CN102203123A - 在宿主细胞中制造糖基化蛋白的新方法 - Google Patents
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Cited By (8)
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| CN102586316A (zh) * | 2012-02-16 | 2012-07-18 | 中国科学院微生物研究所 | 人源糖基化改造的汉逊酵母 |
| CN102839157A (zh) * | 2012-07-12 | 2012-12-26 | 扬州大学 | 稳定共表达hST3GalIV和β1-4GalT1的MDCK细胞系及构建方法和应用 |
| CN104784754A (zh) * | 2015-03-04 | 2015-07-22 | 重庆市畜牧科学院 | 一种蚕丝人工血管及制备方法 |
| CN105372214A (zh) * | 2014-08-18 | 2016-03-02 | 中国科学院上海有机化学研究所 | 一种鉴定新红细胞生成刺激蛋白的n-连接寡糖结构的方法 |
| CN106867966A (zh) * | 2015-12-11 | 2017-06-20 | 复旦大学 | 稳定表达核心α(1,3)岩藻糖基转移酶的脊椎动物细胞系及其制备方法 |
| CN108179160A (zh) * | 2018-01-29 | 2018-06-19 | 江南大学 | 一种植烷醇连接的高甘露糖型寡糖的制备方法 |
| CN110687035A (zh) * | 2019-10-10 | 2020-01-14 | 沈阳万类生物科技有限公司 | Annexin V-Light 650凋亡检测试剂盒 |
| CN112074608A (zh) * | 2018-05-01 | 2020-12-11 | 科纳根公司 | 用于产生具有高聚糖占有率的糖分子的重组生物体和方法 |
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| KR100787073B1 (ko) * | 2000-06-28 | 2007-12-21 | 글리코파이, 인크. | 변형된 당단백질의 제조방법 |
| CN102858949B (zh) | 2010-02-24 | 2016-07-06 | 默沙东公司 | 用于增加在巴氏毕赤酵母中生产的治疗性糖蛋白上的n-糖基化位点占据的方法 |
| RU2013128619A (ru) * | 2010-11-24 | 2014-12-27 | Новартис Интернэшнл Фармасьютикал Лтд. | Слитные ферменты |
| WO2013123034A1 (en) * | 2012-02-16 | 2013-08-22 | Merck Sharp & Dohme Corp. | Methods for reducing mannosyltransferase activity in yeast |
| JP6356229B2 (ja) * | 2013-06-04 | 2018-07-11 | アイコン ジェネティクス ゲーエムベーハー | 植物産生糖タンパク質及び組換え糖タンパク質のｎ−グリコシル化部位占有率を調節する方法 |
| PL3019621T3 (pl) * | 2013-07-10 | 2019-05-31 | Glykos Finland Oy | Wytwarzanie glikoprotein o zwiększonym zajmowaniu miejsca N-glikozylacji |
| BR112016017606A2 (pt) * | 2014-01-29 | 2017-10-10 | Amgen Inc | superexpressão de reguladores de via de n-glicosilação para modular a glicosilação de proteínas recombinantes |
| CA2954974A1 (en) | 2014-07-21 | 2016-01-28 | Glykos Finland Oy | Production of glycoproteins with mammalian-like n-glycans in filamentous fungi |
| JP6757341B2 (ja) * | 2018-01-26 | 2020-09-16 | 東洋紡株式会社 | アスペルギルス属微生物が生産するタンパク質のｎ型糖鎖構造を改変する方法 |
| CN117377752A (zh) * | 2021-03-11 | 2024-01-09 | 二进国际(美国)有限公司 | 用于生产具有减少的或不含n-连接的糖基化的外源蛋白的遗传修饰的丝状真菌 |
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| US7507573B2 (en) * | 2003-11-14 | 2009-03-24 | Vib, Vzw | Modification of protein glycosylation in methylotrophic yeast |
| CA2573745A1 (en) * | 2004-07-21 | 2007-01-12 | Glycofi, Inc. | Immunoglobulins comprising predominantly a glcnac2man3glcnac2 glycoform |
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- 2009-10-31 WO PCT/EP2009/007816 patent/WO2010049177A1/en not_active Ceased
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102586316A (zh) * | 2012-02-16 | 2012-07-18 | 中国科学院微生物研究所 | 人源糖基化改造的汉逊酵母 |
| CN102839157A (zh) * | 2012-07-12 | 2012-12-26 | 扬州大学 | 稳定共表达hST3GalIV和β1-4GalT1的MDCK细胞系及构建方法和应用 |
| CN105372214A (zh) * | 2014-08-18 | 2016-03-02 | 中国科学院上海有机化学研究所 | 一种鉴定新红细胞生成刺激蛋白的n-连接寡糖结构的方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2350123A1 (en) | 2011-08-03 |
| WO2010049177A1 (en) | 2010-05-06 |
| US20110207214A1 (en) | 2011-08-25 |
| JP2012506710A (ja) | 2012-03-22 |
| TW201028431A (en) | 2010-08-01 |
| AU2009309925A1 (en) | 2010-05-06 |
| IL212580A0 (en) | 2011-07-31 |
| CA2741964A1 (en) | 2010-05-06 |
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