP2522648B1/en not_active Not-in-force
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4201881A (en) * | 1979-03-28 | 1980-05-06 | Wisconsin Alumni Research Foundation | 24,24-Difluoro-1α,25-dihydroxycholecalciferol |
| CN1033271A (zh) * | 1987-11-27 | 1989-06-07 | 先灵公司 | 2,2-二氟环丙基乙烷衍生物的制备方法及其作为杀虫剂的用途 |
| CN1270165A (zh) * | 1999-02-04 | 2000-10-18 | Ss制药株式会社 | 二氟苯乙酮衍生物的制备方法 |
| US20090318408A1 (en) * | 2008-06-18 | 2009-12-24 | Jianping Cai | Halo-substituted pyrimidodiazepines |
Non-Patent Citations (1)
| Title |
|---|
| Chemoselective and stereoselective synthesis of gem-difluoro-β-aminoesters or gem-difluoro-β-lactams from ethylbromodifluoroacetate and imines during Reformatsky reaction;Nicolas Boyer et al;《Tetrahedron》;20071210;第63卷(第50期);第12352-12366页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20120277458A1 (en) | 2012-11-01 |
| EP2522648B1 (en) | 2017-05-17 |
| EP2522648A4 (en) | 2013-05-29 |
| CN102791661A (zh) | 2012-11-21 |
| US8729320B2 (en) | 2014-05-20 |
| JP2011140474A (ja) | 2011-07-21 |
| JP5504898B2 (ja) | 2014-05-28 |
| WO2011083612A1 (ja) | 2011-07-14 |
| EP2522648A1 (en) | 2012-11-14 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160217 Termination date: 20191026 |
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| CF01 | Termination of patent right due to non-payment of annual fee |