CN102131809A - 三环吡唑并吡啶激酶抑制剂 - Google Patents
三环吡唑并吡啶激酶抑制剂 Download PDFInfo
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- CN102131809A CN102131809A CN2009801327408A CN200980132740A CN102131809A CN 102131809 A CN102131809 A CN 102131809A CN 2009801327408 A CN2009801327408 A CN 2009801327408A CN 200980132740 A CN200980132740 A CN 200980132740A CN 102131809 A CN102131809 A CN 102131809A
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Classifications
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
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- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
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- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8292408P | 2008-07-23 | 2008-07-23 | |
| US61/082,924 | 2008-07-23 | ||
| PCT/US2009/051430 WO2010011768A1 (en) | 2008-07-23 | 2009-07-22 | Tri-cyclic pyrazolopyridine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102131809A true CN102131809A (zh) | 2011-07-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN2009801327408A Pending CN102131809A (zh) | 2008-07-23 | 2009-07-22 | 三环吡唑并吡啶激酶抑制剂 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8563576B2 (https=) |
| EP (1) | EP2328896B1 (https=) |
| JP (2) | JP5631310B2 (https=) |
| CN (1) | CN102131809A (https=) |
| AU (1) | AU2009274023A1 (https=) |
| CA (1) | CA2731498A1 (https=) |
| MX (1) | MX2011000837A (https=) |
| WO (1) | WO2010011768A1 (https=) |
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| US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
| MX2011001319A (es) * | 2008-08-06 | 2011-04-05 | Vertex Pharma | Inhibidores de aminopiridina cinasa. |
| RS57869B1 (sr) | 2009-06-17 | 2018-12-31 | Vertex Pharma | Inhibitori replikacije virusa gripa |
| MX2012008643A (es) * | 2010-01-27 | 2013-02-26 | Vertex Pharma | Inhibidores de cinasas de pirazolopiridinas. |
| EP2528917B1 (en) * | 2010-01-27 | 2016-10-19 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridines useful for the treatment of autoimmune, inflammatory or (hyper)proliferative diseases |
| JP2013518112A (ja) * | 2010-01-27 | 2013-05-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラゾロピリジンキナーゼ阻害剤 |
| AU2011343642A1 (en) | 2010-12-16 | 2013-05-02 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| MX2013006840A (es) | 2010-12-16 | 2014-01-31 | Vertex Pharma | Inhibidores de la replicacion de los virus de la influenza. |
| CN103492382A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| EP2858984A1 (en) | 2012-06-08 | 2015-04-15 | Vertex Pharmaceuticals Inc. | Inhibitors of influenza viruses replication |
| EP3046560B1 (en) | 2013-09-18 | 2021-01-06 | EpiAxis Therapeutics Pty Ltd | Stem cell modulation ii |
| RS59144B1 (sr) | 2013-11-13 | 2019-09-30 | Vertex Pharma | Inhibitori replikacije virusa influence |
| HRP20181272T1 (hr) | 2013-11-13 | 2018-10-05 | Vertex Pharmaceuticals Incorporated | Postupci priprave inhibitora replikacije virusa influence |
| CA2958704A1 (en) | 2014-08-25 | 2016-03-03 | University Of Canberra | Compositions for modulating cancer stem cells and uses therefor |
| WO2016037106A1 (en) | 2014-09-05 | 2016-03-10 | Allosteros Therapeutics, Inc | CaMKII INHIBITORS AND USES THEREOF |
| JP2018509389A (ja) * | 2015-01-30 | 2018-04-05 | リ・ガリ・ベスローテン・フエンノートシャップＬｉ Ｇａｌｌｉ Ｂ．Ｖ． | 膣用薬物送達デバイス |
| JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤 |
| JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤を調製する方法 |
| KR102494647B1 (ko) | 2016-07-14 | 2023-01-31 | 브리스톨-마이어스 스큅 컴퍼니 | 비시클릭 헤테로아릴 치환된 화합물 |
| CN109689664B (zh) | 2016-07-14 | 2022-04-15 | 百时美施贵宝公司 | 作为par4抑制剂的三环杂芳基取代的喹啉和氮杂喹啉化合物 |
| US20190292176A1 (en) | 2016-07-14 | 2019-09-26 | Bistol-Myers Squibb Company | Bicyclic heteroaryl substituted compounds |
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-
2009
- 2009-07-22 AU AU2009274023A patent/AU2009274023A1/en not_active Abandoned
- 2009-07-22 CN CN2009801327408A patent/CN102131809A/zh active Pending
- 2009-07-22 EP EP09790733.1A patent/EP2328896B1/en not_active Not-in-force
- 2009-07-22 JP JP2011520173A patent/JP5631310B2/ja not_active Expired - Fee Related
- 2009-07-22 WO PCT/US2009/051430 patent/WO2010011768A1/en not_active Ceased
- 2009-07-22 CA CA2731498A patent/CA2731498A1/en not_active Abandoned
- 2009-07-22 MX MX2011000837A patent/MX2011000837A/es not_active Application Discontinuation
-
2011
- 2011-12-01 US US13/308,612 patent/US8563576B2/en not_active Expired - Fee Related
-
2014
- 2014-08-08 JP JP2014162132A patent/JP2014208708A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014208708A (ja) | 2014-11-06 |
| MX2011000837A (es) | 2011-04-05 |
| US20120184534A1 (en) | 2012-07-19 |
| AU2009274023A1 (en) | 2010-01-28 |
| CA2731498A1 (en) | 2010-01-28 |
| EP2328896A1 (en) | 2011-06-08 |
| JP2011529065A (ja) | 2011-12-01 |
| WO2010011768A1 (en) | 2010-01-28 |
| JP5631310B2 (ja) | 2014-11-26 |
| EP2328896B1 (en) | 2013-10-23 |
| US8563576B2 (en) | 2013-10-22 |
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