CN102770764B - 对给定靶标具有亲和力的人脂质运载蛋白2(Lcn2,hNGAL)的突变蛋白 - Google Patents

对给定靶标具有亲和力的人脂质运载蛋白2(Lcn2,hNGAL)的突变蛋白 Download PDF

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CN102770764B
CN102770764B CN201080055370.5A CN201080055370A CN102770764B CN 102770764 B CN102770764 B CN 102770764B CN 201080055370 A CN201080055370 A CN 201080055370A CN 102770764 B CN102770764 B CN 102770764B
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mutein
sequence
amino acid
protein
lcn2
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CN102770764A (zh
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A·斯克拉
M·格鲍尔
D·欣兹
S·劳特
G·马钦内尔
M·胡尔斯迈尔
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Pieris Pharmaceuticals GmbH
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K2319/00—Fusion polypeptide
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CN201080055370.5A 2009-12-07 2010-12-07 对给定靶标具有亲和力的人脂质运载蛋白2(Lcn2,hNGAL)的突变蛋白 Active CN102770764B (zh)

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Application Number Priority Date Filing Date Title
US26709809P 2009-12-07 2009-12-07
US61/267,098 2009-12-07
PCT/EP2010/069028 WO2011069992A2 (en) 2009-12-07 2010-12-07 Muteins of human lipocalin 2 (lcn2, hngal) with affinity for a given target

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CN102770764A CN102770764A (zh) 2012-11-07
CN102770764B true CN102770764B (zh) 2016-04-20

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JP (5) JP5913120B2 (enExample)
KR (2) KR101974044B1 (enExample)
CN (1) CN102770764B (enExample)
AU (1) AU2010329995B2 (enExample)
BR (1) BR112012013662B1 (enExample)
CA (1) CA2779562C (enExample)
DK (2) DK2990798T3 (enExample)
RU (2) RU2707126C2 (enExample)
SG (1) SG10201408073XA (enExample)
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US20170114109A1 (en) 2017-04-27
JP2013512683A (ja) 2013-04-18
JP6346159B2 (ja) 2018-06-20
SG10201408073XA (en) 2015-01-29
JP2018148914A (ja) 2018-09-27
WO2011069992A2 (en) 2011-06-16
JP2022160410A (ja) 2022-10-19
RU2707126C2 (ru) 2019-11-22
EP2990798A1 (en) 2016-03-02
RU2015137158A3 (enExample) 2018-12-25
CA2779562C (en) 2019-12-31
JP2021006024A (ja) 2021-01-21
AU2010329995A1 (en) 2012-05-10
CA2779562A1 (en) 2011-06-16
EP2990798B1 (en) 2019-09-25
JP2016105709A (ja) 2016-06-16
US20130079286A1 (en) 2013-03-28
WO2011069992A3 (en) 2011-08-11
KR101974044B1 (ko) 2019-04-30
RU2012128586A (ru) 2014-01-20
DK2990798T3 (da) 2019-12-02
JP7482544B2 (ja) 2024-05-14
US9549968B2 (en) 2017-01-24
KR20180031081A (ko) 2018-03-27
US11827681B2 (en) 2023-11-28
JP5913120B2 (ja) 2016-05-11
RU2015137158A (ru) 2018-12-25
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