CN102268094A - 被修饰的转铁蛋白抗体的融合蛋白 - Google Patents

被修饰的转铁蛋白抗体的融合蛋白 Download PDF

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CN102268094A
CN102268094A CN201110175090A CN201110175090A CN102268094A CN 102268094 A CN102268094 A CN 102268094A CN 201110175090 A CN201110175090 A CN 201110175090A CN 201110175090 A CN201110175090 A CN 201110175090A CN 102268094 A CN102268094 A CN 102268094A
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fusion rotein
variable region
antibody variable
peptide
antibody
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Chinese (zh)
Inventor
霍马扬.萨德吉
克里斯托弗.P.普里奥尔
安德鲁.特纳
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Biorexis Pharmaceutical Corp
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Biorexis Pharmaceutical Corp
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Priority claimed from US10/384,060 external-priority patent/US20030226155A1/en
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Publication of CN102268094A publication Critical patent/CN102268094A/zh
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    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
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CN201110175090A 2002-08-30 2003-08-28 被修饰的转铁蛋白抗体的融合蛋白 Pending CN102268094A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40697702P 2002-08-30 2002-08-30
US60/406,977 2002-08-30
US10/384,060 US20030226155A1 (en) 2001-08-30 2003-03-10 Modified transferrin-antibody fusion proteins
US10/384,060 2003-03-10

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CN201110175090A Pending CN102268094A (zh) 2002-08-30 2003-08-28 被修饰的转铁蛋白抗体的融合蛋白
CNA038247453A Pending CN1694895A (zh) 2002-08-30 2003-08-28 被修饰的转铁蛋白抗体的融合蛋白
CNA038247399A Pending CN1713920A (zh) 2002-08-30 2003-08-28 被修饰的转铁蛋白融合蛋白

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CNA038247399A Pending CN1713920A (zh) 2002-08-30 2003-08-28 被修饰的转铁蛋白融合蛋白

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US (1) US20060130158A1 (cg-RX-API-DMAC7.html)
EP (1) EP1545595B1 (cg-RX-API-DMAC7.html)
JP (1) JP4873860B2 (cg-RX-API-DMAC7.html)
CN (3) CN102268094A (cg-RX-API-DMAC7.html)
AT (1) ATE473011T1 (cg-RX-API-DMAC7.html)
AU (2) AU2003262886A1 (cg-RX-API-DMAC7.html)
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Cited By (8)

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CN106967171A (zh) * 2017-02-23 2017-07-21 郑州大学 一种全人源重组CD40L单抗Fab片段及其制备方法
CN109180819A (zh) * 2018-09-14 2019-01-11 苏州康宇生物科技有限公司 一种胰岛素衍生物的制备方法
CN111948388A (zh) * 2020-08-18 2020-11-17 山东农业大学 一种检测腐败梭菌的胶体金试纸条及其制备方法和应用
CN112312922A (zh) * 2018-06-21 2021-02-02 诺和诺德股份有限公司 用于治疗肥胖症的新型化合物
CN113267631A (zh) * 2021-05-17 2021-08-17 江苏普若维生物技术有限责任公司 一种检测TNF-α的电化学试剂盒制备方法
CN115135771A (zh) * 2019-10-25 2022-09-30 西北大学 用于富集膜泡和增加糖蛋白产量的无细胞提取物制备方案
WO2023142109A1 (zh) * 2022-01-30 2023-08-03 领诺(上海)医药科技有限公司 一种长效重组人生长激素及其应用
CN118931931A (zh) * 2024-07-23 2024-11-12 中国农业科学院北京畜牧兽医研究所 一种产气荚膜梭菌epsilon毒素-铁蛋白纳米颗粒抗原的制备方法

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US20070031440A1 (en) * 2001-08-30 2007-02-08 Prior Christopher P Modified transferin-antibody fusion proteins
US8129504B2 (en) 2001-08-30 2012-03-06 Biorexis Technology, Inc. Oral delivery of modified transferrin fusion proteins
CN1628126A (zh) * 2001-08-30 2005-06-15 比奥雷克西斯药物公司 经修饰的运铁蛋白融合蛋白
US7176278B2 (en) * 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US20030226155A1 (en) * 2001-08-30 2003-12-04 Biorexis Pharmaceutical Corporation Modified transferrin-antibody fusion proteins
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2007512001A (ja) * 2003-08-28 2007-05-17 バイオレクシス ファーマシューティカル コーポレイション Ｅｐｏミメティックペプチドおよび融合タンパク質
US20060205037A1 (en) * 2003-08-28 2006-09-14 Homayoun Sadeghi Modified transferrin fusion proteins
EA200700391A1 (ru) * 2004-08-03 2007-10-26 Байорексис Текнолоджи, Инк. Комбинированное лечение с применением слитых белков трансферрина, содержащих glp-1
US20090275481A1 (en) * 2005-06-17 2009-11-05 Pfizer, Inc. Anchored Transferrin Fusion Protein Libraries
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
EP2463295A1 (en) * 2006-05-22 2012-06-13 The Regents of The University of California Compositions and methods for the delivery of oxygen
CN101088502B (zh) * 2006-06-16 2012-11-21 中国科学院化学研究所 一种含有转铁蛋白和槲皮素的结合物的混合溶液及其用途
CA2657277C (en) 2006-07-13 2015-11-24 Upperton Limited Process for preparing particles of proteinaceous material
DK2046826T3 (da) * 2006-07-24 2011-10-24 Biorexis Pharmaceutical Corp Exendin-fusionsproteiner
CN101578373A (zh) * 2006-09-06 2009-11-11 费斯生物制药公司 融合肽治疗组合物
EP2114999A2 (en) 2006-12-12 2009-11-11 Biorexis Pharmaceutical Corporation Transferrin fusion protein libraries
CN105727261A (zh) 2008-06-27 2016-07-06 杜克大学 包含弹性蛋白样肽的治疗剂
US9034341B2 (en) * 2009-04-20 2015-05-19 Transtech Pharma, Llc Control of RAGE fusion protein glycosylation and RAGE fusion protein compositions
AU2010306940A1 (en) 2009-10-12 2012-06-07 Smith, Larry Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
US9644197B2 (en) * 2010-06-04 2017-05-09 Sk Chemicals Co., Ltd. Fusion protein having factor VII activity
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