CN113398205A - Anti-cancer oral care solution and preparation method thereof - Google Patents

Abstract

The invention provides an anticancer oral care solution and a preparation method thereof, and is characterized in that the oral care solution comprises: the plant extract comprises plant extract, sodium olsulfonate, an antibacterial agent, a solubilizer, a sweetener, a thickening agent, essence, ethanol, water and a ph regulator, wherein the plant extract is obtained by extracting the following plants in parts by weight: 6-10 parts of serissa serissoides, 8-15 parts of glossy privet fruit, 8-15 parts of ficus pumila, 6-10 parts of radix rehmanniae, 6-10 parts of radix scrophulariae, 8-15 parts of radix ophiopogonis, 6-10 parts of adenophora stricta, 8-15 parts of rhizoma anemarrhenae, 3-6 parts of glabrous sarcandra herb, 10-12 parts of cortex albiziae and 6-9 parts of negundo chastetree fruit; the lignan glycoside in the albizzia julibrissin bark and the vitexin in the vitex negundo linn have good anticancer effect, and can obviously inhibit oral cavity fibrosis.

Description

Anti-cancer oral care solution and preparation method thereof

Technical Field

The invention relates to the field of oral care, in particular to an anti-cancer oral care solution and a preparation method thereof.

Background

The large amount of chewing areca is one of the important causes of the fibrosis under the oral mucosa, the fibrosis under the oral mucosa is determined as a precancerous state by the world health organization, how to form a good oral hygiene habit in daily life becomes very important, and the oral care solution is used as a mode for maintaining the oral cavity, thereby playing a corresponding role in cleaning the oral cavity.

A number of oral care solutions have now been developed and, after extensive search and reference, it has been found that there are existing oral care solutions as disclosed in publication nos. US20120301209a1, JP5754711B2 and KR101454094B1, which comprise the following raw materials: water, ethanol, glycerin monostearate, xylitol, sorbitol, plant extract, magnesium lithium silicate and a bacteriostatic agent. The oral care solution disclosed by the invention researches the influence of different types of surfactants on antibacterial performance and treatment efficacy, and screens out proper surfactants and dosage. The oral cavity nursing liquid has low cost, safety and reliability, contains plant extracts with good taste acceptance and effective components for protecting teeth, has natural and pure taste, has obvious effects of killing bacteria in the oral cavity, reducing internal heat and diminishing inflammation, is suitable for not-in-time use of the oral cavity, is also suitable for daily oral cavity nursing, can effectively clean the oral cavity and the teeth, relieves uncomfortable symptoms such as toothache, gingival bleeding, oral ulcer, gingivitis, periodontitis, sore throat and the like, and protects the health of the oral cavity, but the oral cavity nursing liquid can only play a common protection effect and cannot inhibit oral cavity fibrosis and prevent oral cavity cancer.

Disclosure of Invention

The invention aims to provide an anti-cancer oral care solution aiming at the defects,

in order to overcome the defects of the prior art, the invention adopts the following technical scheme:

an anti-cancer oral care solution, comprising: the plant extract comprises plant extract, sodium olsulfonate, an antibacterial agent, a solubilizer, a sweetener, a thickening agent, essence, ethanol, water and a ph regulator, wherein the plant extract is obtained by extracting the following plants in parts by weight: 6-10 parts of serissa serissoides, 8-15 parts of glossy privet fruit, 8-15 parts of ficus pumila, 6-10 parts of radix rehmanniae, 6-10 parts of radix scrophulariae, 8-15 parts of radix ophiopogonis, 6-10 parts of adenophora stricta, 8-15 parts of rhizoma anemarrhenae, 3-6 parts of glabrous sarcandra herb, 10-12 parts of cortex albiziae and 6-9 parts of negundo chastetree fruit.

Further, the plant extract is obtained by extracting the following plants in parts by weight: 8 parts of serissa serissoides, 12 parts of glossy privet fruit, 10 parts of ficus microcarpa, 7 parts of radix rehmanniae, 9 parts of radix scrophulariae, 12 parts of radix ophiopogonis, 8 parts of adenophora stricta, 10 parts of rhizoma anemarrhenae, 6 parts of glabrous sarcandra herb, 10 parts of cortex albiziae and 8 parts of negundo chastetree fruit.

A process for preparing an anti-cancer oral care solution according to any preceding claim, comprising the steps of:

step 1, raw material pretreatment: cleaning and drying the medicinal raw materials of serissa serissoide, glossy privet fruit, ficus microcarpa leaf, radix rehmanniae, figwort root, dwarf lilyturf tuber, adenophora stricta, rhizoma anemarrhenae, glabrous sarcandra herb, cortex albiziae and negundo chastetree fruit respectively for later use;

step 2, batching: weighing the raw material medicaments according to the weight ratio, cutting or crushing the raw materials, and uniformly mixing the cut or crushed raw material medicaments;

step 3, extraction: adding 5-20 times of water or 50-70% ethanol into the uniformly mixed traditional Chinese medicines, extracting for 2-3 times, each time for 1-3 hours, controlling the temperature at 70-100 ℃, and filtering, mixing and filtering to obtain a plant extracting solution;

step 4, preparing liquid: and (2) putting 1L of water into a stirrer, heating to 80 ℃, adding 10ml of the plant extract obtained in the step (3) while stirring, then sequentially adding 1g of sodium olsulfon, 2g of antibacterial agent, 20g of solubilizer, 15g of sweetener, 30g of thickener and 10ml of ethanol, fully stirring for 30min, uniformly mixing, then adding 6g of essence and 9g of ph regulator, uniformly mixing, and concentrating to 500ml on a rotary evaporator to obtain the anticancer oral care solution.

The beneficial effects obtained by the invention are as follows:

by adding the extract of the silktree albizzia bark and the negundo chastetree fruit, the prepared oral care solution has the effects of inhibiting oral fibrosis and preventing oral cancer.

Drawings

The invention will be further understood from the following description in conjunction with the accompanying drawings. The components in the figures are not necessarily to scale, emphasis instead being placed upon illustrating the principles of the embodiments. Like reference numerals designate corresponding parts throughout the different views.

FIG. 1 is a data comparison table of clinical experiments according to the present invention.

FIG. 2 is a schematic flow chart of the preparation method of the present invention.

FIG. 3 is a schematic diagram of the structure of the shredder of the present invention.

Fig. 4 is a schematic diagram of the structure of the filtering extractor of the present invention.

FIG. 5 is a schematic view of the structure of the stirrer of the present invention.

In the figure: a fragmentation section of thick bamboo 1, pan feeding mouth 2, medicine support portion 3, hand cranking device 4, nozzle 5, honeycomb duct 6, first motor 7, second motor 8, bung 9.

Detailed Description

In order to make the objects and advantages of the present invention more apparent, the present invention will be further described in detail with reference to the following embodiments; it should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. Other systems, methods, and/or features of the present embodiments will become apparent to those skilled in the art upon review of the following detailed description. It is intended that all such additional systems, methods, features and advantages be included within this description, be within the scope of the invention, and be protected by the accompanying claims. Additional features of the disclosed embodiments are described in, and will be apparent from, the detailed description that follows.

The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by terms such as "upper", "lower", "left", "right", etc., based on the orientation or positional relationship shown in the drawings, it is only for convenience of description and simplification of description, but it is not indicated or implied that the device or component referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limitations of the present patent, and specific meanings of the terms may be understood by those skilled in the art according to specific situations.

The first embodiment.

An anti-cancer oral care solution comprising: the plant extract comprises plant extract, sodium olsulfonate, an antibacterial agent, a solubilizer, a sweetener, a thickening agent, essence, ethanol, water and a ph regulator, wherein the plant extract is obtained by extracting the following plants in parts by weight: 6-10 parts of serissa serissoides, 8-15 parts of glossy privet fruit, 8-15 parts of ficus pumila, 6-10 parts of radix rehmanniae, 6-10 parts of radix scrophulariae, 8-15 parts of radix ophiopogonis, 6-10 parts of adenophora stricta, 8-15 parts of rhizoma anemarrhenae, 3-6 parts of glabrous sarcandra herb, 10-12 parts of cortex albiziae and 6-9 parts of negundo chastetree fruit;

white horse bone: dispelling pathogenic wind, promoting diuresis, clearing heat, removing toxic substance, and is beneficial for relieving conjunctival congestion, swelling and pain, laryngalgia, and toothache;

glossy privet fruit: has mild nature, sweet and bitter taste, and has effects of nourishing yin, prolonging life, invigorating liver and kidney, clearing heat, improving eyesight, blackening hair and beard;

leaf of Ficus benjamina: sweet, slightly bitter and neutral in nature, and can clear away heat and toxic material, remove dampness and relieve itching;

radix rehmanniae: cool in nature and sweet and bitter in taste, and has effects of nourishing yin, invigorating kidney, nourishing blood, replenishing blood, and cooling blood;

figwort root: sweet, bitter, salty and slightly cold, can clear heat and cool blood, nourish yin and reduce pathogenic fire, detoxify and dissipate stagnation;

radix ophiopogonis: has effects in nourishing yin, promoting salivation, moistening lung, and relieving cough;

root of straight ladybell: sweet in taste, slightly bitter and slightly cold in nature, and can nourish yin, clear heat, moisten lung, reduce phlegm, benefit stomach and promote fluid production;

rhizoma anemarrhenae: bitter and cold, clearing heat and purging fire, nourishing yin and moistening dryness;

glabrous sarcandra herb: bitter, pungent and mild, and can clear away heat and toxic materials, cool blood, promote blood circulation, remove speckle, remove blood stasis, expel wind, remove dampness and dredge collaterals;

silktree albizzia bark: cortex Albizziae contains lignanoid glycoside, and the polysaccharide has effects of resisting tumor and inhibiting fibrosis;

vitex negundo L.var.negundo L: vitex negundo contains a large amount of vitexin, and vitexin has effects of preventing cancer, resisting tumor, and inhibiting fibrosis;

preferably, the plant extract comprises the following raw materials in proportion: 8 parts of serissa serissoides, 12 parts of glossy privet fruit, 10 parts of ficus microcarpa, 7 parts of radix rehmanniae, 9 parts of radix scrophulariae, 12 parts of radix ophiopogonis, 8 parts of adenophora stricta, 10 parts of rhizoma anemarrhenae, 6 parts of glabrous sarcandra herb, 10 parts of cortex albiziae and 8 parts of negundo chastetree fruit.

Example two.

An anti-cancer oral care solution comprising: the plant extract comprises plant extract, sodium olsulfonate, an antibacterial agent, a solubilizer, a sweetener, a thickening agent, essence, ethanol, water and a ph regulator, wherein the plant extract is obtained by extracting the following plants in parts by weight: 6-10 parts of serissa serissoides, 8-15 parts of glossy privet fruit, 8-15 parts of ficus pumila, 6-10 parts of radix rehmanniae, 6-10 parts of radix scrophulariae, 8-15 parts of radix ophiopogonis, 6-10 parts of adenophora stricta, 8-15 parts of rhizoma anemarrhenae, 3-6 parts of glabrous sarcandra herb, 10-12 parts of cortex albiziae and 6-9 parts of negundo chastetree fruit;

white horse bone: dispelling pathogenic wind, promoting diuresis, clearing heat, removing toxic substance, and is beneficial for relieving conjunctival congestion, swelling and pain, laryngalgia, and toothache;

glossy privet fruit: has mild nature, sweet and bitter taste, and has effects of nourishing yin, prolonging life, invigorating liver and kidney, clearing heat, improving eyesight, blackening hair and beard;

leaf of Ficus benjamina: sweet, slightly bitter and neutral in nature, and can clear away heat and toxic material, remove dampness and relieve itching;

radix rehmanniae: cool in nature and sweet and bitter in taste, and has effects of nourishing yin, invigorating kidney, nourishing blood, replenishing blood, and cooling blood;

figwort root: sweet, bitter, salty and slightly cold, can clear heat and cool blood, nourish yin and reduce pathogenic fire, detoxify and dissipate stagnation;

radix ophiopogonis: has effects in nourishing yin, promoting salivation, moistening lung, and relieving cough;

root of straight ladybell: sweet in taste, slightly bitter and slightly cold in nature, and can nourish yin, clear heat, moisten lung, reduce phlegm, benefit stomach and promote fluid production;

rhizoma anemarrhenae: bitter and cold, clearing heat and purging fire, nourishing yin and moistening dryness;

glabrous sarcandra herb: bitter, pungent and mild, and can clear away heat and toxic materials, cool blood, promote blood circulation, remove speckle, remove blood stasis, expel wind, remove dampness and dredge collaterals;

silktree albizzia bark: cortex Albizziae contains lignanoid glycoside, and the polysaccharide has effects of resisting tumor and inhibiting fibrosis;

vitex negundo L.var.negundo L: vitex negundo contains a large amount of vitexin, and vitexin has effects of preventing cancer, resisting tumor, and inhibiting fibrosis;

the anti-cancer effect of the finally prepared oral care solution is improved by adding the albizia bark and the negundo chastetree fruit into the formula of the plant extracting solution,

preferably, the plant extract comprises the following raw materials in proportion: 8 parts of serissa serissoides, 12 parts of glossy privet fruit, 10 parts of ficus microcarpa, 7 parts of radix rehmanniae, 9 parts of radix scrophulariae, 12 parts of radix ophiopogonis, 8 parts of adenophora stricta, 10 parts of rhizoma anemarrhenae, 6 parts of glabrous sarcandra herb, 10 parts of cortex albiziae and 8 parts of negundo chastetree fruit;

randomly dividing 90 patients diagnosed with oral submucosa fibrosis into three groups, namely a treatment group, a control group and a control group, wherein each group comprises 30 people, the treatment group uses the anti-cancer oral care solution in the morning, at noon and at night every day, the control group uses a common oral care solution in the morning, at noon and at night every day, the control group does not use the oral care solution, clinical experiments last for 2 months, and finally, the condition of the patients in the treatment group is found to be obviously better than that of the other two groups;

the method for preparing the anti-cancer oral care solution comprises the following steps:

step 1, raw material pretreatment: cleaning and drying the medicinal raw materials of serissa serissoide, glossy privet fruit, ficus microcarpa leaf, radix rehmanniae, figwort root, dwarf lilyturf tuber, adenophora stricta, rhizoma anemarrhenae, glabrous sarcandra herb, cortex albiziae and negundo chastetree fruit respectively for later use;

step 2, batching: weighing the raw material medicaments according to the weight ratio, cutting or crushing the raw materials, and uniformly mixing the cut or crushed raw material medicaments;

step 3, extraction: adding 50-70% ethanol into the uniformly mixed traditional Chinese medicines, extracting for 2-3 times, each time for 1-3 hours, controlling the temperature at 70-100 ℃, and filtering, mixing and filtering to obtain a plant extract;

step 4, preparing liquid: and (2) putting 1L of water into a stirrer, heating to 80 ℃, adding 10ml of the plant extract obtained in the step (3) while stirring, then sequentially adding 1g of sodium olsulfon, 2g of antibacterial agent, 20g of solubilizer, 15g of sweetener, 30g of thickener and 10ml of ethanol, fully stirring for 30min, uniformly mixing, then adding 6g of essence and 9g of ph regulator, uniformly mixing, then concentrating to 500ml on a rotary evaporator, and cooling to obtain the anti-cancer oral care solution.

Example three.

An anti-cancer oral care solution, comprising: the plant extract comprises plant extract, sodium olsulfonate, an antibacterial agent, a solubilizer, a sweetener, a thickening agent, essence, ethanol, water and a ph regulator, wherein the plant extract is obtained by extracting the following plants in parts by weight: 6-10 parts of serissa serissoides, 8-15 parts of glossy privet fruit, 8-15 parts of ficus pumila, 6-10 parts of radix rehmanniae, 6-10 parts of radix scrophulariae, 8-15 parts of radix ophiopogonis, 6-10 parts of adenophora stricta, 8-15 parts of rhizoma anemarrhenae, 3-6 parts of glabrous sarcandra herb, 10-12 parts of cortex albiziae and 6-9 parts of negundo chastetree fruit;

the serissa serissoides dispels wind, promotes diuresis, clears heat and detoxifies, and is beneficial to solving the problems of conjunctival congestion, swelling and pain, laryngalgia and toothache;

fructus Ligustri Lucidi is neutral in nature, sweet and bitter in taste, and has effects of nourishing yin, prolonging life, invigorating liver and kidney, clearing heat, improving eyesight, and blackening hair and beard;

the ficus microcarpa leaves are sweet, slightly bitter and neutral in nature, and can clear away heat and toxic materials, remove dampness and relieve itching;

the dried rehmannia root is cool in nature and sweet and bitter in taste, and has the effects of nourishing yin, tonifying kidney, nourishing blood, enriching blood and cooling blood;

radix scrophulariae is sweet, bitter, salty and slightly cold in taste, and can clear heat and cool blood, nourish yin and reduce pathogenic fire, detoxify and dissipate stagnation;

radix Ophiopogonis has effects in nourishing yin, promoting fluid production, moistening lung, and relieving cough;

the root of straight ladybell is sweet in taste, slightly bitter in taste and slightly cold in nature, and can nourish yin, clear heat, moisten lung, reduce phlegm, benefit stomach and promote fluid production;

rhizoma anemarrhenae is bitter and cold in taste, clears heat and purges fire, and nourishes yin and moistens dryness;

the glabrous sarcandra herb is bitter, pungent and even in flavor, and can clear away heat and toxic materials, cool blood, promote blood circulation, remove speckles, dissipate blood stasis, dispel wind, remove dampness and dredge collaterals;

cortex Albizziae contains lignan glycoside, which has effects of resisting tumor and inhibiting fibrosis;

vitex negundo contains a large amount of vitexin, which has effects of preventing cancer, resisting tumor, and inhibiting fibrosis;

the plant extract comprises the following raw materials in percentage by weight: 8 parts of serissa serissoides, 12 parts of glossy privet fruit, 10 parts of ficus microcarpa, 7 parts of radix rehmanniae, 9 parts of radix scrophulariae, 12 parts of radix ophiopogonis, 8 parts of adenophora stricta, 10 parts of rhizoma anemarrhenae, 6 parts of glabrous sarcandra herb, 10 parts of cortex albiziae and 8 parts of negundo chastetree fruit;

the preparation method of the anti-cancer oral care solution specifically comprises the following steps:

step 1, raw material pretreatment: cleaning and drying the medicinal raw materials of serissa serissoide, glossy privet fruit, ficus microcarpa leaf, radix rehmanniae, figwort root, dwarf lilyturf tuber, adenophora stricta, rhizoma anemarrhenae, glabrous sarcandra herb, cortex albiziae and negundo chastetree fruit respectively for later use;

step 2, batching: weighing the raw material medicaments according to the weight ratio, cutting or crushing the raw materials, and uniformly mixing the cut or crushed raw material medicaments;

step 3, extraction: adding 50-70% ethanol into the uniformly mixed medicines, extracting for 2-3 times, each time for 1-3 hours, controlling the temperature at 70-100 ℃, and filtering, mixing and filtering to obtain a plant extract;

step 4, preparing liquid: putting 1L of water into a stirrer, heating to 80 ℃, adding 10ml of the plant extract obtained in the step 3 while stirring, then sequentially adding 1g of sodium olsulfon, 2g of antibacterial agent, 20g of solubilizer, 15g of sweetener, 30g of thickener and 10ml of ethanol, fully stirring for 30min, uniformly mixing, then adding 6g of essence and 9g of ph regulator, uniformly mixing, then concentrating to 500ml on a rotary evaporator, and cooling to obtain the anti-cancer oral care solution;

the device for preparing the anti-cancer oral care solution comprises a disintegrator, a filtering extractor, a stirrer and a bracket fixedly connected with the disintegrator, the filtering extractor and the stirrer;

the disintegrator comprises a feeding port, a disintegrating cylinder, a fixing frame and a discharging port, the discharging port and the fixing frame are respectively connected with two ends of the disintegrating cylinder, the discharging port comprises a connecting ring, a handheld ring and a medicine support part, the handheld ring is fixedly connected with the connecting ring, the medicine support part is fixedly connected with the handheld ring, the inner diameter of the handheld ring is the same as the inner diameter of the connecting ring, the outer diameter of the handheld ring is larger than the outer diameter n mm of the connecting ring, n is not larger than 3, the medicine support part is formed by longitudinally extending partial edges of the handheld ring and is arc-shaped, the connecting ring is provided with external threads which are matched with the internal threads at one end of the disintegrating cylinder, the discharging port is connected with the disintegrating cylinder through grabbing the handheld ring and rotating, and the threads are arranged when the discharging port is connected to the deepest part, the medicine support part is positioned right below the medicine support part;

the upper part of the smashing cylinder is provided with a V-shaped opening, the feeding port is funnel-shaped and comprises a bowl-shaped body and a communicating pipe, a round opening is arranged below the bowl-shaped body, and the communicating pipe is connected to the round opening and is seamlessly inserted into the V-shaped opening;

the medicine crushing device is characterized in that a threaded rod is arranged in the crushing cylinder, the threaded rod penetrates through one end of the crushing cylinder and extends outwards to form a thin rod, the thread space of the threaded rod is continuously reduced along the direction close to the discharge port, the protruding part of the thread is in a sharp shape, the threaded rod plays a role in cutting medicines when rotating, a hand-cranking device is further connected onto the thin rod and comprises a supporting rod and a hand-cranking rod, the supporting rod and the hand-cranking rod are vertically connected, a sleeving ring is arranged at one end of the supporting rod and sleeved on the thin rod, the sleeving ring is fixedly connected with the thin rod, the relative position of the hand-cranking device cannot be changed, relative rotation and sliding cannot occur, and the threaded rod can be rotated and crushed by shaking the hand-cranking rod;

the hand rocker is an electric rocker and provides driving force by a motor;

the fixed frame is sleeved on the support rod, a bolt is arranged at the joint of the fixed frame and the support rod, when the bolt is loosened, the fixed frame can rotate around the support rod, so that the angle of the whole shredder is adjusted, and when the bolt is tightened, the whole shredder is fixed relative to the support rod; when the medicine is crushed, the crusher is adjusted to the inclination angle with the discharge port facing upwards, so that the crushing is more sufficient, and after the crushing is finished, the crusher is adjusted to the inclination angle with the discharge port facing downwards, so that the medicine is convenient to pour out;

the filtering extractor is a cylinder body, a medicine tube is arranged in the center inside the cylinder body, tiny holes for liquid to flow through are formed in the whole body of the medicine tube, a cylinder opening is formed in the upper portion of the medicine tube and faces a discharge hole of the smashing cylinder, medicine enters the medicine tube through the cylinder opening, an openable switch is arranged on the upper portion of the medicine tube and is closed after the medicine and alcohol are placed, a solvent cylinder is arranged on the outer side of the medicine tube and wraps the medicine tube, 50-70% of ethanol solution is stored in the solvent cylinder, when the medicine tube is closed, the ethanol and the medicine are in a completely closed state, a heating device covers the outer wall of the solvent cylinder and comprises four vertical plates and heating devices connected among the vertical plates, the vertical plates play a role in fixing, and thermal resistors are arranged in the heating horizontal plates, the thermal resistor is attached to the outer wall of the solvent cylinder, the outer wall of the solvent cylinder is made of metal with strong thermal conductivity, a rotary disc is arranged below the solvent cylinder, the rotary disc is fixedly connected with the solvent cylinder, the solvent cylinder and the medicine tube can rotate together with the rotary disc, thereby accelerating the speed of dissolving the soluble substances in the medicine into the alcohol, the lower part of the turntable is connected with a chassis, a transparent cover is arranged on the outer side of the solvent cylinder, the transparent cover is connected with the chassis in a seamless manner, a liquid outlet is also arranged on the solvent cylinder, when the extraction time of the medicine in the alcohol is satisfied, the liquid outlet is opened, the medicine extracting solution flows out of the liquid outlet into the transparent cover, the lower part of the transparent cover is provided with a flow guide pipe for transferring and collecting the extracting solution in the transparent cover, extracting for three times repeatedly and mixing the extracting solution to obtain the final plant extracting solution;

the agitator is a cask, is equipped with first stirring spare and second stirring spare in the cask, first stirring spare is located the cask bottom, second stirring spare is located the cask lateral wall, first stirring spare includes first column spinner and three stirring leaf, the stirring leaf transversely runs through first column spinner and two liang between become 60 degrees angles, three stirring leaf are in different heights, two stirring leaf shapes that are located below are the same, including the horizontal plate that runs through first column spinner and the hang plate of connection at the horizontal plate both ends, the inclination of hang plate is 15 degrees, the stirring leaf that is located above includes the horizontal plate that runs through first column spinner, connects the hang plate at the horizontal plate both ends and the horizontal end plate that links to each other with the hang plate, the inclination of hang plate is 15 degrees, be equipped with first motor below the cask, the output shaft of first motor run through the cask and with the first column spinner of first stirring spare links to each other, the second stirring part comprises a second rotating column and six stirring blades, the stirring blades are inserted into the second rotating column in pairs, the stirring blades are rectangular plates, each pair of rectangular plates are positioned at different heights, the central axes of the rectangular plates form 60-degree angles, the two rectangular plates of each pair of stirring blades and the vertical plane of the central axis of the rectangular plates respectively form +/-15-degree angles, a second motor is arranged on the outer wall of the barrel, the output shaft of the second motor is connected with the second rotating column of the second stirring part, a protective cover is further arranged between the second motor and the outer wall, a barrel cover is arranged above the barrel and is rotatably connected with the barrel, a handheld frame and a material conveying hole for grabbing and opening the barrel cover are arranged on the barrel cover, other ingredients can be added through the material conveying hole when the barrel cover is closed for stirring, and two fixing rods are further arranged on the outer side of the barrel and are connected with the support, and plays a role in fixing the drum.

Although the invention has been described above with reference to various embodiments, it should be understood that many changes and modifications may be made without departing from the scope of the invention. That is, the methods, systems, and devices discussed above are examples. Various configurations may omit, substitute, or add various procedures or components as appropriate. For example, in alternative configurations, the methods may be performed in an order different than that described, and/or various components may be added, omitted, and/or combined. Moreover, features described with respect to certain configurations may be combined in various other configurations, as different aspects and elements of the configurations may be combined in a similar manner. Further, elements therein may be updated as technology evolves, i.e., many elements are examples and do not limit the scope of the disclosure or claims.

Specific details are given in the description to provide a thorough understanding of the exemplary configurations including implementations. However, configurations may be practiced without these specific details, for example, well-known circuits, processes, algorithms, structures, and techniques have been shown without unnecessary detail in order to avoid obscuring the configurations. This description provides example configurations only, and does not limit the scope, applicability, or configuration of the claims. Rather, the foregoing description of the configurations will provide those skilled in the art with an enabling description for implementing the described techniques. Various changes may be made in the function and arrangement of elements without departing from the spirit or scope of the disclosure.

In conclusion, it is intended that the foregoing detailed description be regarded as illustrative rather than limiting, and that it be understood that these examples are illustrative only and are not intended to limit the scope of the invention. After reading the description of the invention, the skilled person can make various changes or modifications to the invention, and these equivalent changes and modifications also fall into the scope of the invention defined by the claims.

Claims (3)

1. An anti-cancer oral care solution, comprising: the plant extract comprises plant extract, sodium olsulfonate, an antibacterial agent, a solubilizer, a sweetener, a thickening agent, essence, ethanol, water and a ph regulator, wherein the plant extract is obtained by extracting the following plants in parts by weight: 6-10 parts of serissa serissoides, 8-15 parts of glossy privet fruit, 8-15 parts of ficus pumila, 6-10 parts of radix rehmanniae, 6-10 parts of radix scrophulariae, 8-15 parts of radix ophiopogonis, 6-10 parts of adenophora stricta, 8-15 parts of rhizoma anemarrhenae, 3-6 parts of glabrous sarcandra herb, 10-12 parts of cortex albiziae and 6-9 parts of negundo chastetree fruit.

2. The anti-cancer oral care solution of claim 1, wherein: the plant extract is obtained by extracting the following plants in parts by weight: 8 parts of serissa serissoides, 12 parts of glossy privet fruit, 10 parts of ficus microcarpa, 7 parts of radix rehmanniae, 9 parts of radix scrophulariae, 12 parts of radix ophiopogonis, 8 parts of adenophora stricta, 10 parts of rhizoma anemarrhenae, 6 parts of glabrous sarcandra herb, 10 parts of cortex albiziae and 8 parts of negundo chastetree fruit.

3. A process for preparing an anti-cancer oral care solution according to any preceding claim, comprising the steps of:

step 1, raw material pretreatment: cleaning and drying the medicinal raw materials of serissa serissoide, glossy privet fruit, ficus microcarpa leaf, radix rehmanniae, figwort root, dwarf lilyturf tuber, adenophora stricta, rhizoma anemarrhenae, glabrous sarcandra herb, cortex albiziae and negundo chastetree fruit respectively for later use;

step 2, batching: weighing the raw material medicaments according to the weight ratio, cutting or crushing the raw materials, and uniformly mixing the cut or crushed raw material medicaments;

step 3, extraction: adding 5-20 times of water or 50-70% ethanol into the uniformly mixed traditional Chinese medicines, extracting for 2-3 times, each time for 1-3 hours, controlling the temperature at 70-100 ℃, and filtering, mixing and filtering to obtain a plant extracting solution;

step 4, preparing liquid: and (2) putting 1L of water into a stirrer, heating to 80 ℃, adding 10ml of the plant extract obtained in the step (3) while stirring, then sequentially adding 1g of sodium olsulfon, 2g of antibacterial agent, 20g of solubilizer, 15g of sweetener, 30g of thickener and 10ml of ethanol, fully stirring for 30min, uniformly mixing, then adding 6g of essence and 9g of ph regulator, uniformly mixing, and concentrating to 500ml on a rotary evaporator to obtain the anticancer oral care solution.

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