CN102579287A - Cosmetic composition for repairing corneous layer of skin - Google Patents
Cosmetic composition for repairing corneous layer of skin Download PDFInfo
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- CN102579287A CN102579287A CN2012100912342A CN201210091234A CN102579287A CN 102579287 A CN102579287 A CN 102579287A CN 2012100912342 A CN2012100912342 A CN 2012100912342A CN 201210091234 A CN201210091234 A CN 201210091234A CN 102579287 A CN102579287 A CN 102579287A
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- keratodermatitis
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Abstract
The invention discloses a cosmetic composition for repairing the corneous layer of skin. The cosmetic composition comprises an active ingredient, and a carrier component which can be contacted in cosmetology, wherein the active ingredient comprises the following components in percentage by mass: 30 to 60 percent of camellia oil, 20 to 50 percent of ceramide, 5 to 35 percent of cholesterol, 5 to 35 percent of higher aliphatic alcohol, 2 to 30 percent of lecithin, and 0.1 to 25 percent of vitamin and derivatives thereof. The absorptivity and the permeability of physiological lipids are improved by the cosmetic composition, and the cosmetic composition can well penetrate into clearances of cells and accelerates the recovery of a barrier function of the damaged corneous layer of the skin, so the state of the skin is improved. The cosmetic composition has a good market prospect.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of cosmetic composition of repairing keratodermatitis.
Background technology
Along with the development of medical science and cosmetic science, people begin more and more clearly to recognize that can the key problem of skin nursing be exactly keep the problem of stratum corneum barrier defencive function better.When stratum corneum barrier function was stablized, skin will show good health status.
Horny layer is positioned at the outermost layer of skin, from physiological significance, horny layer be prevent that the Skin Cell internal moisture from losing, the erosion of external microbe and chemical substance provides very effectively barrier action.In general, horny layer by the horn cell of 12～16 layers flat acellular nuclear overlap each other, mutual restriction arranges and to form, folder forms the horny layer particular structure with lipidic matrix between each layer horn cell.The main lipid of horny layer comprises ceramide (40-50%), cholesterol (about 25%), free fatty (about 25%), cholesterol sulfate (about 5%) and small amounts of phosphoric acid etc.Up-to-date research is thought; Skin aging, the change of horn cell hydratability, the variation of skin surface pH value etc. all can cause the imbalance of horny layer function; Skin problem such as dry, coarse then is the outward manifestation of horny layer functional disorder; Just can not well change the drying regime of skin if merely keep the skin wet to skin this moment, and what is more important reaches recovery and keeps normal stratum corneum barrier function through replenishing cuticular lipid components.
It is very important in time carrying out the stratum corneum barrier reparation with suitable physiological lipid; But in the prior art; Because problems such as absorption, infiltration; Cause additional physiological lipid ceramide, raw material availabilities such as cholesterol are on the low side, and the stratum corneum barrier repairing effect is also failed to reach gratifying degree.
Summary of the invention
The technical problem that the present invention mainly solves provides a kind of cosmetic composition of repairing keratodermatitis, and it has the fabulous effect that alleviates for pachylosis.
For solving the problems of the technologies described above; The technical scheme that the present invention adopts is: a kind of cosmetic composition of repairing keratodermatitis; Comprise the carrier components that can contact on active component and the cosmetology, by percentage to the quality, each constituent proportioning is in the said active component:
Camellia oil 30-60%;
Ceramide 20-50%;
Cholesterol 5-35%;
High fatty alcohol class 5-35%;
Lecithin class 2-30%;
Vitamin and derivant 0.1-25% thereof.
In preferred embodiment of the present invention, by percentage to the quality, each constituent proportioning is in the said active component:
Camellia oil 30-50%;
Ceramide 20-40%;
Cholesterol 10-30%;
High fatty alcohol class 10-30%;
Lecithin class 5-25%;
Vitamin and derivant 1-20% thereof.
In preferred embodiment of the present invention, described high fatty alcohol class is one or more the mixture in spermol, stearyl alcohol, cetearyl alcohol, the behenyl alcohol.
In preferred embodiment of the present invention, described lecithin class is included as one or more the mixture in soybean lecithin, Ovum Gallus domesticus Flavus lecithin and the hydrolecithin.
In preferred embodiment of the present invention, in the described cosmetic composition, described active component accounts for 0.5-10%, the carrier components 90-99.5% that can contact on the cosmetology.
In preferred embodiment of the present invention, described cosmetic composition is an emulsified make-up, comprises oil-in-water type emulsion system or water-in-oil emulsion system.
In preferred embodiment of the present invention, described cosmetic composition is a kind of in cream frost, emulsion or the essence.
The invention has the beneficial effects as follows: the present invention adopts physiological lipid compatibilities such as derivants such as Camellia oil, vitamin and ceramide, lecithin, cholesterol, higher fatty acids; The absorbability and the permeability of physiological lipid have been improved; Can finely dissolve in intercellular substance; Quicken the skin damage horny layer and recover its barrier function, thereby improve skin condition.Possesses good market prospect.
The specific embodiment
A kind of cosmetic composition of repairing keratodermatitis comprises the carrier components that can contact on active component and the cosmetology, and by percentage to the quality, each constituent proportioning is in the said active component:
Camellia oil 30-60%;
Ceramide 20-50%;
Cholesterol 5-35%;
High fatty alcohol class 5-35%;
Lecithin class 2-30%;
Vitamin and derivant 0.1-25% thereof.
In the present invention, by percentage to the quality, each constituent optimum ratio is in the said active component:
Camellia oil 30-50%;
Ceramide 20-40%;
Cholesterol 10-30%;
High fatty alcohol class 10-30%;
Lecithin class 5-25%;
Vitamin and derivant 1-20% thereof.
In the present invention, the high fatty alcohol class is one or more the mixture in spermol, stearyl alcohol, cetearyl alcohol, the behenyl alcohol; The lecithin class is included as one or more the mixture in soybean lecithin, Ovum Gallus domesticus Flavus lecithin and the hydrolecithin; In the cosmetic composition, active component accounts for 0.5-10%, the carrier components 90-99.5% that can contact on the cosmetology; Cosmetic composition comprises oil-in-water type emulsion system or water-in-oil emulsion system for adopting emulsified make-up, is preferably cream frost, emulsion or essence.
Embodiment 1
(1) set of dispense ratio:
Camellia oil 30%;
Ceramide 50%;
Cholesterol 5%;
High fatty alcohol class 5%;
Lecithin class 3%;
Vitamin and derivant 7% thereof.
Under 80-90 ℃ condition, melt according to aforementioned proportion Camellia oil, ceramide, cholesterol, high fatty alcohol class, lecithin, vitamin and derivant thereof, mix homogeneously is made active component, and following said composition abbreviates LLQ as.
LLQ is applied in the emulsion, and the LLQ composition accounts for 10%, the carrier components 90% that can contact on the cosmetology.
Embodiment 2
(1) set of dispense ratio:
Camellia oil 30%;
Ceramide 3 0%;
Cholesterol 15%;
High fatty alcohol class 15%;
Lecithin class 8%;
Vitamin and derivant 2% thereof.
Under 80-90 ℃ condition, melt according to aforementioned proportion Camellia oil, ceramide, cholesterol, high fatty alcohol class, lecithin, vitamin and derivant thereof, mix homogeneously is made active component, and following said composition abbreviates LLQ as.
LLQ is applied in the essence, and the LLQ composition accounts for 3%, the carrier components 97% that can contact on the cosmetology.
Embodiment 3
(1) set of dispense ratio:
Camellia oil 30%;
Ceramide 3 0%;
Cholesterol 15%;
High fatty alcohol class 15%;
Lecithin class 8%;
Vitamin and derivant 2% thereof.
Under 80-90 ℃ condition, melt according to aforementioned proportion Camellia oil, ceramide, cholesterol, high fatty alcohol class, lecithin, vitamin and derivant thereof, mix homogeneously is made active component, and following said composition abbreviates LLQ as.
LLQ is applied in the skin ointment frost, and the LLQ composition accounts for 5%, the carrier components 95% that can contact on the cosmetology.
Embodiment 4 effect measurings
Keratodermatitis is positioned at the outermost layer of skin, has barrier actions such as the cell of preventing moisture loss, external substance erosion, in case horny layer is destroyed, water and ability variation, problem such as aging will appear in cell.Therefore measure the situation that skin moisture loss in horny layer water content, unit interval can reflect keratodermatitis to a certain extent.
As sample B, A contrasts with sample with the white sample of the cream of embodiment 3
| ? | Sample A (contrast) | Sample B (embodiment 3) |
| Montanov 68 | 2.5 | 2.5 |
| Stearoyl-glutamic acid sodium | 0.3 | 0.3 |
| Glyceryl stearate | 1.0 | 1.0 |
| LLQ | —— | 5.0 |
| Dicaprylyl carbonate | 5.0 | 5.0 |
| Polydimethylsiloxane | 2.0 | 2.0 |
| HANSHENGJIAO | 0.3 | 0.3 |
| Glycerol | 8.0 | 8.0 |
| Water | TO 100 | TO 100 |
Moisture of skin tester (Multi Skin Test Center MC 750; Germany CK) test philosophy: because glassware for drinking water has very high dielectric constant; Be higher than other materials far away, after test probe and contact skin, the variation of capacitance (F) can reflect the water content in the keratodermatitis; The horny layer water content is high more, and its capacitance is also high more.All tests are all carried out in the laboratory of constant temperature, constant humidity, temperature (22 ± 1) ℃, humidity (50 ± 5) %.
Xerodermatic 20 experimenters, 23 ~ 51 years old age, average out to 44 years old.At first respectively delimit two zones, be labeled as respectively No. 1 and No. 2 zones, measure the capacitance in these two zones with the moisture of skin tester in experimenter's both hands forearm inboard.Be that sample A (smears sample A, 2 mg/cm twice every day with No. 1 and No. 2 regional random process respectively
2), sample B (smears sample B, 2 mg/cm twice every day
2), used continuously 10 days, measure skin moisture content every day.
Table 1 skin moisture content test result (x ± s, n=40)
| Time (d) | A | B |
| 0 | 23.80±2.73 | 22.81±3.51 |
| 1 | 25.39±3.19 | 24.02±2.88 |
| 2 | 25.24±2.54 | 25.81±2.89 |
| 3 | 25.68±3.18 | 26.47±3.86 |
| 4 | 26.21±3.95 | 27.78±3.42 |
| 6 | 27.59±3.83 | 31.52±2.57* |
| 8 | 27.47±3.52 | 34.15±2.84* |
| 10 | 27.93±3.36 | 36.77±3.73* |
Sample B and sample A compare, * P < 0.05
Using the B product after 6 days; This zone skin moisture content is higher, and is remarkable with the regional comparing difference that uses sample A, has statistical significance (P < 0.05); Explain that the sample that contains LLQ can obviously improve the keratodermatitis water content, the sample that promptly contains LLQ can help horny layer to recover.
The above is merely embodiments of the invention; Be not so limit claim of the present invention; Every equivalent structure or equivalent flow process conversion that utilizes description of the present invention to do; Or directly or indirectly be used in other relevant technical fields, all in like manner be included in the scope of patent protection of the present invention.
Claims (7)
1. cosmetic composition of repairing keratodermatitis comprises the carrier components that can contact on active component and the cosmetology, it is characterized in that by percentage to the quality, each constituent proportioning is in the said active component:
Camellia oil 30-60%;
Ceramide 20-50%;
Cholesterol 5-35%;
High fatty alcohol class 5-35%;
Lecithin class 2-30%;
Vitamin and derivant 0.1-25% thereof.
2. the cosmetic composition of reparation keratodermatitis according to claim 1 is characterized in that, by percentage to the quality, each constituent proportioning is in the said active component:
Camellia oil 30-50%;
Ceramide 20-40%;
Cholesterol 10-30%;
High fatty alcohol class 10-30%;
Lecithin class 5-25%;
Vitamin and derivant 1-20% thereof.
3. the cosmetic composition of reparation keratodermatitis according to claim 1 and 2 is characterized in that, described high fatty alcohol class is one or more the mixture in spermol, stearyl alcohol, cetearyl alcohol, the behenyl alcohol.
4. the cosmetic composition of reparation keratodermatitis according to claim 1 and 2 is characterized in that, described lecithin class is included as one or more the mixture in soybean lecithin, Ovum Gallus domesticus Flavus lecithin and the hydrolecithin.
5. the cosmetic composition of reparation keratodermatitis according to claim 1 and 2 is characterized in that, in the described cosmetic composition, described active component accounts for 0.5-10%, the carrier components 90-99.5% that can contact on the cosmetology.
6. according to the cosmetic composition of any described reparation keratodermatitis of claim 1 to 5, it is characterized in that described cosmetic composition is an emulsified make-up, comprise oil-in-water type emulsion system or water-in-oil emulsion system.
7. the cosmetic composition of reparation keratodermatitis according to claim 6 is characterized in that, described cosmetic composition is a kind of in cream frost, emulsion or the essence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201210091234.2A CN102579287B (en) | 2012-03-31 | 2012-03-31 | Cosmetic composition for repairing corneous layer of skin |
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| CN201210091234.2A CN102579287B (en) | 2012-03-31 | 2012-03-31 | Cosmetic composition for repairing corneous layer of skin |
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| CN102579287A true CN102579287A (en) | 2012-07-18 |
| CN102579287B CN102579287B (en) | 2015-01-28 |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908268A (en) * | 2012-10-19 | 2013-02-06 | 伊国群 | Camellia type skin care solution |
| CN103565673A (en) * | 2013-10-30 | 2014-02-12 | 广州品赫化妆品有限公司 | Emollient lotion for moisturizing skin and controlling oil and preparation method of emollient lotion |
| CN105078778A (en) * | 2015-07-14 | 2015-11-25 | 拉芳家化股份有限公司 | Anti-dandruff shampoo capable of repairing scalp microecological system and application of anti-dandruff shampoo |
| CN105310945A (en) * | 2015-12-15 | 2016-02-10 | 钟苏 | Skin repair mask cream and preparation method thereof |
| CN107822939A (en) * | 2017-12-19 | 2018-03-23 | 广东真丽斯化妆品有限公司 | A kind of potent moisturiser and preparation method thereof |
| CN110013445A (en) * | 2019-03-21 | 2019-07-16 | 珠海金肽生物科技有限公司 | A kind of bionical sebum composition for skin barrier reparation |
| CN110123661A (en) * | 2019-05-23 | 2019-08-16 | 广州科斯曼生物科技有限公司 | A kind of anti-inflammatory anti-wrinkle composition of the moisturizing comprising ceramide and its preparation method and application |
| CN110302063A (en) * | 2019-07-05 | 2019-10-08 | 中山中研化妆品有限公司 | A kind of Moisturizer containing layered liquid crystal bionic structure film |
| CN111184656A (en) * | 2020-01-22 | 2020-05-22 | 杭州千岛湖天鑫有限公司 | Skin barrier repair micro-nano emulsion containing camellia oil and preparation method thereof |
| CN112512484A (en) * | 2018-08-08 | 2021-03-16 | 苏比品牌公司 | Cosmetic base composition and related cosmetic composition |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908268A (en) * | 2012-10-19 | 2013-02-06 | 伊国群 | Camellia type skin care solution |
| CN102908268B (en) * | 2012-10-19 | 2014-11-05 | 伊国群 | Camellia type skin care solution |
| CN103565673A (en) * | 2013-10-30 | 2014-02-12 | 广州品赫化妆品有限公司 | Emollient lotion for moisturizing skin and controlling oil and preparation method of emollient lotion |
| CN105078778A (en) * | 2015-07-14 | 2015-11-25 | 拉芳家化股份有限公司 | Anti-dandruff shampoo capable of repairing scalp microecological system and application of anti-dandruff shampoo |
| CN105078778B (en) * | 2015-07-14 | 2017-12-26 | 拉芳家化股份有限公司 | A kind of anti-dandruff lotion for repairing scalp microecosystem |
| CN105310945A (en) * | 2015-12-15 | 2016-02-10 | 钟苏 | Skin repair mask cream and preparation method thereof |
| CN107822939A (en) * | 2017-12-19 | 2018-03-23 | 广东真丽斯化妆品有限公司 | A kind of potent moisturiser and preparation method thereof |
| CN112512484A (en) * | 2018-08-08 | 2021-03-16 | 苏比品牌公司 | Cosmetic base composition and related cosmetic composition |
| CN110013445A (en) * | 2019-03-21 | 2019-07-16 | 珠海金肽生物科技有限公司 | A kind of bionical sebum composition for skin barrier reparation |
| CN110123661A (en) * | 2019-05-23 | 2019-08-16 | 广州科斯曼生物科技有限公司 | A kind of anti-inflammatory anti-wrinkle composition of the moisturizing comprising ceramide and its preparation method and application |
| CN110302063A (en) * | 2019-07-05 | 2019-10-08 | 中山中研化妆品有限公司 | A kind of Moisturizer containing layered liquid crystal bionic structure film |
| CN111184656A (en) * | 2020-01-22 | 2020-05-22 | 杭州千岛湖天鑫有限公司 | Skin barrier repair micro-nano emulsion containing camellia oil and preparation method thereof |
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| CN102579287B (en) | 2015-01-28 |
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Effective date of registration: 20200420 Address after: 215500 Xinzhuang section, provincial road 227, Changshu City, Suzhou City, Jiangsu Province Patentee after: Suzhou Crowley Cosmetics Co., Ltd. Address before: 215555 long nilfisk bio Industrial Park, Suzhou, Jiangsu, Changshu Patentee before: JIANGSU LONGRICH BIOTECH Co.,Ltd. |
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Address after: 215500 Xinzhuang section of 227 provincial road, Changshu City, Suzhou City, Jiangsu Province Patentee after: Crowley Cosmetics Co.,Ltd. Address before: 215500 Xinzhuang section of 227 provincial road, Changshu City, Suzhou City, Jiangsu Province Patentee before: Suzhou Crowley Cosmetics Co.,Ltd. |