CN102652176B - 茎部加速的等温核酸扩增技术 - Google Patents

茎部加速的等温核酸扩增技术 Download PDF

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Publication number
CN102652176B
CN102652176B CN201080035868.5A CN201080035868A CN102652176B CN 102652176 B CN102652176 B CN 102652176B CN 201080035868 A CN201080035868 A CN 201080035868A CN 102652176 B CN102652176 B CN 102652176B
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primer
fragment
stem
ring
sequence
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CN102652176A (zh
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劳伦斯·C·第希
盖伊·柯德乐
奥尔加·甘德尔曼
凯瑟·J·迈克滚
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Lumora Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
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  • Microbiology (AREA)
  • Molecular Biology (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201080035868.5A 2009-06-15 2010-06-15 茎部加速的等温核酸扩增技术 Active CN102652176B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0910302.9 2009-06-15
GBGB0910302.9A GB0910302D0 (en) 2009-06-15 2009-06-15 Nucleic acid amplification
PCT/GB2010/001169 WO2010146349A1 (en) 2009-06-15 2010-06-15 Stem accelerated isothermal nucleic acid amplification technology

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CN102652176A CN102652176A (zh) 2012-08-29
CN102652176B true CN102652176B (zh) 2016-09-28

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US (1) US9410190B2 (https=)
EP (1) EP2443253B1 (https=)
JP (2) JP5907864B2 (https=)
CN (1) CN102652176B (https=)
AU (1) AU2010261541B2 (https=)
CA (1) CA2765406C (https=)
ES (1) ES2589079T3 (https=)
GB (1) GB0910302D0 (https=)
WO (1) WO2010146349A1 (https=)
ZA (1) ZA201109493B (https=)

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US10450595B2 (en) 2013-03-15 2019-10-22 Theranos Ip Company, Llc Nucleic acid amplification
CN105452480B (zh) * 2013-08-09 2020-01-31 基因生物系统股份有限公司 经由剪刀状结构的dna扩增(dasl)
WO2015035260A1 (en) 2013-09-06 2015-03-12 Theranos, Inc. Systems and methods for detecting infectious diseases
CN103497947B (zh) * 2013-09-13 2015-08-12 浙江国际旅行卫生保健中心 一种体外新型快速环介导等温扩增方法、体外检测甲型h1n1流感病毒的试剂及方法
AU2014353462A1 (en) * 2013-11-22 2016-05-05 Theranos Ip Company, Llc Nucleic acid amplification
US11859246B2 (en) 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
CN104946737B (zh) 2013-12-11 2019-02-22 安可济控股有限公司 用于检测罕见序列变体的组合物和方法
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
US10716587B2 (en) 2014-06-13 2020-07-21 Surgis Medical Llc Surgical device with light
US11559801B2 (en) 2014-11-03 2023-01-24 Tangen Biosciences, Inc. Apparatus and method for cell, spore, or virus capture and disruption
ES2891085T3 (es) 2015-01-30 2022-01-26 Harvard College Obtención de imágenes sin microscopio
CN107208162B (zh) 2015-02-26 2020-12-29 株式会社日立高新技术 核酸分子的构建方法
US10260090B2 (en) 2015-07-16 2019-04-16 Arizona Board Of Regents On Behalf Of Arizona State University Accelerated isothermal amplification of DNA
AU2016334233B2 (en) 2015-10-09 2023-01-05 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
CN108699505A (zh) 2015-12-03 2018-10-23 安可济控股有限公司 用于形成连接产物的方法和组合物
CN116949140A (zh) 2016-02-17 2023-10-27 哈佛学院院长及董事 分子编程工具
CA3024630A1 (en) 2016-05-16 2017-11-23 Accuragen Holdings Limited Method of improved sequencing by strand identification
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
CN107488656B (zh) * 2016-06-13 2020-07-17 陆欣华 一种核酸等温自扩增方法
CA3033749C (en) 2016-08-15 2026-03-24 Accuragen Holdings Limited Compositions and methods for detecting rare sequence variants
EP3568492B1 (en) * 2017-01-10 2025-01-01 President and Fellows of Harvard College Multiplexed signal amplification
EP3724322A1 (en) 2017-12-14 2020-10-21 Medicinal Genomics Corporation Methods and kits for classifying cannabinoid production in cannabis plants
CN111630179B (zh) 2018-01-26 2024-07-19 哈佛学院院长及董事 邻近检测方法和组合物
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
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CN118621045A (zh) * 2024-08-14 2024-09-10 天健生物制药（天津）有限公司 基于lamp的鸟分枝杆菌检测的组合物和试剂盒
WO2026050948A1 (zh) * 2024-09-04 2026-03-12 深圳华大生命科学研究院 核酸文库的构建方法及应用

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Also Published As

Publication number Publication date
EP2443253A1 (en) 2012-04-25
ZA201109493B (en) 2015-07-29
JP6106732B2 (ja) 2017-04-05
JP2012529904A (ja) 2012-11-29
CA2765406A1 (en) 2010-12-23
JP5907864B2 (ja) 2016-04-26
AU2010261541B2 (en) 2016-03-10
EP2443253B1 (en) 2016-06-08
US20120157326A1 (en) 2012-06-21
CN102652176A (zh) 2012-08-29
US9410190B2 (en) 2016-08-09
AU2010261541A1 (en) 2012-02-02
WO2010146349A1 (en) 2010-12-23
GB0910302D0 (en) 2009-07-29
ES2589079T3 (es) 2016-11-10
CA2765406C (en) 2019-02-26
JP2016041070A (ja) 2016-03-31

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