CN102459554A - 采用直接掺入浓缩型表面活性剂制备清洁组合物的方法 - Google Patents
采用直接掺入浓缩型表面活性剂制备清洁组合物的方法 Download PDFInfo
- Publication number
- CN102459554A CN102459554A CN2010800253700A CN201080025370A CN102459554A CN 102459554 A CN102459554 A CN 102459554A CN 2010800253700 A CN2010800253700 A CN 2010800253700A CN 201080025370 A CN201080025370 A CN 201080025370A CN 102459554 A CN102459554 A CN 102459554A
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- China
- Prior art keywords
- water
- weight
- alkyl
- lauryl
- phase
- Prior art date
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 20
- 239000007788 liquid Substances 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 15
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 14
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 12
- 238000010008 shearing Methods 0.000 claims description 12
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 3
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- MRUAUOIMASANKQ-UHFFFAOYSA-O carboxymethyl-[3-(dodecanoylamino)propyl]-dimethylazanium Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(O)=O MRUAUOIMASANKQ-UHFFFAOYSA-O 0.000 description 2
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- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
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- DWHIUNMOTRUVPG-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCO DWHIUNMOTRUVPG-UHFFFAOYSA-N 0.000 description 1
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Abstract
本发明申请提出的方法使层状相中的浓缩型表面活性剂通过高剪切装置,将层状相中的浓缩型表面活性剂稀释至各向同性相,而不遭遇高度粘稠的中间相。
Description
技术领域
本发明描述了采用直接掺入浓缩型表面活性剂来制备清洁组合物的方法。
背景技术
用于清洁组合物中的许多常见表面活性剂很难以浓缩形式处理。具体地讲,众所周知,一些表面活性剂如烷基硫酸盐和烷基醚硫酸盐在大约30重量%至60重量%表面活性剂范围内呈现出极其粘稠的含水浓缩物凝胶相或“中间相”,同时在稍高浓度下呈现出稠厚但是可流动的层状相。
为了节省运输和储存成本,优选以浓缩形式处理这些材料。然而,为了将层状相稀释成各向同性相,必须小心以避免生成中间相或中相。一旦形成中间相,可能需要数小时至数天来稀释高度粘稠的该相,此外由于缓慢的混合动力学,使得经由简单叶轮混合的层状相稀释不可实用于工业规模。通常在中间体组合物形成难处理的中间相之前,使用高能装置将局部区域的中间体组合物破碎,并且必须小心成分加入的顺序,以避免组合物位于中间相内。
本领域已公开了若干方法,以将第二材料加入到层状表面活性剂中来减少中间相,所述第二材料通常为水溶助长剂如US 5,635,466中所述那些,但是已公开,其它表面活性剂如US 5,958,868中所述那些以及微粉化空气如JP2002-038200A中所述那些在某些狭小范围的应用中是有效的。
在大多数其中加入另一种材料来减少中间相是不可取的情况下,常用的解决方法是使用特别的稀释剂非常小心地将层状相稀释于水中,所述稀释剂如在Seifen,Oele,Fette,Wachse(1977)(103(16),465-6,CODEN:SOFWAF:ISSN 0173-5500)中所公开的Bran-Luebbe。在该操作中,专门设计的泵以精确的流量比将水和层状表面活性剂递送至高剪切装置中,以将表面活性剂稀释至固定的浓度(通常~25%)。如US 2008/0139434A1中所述,这种高剪切稀释到水中的方法可扩展至层状表面活性剂共混物;然而,使用该共混物,不必要地将所制备的所有产物中共混表面活性剂的组成比率固定在特定位置。由于水相的低粘度、表面活性剂相的高粘度、以及绝对避免在相图中间相中形成组合物的流量比要求,因此需要非常专业的泵。实际上,在某些情况下,对特定稀释体系的要求,超过了将高活性形式的表面活性剂运输到清洁产品生产设施所带来的成本节约,因此仅生产稀释形式的表面活性剂。
值得注意的是,在本领域公开的所有层状表面活性剂稀释方法中,稀释介质主要为水,可能是因为水相中存在的其它成分可以不可预见的方式改变相化学和混合动力学。尤其是在制备最终表面活性剂浓度低的组合物时,单独实施稀释步骤是减少操作不确定性的逻辑选择。然而,存在一些情况,其中在表面活性剂稀释期间,水相中存在显著量的其它成分实际上是优选的。
已惊奇地发现,清洁组合物中的许多常用成分实际上不是将浓缩型层状表面活性剂成功稀释的阻碍,前提条件是小心地控制稀释操作中的流量比。实际上,这些含水成分的增粘特点可改善对避免产生中间相而言关键性的流量比控制。本发明实施的关键性突破是理解不仅仅包含水的水相对表面活性剂相行为的影响,以及从而对流量比范围的影响,所述流量比范围可获得离开混合设备的可接受的清洁组合物或清洁组合物基料。
本发明消除了对单独稀释操作的需要,并且使清洁组合物中多种组分的相对组成具有最大的灵活性。专业技术人员将认识到,本文所述方法使通常严格限制用于稀释层状相的水可用于其它用途,如聚合物水合,或使其它组分更易于混入到清洁组合物中。在一些情况下,所述方法还允许低温处理以获得最终的清洁组合物。此外,当最终清洁组合物中期望高浓度的表面活性剂时,本发明方法通过允许清洁组合物中包含更高含量的其它成分,并且延迟那些成分的加入来改进当前领域,从而使可行制剂和生产设备处的物流操作范围更广泛。使成分稍后加入到所述过程中,可有利于剪切敏感性成分,并且在制备彼此仅稍稍不同的若干产品时有助于改善物流操作。
发明简介
本专利申请涉及制备液体清洁组合物的方法,所述方法包括下列步骤:提供包含水和至少一种其它组分的水相,所述其它组分选自阴离子表面活性剂、辅助表面活性剂、调理聚合物、沉积聚合物;在层状相中提供表面活性剂,其中所述层状相包含所述层状相中约50%至80%的一种或多种活性表面活性剂;在高剪切装置中按水相与层状相的流量比混合所述水相和所述层状相,以获得如下液体清洁组合物,其中所述液体清洁组合物在1mm长度标度下是均匀的,并且在1/sec剪切速率下具有小于100Pa-s的粘度。
附图简述
图1是水、29%月桂基硫酸钠和(层状)70%月桂基聚氧乙烯醚-1硫酸钠的相图。
图2是图1中的相图,其中示出了已知方法和本文所述并且受权利要求书保护的方法在所述相图中的理论移动。
发明详述
本专利申请提出的方法使层状相中的浓缩型表面活性剂通过高剪切装置,将层状相中的浓缩型表面活性剂稀释至各向同性相,而不遭遇高度粘稠的中间相。
此外,已发现,在所提出的小心控制水相与层状相流量比的方法中,可经由高能混合将所述层状相直接稀释到清洁组合物中;即将层状相物流中的浓缩型表面活性剂与已经包含不同于水的组分的水相物流混合。实际上,水相中存在非水组分,改善了水相的泵送能力,扩宽了能够实施关键性稀释操作的设备范围,使得稀释步骤能够在与其它更常规设备操作共用的设备中实施。
本发明的关键在于确定这些非水水相组分对致使成功稀释的流量比的影响。优选使用旨在制备产品的实际设备,或在研究实验室中常见的比例缩小型生产设备上进行测定。如下文实施例中所示的方法是以不同的水相与层状相流量比,将本发明的水相和层状表面活性剂泵送到高剪切混合设备中。然后收集离开混合器的组合物,并且分析测定所考虑的每种流量比下稀释实验的成功情况。
成功稀释是指由含水物流与浓缩型表面活性剂层状相物流混合所得的物流在1mm长度标度下是均匀的,并且在1/sec剪切速率下表现出小于100Pa-s的粘度,以致可充分流动用于下游加工操作。将需要最低能量来达到所期望的均匀度,并且专业技术人员将认识到,该最低能量将取决于所用的高能混合器以及所研究的组合物。最好将测定粘度的温度确定为制备期间生产线上稀释操作的温度。就其中两股进料物流处于不同温度的情况而言,如提高一种组分相(例如高熔点组分)流动性的情况,适宜的温度是混合组合物的温度。例如,室温下实施的方法将具有25℃下测得的粘度。高加工温度将致使粘度在高于25℃的温度例如40℃下测定。
本领域的专业技术人员将认识到,本发明可在一定的流量比范围内产生效果,但是通常期望保持尽可能低的比率以使稀释过程所需的水相量最小化,对于更浓的清洁组合物而言尤其如此。因此,我们定义“最小流量比”(MFR)为恰好满足上段所述粘度阈值的比率。
在一个实施方案中,测定包含高含量表面活性剂(按所述组合物的重量计大于20重量%)的清洁制剂流量比。图1示出了70%月桂基聚氧乙烯醚-1硫酸钠(SLE1S)、29%月桂基硫酸钠和水的混合物的相行为,按所加入的基准绘制。
从水、29%月桂基硫酸钠和(层状)70%月桂基聚氧乙烯醚-1硫酸钠三部分混合物的图1表示中可以看出,在一定的组成范围内形成凝胶相。该“中间相”(1)是高度粘稠的并且难以溶解,如果遭遇该相,则生产过程中需要额外的能量,并且时间延长。其它相包括层状相(2)和各向同性相(3)。在本文所述方法的一个实施方案中,以一定的方式将SLE1S加入到水相混合物中以避免“中间相”。
高剪切装置中表面活性剂的活性浓度必须小于各向同性相和中间相之间的边界;同样,该边界可主要取决于某些水相成分的含量。相反,如果流量比使得表面活性剂过稀(水更多),则最终产品中不可能达到所期望的表面活性剂活性。通常,进入高剪切装置的流量比将介于所考虑组合物MFR的1.0至3.0倍之间。
图2中注意到本文方法与先前方法在表面活性剂稀释方面的区别,并且本文所述方法能够获得采用首先稀释层状表面活性剂的常规方法无法获得的某些具有高含量表面活性剂的组合物(按所述组合物的重量计大于20重量%)(4)。
如本文所用,“高剪切装置”是混合物通过所述装置时向所述混合物赋予最低即3kJ/kg能量密度的装置。就旋转装置(例如IKA转子-定子研磨)而言,能通过用功耗除以质量流量大致计算出来。就静态装置(例如静态混合器或)而言,可按装置上的压力损失除以材料密度计算出能级。在一个实施方案中,所述高剪切装置为转子/定子研磨或类似的动态混合器,其中流体通过约0.1mm至约20mm的间隙,并且旋转端速可设为约5至约50米每秒。在另一个实施方案中,所述高剪切装置选为静态混合器,这是指由材料流动通过所述装置自然引起其能量耗散的混合设备,其中通过所述装置赋予的能量密度为10-10,000J/kg。
在一个实施方案中,所述方法在单程通过混合设备时发生。在另一个实施方案中,将层状表面活性剂加入到再循环管线中,其中收集高剪切装置的输出物,并且以与附加层状表面活性剂的可控流量比再循环到高剪切装置中。在另一个实施方案中,将层状表面活性剂加入到再循环管线中。在另一个实施方案中,将水相至少部分地加入到再循环管线中。在另一个实施方案中,使水相至少部分地通过高剪切装置,并且至少部分地加入到高剪切装置后的液体清洁组合物中。
由本文所述方法获得的清洁组合物等价于浓缩型清洁组合物。如本文所用,“浓缩”是指本发明方法的所得清洁组合物以二分之一至三分之一的用量提供与相似类型的传统清洁组合物相同或更好的性能。
适宜的清洁组合物包括毛发清洁组合物如洗发剂、沐浴剂组合物和洗手皂组合物。
虽然本发明可降低或消除对减少中间相的水溶助长剂的需要,但是专业技术人员将认识到,本发明可与存在于任一相中或稍后加入的水溶助长剂结合使用,以控制最终产品的粘度。可用上述相同技术,评定水溶助长剂对相图以及MFR的影响。如本文所用,术语“有机溶剂”和“水溶助长剂”包括本领域认为是有机溶剂或水溶助长剂的那些物质。有机溶剂的实例包括用于清洁应用的那些,并且可选自由下列组成的组:醇、二醇、醚、醚醇、以及它们的混合物。典型的水溶助长剂可包括异丙基苯磺酸盐、二甲苯磺酸盐和甲苯磺酸盐、以及它们的混合物。溶剂和水溶助长剂实例概述于McCutcheon’s“Detergents and Emulsifiers”北美版(1986年,由AlluredPublishing Corporation公布);和McCutcheon’s“Functional Materials”北美版(1992年)中。
层状相中的浓缩型表面活性剂
适用于本文的层状相中的浓缩型表面活性剂包括具有式ROSO3M和RO(C2H4O)xSO3M的烷基硫酸盐和烷基醚硫酸盐,其中R为具有约8至约18个碳原子的烷基或烯基,x为1至10,并且M为水溶性阳离子如铵、钠、钾和三乙醇胺阳离子,或具有两个阴离子表面活性剂阴离子的二价镁离子的盐。
烷基醚硫酸盐可作为环氧乙烷与具有约8至约18个碳原子的一元醇的缩合产物。所述醇可衍生自脂肪,例如椰子油、棕榈油、棕榈仁油或牛油,或可合成制得。
适用于本文的附加阴离子表面活性剂的实例包括但不限于十二烷基硫酸铵、月桂基聚氧乙烯醚硫酸铵、月桂基硫酸三乙基胺、月桂基聚氧乙烯醚硫酸三乙基胺、月桂基硫酸三乙醇胺、月桂基聚氧乙烯醚硫酸三乙醇胺、月桂基硫酸单乙醇胺、月桂基聚氧乙烯醚硫酸单乙醇胺、月桂基硫酸二乙醇胺、月桂基聚氧乙烯醚硫酸二乙醇胺、月桂酸甘油单酯硫酸钠、月桂基硫酸钠、月桂基聚氧乙烯醚硫酸钠、月桂基聚氧乙烯醚硫酸钾、月桂基肌氨酸钠、月桂酰肌氨酸钠、肌氨酸月桂酯、椰油基肌氨酸、椰油基硫酸铵、十二烷酰基硫酸铵、椰油基硫酸钠、月桂酰硫酸钠、椰油基硫酸钾、月桂基硫酸钾、椰油基硫酸一乙醇胺、十三烷基聚氧乙烯醚硫酸钠、十三烷基硫酸钠、甲基月桂酰牛磺酸钠、甲基椰油基牛磺酸钠、月桂酰羟乙基磺酸钠、椰油基羟乙基磺酸钠、月桂基聚氧乙烯醚磺基琥珀酸钠、月桂基磺基琥珀酸钠、十三烷基苯磺酸钠、十二烷基苯磺酸钠、以及它们的混合物。
在一个实施方案中,使用月桂基聚氧乙烯醚硫酸铵或月桂基聚氧乙烯醚硫酸钠,其中获得具有平均0.7至3摩尔乙氧基部分每分子的环氧乙烷缩合产物。在一个实施方案中,选择具有平均1摩尔乙氧基部分每分子的月桂基聚氧乙烯醚硫酸铵或月桂基聚氧乙烯醚硫酸钠。
含水相组合物
除了水以外,清洁组合物中的水相还包含其它组分,如附加的阴离子表面活性剂、调理聚合物、沉积聚合物、辅助表面活性剂、调理剂、结构剂、遮光剂、香料或其它任选成分。
在一个实施方案中,所述组合物包含按所述组合物的重量计约3重量%至约40重量%,或约5重量%至约25重量%,或约10重量%至约20重量%,或约3重量%至约15重量%,或约3重量%至约10重量%的阴离子表面活性剂(不是层状相中的浓缩型表面活性剂)。
所述阴离子表面活性剂包括但不限于:乙氧基化或非乙氧基化的支化和非支化类型的癸基和十一烷基硫酸盐;癸醇改性的月桂基硫酸盐;由ClariantCompany出售的具有C13-C17链长的链烷磺酸盐;通常被称为和烷基硫酸盐或醇硫酸盐的乙氧基化或非乙氧基化的具有C12-C17碳链长度的直链和支链醇硫酸盐的混合物;羟乙基-2-十二烷基醚硫酸钠盐或羟乙基-2-癸基醚硫酸钠盐(得自Nippon Shokubai Inc.,并且任一种或二者在本文中被称为“NSKK乙氧基硫酸盐”);一乙氧基化月桂基烷基硫酸盐;以及它们的混合物。
调理聚合物
本文适用于水相的调理聚合物可包括阳离子聚合物。在清洁组合物的预期应用pH下,适宜的阳离子聚合物具有至少约0.3meq/gm,典型至少约0.5meq/gm,通常至少约0.7meq/gm,而且一般小于约7meq/gm,典型小于约5meq/gm的阳离子电荷密度。所述组合物的预期用途的pH一般在约pH 3至约pH 9,典型在约pH 4至约pH 8的范围内。适宜的阳离子聚合物将一般具有范围在约1,000至约10,000,000,典型约10,000至约5,000,000,通常约20,000至约2,000,000内的平均分子量。除非另外指明,本文所用的所有分子量为重量平均分子量,以克/摩尔表示。
可通过凝胶渗透色谱法(“GPC”),以30℃的柱温和0.9ml/min的流量,使用配备两根串联水凝胶柱(Waters Ultrahydrogel Linear,6至13um,7.8×300nm GPC柱,部件号011545)的Alliance HPLC(Waters 2695分离模块),并且使用检测器温度均为30℃的Viscotek 300型TDA(三元检测器阵列)、光散射检测器(单角度,90°)、粘度检测器和折射指数检测器,通过使用得自American Polymer Standards Corporation(Mw=788,000)的普鲁兰多糖窄标准物P-800以及25至100μl注射体积并且采用0.147的dn/dc而形成的方法,测定重均分子量。根据GPC方法测定重均分子量的其它详情描述于美国专利公布No.2003/0154883A1中。
本文所用术语“电荷密度”是指构成聚合物的单体单元上的正电荷数与所述单体单元的分子量的比率。电荷密度乘以聚合物分子量决定给定聚合物链上的正电荷位点数目。
适宜的阳离子聚合物可包含含有阳离子氮的部分,如季铵或阳离子质子化氨基部分。阳离子质子化的胺可以为伯胺、仲胺或叔胺(通常为仲胺或叔胺),其取决于组合物的具体类型和选定的pH。任何阴离子抗衡离子都可以与阳离子聚合物联合使用,只要该聚合物在水中、在清洁组合物中或在清洁组合物的凝聚层相中保持溶解,并且只要该抗衡离子与清洁组合物的组分在物理上和化学上是相容的,或换句话讲该抗衡离子不会不当地损害产品的性能、稳定性或美观性。此类抗衡离子的非限制性实施例包括卤素离子(例如氯离子、氟离子、溴离子、碘离子)、硫酸根和甲酯硫酸根。
上述聚合物的非限制性实例描述于Estrin、Crosley和Haynes编辑的CTFA Cosmetic Ingredient Dictionary,第三版,(The Cosmetic,Toiletry,andFragrance Association,Inc.,Washington,D.C.(1982年))。合适的阳离子聚合物的非限制性实施例包括具有阳离子质子化胺或季铵官能团的乙烯基单体与水溶性间隔单体的共聚物,所述水溶性间隔单体如丙烯酰胺、异丁烯酰胺、烷基丙烯酰胺和二烷基丙烯酰胺、烷基异丁烯酰胺和二烷基异丁烯酰胺、丙烯酸烷基酯、异丁烯酸烷基酯、乙烯基己内酯或乙烯基吡咯烷酮。
用于包括在本文的组合物的阳离子聚合物中的合适阳离子质子化氨基和季铵单体包括:用丙烯酸二烷基氨基烷基酯、异丁烯酸二烷基氨基烷基酯、丙烯酸单烷基氨基烷基酯、异丁烯酸单烷基氨基烷基酯、三烷基异丁烯酰氧基烷基铵盐、三烷基丙烯酰氧基烷基铵盐、二烯丙基季铵盐取代的乙烯基化合物,以及具有诸如吡啶、咪唑和季铵化吡咯烷酮等阳离子含氮环的乙烯基季铵单体,例如烷基乙烯基咪唑、烷基乙烯基吡啶、烷基乙烯基吡咯烷酮盐。
可用于所述组合物的其它合适阳离子聚合物包括:1-乙烯基-2-吡咯烷酮和1-乙烯基-3-甲基咪唑盐(例如,盐酸盐)的共聚物(在本行业被化妆品、梳妆用品和香料协会(Cosmetic,Toiletry,and Fragrance Association)“CTFA”,称为聚季铵盐-16);1-乙烯基-2-吡咯烷酮和二甲氨基甲基丙烯酸乙酯的共聚物(在本行业被CTFA称为聚季铵盐-11);含有阳离子二烯丙基季铵的聚合物,包括例如二甲基二烯丙基氯化铵均聚物、丙烯酰胺与二甲基二烯丙基氯化铵的共聚物(在本行业被CTFA分别称为聚季铵盐-6和聚季铵盐-7);丙烯酸的两性共聚物,包括丙烯酸与二甲基二烯丙基氯化铵的共聚物(在本行业被CTFA称为聚季铵盐-22)、丙烯酸与二甲基二烯丙基氯化铵和丙烯酰胺的三元共聚物(在本行业被CTFA称为聚季铵盐-39)以及丙烯酸与异丁烯酰氨基丙基三甲基氯化铵和异丁烯酸酯的三元共聚物(在本行业被CTFA称为聚季铵盐-47)。适宜的阳离子取代的单体为阳离子取代的二烷基氨基烷基丙烯酰胺、二烷基氨基烷基异丁烯酰胺以及它们的组合。这些适宜的单体符合式(III):
其中式(III)中的R1为氢、甲基或乙基;式(III)中的R2、R3和R4各自独立地为氢或具有约1至约8个碳原子,典型约1至约5个碳原子,通常约1至约2个碳原子的短链烷基;式(III)中的n是值为约1至约8,典型约1至约4的整数;并且式(III)中的X为水溶性抗衡离子如卤离子。与式(III)中的R2、R3和R4连接的氮可以是质子化胺(伯胺、仲胺或叔胺),但是典型地为季铵,其中式(III)中的R2、R3和R4分别为烷基,其非限制性实例是可以商品名133得自Rhone-Poulenc(Cranberry,N.J.,U.S.A.)的聚甲基丙烯酰胺丙基三甲基氯化铵。
其它适用于组合物中的阳离子聚合物包括多糖聚合物,如阳离子纤维素衍生物和阳离子淀粉衍生物。适宜的阳离子多糖聚合物包括符合式(IV)的那些:
其中式(IV)中的A为葡糖酐残基,如淀粉或纤维素葡糖酐残基;式(IV)中的R为亚烷基氧化烯、聚氧化烯或羟亚烷基、或它们的组合;式(IV)中的R1、R2和R3独立地为烷基、芳基、烷基芳基、芳烷基、烷氧基烷基、或烷氧基芳基,每个基团包含至多约18个碳原子,并且每个阳离子部分的碳原子总数(即式(IV)中R1、R2和R3中的碳原子数之和)通常为约20或更少;并且式(IV)中的X为阴离子抗衡离子如卤离子。
通常,此类纤维素或瓜尔阳离子沉积聚合物的浓度含量按所得清洁组合物的重量计为约0.05重量%至约5重量%。适宜的纤维素或瓜尔阳离子沉积聚合物具有大于约5,000的分子量。此外,此类纤维素或瓜尔聚合物在个人护理组合物预期使用的pH下具有约0.5meq/g至约4.0meq/g的电荷密度,所述pH一般在约pH 3至约pH 9,优选约pH 4至约pH 8的范围内。所述组合物的pH是以纯态测定的。
在一个实施方案中,阳离子聚合物是羟丙基瓜尔胶的衍生物,其实例包括已知由INCI命名为瓜尔羟丙基三甲基氯化铵的聚合物,如以商品名CATINAL CG-100、CATINAL CG-200由公司Toho出售,以商品名COSMEDIA GUAR C-261N、COSMEDIA GUAR C-261N、COSMEDIA GUARC-261N由公司Cognis出售,以商品名DIAGUM P 5070由公司FreedomChemical Diamalt出售,以商品名N-HANCE Cationic Guar由公司Hercules/Aqualon出售,以商品名HI-CARE 1000、JAGUAR C-17、JAGUARC-2000、JAGUAR C-13S、JAGUAR C-14S、JAGUAR EXCEL由公司Rhodia出售,以商品名KIPROGUM CW、KIPROGUM NGK由公司Nippon Starch出售的产品。适宜的阳离子纤维素聚合物是羟乙基纤维素与三甲基铵取代的环氧化物反应得到的盐,工业上(CTFA)称作聚季铵盐10,并且可以它们的Polymer LR、JR和KG聚合物系列得自Amerchol Corp.(Edison,N.J.,USA)。阳离子纤维素的其它适宜类型包括羟乙基纤维素与月桂基二甲基铵取代的环氧化物反应而生成的聚合物季铵盐,其在工业领域(CTFA)内被命名为聚季铵盐24。这些物质以商品名Polymer LM-200得自Amerchol Corp.。
其它合适的阳离子聚合物包括阳离子瓜尔胶衍生物,如瓜尔羟丙基三甲基氯化铵,其具体的实施例包括市售自Rhone-Poulenc Incorporated的Jaguar系列和市售自Aqualon Division of Hercules,Inc.的N-Hance系列。
其它适宜的阳离子聚合物包括含季氮的纤维素醚,其一些实例描述于U.S.3,962,418中。其它适宜的阳离子聚合物包括醚化纤维素、瓜尔胶和淀粉的共聚物,其一些实例描述于U.S.3,958,581中。
当使用时,将本文的阳离子聚合物溶于组合物或者溶于组合物中的复合凝聚层相,该凝聚层相是由本文上述的阳离子聚合物与去污表面活性剂组分形成。阳离子聚合物的复合凝聚层也能与组合物中的其它带电物质形成。
沉积聚合物
本文中可用于水相的沉积聚合物可包括US 2007/0207109A1和US2008/0206185A1中所述的那些,如具有足够高的分子量的合成共聚物,以有效增强本文所述个人护理组合物中的调理活性物质组分的沉积。还可使用阳离子聚合物的组合。合成共聚物的平均分子量一般介于约10,000和约10百万之间,优选介于约100,000和约3百万之间,还更优选介于约200,000和约2百万之间。
在另一个实施方案中,所述合成共聚物在清洁组合物预期应用的pH下具有约0.1meq/gm至约6.0meq/gm,并且更优选约0.5meq/gm至约3.0meq/gm的质量电荷密度。pH一般在约pH 3至约pH 9范围内,并且更优选介于约pH 4和约pH 8之间。
在另一个实施方案中,合成共聚物具有至少约2meq/A至约500meq/A,并且更优选约20meq/A至约200meq/A,并且最优选约25meq/A至约100meq/A的线性电荷密度。
阳离子聚合物可为共聚物或均聚物。在一个实施方案中,在本发明组合物中使用均聚物。在另一个实施方案中,在本发明组合物中使用共聚物。在另一个实施方案中,在本发明组合物中使用均聚物和共聚物的混合物。在另一个实施方案中,使天然源类型的均聚物(如本文所述的纤维素或瓜尔胶聚合物)与合成源均聚物或共聚物(如下述那些)组合。
均聚物-下列单体的非交联阳离子均聚物也可用于本文中:3-丙烯酰胺基丙基三甲基氯化铵(APTAC)、二烯丙基二甲基氯化铵(DADMAC)、[(3-甲基丙烯酰胺基)丙基]三甲基氯化铵(MAPTAC)、3-甲基-1-乙烯基氯化咪唑(QVI);[2-(丙烯酰氧基)乙基]三甲基氯化铵和[2-(丙烯酰氧基)丙基]三甲基氯化铵。
共聚物-共聚物可由两种阳离子单体或由非离子单体和阳离子单体构成。
非离子单体单元
适用于本文的共聚物包含由下式V表示的非离子单体单元:
i.
其中式(V)中的R为H或C1-4烷基;并且式(V)中的R1和R2独立地选自由下列组成的组:H、C1-4烷基、CH2OCH3、CH2OCH2CH(CH3)2和苯基,或合在一起为C3-6环烷基。
在一个实施方案中,非离子单体单元为丙烯酰胺(AM),即其中式(V)中的R、R1和R2为H,如下式(VI)中所示:
其中m等于1。
另一种优选的非离子单体单元是甲基丙烯酰胺(MethAM),即其中式(V)中的R为C1烷基,并且式(V)中的R1和R2分别为H:
其中m等于1。
然而,设想上文给出的化学式范围内的其它丙烯酰胺衍生物也是适宜的,其中聚丙烯酰胺和使用丙烯酰胺单体的共聚物是可用的。
共聚物中的非离子单体部分的含量按所述总共聚物的重量计为约50重量%至约99.5重量%。优选地,该量按所述共聚物的重量计为约70重量%至约99重量%,还更优选约80重量%至约99重量%。
阳离子单体单元
所述共聚物还包含由式(VIII)表示的阳离子单体单元:
式(VIII)
其中式(VIII)中的k为1,式(VIII)中的v、v′和v″各自独立地为1至6的整数,式(VIII)中的w为零或1至10的整数,并且式(VIII)中的X-为水溶性阴离子如卤离子。
在一个实施方案中,根据上式(VIII),存在一种结构,其中k=1,v=3并且w=0,并且X-为Cl-,形成下列结构:
上述结构可被称作二季铵。
由所形成的结构获得另一个实施方案,根据式(VIII),其中k=1,v和v″各为3,v′=1,w=1,并且X-为Cl-,如:
上述结构可被称作三季铵。
适宜的阳离子单体可通过例如美国专利申请公布2004/0010106A1中所述的方法制得。
聚合物增稠剂
依照本发明,液体清洁组合物包含聚合物增稠剂,所述增稠剂包含至少一种选自缔合聚合物、多糖、非缔合聚羧酸聚合物、以及它们的混合物的聚合物。
本领域的技术人员将认识到聚合物增稠体系通常通过链缠结、网络形成或微凝胶膨胀提供稠化。这些体系通常具有凝胶的外观和手感,因此非常令人满意。
可用于本文的优选的缔合聚合增稠剂包含至少一个亲水单元(该亲水单元为不饱和羧酸或其衍生物)和至少一个疏水单元(该疏水单元为不饱和羧酸C8-C30烷基酯或氧乙烯化C8-C30烷基酯)。不饱和羧酸优选丙烯酸、甲基丙烯酸或衣康酸。实施例可由以下物质制得:以商品名Aculy-22由Rohm & Haas公司销售的物质,以商品名Permulen TR1、Carbopol 2020、Carbopol Ultrez-21由Noveon公司销售的物质,和以商品名Structure 2001和Structure 3001由National Starch公司销售的物质。用于本发明的聚合物增稠体系的另一个优选的缔合聚合物包括聚醚聚氨酯,例如以商品名Aculyn-44和Aculyn-46由Rohm和Haas公司销售的物质。可用于本文的另一个优选的缔合聚合物为由包含至少一个C8-C30脂肪链的基团改性的纤维素,例如由公司Aqualon销售的产品NATROSOL PLUS GRADE 330CS。
可用于本文的非缔合交联聚羧酸聚合物可选自,例如:
(i)交联丙烯酸均聚物;
(ii)丙烯酸或(甲基)丙烯酸与丙烯酸或(甲基)丙烯酸的C1-C6烷基酯的共聚物。
优选的聚合物为以商品名CARBOPOL 980、981、954、2984、5984由公司Noveon销售的产品,或以商品名SYNTHALEN M、SYNTHALEN L和SYNTHALEN K由公司3V Sigma销售的产品,或以商品名ACULYN-33由公司Rohm and Haas销售的产品。
可用于本文的多糖选自,例如,葡聚糖、改性和未改性的淀粉(如衍生自例如谷类食物(如小麦、玉米或稻米)、植物(如豌豆黄)和块茎(如马铃薯或木薯)的那些)、直链淀粉、支链淀粉、肝糖、葡聚糖、纤维素以及它们的衍生物(甲基纤维素、羟烷基纤维素、乙基羟乙基纤维素和羧甲基纤维素)、甘露聚糖、木聚糖、木质素、阿拉伯聚糖、半乳聚糖、聚半乳糖醛酸苷、甲壳质、脱乙酰壳多糖、葡糖基木聚糖、阿拉伯糖基木聚糖、葡聚木糖、葡甘露聚糖、果胶酸和果胶、藻酸和藻酸酯、阿拉伯半乳聚糖、角叉菜胶、琼脂、葡糖胺聚糖、阿拉伯树胶、黄蓍胶、达瓦树胶、刺梧桐树胶、角豆荚树胶、半乳甘露聚糖如瓜尔胶及其非离子衍生物(羟丙基瓜尔胶)和生物多糖,例如黄原胶、结冷胶、文莱胶、小核菌葡聚糖、琥珀酰聚糖、以及它们的混合物。
例如,适宜的多糖描述于Kirk-Othmer的“Encyclopedia of ChemicalTechnology”第三版(1982)第3卷第896至900页,和第15卷第439-458,E.A.MacGregor和C.T.Greenwood的“Polymers in Nature”的第6章第240-328页(John Wiley & Sons公布,1980年),和Roy L.Whistler编辑的“Industrial Gums-Polysaccharides and their Derivatives”的第二版(AcademicPress Inc.公布)中。
辅助表面活性剂
辅助表面活性剂是适用于水相的材料,并且选择所述辅助表面活性剂以增强清洁组合物的泡沫体积和/或改善泡沫质感。通常这些物质可选自多类结构,包括但不限于两性的、两性离子的、阳离子的和非离子的。
得自本文方法的清洁组合物可包含按所述组合物的重量计约0.5重量%至约10重量%,或约0.5重量%至约5重量%,或约1重量%至约3重量%的至少一种适宜的辅助表面活性剂。
适用于本发明的两性表面活性剂包括但不限于脂族仲胺和叔胺的衍生物,其中脂族基团可以为直链或支链,并且其中脂族取代基中的一个取代基包含约8至约18个碳原子,而一个脂族取代基包含阴离子水增溶性基团,例如羧基、磺酸根、硫酸根、磷酸根或膦酸根。实例包括3-十二烷基氨基丙酸钠、3-十二烷基氨基丙磺酸钠、月桂基肌氨酸钠、N-烷基牛磺酸盐如根据U.S.2,658,072中的指导由十二烷基胺与羟乙基磺酸钠的反应制得的那些、N-高级烷基天冬氨酸如根据U.S.2,438,091中的指导制得的那些和U.S.2,528,378中描述的产物、以及它们的混合物。由氯乙酸钠与酰氨基胺反应制备烷酰基两性乙酸盐而获得的两性乙酸盐类型是尤其有效的,例如月桂酰基两性乙酸盐等等。
适用于本文的两性离子表面活性剂包括但不限于脂族季铵、和锍化合物的衍生物,其中脂族基团可以为直链或支链,并且其中一个脂族取代基包含约8个至约18个碳原子,并且一个脂族取代基包含阴离子基团,如羧基、磺酸根、硫酸根、磷酸根或膦酸根。适用于本文的其它两性离子表面活性剂包括甜菜碱,包括高级烷基甜菜碱如椰油基二甲基羧甲基甜菜碱、椰油酰氨基丙基甜菜碱、椰油基甜菜碱、月桂酰氨基丙基甜菜碱、油基甜菜碱、月桂基二甲基羧甲基甜菜碱、月桂基二甲基α-羧乙基甜菜碱、鲸蜡基二甲基羧甲基甜菜碱、月桂基二-(2-羟乙基)羧甲基甜菜碱、硬脂基二-(2-羟丙基)羧甲基甜菜碱、油基二甲基γ-羧丙基甜菜碱、月桂基二-(2-羟丙基)α-羧乙基甜菜碱、以及它们的混合物。磺基甜菜碱可包括椰油基二甲基磺基丙基甜菜碱、硬脂基二甲基磺基丙基甜菜碱、月桂基二甲基磺乙基甜菜碱、月桂基二-(2-羟基乙基)磺基丙基甜菜碱、以及它们的混合物。还适宜的两性离子表面活性剂包括酰氨基甜菜碱和氨基磺基甜菜碱,其中RCONH(CH2)3基团(其中R为C11-C17烷基)连接在甜菜碱的氮原子上,它们也可用于本专利申请中。
通常用于清洁组合物中以增加泡沫体积或质感的非离子辅助表面活性剂包括水溶性物质,如月桂基二甲基氧化胺、椰油基二甲基氧化胺、椰油酰氨基丙基氧化胺、月桂酰氨基丙基氧化胺等,或烷基多乙氧基化物如月桂基聚氧乙烯醚-4至月桂基聚氧乙烯醚-7,以及水不溶性组分如椰油基单乙醇酰胺、椰油基二乙醇酰胺、月桂酰单乙醇酰胺、烷酰基异丙醇酰胺,和脂肪醇如鲸蜡醇和油醇,以及2-羟烷基甲基醚等等。
还适用作本文辅助表面活性剂的物质包括1,2-烷基环氧化物、1,2-链烷二醇、支链或直链烷基甘油基醚(例如EP 1696023A1中公开的那些)、1,2-烷基环状碳酸酯和1,2-烷基环亚硫酸酯,尤其是其中烷基包含6至14个直链或支链构型的碳原子的那些。其它实例包括由C10或C12α烯烃与乙二醇的反应获得的烷基醚醇(例如羟基乙基-2-癸基醚、羟基乙基-2-十二烷基醚),如可根据U.S.5,741,948、U.S.5,994,595、U.S.6,346,509和U.S.6,417,408中的教导制得。
其它优选的非离子表面活性剂可选自由下列组成的组:葡萄糖酰胺、烷基多葡糖苷、蔗糖椰油酸酯、蔗糖月桂酸酯、链烷醇酰胺、乙氧基化醇、以及它们的混合物。在一个实施方案中,非离子表面活性剂选自由下列组成的组:一羟基硬脂酸甘油酯、异硬脂基聚氧乙烯醚-2、十三烷基聚氧乙烯醚-3、羟基硬脂酸、硬脂酸丙二醇酯、PEG-2硬脂酸酯、一硬脂酸脱水山梨醇酯、月桂酸甘油酯、月桂基聚氧乙烯醚-2、椰油酰胺单乙醇胺、月桂酰胺单乙醇胺、以及它们的混合物。
在特定实施方案中,所述辅助表面活性剂选自由下列组成的组:椰油基单乙醇酰胺、椰油酰氨基丙基甜菜碱、月桂酰氨基丙基甜菜碱、椰油基甜菜碱、月桂基甜菜碱、月桂基氧化胺、月桂基两性乙酸钠;烷基甘油基醚、烷基二甘油基醚、1,2-烷基环状亚硫酸酯、1,2-烷基环状碳酸酯、1,2-烷基环氧化物、烷基缩水甘油基醚和烷基-1,3-二氧戊环,其中烷基包含6至14个直链或支链构型的碳原子;1,2-链烷二醇(其中总碳量为6至14个直链或支链碳原子)、甲基-2-羟基癸基醚、羟乙基-2-十二烷基醚、羟乙基-2-癸基醚、以及它们的混合物。
阳离子表面活性剂可衍生自在制剂pH下质子化的胺,例如二羟基乙基月桂胺、月桂基二甲胺、月桂酰二甲基酰胺基丙胺、椰油基酰胺基丙胺等等。阳离子表面活性剂还可衍生自脂族季铵盐,如月桂基三甲基氯化铵和月桂酰胺基丙基三甲基氯化铵。
调理剂
水相可包含调理剂,并且在一些实施方案中包含按所述清洁组合物的重量计至少约0.05重量%的调理剂。在特定实施方案中,所述清洁组合物包含按所述清洁组合物的重量计约0.05重量%至约10重量%的调理剂,并且在其它实施方案中包含按所述清洁组合物的重量计约0.05重量%至约2重量%的调理剂,在可供选择的实施方案中包含按所述清洁组合物的重量计约0.5重量%至约10重量%的调理剂,并且在其它实施方案中包含按所述清洁组合物的重量计约0.5重量%至约6重量%的调理剂。
调理剂可包括例如大颗粒和小颗粒硅氧烷(例如小于0.1微米的小颗粒硅氧烷)和油。
硅氧烷
清洁组合物中的调理剂通常为不溶解的、非挥发性的硅氧烷调理剂。硅氧烷调理剂颗粒可包括挥发性硅氧烷、非挥发性硅氧烷、或它们的组合。硅氧烷调理剂颗粒可包括硅氧烷流体调理剂,并且还可以包含其它成分如硅氧烷树脂,以改善硅氧烷流体的沉积功效。专业技术人员将认识到,通过改变流量比,改变输入到本发明高剪切装置中的能量,或作为另外一种选择,通过控制层状表面活性剂稀释完成后的混合能量,可控制最终组合物中硅氧烷(粒度直径为约0.005μm至约50μm)或其它不能与水混溶的液体的粒度。
适宜硅氧烷调理剂和硅氧烷的任选悬浮剂的非限制性实例描述于美国重新公布的专利No.34,584、U.S.5,104,646和U.S.5,106,609中。在25℃下测定,可用于本专利申请组合物中的硅氧烷调理剂一般具有约20至约2,000,000厘沲(“csk”),典型约1,000至约1,800,000csk,通常约50,000至约1,500,000csk,典型约100,000至约1,500,000csk的粘度。
任选成分
去头皮屑活性物质-所述水相还可包含去头皮屑剂。适宜去头皮屑颗粒的非限制性实例包括:吡啶硫酮盐、含锌层状物质、唑(如酮康唑、益康唑和二氯苯基咪唑二氧杂环戊烷)、硫化硒、粒状硫、水杨酸、以及它们的混合物。典型的去头皮屑颗粒为吡啶硫酮盐。此类去头皮屑颗粒应该在物理和化学上与组合物的组分相容,并且不应该不适当地破坏产品的稳定性、美观性或性能。
其它抗微生物活性物质可存在于水相中,并且可包括白千层树(茶树)和木炭的提取物。本专利申请还可包含抗微生物活性物质的组合。此类组合可包括羟甲辛吡酮和1-氧-2-巯基吡啶锌的组合、松焦油和硫的组合、水杨酸和1-氧-2-巯基吡啶锌的组合、二氯苯基咪唑二氧戊环和1-氧-2-巯基吡啶锌的组合、二氯苯基咪唑二氧戊环和水杨酸的组合、羟甲辛吡酮和氯咪巴唑的组合和水杨酸和羟甲辛吡酮的组合、以及它们的混合物。
此外,可存在于水相中的附加组分可包括糖胺(例如N-乙酰基葡糖胺)、维生素B3化合物、脱氢乙酸钠、脱氢乙酸及其盐、植物甾醇、大豆衍生物(例如雌马酚和其它异黄酮)、烟酰胺、植烷三醇、金合欢醇、红没药醇、水杨酸化合物、去氧苯比妥、二烷酰基羟脯氨酸化合物、N-酰基氨基酸化合物、类视色素(例如丙酸视黄酯)、水溶性维生素、抗坏血酸盐(例如维生素C、抗坏血酸、抗坏血酸葡糖苷、抗坏血酸棕榈酸酯、抗坏血酸磷酸镁、抗坏血酸磷酸钠)、颗粒物质、防晒活性物质、丁基化羟基甲苯、丁基化羟基苯甲醚、它们的衍生物、以及它们的组合、染料、非挥发性溶剂或稀释剂(水溶性和水不溶性的)、珠光助剂、促泡剂、灭虱药、pH调节剂、香料、颗粒(例如有机的、无机的)、防腐剂、螯合剂、螯合试剂、蛋白质、紫外线吸收剂、颜料、其它氨基酸和其它维生素。
例如,本专利申请的水相可包含一种或多种维生素和/或氨基酸,如:水溶性维生素如维生素B1、B2、B6、B12、C、泛酸、泛基乙基醚、泛醇、生物素、以及它们的衍生物,水溶性氨基酸如天冬酰胺、丙氨酸、谷氨酸、以及它们的盐,水不溶性维生素如维生素A、D、E、以及它们的衍生物,水不溶性氨基酸如酪氨酸、色氨酸、以及它们的盐。
此外,所述组合物还可以包含其它肽,如2002年12月10日公布的授予Robinson等人的U.S.6,492,326中所公开的那些(例如五肽,如lys-thr-thr-lys-ser、以及它们的衍生物)。适宜的五肽衍生物包括购自Sederma,France的棕榈酰-lys-thr-thr-lys-ser。另一种可用于本文组合物中的任选二肽为肌肽。本文所用术语“肽”足够广泛,以能够包括一种或多种肽、一种或多种肽衍生物、以及它们的组合。
任何适宜的其它任选组分也可包含于本专利申请的个人护理组合物中,如常规用于指定产品类型中的那些成分。CTFA Cosmetic IngredientHandbook,第十版(由Cosmetic,Toiletry,and Fragrance Association,Inc.,Washington,D.C.公布)(2004)(下文称为“CTFA”)描述了各种各样可加入到本文组合物中的非限制性物质。
实施例
下列实施例示出了本发明。所期望的清洁组合物如下所示:
表1
*一些聚合物,尤其是具有高价阳离子那些,在与表面活性剂接触之前优选地在水中水合。就本发明实施例而言,我们保守地假定聚合物在加入到组合物中之前无需预先水合。
1 得自Stepan Matamoros(MX)
2 得自Stepan Matamoros(MX)
3 得自Rhodia Vernon(TX)
表2
*一些聚合物,尤其是具有高价阳离子那些,在与表面活性剂接触之前优选地在水中水合。就本发明实施例而言,我们保守地假定聚合物在加入到组合物中之前无需预先水合。
1 得自Stepan Matamoros(MX)
2 得自Stepan Matamoros(MX)
3 得自Rhodia Vernon(TX)
在常规加工中,月桂基聚氧乙烯醚-1硫酸钠(SLE1S)将以预先稀释的25%活性物质形式加入,或就地稀释至~25%活性物质,然后加入其它成分。(如果使用高活性形式的SLE3S或SLE1S/SLE3S共混物,而不是SLE1S物质,则分析相类似)。然而,由上表1显而易见,该方法需要在制备后从制剂中除水(8.11重量%),这在工业规模上显然是不可取的。此外,没有水可用于优选的聚合物和防腐剂固体预分散体。相反,如果使用本发明方法,有大量的可用的水(23.78%),并且在加入层状70%SLE1S之前,在低粘度环境中快速发生若干加入。
为将70%SLE1S稀释至25%,上述体系的MFR不是简单的1.8比率。为例证目的,除了70%SLE1S和芳香剂以外,在加入SLE1S前,所有成分将视为水相的一部分,就优选的物流操作而言,保留芳香剂稍后加入。在具有简单的顶置式混合器的100kg槽罐中,将适当比率/量的瓜尔胶羟丙基三甲基铵、乙二胺四乙酸二钠、苯甲酸钠、椰油酰氨基丙基甜菜碱和SLE3S按顺序加入到水中。在环境温度(20-25℃)下混合30分钟后,用Moyno FB螺杆抽油泵将该水相以11.2kg/min的速率泵送至18元件、15mm直径的SMX静态混合器(Sulzer Chemtech,Switzerland)的三通上游。进行SMX三通上游的第二相为70%SLE1S,同样在环境温度(20-25℃)下自Waukesha 015U2凸叶转子泵以不同的流量泵送,以改变高剪切装置内的流量比。使离开混合器的所得组合物(见下表)静置一天,然后在25℃下,使用40mm的2度锥/板体系,在TA Instruments AR2000上进行流变测定。将1/sec的剪切速率施用2分钟,并且记录最后20秒的平均粘度作为最终粘度。
表3
由所述表显而易见,该组合物的MFR介于2.8和3.4之间,而所期望组合物规定的最大流量比为4.67,证明所述组合物可由本发明方法制得。在高剪切装置的槽罐下游,用1%芳香剂使表3第2行中的组合物完整,从而制得最终产品。
本文所公开的量纲和值不旨在被理解为严格地限于所述的精确值。相反,除非另外指明,每个这样的量纲均是指所引用数值和围绕那个数值的功能上等同的范围。例如,公开为“40mm”的量纲旨在表示“约40mm”。
除非明确排除或换句话讲有所限制,本文中引用的每一个文件,包括任何交叉引用或相关专利或专利申请,均据此以引用方式全文并入本文。对任何文献的引用均不是承认其为本文公开的或受权利要求书保护的任何发明的现有技术、或承认其独立地或以与任何其它一个或多个参考文献的任何组合的方式提出、建议或公开任何此类发明。此外,如果本文献中术语的任何含义或定义与任何以引用方式并入的文献中相同术语的任何含义或定义相冲突,将以本文献中赋予那个术语的含义或定义为准。
尽管举例说明和描述了本发明的特定实施方案,但是对本领域的技术人员显而易见的是,在不脱离本发明的实质和范围的情况下可作出许多其它的改变和变型。因此,所附权利要求旨在涵盖处于本发明范围内的所有这些改变和变型。
权利要求书(按照条约第19条的修改)
1.一种制备液体清洁组合物的方法,所述方法包括以下步骤:
-提供包含水和至少一种其它组分的水相,所述其它组分选自阴离子表面活性剂、两性表面活性剂、两性离子表面活性剂、非离子表面活性剂、调理聚合物、沉积聚合物和增稠聚合物;
-在层状相中提供表面活性剂,其中所述层状相包含所述层状相中的约50%至80%的一种或多种活性表面活性剂;
-在高剪切装置中按所述水相与层状相的流量比混合所述水相和所述层状相以获得如下液体清洁组合物,其中所述液体清洁组合物在1mm长度标度下是均匀的,并且在1/sec剪切速率具有小于100Pa-s的粘度。
2.如权利要求1所述的方法,其中所述高剪切装置内的所述水相在1/sec剪切速率的粘度为0.004至40Pa-s。
3.如权利要求1所述的方法,其中所述液体清洁组合物在1/sec剪切速率和25℃温度的粘度介于约2和约100Pa-s之间。
4.如权利要求1所述的方法,其中层状相中的所述表面活性剂为具有0.7至3.0个乙氧基部分每分子的月桂基聚氧乙烯醚硫酸钠或月桂基聚氧乙烯醚硫酸铵。
5.如权利要求1所述的方法,其中所述水相包含水和调理聚合物。
6.如权利要求1所述的方法,其中所述方法单程完成。
7.如权利要求1所述的方法,其中所述高剪切装置为动态(旋转)混合器,所述混合器内包含一个或多个高剪切区域,在至少一个区域内的最小尺寸为约0.1mm至约20mm。
8.如权利要求7所述的方法,其中所述动态混合器具有每秒5至50米的端速。
9.如权利要求1所述的方法,其中所述高剪切装置为静态混合器,所述静态混合器是指由所述材料流入所述装置中而自然引起其能量耗散的混合设备。
10.如权利要求9所述的方法,其中向通过所述装置的每单位流体赋予的能量为10-10,000J/kg。
11.如权利要求1所述的方法,其中所述方法还包括将至少一种剪切敏感性助剂加入到所述液体清洁组合物基料中的步骤。
Claims (11)
1.一种制备液体清洁组合物的方法,所述方法包括以下步骤:
-提供包含水和至少一种其它组分的水相,所述其它组分选自阴离子表面活性剂、两性表面活性剂、两性离子表面活性剂、非离子表面活性剂、调理聚合物、沉积聚合物和增稠聚合物;
-在层状相中提供表面活性剂,其中所述层状相包含所述层状相中约50%至80%的一种或多种活性表面活性剂;
-在高剪切装置中按所述水相与层状相的流量比混合所述水相和所述层状相以获得如下液体清洁组合物,其中所述液体清洁组合物在1mm长度标度下是均匀的,并且在1/sec剪切速率下具有小于100Pa-s的粘度。
2.如权利要求1所述的方法,其中所述高剪切装置内的所述水相在1/sec剪切速率下的粘度为0.004至40Pa-s。
3.如权利要求1所述的方法,其中所述液体清洁组合物在1/sec剪切速率和25℃温度的粘度介于约2和约100Pa-s之间。
4.如权利要求1所述的方法,其中层状相中的所述表面活性剂为具有0.7至3.0个乙氧基部分每分子的月桂基聚氧乙烯醚硫酸钠或月桂基聚氧乙烯醚硫酸铵。
5.如权利要求1所述的方法,其中所述水相包含水和调理聚合物。
6.如权利要求1所述的方法,其中所述方法单程完成。
7.如权利要求1所述的体系,其中所述高剪切装置为动态(旋转)混合器,所述混合器内包含一个或多个高剪切区域,在至少一个区域内的最小尺寸为约0.1mm至约20mm。
8.如权利要求7所述的体系,其中所述动态混合器具有每秒5至50米的端速。
9.如权利要求1所述的体系,其中所述高剪切装置为静态混合器,所述静态混合器是指由所述材料流入所述装置中而自然引起其能量耗散的混合设备。
10.如权利要求9所述的体系,其中向通过所述装置的每单位流体赋予的能量为10-10,000J/kg。
11.如权利要求1所述的方法,其中所述方法还包括将至少一种剪切敏感性助剂加入到所述液体清洁组合物基料中的步骤。
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Also Published As
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US20110053826A1 (en) | 2011-03-03 |
AU2010258967A1 (en) | 2012-01-12 |
MX2011013220A (es) | 2012-01-20 |
ES2409893T3 (es) | 2013-06-28 |
WO2010144397A1 (en) | 2010-12-16 |
JP2012528241A (ja) | 2012-11-12 |
CA2763774A1 (en) | 2010-12-16 |
EP2440646A1 (en) | 2012-04-18 |
US8440605B2 (en) | 2013-05-14 |
JP5540082B2 (ja) | 2014-07-02 |
EP2440646B1 (en) | 2013-03-06 |
CN102459554B (zh) | 2014-12-10 |
BRPI1010590A2 (pt) | 2016-03-15 |
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