CN102246081B - 扫描显微镜 - Google Patents

扫描显微镜 Download PDF

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Publication number
CN102246081B
CN102246081B CN200980150194.0A CN200980150194A CN102246081B CN 102246081 B CN102246081 B CN 102246081B CN 200980150194 A CN200980150194 A CN 200980150194A CN 102246081 B CN102246081 B CN 102246081B
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CN
China
Prior art keywords
flying
sample
controller
spot
optical sensor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN200980150194.0A
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English (en)
Chinese (zh)
Other versions
CN102246081A (zh
Inventor
E·范戴克
B·胡什肯
C·赫齐芒斯
H·韦伯恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
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Publication date
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Publication of CN102246081A publication Critical patent/CN102246081A/zh
Application granted granted Critical
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Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D5/00—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable
    • G01D5/26—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light
    • G01D5/32—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light with attenuation or whole or partial obturation of beams of light
    • G01D5/34—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells
    • G01D5/347—Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable characterised by optical transfer means, i.e. using infrared, visible, or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells using displacement encoding scales
    • G01D5/34746—Linear encoders
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2205/00—Indexing scheme relating to details of means for transferring or converting the output of a sensing member
    • G01D2205/90—Two-dimensional encoders, i.e. having one or two codes extending in two directions

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Length Measuring Devices By Optical Means (AREA)
CN200980150194.0A 2008-12-15 2009-12-10 扫描显微镜 Active CN102246081B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08305943.6 2008-12-15
EP08305943 2008-12-15
PCT/IB2009/055659 WO2010070553A1 (en) 2008-12-15 2009-12-10 Scanning microscope.

Publications (2)

Publication Number Publication Date
CN102246081A CN102246081A (zh) 2011-11-16
CN102246081B true CN102246081B (zh) 2015-06-03

Family

ID=41615824

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980150194.0A Active CN102246081B (zh) 2008-12-15 2009-12-10 扫描显微镜

Country Status (6)

Country Link
US (1) US9684159B2 (https=)
EP (1) EP2376965B1 (https=)
JP (1) JP5722787B2 (https=)
CN (1) CN102246081B (https=)
BR (1) BRPI0917740A2 (https=)
WO (1) WO2010070553A1 (https=)

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US9488823B2 (en) * 2012-06-07 2016-11-08 Complete Genomics, Inc. Techniques for scanned illumination
US9628676B2 (en) * 2012-06-07 2017-04-18 Complete Genomics, Inc. Imaging systems with movable scan mirrors
CN106770690B (zh) * 2016-12-16 2023-05-16 贵州航天计量测试技术研究所 一种超声扫描显微镜成像分辨力特性校准装置及校准方法
EP3589998B1 (en) * 2017-03-03 2023-08-23 Apton Biosystems, Inc. High speed scanning system with acceleration tracking
JP7119085B2 (ja) * 2017-11-30 2022-08-16 ライカ バイオシステムズ イメージング インコーポレイテッド 衝撃再走査システム
DE102020108514A1 (de) * 2019-03-28 2020-10-01 Carl Zeiss Microscopy Gmbh Verfahren zum Bestimmen eines Bildaufnahmefehlers
DE102020111786B4 (de) * 2020-04-30 2023-08-31 Till I.D. Gmbh Verfahren und Mikroskopvorrichtung für die beschleunigte Mikroskopie großer Proben sowie Datenträger
CN115265624B (zh) * 2022-08-12 2024-08-16 上海乂义实业有限公司 曲面探测器微扫超分辨系统

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US20080095467A1 (en) * 2001-03-19 2008-04-24 Dmetrix, Inc. Large-area imaging by concatenation with array microscope

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US20080095467A1 (en) * 2001-03-19 2008-04-24 Dmetrix, Inc. Large-area imaging by concatenation with array microscope
US6958819B1 (en) * 2002-04-04 2005-10-25 Nanometrics Incorporated Encoder with an alignment target
US20050163398A1 (en) * 2003-05-13 2005-07-28 Olympus Corporation Image processing apparatus
DE102005018896A1 (de) * 2005-04-22 2006-10-26 Leica Microsystems Cms Gmbh Verfahren zur Bestimmung des Lateralversatzes eines XYZ-Tisches

Also Published As

Publication number Publication date
BRPI0917740A2 (pt) 2016-02-16
WO2010070553A1 (en) 2010-06-24
US9684159B2 (en) 2017-06-20
EP2376965A1 (en) 2011-10-19
JP5722787B2 (ja) 2015-05-27
CN102246081A (zh) 2011-11-16
EP2376965B1 (en) 2020-11-11
US20110292200A1 (en) 2011-12-01
JP2012512426A (ja) 2012-05-31

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