CN102481332A - 用于提高血小板水平的肽疗法 - Google Patents

用于提高血小板水平的肽疗法 Download PDF

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Publication number
CN102481332A
CN102481332A CN2010800359315A CN201080035931A CN102481332A CN 102481332 A CN102481332 A CN 102481332A CN 2010800359315 A CN2010800359315 A CN 2010800359315A CN 201080035931 A CN201080035931 A CN 201080035931A CN 102481332 A CN102481332 A CN 102481332A
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CN
China
Prior art keywords
thrombocytopenia
platelet
peptide
experimenter
peptides
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Pending
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CN2010800359315A
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English (en)
Chinese (zh)
Inventor
米哈尔·亚伯拉罕
阿蒙·佩勒德
奥尔利·艾森贝格
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Biokine Therapeutics Ltd
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Biokine Therapeutics Ltd
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Publication of CN102481332A publication Critical patent/CN102481332A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/196—Thrombopoietin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN2010800359315A 2009-06-14 2010-06-13 用于提高血小板水平的肽疗法 Pending CN102481332A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18685709P 2009-06-14 2009-06-14
US61/186,857 2009-06-14
PCT/IL2010/000466 WO2010146578A2 (en) 2009-06-14 2010-06-13 Peptide therapy for increasing platelet levels

Publications (1)

Publication Number Publication Date
CN102481332A true CN102481332A (zh) 2012-05-30

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ID=43356827

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800359315A Pending CN102481332A (zh) 2009-06-14 2010-06-13 用于提高血小板水平的肽疗法

Country Status (11)

Country Link
US (1) US9427456B2 (OSRAM)
EP (1) EP2442822B1 (OSRAM)
JP (1) JP5715622B2 (OSRAM)
KR (1) KR101719339B1 (OSRAM)
CN (1) CN102481332A (OSRAM)
BR (1) BRPI1009663A2 (OSRAM)
CA (1) CA2765345C (OSRAM)
ES (1) ES2462517T3 (OSRAM)
IL (1) IL216912A (OSRAM)
MX (1) MX2011013459A (OSRAM)
WO (1) WO2010146578A2 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118027155A (zh) * 2024-04-15 2024-05-14 中国人民解放军军事科学院军事医学研究院 一种tpor结合肽及其应用

Families Citing this family (18)

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US8435939B2 (en) 2000-09-05 2013-05-07 Biokine Therapeutics Ltd. Polypeptide anti-HIV agent containing the same
ES2403932T3 (es) 2002-08-27 2013-05-22 Biokine Therapeutics Ltd. Antagonista de CXCR4 y uso del mismo
WO2008075370A2 (en) * 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for cancer therapy
US9427456B2 (en) 2009-06-14 2016-08-30 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
WO2012095849A1 (en) 2011-01-10 2012-07-19 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
JP2015154715A (ja) * 2012-05-22 2015-08-27 国立大学法人旭川医科大学 ヒト単核球由来の新規血管再生細胞群及びその分化誘導法
WO2014089478A1 (en) * 2012-12-07 2014-06-12 University Of Tennessee Research Foundation Methods of numerical analysis for platelet disorders and computer-readable media and systems for performing the same
AU2015258840B2 (en) 2014-05-15 2018-03-15 Enzychem Lifesciences Corporation Methods for treating leukopenia and thrombocytopenia
JP6547274B2 (ja) 2014-10-20 2019-07-24 株式会社デンソー 粒子状物質検出センサ
EP3744340A3 (en) 2015-07-16 2021-03-03 Biokine Therapeutics Ltd. Compositions and methods for treating cancer
US10993985B2 (en) 2016-02-23 2021-05-04 BioLmeRx Ltd. Methods of treating acute myeloid leukemia
JP2022523295A (ja) * 2019-01-25 2022-04-22 ヤンセン ファーマシューティカ エヌ．ベー． 発疱剤および苛性ガスの毒性作用を緩和する方法
WO2021181398A1 (en) * 2020-03-11 2021-09-16 Biolinerx Ltd. Cxcr4 inhibitor for the treatment of acute respiratory distress syndrome and viral infections
AU2021412499A1 (en) 2020-12-30 2023-08-10 Biokine Therapeutics Ltd. Composition of bl-8040
MX2023007868A (es) 2020-12-30 2023-07-10 Biolinerx Ltd Procedimiento de fabricacion de peptido.
WO2025259130A1 (ru) * 2024-06-11 2025-12-18 Consumer Cooperative "Vse" ПРИМЕНЕНИЕ ПЕПТИДА Ac-His-Ala-Glu-Glu-NH2 ДЛЯ ВОССТАНОВЛЕНИЯ ДЕФИЦИТА ЭНДОГЕННОГО КОМПОНЕНТА КРОВИ ЖИВОТНЫХ
WO2025259133A1 (ru) * 2024-06-11 2025-12-18 Федеральное государственное автономное образовательное учреждение высшего образования "Российский национальный исследовательский медицинский университет имени Н.И. Пирогова" Министерства здравоохранения Российской Федерации Пептид ac-his-ala-glu-glu-nh2 и его производные, предназначенные для восстановления дефицита эндогенного компонента крови человека

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WO2008075369A2 (en) * 2006-12-21 2008-06-26 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for bone marrow recovery

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118027155A (zh) * 2024-04-15 2024-05-14 中国人民解放军军事科学院军事医学研究院 一种tpor结合肽及其应用
CN118027155B (zh) * 2024-04-15 2024-07-16 中国人民解放军军事科学院军事医学研究院 一种tpor结合肽及其应用

Also Published As

Publication number Publication date
JP2012530130A (ja) 2012-11-29
CA2765345C (en) 2016-06-21
WO2010146578A2 (en) 2010-12-23
WO2010146578A3 (en) 2011-02-10
IL216912A0 (en) 2012-02-29
US20120094907A1 (en) 2012-04-19
BRPI1009663A2 (pt) 2016-10-11
US9427456B2 (en) 2016-08-30
MX2011013459A (es) 2012-05-08
JP5715622B2 (ja) 2015-05-07
EP2442822B1 (en) 2014-03-05
EP2442822A4 (en) 2013-01-23
ES2462517T3 (es) 2014-05-23
CA2765345A1 (en) 2010-12-23
KR20120037463A (ko) 2012-04-19
KR101719339B1 (ko) 2017-03-23
EP2442822A2 (en) 2012-04-25
IL216912A (en) 2015-09-24

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Application publication date: 20120530