CN102000005B

CN102000005B - Oral care solution

Info

Publication number: CN102000005B
Application number: CN 201010563459
Authority: CN
Inventors: 许荧
Original assignee: TIANJIN JING SHUO SCIENCE AND TRADE CO Ltd
Current assignee: Tianjin top pharmaceutical Limited by Share Ltd
Priority date: 2010-11-27
Filing date: 2010-11-27
Publication date: 2013-03-27
Anticipated expiration: 2030-11-27
Also published as: CN102000005A

Abstract

The invention relates to an oral care solution which comprises the following materials in percentage by weight: 1-20% of medicinal plant extract, 0.005-0.5% of sodium azulene sulfonate, 0.1-10% of active component, 0.01-0.5% of antibacterial agent, 1-15% of solubilizer, 0.01-5% of sweetening agent, 1-20% of thickening agent, 0.01-0.5% of perfume, 0.1-5% of ethanol, 13-90% of water and 0.001-10% of pH regulator. The oral care solution contains the medicinal plant extract of good mouthfeel acceptability and the active component protecting the mucosa, has natural and pure mouthfeel and is applicable to oral discomfort and daily oral care. The invention has the effects of cleaning oral cavity and teeth, relieving symptoms such as toothache, gum bleeding, oral ulcer, gingivitis, periodontitis, sore throat and the like and protecting oral health.

Description

Oral nursing liquid

Technical field

The present invention relates to a kind of oral nursing liquid.Particularly relate to a kind of suitable old man, child or suffer from that specific crowd that oral disease is not suitable for brushing teeth uses; can not use at daily health caring or oral cavity in good time; can effectively alleviate the multiple malaise symptoms in oral cavity, the oral nursing liquid of general protection tooth and oral health.

Background technology

In daily life, people still are accustomed to toothpaste cleaning teeth and oral cavity, but some specific crowds or specific occasion are always arranged, do not have for various reasons conditioned disjunction not brush teeth with toothpaste, as: with after the meal, see the client before, before and after the tooth treatment, or the old people of loss of tooth, the child that can not brush teeth etc.In this case, selecting collutory or oral nursing liquid to be in harmony ought be only again.

At present, the collutory of selling on the market has cleaning, the counteract oral malodour effect.Also have some oral nursing liquids to have the effect that eliminates dental plaque, and the effect of killing oral cavity bacterium.But, no matter be the collutory oral nursing liquid, although the oral cavity is all had certain nursing role, but most of user strange taste in its process of gargling of endurable all, especially the child is difficult to adapt to especially.

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of oral cavity that both had been fit to not use the daily mouth care that also suits, the oral nursing liquid of the health in protection oral cavity in good time.

The technical solution adopted in the present invention is: a kind of oral nursing liquid, comprise by weight: medicinal plant extract 1%-20%, Sodium Azulenesulfonate 0.005-0.5%, functional component 0.1%-10%, antibacterial 0.01%-0.5%, solubilizing agent 1-15%, sweeting agent 0.01%-5%, thickening agent 1-20%, essence 0.01%-0.5%, ethanol 0.1%-5%, water 13%-90%, pH value regulator 0.001%-10%, wherein, described medicinal plant extract is Flos Lonicerae extract, Radix Scrophulariae extract, Herba Lophatheri extract, in green tea extract and the Herba Andrographis extract one or more, described functional component is sodium fluoride, in potassium chloride and the vitamin C one or more, described antibacterial is triclosan, a kind of in hibitane and the cetylpyridinium chloride, described thickening agent is one or both in glycerol and the propylene glycol.

Described solubilizing agent is one or both in PEG400 and the tertiary sodium phosphate.

Described sweeting agent is one or more in sorbitol, glucide and the stevioside.

Described essence is the L-Mentholum.

Described pH value regulator comprises: one or both in sodium bicarbonate and the sodium dihydrogen phosphate.

Oral nursing liquid of the present invention, composition comprise the functional component of the good medicinal plant extract of mouthfeel acceptance and protection mucosa, and mouthfeel is natural pure, both have been fit to the oral cavity and have not used in good time, also suitable daily mouth care.Have in effect: cleaning oral cavity and tooth, alleviate the malaise symptoms such as toothache, gingival hemorrhage, oral ulcer, gingivitis, periodontitis, laryngopharynx swelling and pain, the health in protection oral cavity.The present invention has following features:

1, Sodium Azulenesulfonate is allocated in the oral nursing liquid, can be protected gingiva, throat and oral mucosa, make the oral cavity more healthy.

2, the medicinal plant extract of choosing is allocated in the oral nursing liquid, except keeping the Sodium Azulenesulfonate original flavor, made the products taste that adds Mentholum better, can also relieving sore-throat by clearing away heat, the auxiliary protection oral health.

3, develop and Sodium Azulenesulfonate and medicinal plant extract and the molten solubilizing agent that is integrated of other composition can be joined oral nursing liquid the all-in-one-piece true solution, stable homogeneous strengthens commodity value.

The specific embodiment

Below in conjunction with embodiment and accompanying drawing oral nursing liquid of the present invention is made a detailed description.

Oral nursing liquid of the present invention is to comform multiple medicines with in the plant; go out nearly ten kinds except having the effects such as heat-clearing and toxic substances removing, pain easing and hemostasis, pharynx-clearing throat-benefiting through test and alternative; also will be without the medicinal plants of bad abnormal smells from the patient; with the extracts active ingredients of above-mentioned plant out, and it is formulated to be aided with functional component and the mouthfeel mediator agent of protecting the oral cavity.

Oral nursing liquid of the present invention comprises by weight: medicinal plant extract 1%-20%, Sodium Azulenesulfonate 0.005-0.5%, functional component 0.1%-10%, antibacterial 0.01%-0.5%, solubilizing agent 1-15%, sweeting agent 0.01%-5%, thickening agent 1-20%, essence 0.01%-0.5%, solvent 1%-90%, pH value mediator agent 0.001%-10%.

Wherein, described medicinal plant extract is one or more in Flos Lonicerae, Radix Scrophulariae, Herba Lophatheri, Radix Gentianae Macrophyllae, Flos Chrysanthemi, green tea, Herba Pileae Scriptae, Herba Andrographis and the Radix Scutellariae; Described functional component is one or more in fluoride, strontium chloride, strontium acetate, potassium chloride and the potassium nitrate; Described antibacterial is a kind of in triclosan, hibitane, benzethonium chloride and the cetylpyridinium chloride; Described solubilizing agent is one or both in Polyethylene Glycol and the tertiary sodium phosphate; Described sweeting agent is one or more in sorbitol, glucide, stevioside, xylitol, the aspartame; Described thickening agent is one or both in glycerol and the propylene glycol; Described essence is the L-Mentholum; Described solvent is one or both in the second alcohol and water; Described pH value mediator agent comprises: one or more in sodium bicarbonate, tertiary sodium phosphate and sodium dihydrogen phosphate or the potassium.

Embodiment one (take preparation 100kg as example)

Embodiment two (take preparation 100kg as example)

Embodiment three (take preparation 100kg as example)

Effect observation:

The crowd that choosing has a various oral cavities malaise symptoms is totally 260 examples, wherein take the oral ulcer symptom as main volunteers' 85 examples; Volunteers' 86 examples that gingival hemorrhage and positive gingival swelling and pain are arranged at ordinary times with readme, volunteers' 89 examples take laryngopharynx swelling and pain as the primary symptom shape, temporarily to be not suitable for brushing teeth and volunteers' 80 examples of halitosis arranged, these four groups of personnel used respectively the application's patented product 7 days, every day, observed result showed for several times:

Having in 85 examples of oral ulcer symptom has 78 routine feels pain obviously to alleviate, and ulcer surface is no longer rubescent, and effective percentage is 91.8%, and all the other personnel's feels pain slightly have and alleviate, and effect is not too obvious;

86 examples are had gingival hemorrhage and the symptom personnel that swell and ache, have 76 routine gingival hemorrhages to be improved, gingiva pain is improved clearly, and the sensation oral cavity is very comfortable in the use procedure, and effective percentage is 88.4%, and all the other 10 examples are improved DeGrain;

To the user of service of 89 routine laryngopharynx swelling and pain, there are 86 routine pain obviously to alleviate, feel pharyngeal nice and cool comfortable, effective percentage 96.6%, other 6 examples feel to improve DeGrain;

Brush teeth and have the volunteers of halitosis to observe temporarily being not suitable for, comfortable with rear 80 routine panesthesia oral cavities, the cleaning oral cavity successful, halitosis all has clear improvement, and effective percentage is 100%.

On the whole, the present invention to the oral ulcer, the gingival hemorrhage that occur at ordinary times, swell and ache, effect that laryngopharynx swelling and pain all has good relief of symptoms.Average effectiveness level is 92.3%; To oral cavity cleaning and to improve the halitosis effective percentage be 100%.

Claims

1. oral nursing liquid, it is characterized in that, comprise by weight: medicinal plant extract 1%-20%, Sodium Azulenesulfonate 0.005-0.5%, functional component 0.1%-10%, antibacterial 0.01%-0.5%, solubilizing agent 1-15%, sweeting agent 0.01%-5%, thickening agent 1-20%, essence 0.01%-0.5%, ethanol 0.1%-5%, water 13%-90%, pH value regulator 0.001%-10%, wherein, described medicinal plant extract is Flos Lonicerae extract, Radix Scrophulariae extract, Herba Lophatheri extract, in green tea extract and the Herba Andrographis extract one or more, described functional component is sodium fluoride, in potassium chloride and the vitamin C one or more, described antibacterial is triclosan, a kind of in hibitane and the cetylpyridinium chloride, described thickening agent is one or both in glycerol and the propylene glycol.

2. oral nursing liquid according to claim 1 is characterized in that, described solubilizing agent is one or both in PEG400 and the tertiary sodium phosphate.

3. oral nursing liquid according to claim 1 is characterized in that, described sweeting agent is one or more in sorbitol, glucide and the stevioside.

4. oral nursing liquid according to claim 1 is characterized in that, described essence is the L-Mentholum.

5. oral nursing liquid according to claim 1 is characterized in that, described pH value regulator comprises: one or both in sodium bicarbonate and the sodium dihydrogen phosphate.