CN112315856A - Multifunctional traditional Chinese medicine toothpaste and preparation method thereof - Google Patents

Multifunctional traditional Chinese medicine toothpaste and preparation method thereof Download PDF

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CN112315856A
CN112315856A CN201911096824.2A CN201911096824A CN112315856A CN 112315856 A CN112315856 A CN 112315856A CN 201911096824 A CN201911096824 A CN 201911096824A CN 112315856 A CN112315856 A CN 112315856A
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toothpaste
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冼国茂
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Sheng Guomao
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Sheng Guomao
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
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    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The invention discloses a multifunctional traditional Chinese medicine toothpaste and a preparation method thereof, and relates to the technical field of toothpaste, wherein the traditional Chinese medicine toothpaste comprises the following components in parts by weight: 3-9 parts of poria cocos extract, 0.5-1.5 parts of salvia miltiorrhiza extract, 0.5-1.5 parts of pseudo-ginseng extract, 0.5-1.5 parts of south Africa leaf extract and 88-96 parts of toothpaste matrix. The health care tea is scientific and reasonable in structure and convenient to operate, the poria cocos is added in the raw materials, the health care tea is a rare product used as both medicine and food, and has an important nourishing effect, the active ingredients of the Chinese herbal medicines, namely the salvia miltiorrhiza and the pseudo-ginseng, are added in the formula of the health care tea, the health care tea is prepared according to the theory of traditional Chinese medicine, the effect of treating both symptoms and root causes of diseases due to deficiency of heart and spleen is achieved through compatibility of medicines, the medicines are dissolved into saliva by daily tooth brushing, and permeate, diffuse and absorb through oral mucosa, sublingual capillary vessels and meridian points, and directly enter blood circulation, so that the health care tea is used for replacing.

Description

Multifunctional traditional Chinese medicine toothpaste and preparation method thereof
Technical Field
The invention relates to the technical field of toothpaste, in particular to a multifunctional traditional Chinese medicine toothpaste and a preparation method thereof.
Background
Deficiency of both heart and spleen belongs to a syndrome type in traditional Chinese medicine, a term of traditional Chinese medicine. Deficiency of both heart and spleen refers to the condition of both heart-blood deficiency and spleen-qi deficiency. Palpitations, insomnia, dreamful sleep, amnesia, poor appetite, abdominal distension and the like are the main clinical manifestations. Its harm can affect the system of nerve reproduction, and the most important is also insomnia and palpitation. The clinical symptoms of heart-spleen deficiency are mainly manifested as palpitation, severe palpitation, insomnia, dreaminess, dizziness, amnesia, etc. At present, the conservative estimation of patients with insomnia and other diseases caused by heart-spleen deficiency in China exceeds 1 hundred million people, the existing medicines for clinically preventing and treating heart-spleen deficiency are taken orally, and are troublesome, and especially for old patients, the patients often forget to take the medicines or are inconvenient to take the medicines, which brings great inconvenience to the prevention and treatment of heart-spleen deficiency.
As a necessity for cleaning teeth and protecting oral hygiene, toothpaste has been used by consumers for a long time in the morning and evening of the day. With the enhancement of health care consciousness of consumers, more health care functional demands are put forward to toothpaste, and prevention and treatment of certain diseases, such as auxiliary prevention and treatment of chronic diseases such as oral diseases, cardiovascular and cerebrovascular diseases and the like, can be expected while brushing teeth. At present, functional toothpaste added with traditional Chinese medicine active ingredients, such as pseudo-ginseng toothpaste, radix zanthoxyli toothpaste, Yunnan white medicine toothpaste, salvia miltiorrhiza toothpaste and the like, appear in the toothpaste market, but the efficacy of the toothpaste only stays in preventing and treating oral diseases or other diseases. Therefore, how to research and develop toothpaste with better effect for preventing and treating the diseases of deficiency of both heart and spleen according to the theory of traditional Chinese medicine is a problem to be solved in the existing market urgently when the toothpaste is used for replacing patients with the diseases of deficiency of both heart and spleen to take medicines for a long time. Therefore, the technical personnel in the field provide a multi-functional traditional Chinese medicine toothpaste and a preparation method thereof to solve the problems in the background technology.
Disclosure of Invention
The invention aims to provide a multifunctional traditional Chinese medicine toothpaste and a preparation method thereof, and aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a multifunctional traditional Chinese medicine toothpaste comprises the following components in parts by weight: 3-9 parts of poria cocos extract, 0.5-1.5 parts of salvia miltiorrhiza extract, 0.5-1.5 parts of pseudo-ginseng extract, 0.5-1.5 parts of south Africa leaf extract and 88-96 parts of toothpaste matrix; the matrix for the toothpaste comprises the following components in parts by weight: 15-50 parts of an abrasive agent, 5-35 parts of a humectant, 1-5 parts of a foaming agent, 0.5-3 parts of a thickening agent, 0-1 part of a sweetening agent, 0-2 parts of a spice, 0-0.5 part of a preservative, 1-40 parts of deionized water and 0-1.5 parts of an edible pigment.
As a further scheme of the invention: the friction agent is selected from one or more of calcium hydrophosphate dihydrate, anhydrous calcium hydrophosphate, calcium pyrophosphate, anhydrous silicon dioxide, calcite powder and chlorite; the humectant is selected from one or more of glycerol, sorbitol, propylene glycol and polyethylene glycol; the foaming agent is selected from one or more of sodium dodecyl sulfate, N-lauroyl sarcosine sodium, methyl cocoyl sodium taurate and acyl sodium glutamate; the thickening agent is selected from one or more of sodium alginate, carboxymethyl cellulose, hydroxyethyl cellulose, xanthan gum powder and hydroxypropyl guar gum; the sweetener is one or more selected from sucrose, saccharin, sodium cyclamate, xylitol and sodium diaminate; the spice is selected from one or more of perilla oil, peppermint oil, lemon oil, spearmint oil, orange oil, wintergreen oil, clove oil, cinnamon oil, anise oil, menthol, borneol, citral, laurylaldehyde, vanillin and amyl acetate; the preservative is selected from one or more of p-hydroxybenzoate, sodium benzoate, potassium sorbate and sorbitol; the deionized water is a gel-forming dispersion medium of the toothpaste; the edible pigment is green or purple.
As a still further scheme of the invention: the poria cocos extract is prepared by the following method: removing impurities from the selected poria cocos medicinal materials, crushing, extracting with water, decoloring a concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
As a still further scheme of the invention: the poria cocos extract can also be prepared by adopting the following method: removing impurities from the selected poria cocos medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing extraction for 0.5 hour each time, decoloring a concentrated solution by using activated carbon, and concentrating the decolored concentrated solution into an extract with the relative density of 1.10-1.30.
As a still further scheme of the invention: the salvia miltiorrhiza extract is prepared by the following method: removing impurities from a carefully selected salvia miltiorrhiza medicinal material, crushing, extracting with water, decoloring a concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
As a still further scheme of the invention: the salvia miltiorrhiza extract can also be prepared by the following method: removing impurities from a selected salvia miltiorrhiza medicinal material, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, wherein each time is 0.5h, and concentrating a concentrated solution after decoloring by using activated carbon into an extract with the relative density of 1.10-1.30.
As a still further scheme of the invention: the pseudo-ginseng extract is prepared by adopting the following method: removing impurities from the selected pseudo-ginseng medicinal materials, crushing, extracting with water, decoloring a concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
As a still further scheme of the invention: the pseudo-ginseng extract can also be prepared by adopting the following method: removing impurities from selected pseudo-ginseng medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing each time for 0.5h, decoloring a concentrated solution by using activated carbon, and concentrating the decolored concentrated solution into an extract with the relative density of 1.10-1.30.
As a still further scheme of the invention: the south Africa leaf extract is prepared by the following method: removing impurities from a selected south Africa leaf medicinal material, crushing, carrying out water extraction, decoloring a concentrated solution by using activated carbon, and concentrating into an extract with the relative density of 1.10-1.30; the south Africa leaf can also be prepared by adopting the following method: removing impurities from the selected south Africa leaf medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing each time for 0.5h, decoloring the concentrated solution by using activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
A preparation method of a multifunctional traditional Chinese medicine toothpaste comprises the following steps:
s1: preparing raw materials: preparing Poria extract, Saviae Miltiorrhizae radix extract, Notoginseng radix extract, folium Africae extract and toothpaste matrix;
s2: weighing raw materials: weighing the required weight parts of tuckahoe extract, salvia miltiorrhiza extract, panax notoginseng extract, south Africa leaf extract and toothpaste matrix according to the mixture ratio requirement;
s3: mixing and filling: mixing the above weighed Poria extract, Saviae Miltiorrhizae radix extract, Notoginseng radix extract, folium Africae extract and toothpaste matrix, homogenizing in vacuum paste making machine, and packaging.
Compared with the prior art, the invention has the beneficial effects that: the poria cocos is added into the raw materials, is sweet and light in taste, has a neutral nature, has the effects of promoting diuresis and excreting dampness, tonifying spleen and calming heart, is commonly used for treating symptoms such as edema, oliguria, palpitation due to phlegm and fluid retention, spleen deficiency, poor appetite, uneasiness, palpitation, insomnia and the like, and has an important nourishing effect; the formula of the invention is added with Chinese herbal medicine active ingredients of salvia miltiorrhiza and pseudo-ginseng, wherein the salvia miltiorrhiza is bitter in taste and slightly cold, and has the effects of activating blood and dissolving stasis, stimulating menstrual flow and relieving pain, clearing away heart-fire and relieving restlessness, cooling blood and eliminating carbuncle; the radix notoginseng is warm in nature and pungent in taste, has remarkable effects of promoting blood circulation to remove blood stasis, relieving swelling and relieving pain, is prepared from the radix salviae miltiorrhizae and the radix notoginseng according to the theory of traditional Chinese medicine, and has the effect of treating both symptoms and root causes for heart-spleen deficiency diseases; the south Africa leaf extract is added in the formula, is bitter and cold in nature, and has the effects of clearing heat and removing toxicity, eliminating dampness and killing insects and protecting gingiva; the medicine is dissolved into saliva by a user through daily tooth brushing, and is permeated, diffused and absorbed through oral mucosa, sublingual capillary vessels and meridian points, the damage of gastrointestinal tracts, liver and kidney to the medicine is avoided, the medicine directly enters blood circulation, the medicine is used for replacing patients with heart-spleen deficiency diseases to take for a long time, meanwhile, the stomatitis is improved, and the medicine has the advantages of multiple effects and remarkable health care effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Preparing raw materials:
and (3) poria cocos extract: removing impurities from the selected poria cocos medicinal materials, crushing, carrying out water extraction, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30, or removing impurities from the selected poria cocos medicinal materials, crushing, carrying out reflux extraction for 1-3 times with 50% (V/V) ethanol for 0.5h each time, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
The red sage root extract: removing impurities from the selected salvia miltiorrhiza medicinal material, crushing, extracting with water, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30, or removing impurities from the selected salvia miltiorrhiza medicinal material, crushing, extracting with 50% (V/V) ethanol under reflux for 1-3 times, each time for 0.5h, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
Pseudo-ginseng extract: removing impurities from the selected panax notoginseng, crushing, extracting with water, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30, or preparing the panax notoginseng extract by adopting the following method: removing impurities from selected pseudo-ginseng medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing each time for 0.5h, decoloring a concentrated solution by using activated carbon, and concentrating the decolored concentrated solution into an extract with the relative density of 1.10-1.30.
South Africa leaf extract: removing impurities from the selected south African leaf medicinal materials, crushing, carrying out water extraction, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30, or removing impurities from the selected south African leaf medicinal materials, crushing, carrying out reflux extraction with 50% (V/V) ethanol for 1-3 times, each time for 0.5h, decoloring the concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
Base for toothpaste: purchased directly from the market.
Example 1
Weighing 3 parts of poria extract, 0.5 part of salvia extract, 0.5 part of pseudo-ginseng extract, 0.5 part of south Africa leaf extract and 88 parts of toothpaste matrix, uniformly mixing, homogenizing in a vacuum paste making machine, and filling to obtain the toothpaste.
The matrix for the toothpaste comprises the following components in parts by weight: 15 parts of calcium hydrophosphate dihydrate, 5 parts of glycerol, 1 part of sodium dodecyl sulfate, 0.5 part of sodium alginate, 0.2 part of cane sugar, 0.2 part of perilla oil, 0.1 part of p-hydroxybenzoate, 10 parts of deionized water and 0.1 part of green edible pigment.
Example 2
Weighing 9 parts of poria extract, 1.5 parts of salvia extract, 1.5 parts of pseudo-ginseng extract, 1.5 parts of south Africa leaf extract and 96 parts of toothpaste matrix, uniformly mixing, homogenizing in a vacuum paste making machine, and filling to obtain the toothpaste.
The matrix for the toothpaste comprises the following components in parts by weight: 45 parts of anhydrous calcium hydrophosphate, 30 parts of sorbitol, 5 parts of methyl cocoa ester-based sodium taurate, 2.5 parts of carboxymethyl cellulose, 2 parts of xylitol, 1.5 parts of peppermint oil, 0.3 part of sodium benzoate, 30 parts of deionized water and 1 part of green edible pigment.
Example 3
Weighing 5 parts of poria extract, 0.7 part of salvia extract, 0.7 part of pseudo-ginseng extract, 0.7 part of south Africa leaf extract and 90 parts of toothpaste matrix, uniformly mixing, homogenizing in a vacuum paste making machine, and filling to obtain the toothpaste.
The matrix for the toothpaste comprises the following components in parts by weight: 20 parts of anhydrous silicon dioxide, 10 parts of propylene glycol, 2 parts of sodium dodecyl sulfate, 1 part of hydroxyethyl cellulose, 0.3 part of saccharin, 0.5 part of spearmint oil, 0.2 part of potassium sorbate, 15 parts of deionized water and 0.5 part of green edible pigment.
Example 4
Weighing 7 parts of poria extract, 1.2 parts of salvia extract, 1.2 parts of pseudo-ginseng extract, 1.2 parts of south Africa leaf extract and 94 parts of toothpaste matrix, uniformly mixing, homogenizing in a vacuum paste making machine, and filling to obtain the toothpaste.
The matrix for the toothpaste comprises the following components in parts by weight: 30 parts of calcium hydrophosphate dihydrate, 20 parts of propylene glycol, 3 parts of sodium dodecyl sulfate, 2 parts of carboxymethyl cellulose, 0.5 part of cane sugar, 1 part of peppermint oil, 0.3 part of sorbitol, 22 parts of deionized water and 0.8 part of green food pigment.
Example 5
Weighing 6 parts of poria extract, 1 part of salvia extract, 1 part of panax notoginseng extract, 1 part of south Africa leaf extract and 92 parts of toothpaste matrix, uniformly mixing, homogenizing in a vacuum paste making machine, and filling to obtain the toothpaste.
The matrix for the toothpaste comprises the following components in parts by weight: 50 parts of calcium hydrophosphate dihydrate, 32 parts of glycerol, 2 parts of sodium dodecyl sulfate, 1 part of carboxymethyl cellulose, 0.2 part of cane sugar, 0.2 part of peppermint oil, 0.1 part of p-hydroxybenzoate, 6.4 parts of deionized water and 0.1 part of green food pigment.
Comparative example 1
Common toothpaste without traditional Chinese medicine extracts in the existing market is selected.
Examples of the experiments
1. Experimental materials: example 1, example 2, example 3, example 4, example 5 and comparative example 1.
2. Subject: 120 patients suffering from symptoms of deficiency of both heart and spleen and oral inflammation were selected and randomly divided into six groups of 20 persons, and the toothpastes prepared in example 1, example 2, example 3, example 4, example 5 and comparative example 1 were used, respectively.
3. The experimental method comprises the following steps: the teeth are brushed once in the morning and at night every day, 3-5 min is carried out each time, the oral cavity product is continuously used for 15 days, other oral cavity products are not needed, and the change of the heart-spleen deficiency symptom and the oral inflammation of the patient before and after use is observed, so that the improvement rate of the heart-spleen deficiency symptom and the oral inflammation of the patient after the product is used is obtained.
4. The experimental results are as follows: the specific experimental results are shown in Table 1 below
TABLE 1 improvement rate of deficiency of both heart and spleen and stomatitis in each group after experiment
Group of Improvement rate of symptoms due to deficiency of both the Heart and spleen (%) Oral inflammation improvement Rate (%)
Example 1 80 75
Example 2 85 80
Example 3 90 86
Example 4 87 89
Example 5 95 92
Comparative example 1 0 25
As can be seen from table 1, the products obtained in examples 1, 2, 3, 4 and 5 all improved the symptoms of deficiency of both heart and spleen and oral inflammation of the user, with the best effect of example 5.
In conclusion, the traditional Chinese medicine toothpaste prepared by the invention has the advantages that the poria cocos is added in the raw materials, is sweet and light in taste, has a neutral nature, has the functions of promoting diuresis and excreting dampness, tonifying spleen and calming heart, can be commonly used for treating symptoms such as edema and oliguria, phlegm and fluid retention and dizziness and palpitation, spleen deficiency and poor appetite, loose stool and diarrhea, uneasiness, palpitation and insomnia and the like, and has an important nourishing effect; the formula of the invention is added with Chinese herbal medicine active ingredients of salvia miltiorrhiza and pseudo-ginseng, wherein the salvia miltiorrhiza is bitter in taste and slightly cold, and has the effects of activating blood and dissolving stasis, stimulating menstrual flow and relieving pain, clearing away heart-fire and relieving restlessness, cooling blood and eliminating carbuncle; the radix notoginseng is warm in nature and pungent in taste, has remarkable effects of promoting blood circulation to remove blood stasis, relieving swelling and relieving pain, is prepared from the radix salviae miltiorrhizae and the radix notoginseng according to the theory of traditional Chinese medicine, and has the effect of treating both symptoms and root causes for heart-spleen deficiency diseases; the south Africa leaf extract is added in the formula, is bitter and cold in nature, and has the effects of clearing heat and removing toxicity, eliminating dampness and killing insects and protecting gingiva; the medicine is dissolved into saliva by a user through daily tooth brushing, and is permeated, diffused and absorbed through oral mucosa, sublingual capillary vessels and meridian points, the damage of gastrointestinal tracts, liver and kidney to the medicine is avoided, the medicine directly enters blood circulation, the medicine is used for replacing patients with heart-spleen deficiency diseases to take for a long time, meanwhile, the stomatitis is improved, and the medicine has the advantages of multiple effects and remarkable health care effect.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (10)

1. The multifunctional traditional Chinese medicine toothpaste is characterized by comprising the following components in parts by weight: 3-9 parts of poria cocos extract, 0.5-1.5 parts of salvia miltiorrhiza extract, 0.5-1.5 parts of pseudo-ginseng extract, 0.5-1.5 parts of south Africa leaf extract and 88-96 parts of toothpaste matrix;
the matrix for the toothpaste comprises the following components in parts by weight: 15-50 parts of an abrasive agent, 5-35 parts of a humectant, 1-5 parts of a foaming agent, 0.5-3 parts of a thickening agent, 0-1 part of a sweetening agent, 0-2 parts of a spice, 0-0.5 part of a preservative, 1-40 parts of deionized water and 0-1.5 parts of an edible pigment.
2. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the abrasive is selected from one or more of dibasic calcium phosphate dihydrate, anhydrous dibasic calcium phosphate, calcium pyrophosphate, anhydrous silica, calcite powder, and chlorite;
the humectant is selected from one or more of glycerol, sorbitol, propylene glycol and polyethylene glycol;
the foaming agent is selected from one or more of sodium dodecyl sulfate, N-lauroyl sarcosine sodium, methyl cocoyl sodium taurate and acyl sodium glutamate;
the thickening agent is selected from one or more of sodium alginate, carboxymethyl cellulose, hydroxyethyl cellulose, xanthan gum powder and hydroxypropyl guar gum;
the sweetener is one or more selected from sucrose, saccharin, sodium cyclamate, xylitol and sodium diaminate;
the spice is selected from one or more of perilla oil, peppermint oil, lemon oil, spearmint oil, orange oil, wintergreen oil, clove oil, cinnamon oil, anise oil, menthol, borneol, citral, laurylaldehyde, vanillin and amyl acetate;
the preservative is selected from one or more of p-hydroxybenzoate, sodium benzoate, potassium sorbate and sorbitol;
the deionized water is a gel-forming dispersion medium of the toothpaste;
the edible pigment is green or purple.
3. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the poria cocos extract is prepared by the following method: removing impurities from the selected poria cocos medicinal materials, crushing, extracting with water, decoloring a concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
4. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the poria cocos extract can be further prepared by the following method: removing impurities from the selected poria cocos medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing extraction for 0.5 hour each time, decoloring a concentrated solution by using activated carbon, and concentrating the decolored concentrated solution into an extract with the relative density of 1.10-1.30.
5. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the red sage root extract is prepared by the following method: removing impurities from a carefully selected salvia miltiorrhiza medicinal material, crushing, extracting with water, decoloring a concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
6. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the salvia miltiorrhiza extract can be prepared by the following method: removing impurities from a selected salvia miltiorrhiza medicinal material, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, wherein each time is 0.5h, and concentrating a concentrated solution after decoloring by using activated carbon into an extract with the relative density of 1.10-1.30.
7. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the notoginseng extract is prepared by the following method: removing impurities from the selected pseudo-ginseng medicinal materials, crushing, extracting with water, decoloring a concentrated solution with activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
8. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the notoginseng extract can be further prepared by the following method: removing impurities from selected pseudo-ginseng medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing each time for 0.5h, decoloring a concentrated solution by using activated carbon, and concentrating the decolored concentrated solution into an extract with the relative density of 1.10-1.30.
9. The multifunctional traditional Chinese medicine toothpaste according to claim 1, wherein the south Africa leaf extract is prepared by the following method: removing impurities from a selected south Africa leaf medicinal material, crushing, carrying out water extraction, decoloring a concentrated solution by using activated carbon, and concentrating into an extract with the relative density of 1.10-1.30;
the south Africa leaf can also be prepared by adopting the following method: removing impurities from the selected south Africa leaf medicinal materials, crushing, performing reflux extraction for 1-3 times by using 50% (V/V) ethanol, performing each time for 0.5h, decoloring the concentrated solution by using activated carbon, and concentrating into an extract with the relative density of 1.10-1.30.
10. The preparation method of the multifunctional traditional Chinese medicine toothpaste according to any one of claims 1 to 9, wherein the specific preparation method of the traditional Chinese medicine toothpaste comprises the following steps:
s1: preparing raw materials: preparing Poria extract, Saviae Miltiorrhizae radix extract, Notoginseng radix extract and folium Africae extract;
s2: weighing raw materials: weighing the required weight parts of tuckahoe extract, salvia miltiorrhiza extract, panax notoginseng extract, south Africa leaf extract and toothpaste matrix according to the mixture ratio requirement;
s3: mixing and filling: mixing the above weighed Poria extract, Saviae Miltiorrhizae radix extract, Notoginseng radix extract, folium Africae extract and toothpaste matrix, homogenizing in vacuum paste making machine, and packaging.
CN201911096824.2A 2019-11-11 2019-11-11 Multifunctional traditional Chinese medicine toothpaste and preparation method thereof Pending CN112315856A (en)

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