CN102753186B - 血管生成素样3表达的调节 - Google Patents
血管生成素样3表达的调节 Download PDFInfo
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- CN102753186B CN102753186B CN201180008657.7A CN201180008657A CN102753186B CN 102753186 B CN102753186 B CN 102753186B CN 201180008657 A CN201180008657 A CN 201180008657A CN 102753186 B CN102753186 B CN 102753186B
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610643333.5A CN106146591B (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
| CN202010636959.XA CN111700901A (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29360410P | 2010-01-08 | 2010-01-08 | |
| US61/293,604 | 2010-01-08 | ||
| PCT/US2011/020606 WO2011085271A2 (en) | 2010-01-08 | 2011-01-07 | Modulation of angiopoietin-like 3 expression |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610643333.5A Division CN106146591B (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
| CN202010636959.XA Division CN111700901A (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102753186A CN102753186A (zh) | 2012-10-24 |
| CN102753186B true CN102753186B (zh) | 2016-09-14 |
Family
ID=44306180
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180008657.7A Expired - Fee Related CN102753186B (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
| CN201610643333.5A Expired - Fee Related CN106146591B (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
| CN202010636959.XA Pending CN111700901A (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610643333.5A Expired - Fee Related CN106146591B (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
| CN202010636959.XA Pending CN111700901A (zh) | 2010-01-08 | 2011-01-07 | 血管生成素样3表达的调节 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US8653047B2 (enExample) |
| EP (2) | EP2521556B1 (enExample) |
| JP (4) | JP5822845B2 (enExample) |
| CN (3) | CN102753186B (enExample) |
| AU (1) | AU2011203986C1 (enExample) |
| CA (1) | CA2786071C (enExample) |
| DK (1) | DK2521556T3 (enExample) |
| ES (1) | ES2677969T3 (enExample) |
| WO (1) | WO2011085271A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11851655B2 (en) | 2013-05-01 | 2023-12-26 | Ionis Pharmaceuticals, Inc. | Compositions and methods for modulating apolipoprotein (a) expression |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102282155B (zh) | 2008-12-02 | 2017-06-09 | 日本波涛生命科学公司 | 磷原子修饰的核酸的合成方法 |
| RU2612521C2 (ru) | 2009-07-06 | 2017-03-09 | Онтории, Инк. | Новые пролекарства нуклеиновых кислот и способы их применения |
| CN102753186B (zh) * | 2010-01-08 | 2016-09-14 | Isis制药公司 | 血管生成素样3表达的调节 |
| JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
| AR087329A1 (es) | 2011-06-17 | 2014-03-19 | Regeneron Pharma | Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana |
| EP2723758B1 (en) | 2011-06-21 | 2018-06-20 | Alnylam Pharmaceuticals, Inc. | Angiopoietin-like 3 (angptl3) irna compostions and methods of use thereof |
| CN103796657B (zh) | 2011-07-19 | 2017-07-11 | 波涛生命科学有限公司 | 合成官能化核酸的方法 |
| WO2013033230A1 (en) | 2011-08-29 | 2013-03-07 | Isis Pharmaceuticals, Inc. | Oligomer-conjugate complexes and their use |
| HRP20191883T1 (hr) * | 2011-11-07 | 2019-12-27 | Ionis Pharmaceuticals, Inc. | Modulacija ekspresije tmprss6 |
| SI3366775T2 (sl) * | 2011-11-18 | 2025-12-31 | Alnylam Pharmaceuticals, Inc. | Modificirana sredstva RNAI |
| KR102213609B1 (ko) | 2012-07-13 | 2021-02-08 | 웨이브 라이프 사이언시스 리미티드 | 키랄 제어 |
| PL2872485T3 (pl) | 2012-07-13 | 2021-05-31 | Wave Life Sciences Ltd. | Asymetryczna grupa pomocnicza |
| CA2879066C (en) | 2012-07-13 | 2019-08-13 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant |
| CN104837996A (zh) | 2012-11-15 | 2015-08-12 | 罗氏创新中心哥本哈根有限公司 | 抗apob反义缀合物化合物 |
| AU2014211406B2 (en) | 2013-01-30 | 2019-07-18 | Roche Innovation Center Copenhagen A/S | LNA oligonucleotide carbohydrate conjugates |
| TW202246503A (zh) * | 2013-07-19 | 2022-12-01 | 美商百健Ma公司 | 用於調節τ蛋白表現之組合物 |
| PT3087183T (pt) * | 2013-12-24 | 2020-10-08 | Ionis Pharmaceuticals Inc | Modulação da expressão da proteína relacionada com angiopoietina 3 |
| US10322173B2 (en) | 2014-01-15 | 2019-06-18 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| JPWO2015108047A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| JPWO2015108048A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| BR112016016400A2 (pt) | 2014-01-16 | 2017-10-03 | Wave Life Sciences Ltd | Composições de oligonucleotídeos quiralmente controlados, seu uso, sua composição farmacêutica, e métodos |
| US9382540B2 (en) * | 2014-05-01 | 2016-07-05 | Isis Pharmaceuticals, Inc | Compositions and methods for modulating angiopoietin-like 3 expression |
| WO2015179693A1 (en) | 2014-05-22 | 2015-11-26 | Isis Pharmaceuticals, Inc. | Conjugated antisense compounds and their use |
| US20180245077A1 (en) * | 2015-03-20 | 2018-08-30 | Protiva Biotherapeutics, Inc. | Compositions and methods for treating hypertriglyceridemia |
| MX2017012426A (es) | 2015-04-03 | 2018-01-26 | Ionis Pharmaceuticals Inc | Composiciones y metodos para modular la expresion de tmprss6. |
| CN115927335A (zh) | 2015-04-13 | 2023-04-07 | 阿尔尼拉姆医药品有限公司 | 类血管生成素3(ANGPTL3)iRNA组合物及其使用方法 |
| PL4119569T3 (pl) | 2015-11-06 | 2024-11-18 | Ionis Pharmaceuticals, Inc. | Sprzężone związki antysensowne do zastosowania w terapii |
| HK1257929A1 (zh) * | 2015-11-06 | 2019-11-01 | Gemphire Therapeutics Inc. | 治疗混合性血脂异常 |
| KR20250078597A (ko) | 2015-11-06 | 2025-06-02 | 아이오니스 파마수티컬즈, 인코포레이티드 | 아포리포프로테인 (a) 발현 조정 |
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