CN101972220B - Medicated toothpaste - Google Patents
Medicated toothpaste Download PDFInfo
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- CN101972220B CN101972220B CN 201010523150 CN201010523150A CN101972220B CN 101972220 B CN101972220 B CN 101972220B CN 201010523150 CN201010523150 CN 201010523150 CN 201010523150 A CN201010523150 A CN 201010523150A CN 101972220 B CN101972220 B CN 101972220B
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- medicated toothpaste
- toothpaste
- medicated
- herba erigerontis
- extract
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Abstract
The invention relates to a toothpaste, in particular to a medicated toothpaste. A paste body of the medicated toothpaste contains erigeron breviscapus extract. The erigeron breviscapus extract accounts for 0.1-25% by weight of the paste body of the medicated toothpaste, the preferential weight ratio is 0.5-10%, and the optimal weight ratio is 1-5%. The erigeron breviscapus extract is dry powder of ethanol extract or the dry powder of the extract obtained by the water decoction method. The application of the medicated toothpaste has the following benefits: the medicated toothpaste has extensive efficacy and obvious effects of eliminating inflammation, relieving pain and preventing periodontitis, gingivitis, halitosis, saprodontia and oral ulcers, and is simultaneously particularly applicable to people groups with high risk of having cerebrovascular diseases and the like; in addition, the cost is low, and erigeron breviscapus has the characteristics of extensive distribution and cheap price, thereby being capable of effectively reducing the cost of producing the medicated toothpaste.
Description
Technical field
The present invention relates to a kind of toothpaste, more particularly, relate to a kind of medicated toothpaste.
Background technology
Enhancing day by day along with consumer healthcare's consciousness is requiring outside the outstanding function that cleans the teeth toothpaste, has also proposed the demand of more MC health cares, such as auxiliary prevention or treatment oral disease.At present various functional product demands grow with each passing day in the toothpaste market, and become the market mainstream, and wherein Chinese herbal medicine toothpaste is natural because of its effect additive, effect is remarkable and characteristics such as safety height are firmly got consumer's favor.So on the market be the emphasis that the functional toothpaste of effective ingredient becomes current development with the active ingredient of Chinese herbs.
Also have in the prior art and adopt various active ingredient of Chinese herbs as the toothpaste ancillary drug, like tianqi toothpaste, YUNNAN BAIYAO toothpaste, shiny pricklyash toothpaste etc., effect is had nothing in common with each other.With the medicated toothpaste with antiinflammatory, analgesic activity is example, existing this type of toothpaste such as: like Yunnan BAIYAO toothpaste, tianqi toothpaste, the main functional component that is adopted is a pseudo-ginseng, and this medical material distribution region is few, and growth cycle is long and price is high.
Summary of the invention
The technical problem that the present invention will solve is, adopts the defective of expensive medical material to prior art, and a kind of medicated toothpaste is provided.
The technical solution adopted for the present invention to solve the technical problems is: a kind of medicated toothpaste is provided, it is characterized in that, contain Herba Erigerontis extract in the said medicated toothpaste mastic.
In medicated toothpaste of the present invention, the weight ratio that said Herba Erigerontis extract accounts for said medicated toothpaste mastic is 0.1～25%.
In medicated toothpaste of the present invention, the weight ratio that said Herba Erigerontis extract accounts for said medicated toothpaste mastic is 0.5～10%.
In medicated toothpaste of the present invention, the weight ratio that said Herba Erigerontis extract accounts for said medicated toothpaste mastic is 1～5%.
In medicated toothpaste of the present invention, also contain abrasivus, wetting agent, foaming agent, thickening agent in the said medicated toothpaste mastic.
In medicated toothpaste of the present invention, contain following compositions in portion by weight in the said medicated toothpaste mastic:
Abrasivus 10～50;
Wetting agent 5～40;
Foaming agent 0.1～10;
Thickening agent 0.1～6.
In medicated toothpaste of the present invention, also contain the raw material of following parts by weight in the said medicated toothpaste mastic:
Dicalcium phosphate dihydrate 30～50;
Silica 1～10;
Glycerol 5～15;
Sorbitol 5～15;
Carboxymethyl cellulose 0.5～2;
Sodium laurylsulfate 3～8;
Essence 0.5～1.5;
Sweeting agent 0.1～0.3;
In medicated toothpaste of the present invention, said Herba Erigerontis extract is the dried powder of ethanol extraction.
In medicated toothpaste of the present invention, said Herba Erigerontis extract is the dried powder of decocting cooking method extract.
The medicated toothpaste of embodiment of the present invention, have following beneficial effect: drug effect is wide, has tangible anti-inflammatory analgetic, and the effect of prevention periodontitis, gingivitis, halitosis, dental caries, oral ulcer also is specially adapted to excessive risk afflicted such as cerebrovascular simultaneously; Cost is low, because the Herba Erigerontis distribution is extensive, cheap, can reduce the cost of producing this medicated toothpaste effectively in addition.
The specific embodiment
Herba Erigerontis, Latin formal name used at school Herba Erigerontis, Compositae Herba Erigerontis aceris platymiscium Erigeron breviscapus (Vant.) Hand.-Mazz. is used as medicine with herb or root.Autumn stem and leaf luxuriant the flowers are in blossom gathers when putting, clean using fresh herb or dry.Nature and flavor are hot, little hardship, temperature.But expelling cold and relieving exterior syndrome, expelling wind and removing dampness, activating collaterals to relieve pain.Be used for headache due to common cold, toothache, stomachache, rheumatalgia, the paralysis that cerebrovascular accident causes, osteomyelitis.Clinical research shows: Herba Erigerontis has certain curative effect for back something lost such as treatment hypertensive cerebral hemorrhage, cerebral thrombosis, cerebral embolism, polyneuritis, chronic arachnoiditis paralysed disease.
The xeraphium of Herba Erigerontis extract all is after its crude drug is the ethanol extraction method acquisition ethanol extraction of solvent through routine with ethanol, the dry extract powder that obtains.Conventional ethanol extraction method has: cold-maceration, percolation, circumfluence method, ultrasonic method etc.The xeraphium of Herba Erigerontis extract also can dissolve crude drug water decocting method with effective ingredient after, the dry extract powder that obtains.But the extracts active ingredients efficient of decocting cooking method is lower.
Herba Erigerontis is widely distributed in China western part and west and south Zhong Shan and open patana of inferior high mountain and border, and price only is about about 15% of Radix Notoginseng.So far do not have as yet and use Herba Erigerontis as the research of auxiliary Chinese medicine ingredients in the toothpaste or the report of using.
In the medicated toothpaste of the present invention, except that said Herba Erigerontis extract, also comprise the base stock of the preparation toothpaste such as abrasivus, wetting agent, foaming agent, thickening agent, flavoring agent and essence in the formulation of tooth-paste and an amount of water.Abrasivus can be calcium carbonate, calcium hydrogen phosphate; Wetting agent can be xylitol, Polyethylene Glycol, sorbitol, glycerol; Foaming agent can be anion surfactant such as sodium lauryl sulphate, lauroyl propylhomoserin sodium, also can be non-ionic surface active agent such as lauryl alcohol diethanolamine, dodecyl amine oxide, tween.
Below in conjunction with embodiment, the present invention is further specified.Data related in the following table are meant parts by weight, and the total weight parts number average of embodiment 1 to embodiment 6 Chinese medicine lotion of toothpaste is 100.
Table 1, the formula ratio of each raw material among the embodiment 1 to embodiment 6
Core of the present invention is to adopt Herba Erigerontis extract to add in the toothpaste as functional component and verifies its analgesia, anti-inflammatory effect in toothpaste, and obtains the optimum optimization percentage by weight that said Herba Erigerontis extract accounts for lotion of toothpaste through experimental study.Can be found out that by last table Herba Erigerontis extract parts by weight maximum gets 25 among the embodiment 1 to embodiment 6, minima gets 0.1, and intermediate value gets 0.5,1,5 and 10.According to the formula ratio in the last table; Get the Herba Erigerontis extract of Different Weight umber; Repeat repeatedly formula test, entrust respectively 20 often the volunteer of toothache and gingival hemorrhage carry out effect assessment, frequency of utilization be every day early, evening respectively once; The about 1g mastic of consumption/each, each about 5min of brushing time.The result who obtains shows that the medicated toothpaste that contains Herba Erigerontis has tangible analgesia, antiinflammatory and prevents the effect of gingival hemorrhage; And from using mouthfeel and drug effect two aspect evaluations; The weight ratio that Herba Erigerontis extract accounts for this medicated toothpaste mastic is 0.1～25% more suitable; Be optimized for 0.5～10%, optimum optimization is 1～5%.When the weight ratio that accounts for this medicated toothpaste mastic when Herba Erigerontis extract was 1～5%, the drug effect and the mouthfeel of toothpaste were in optimum balance.
Method for preparing:
In above-mentioned each item embodiment, arbitrary method was processed below Herba Erigerontis extract can adopt.
1), get the Herba Erigerontis herb, pulverize and be coarse powder, the alcohol reflux with 60%～90% 3 times, each 2 hours, Herba Erigerontis coarse powder and ethanol weight ratio were 1: 5～1: 10, and extracting solution is merged, concentrating under reduced pressure is dried to powder.
2), get the Herba Erigerontis herb, pulverize and be coarse powder, decoct 3 times with hot water, each 3 hours, the weight ratio of Herba Erigerontis coarse powder and water was 1: 5～1: 10, mistake filters to remove residue, the merging of will filtrating, concentrate drying becomes powder.
In above-mentioned each item embodiment, the medicated toothpaste mastic can adopt following method to process.
1) according to formula ratio carboxymethyl cellulose is added in the part water, and heating for dissolving, if any insoluble matter, then remove by filter, make cmc soln, subsequent use.
2) according to formula ratio glycerol, sorbitol, sodium laurylsulfate, essence, sweeting agent and Herba Erigerontis extract are added in the part water, and stir, make drug solution, subsequent use.
3) with the cmc soln and the step 2 that make in the step 1)) in the drug solution that makes fully mix; Add the water that dicalcium phosphate dihydrate, silicon dioxide and residue should add successively according to formula ratio; After fully stirring, grind to form thin paste, divide at last to install in the dentifrice tube.
Herba Erigerontis extract is added in the toothpaste as the natural medicinal plants active component raw material, gives the significant antiinflammatory of this medicated toothpaste, analgesic activity; And these medicine material wide material sources; With low cost, be merely about 15% of pseudo-ginseng, be suitable as effective medicinal herb components of toothpaste.
The above is merely embodiments of the invention; Be not so limit claim of the present invention; Every equivalent structure transformation that utilizes description of the present invention to do, or directly or indirectly be used in other relevant technical fields, all in like manner be included in the scope of patent protection of the present invention.
Claims (6)
1. a medicated toothpaste is characterized in that, contains Herba Erigerontis extract in the said medicated toothpaste mastic, and the weight ratio that said Herba Erigerontis extract accounts for said medicated toothpaste mastic is 0.1 ~ 25%;
Also contain abrasivus, wetting agent, foaming agent, thickening agent in the said medicated toothpaste mastic, its parts by weight:
Abrasivus 10 ~ 50;
Wetting agent 5 ~ 40;
Foaming agent 0.1 ~ 10;
Thickening agent 0.1 ~ 6.
2. medicated toothpaste according to claim 1 is characterized in that, the weight ratio that said Herba Erigerontis extract accounts for said medicated toothpaste mastic is 0.5 ~ 10%.
3. medicated toothpaste according to claim 2 is characterized in that, the weight ratio that said Herba Erigerontis extract accounts for said medicated toothpaste mastic is 1 ~ 5%.
4. according to any described medicated toothpaste in the claim 1 to 3, it is characterized in that, also contain the raw material of following parts by weight in the said medicated toothpaste mastic:
Dicalcium phosphate dihydrate 30 ~ 50;
Silica 1 ~ 10;
Glycerol 5 ~ 15;
Sorbitol 5 ~ 15;
Carboxymethyl cellulose 0.5 ~ 2;
Sodium laurylsulfate 3 ~ 8;
Essence 0.5 ~ 1.5;
Sweeting agent 0.1 ~ 0.3.
5. according to any described medicated toothpaste in the claim 1 to 3, it is characterized in that said Herba Erigerontis extract is the dried powder of ethanol extraction.
6. according to any described medicated toothpaste in the claim 1 to 3, it is characterized in that said Herba Erigerontis extract is the dried powder of decocting cooking method extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010523150 CN101972220B (en) | 2010-10-28 | 2010-10-28 | Medicated toothpaste |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010523150 CN101972220B (en) | 2010-10-28 | 2010-10-28 | Medicated toothpaste |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101972220A CN101972220A (en) | 2011-02-16 |
| CN101972220B true CN101972220B (en) | 2012-12-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010523150 Expired - Fee Related CN101972220B (en) | 2010-10-28 | 2010-10-28 | Medicated toothpaste |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610722A (en) * | 2013-12-13 | 2014-03-05 | 沈阳药科大学 | Asarum heterotropoide extract, preparation method and application of extract |
| CN106344443A (en) * | 2016-08-24 | 2017-01-25 | 彭友莲 | Caring type toothpaste and preparation method thereof |
| CN107334827A (en) * | 2017-07-19 | 2017-11-10 | 合肥浦邦农业科技有限公司 | A kind of anti-inflammatory shield anti-halitosis more effect toothpaste of tooth and preparation method thereof |
| CN107320398A (en) * | 2017-08-16 | 2017-11-07 | 何家平 | A kind of Chinese herbal medicine children's toothpaste |
| CN109044902A (en) * | 2018-08-17 | 2018-12-21 | 王凡 | A kind of lamp-dish flower acetic toothpaste and its application |
-
2010
- 2010-10-28 CN CN 201010523150 patent/CN101972220B/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 杨文宇等.灯盏细辛的民族民间用药研究概况.《成都中医药大学学报》.2005,第28卷(第1期),63. * |
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| CN101972220A (en) | 2011-02-16 |
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Owner name: SHENZHEN UNI-MEDICAL TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: SHENZHEN SANGEL VENTURE CAPTICAL CO., LTD. Effective date: 20130621 |
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Effective date of registration: 20130621 Address after: 518000 Guangdong city of Shenzhen province Nanshan District Xili sangtai Science Park building 201 Patentee after: Shenzhen Uni-Medica Technology Co., Ltd. Address before: Seven, building 5, building 708, Donghua garden, Nanhai Avenue, Shenzhen, Nanshan District 518054, Guangdong Patentee before: Shenzhen Sage Angel Venture Capital Man Co Ltd |
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