CN105434263A - Chinese herbal medicine toothpaste - Google Patents

Chinese herbal medicine toothpaste Download PDF

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Publication number
CN105434263A
CN105434263A CN201510966144.7A CN201510966144A CN105434263A CN 105434263 A CN105434263 A CN 105434263A CN 201510966144 A CN201510966144 A CN 201510966144A CN 105434263 A CN105434263 A CN 105434263A
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parts
filtrate
fructus mume
chinese herbal
toothpaste
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杨秀英
邱敏蓉
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Nanchang Institute of Technology
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Nanchang Institute of Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/31Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
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Abstract

The invention relates to Chinese herbal medicine toothpaste, and especially relates to toothpaste containing extractives of flos sophorae, cortex magnoliae officinalis, flos lonicerae, herba lycopi, rhizoma atractylodis, fructus mume and cablin patchouli herb, and a preparation method for the toothpaste. The toothpaste comprises the following compositions in parts by mass: 10-13 parts of flos sophorae, 15-17 parts of cortex magnoliae officinalis, 3 parts of flos lonicerae, 1.5 parts of herba lycopi, 3 parts of rhizoma atractylodis, 15-20 parts of fructus mume, 7 parts of cablin potchouli herb, 7-10 parts of silicon dioxide, 1-3 parts of hydroxyethyl cellulose, 8-11 parts of glycerin, 0.15 part of xylitol, 0.25 part of herba menthae essential oil, and 90-100 parts of water. The toothpaste is capable of effectively treating oral cavity diseases and restoring oral cavity damage, the Chinese herbal medicine extraction technology is simple, and manufacture cost is low.

Description

A kind of Chinese herbal toothpaste
Technical field
The present invention relates to a kind of Chinese herbal toothpaste, the toothpaste particularly containing Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Fructus Mume, Herba Pogostemonis extract, and preparation method thereof.
Background technology
At present, toothpaste kind based on Chinese herbal medicine is a lot, similar YUNNAN BAIYAO, Radix Zanthoxyli, Radix Notoginseng etc., for preventing decayed tooth and treatment oral disease, there is good curative effect, but because production cost is higher, because price is also generally higher, be difficult to allow consumers in general accept, therefore also have the toothpaste containing a small amount of medicinal herb components, similar Crest, Chinese toothpaste etc., although production cost is low, drug effect also can be slow simultaneously, life-time service can have the effect of prevention oral disease, but for treatment oral disease, curative effect is not clearly.
Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Fructus Mume, Herba Pogostemonis is all common Chinese herbal medicine, not only cheap, and their effect have also been obtained proof in practice, often as anti-inflammation, repair the drug uses such as damage, and in " legendary god of farming's BAICAO warp ", there is their record, describe Flos Sophorae extract in Chinese patent 201310228040.7 " novelty teabag of Desmodium caudatum (Thunb.) DC. extract and extracting method and extract " and also there is blood coagulation resisting function, also effect of Cortex Magnoliae Officinalis anti-caries was mentioned in Chinese patent 201210583357.8 " a kind of Chinese herbal medicine mouthwash " and Chinese patent 01106513.3 " caries preventing Magnolia Officinalis toothpaste ", total institute is known, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis have bactericidal antiphlogistic drug effect, and also refer to them in Chinese patent 201410045136.4 " a kind of composite plant disinfectant and preparation method thereof " there is good antibacterial and bacteriostasis efficacy, the drug effect that Chinese patent 201210580735.7 " antitoxin bacterium and preparation method thereof " refer to Fructus Mume, the repair cell of Herba Pogostemonis damages.These Chinese herbal medicine all have the drug effect of various uniqueness, and researching value is high, also have much at present to their respective research, but pharmacodynamic properties in conjunction with them is rare for the research being made into toothpaste.
Summary of the invention
For overcoming the above problems, the object of this invention is to provide a kind of Chinese herbal toothpaste, effectively can treat oral disease and promoting that oral cavity breakage is repaired.
Another object of the present invention is to provide a kind of preparation method of Chinese herbal toothpaste, and extraction process is simple, and cost is low.
Another object of the present invention is to provide the application of a kind of Chinese herbal toothpaste in treatment oral disease and reparation oral cavity breakage.
Technical scheme of the present invention is:
A kind of Chinese herbal toothpaste, comprises Flos Sophorae 10-13 part, Cortex Magnoliae Officinalis 15-17 part, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 15-20 part, Herba Pogostemonis 7 parts, silicon dioxide 7-10 part, hydroxyethyl-cellulose 1-3 part, glycerol 8-11 part, xylitol 0.15 part, Herba Menthae Oleum sesami 0.25 part, water 90-100 part in mass ratio in its composition.
A kind of Chinese herbal toothpaste, wherein Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Herba Pogostemonis adopts water boiling and extraction method, respectively by Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis is put into dismembyator and pulverizes, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1-2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decoct after 20 minutes, 70 DEG C decoct 1h again, filter, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.05-1.1, obtain said herbal medicine powdered extract.
A kind of Chinese herbal toothpaste, wherein Fructus Mume extracting method is, extracts Fructus Mume juice, then be separated by centrifuge by the Fructus Mume juice of collection with juice extractor, filters, and collect filtrate, being concentrated into relative density is 1.05-1.1, obtains powdered Fructus Mume extract.
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1-2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.05-1.1, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.05-1.1, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 1-3 part, glycerol 8-11 part, Herba Menthae Oleum sesami 0.25 part, water 90-100 part, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, Flos Sophorae 10-13 part, Cortex Magnoliae Officinalis 15-17 part, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 15-20 part, Herba Pogostemonis 7 parts, and silicon dioxide 7-10 part, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Advantage of the present invention is:
1. Chinese herbal medicine extracting technique is simple, and cost is low;
2. obtained toothpaste effectively can treat oral disease;
3. obtained toothpaste can promote that oral cavity breakage is repaired.
Detailed description of the invention
Embodiment 1
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.05, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge high speed centrifugation by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.08, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 1.5 parts, glycerol 10 parts, Herba Menthae Oleum sesami 0.25 part, 95 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, 11 parts, Flos Sophorae, Cortex Magnoliae Officinalis 16 parts, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 18 parts, Herba Pogostemonis 7 parts, and silicon dioxide 8 parts, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Embodiment 2
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.1, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge high speed centrifugation by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.05, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 1 part, glycerol 11 parts, Herba Menthae Oleum sesami 0.25 part, 100 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, 10 parts, Flos Sophorae, Cortex Magnoliae Officinalis 17 parts, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 15 parts, Herba Pogostemonis 7 parts, and silica 10 part, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Embodiment 3
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1.5h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.08, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge high speed centrifugation by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.1, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 3 parts, glycerol 8 parts, Herba Menthae Oleum sesami 0.25 part, 90 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, 13 parts, Flos Sophorae, Cortex Magnoliae Officinalis 15 parts, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 20 parts, Herba Pogostemonis 7 parts, and silicon dioxide 7 parts, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Embodiment 4
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.07, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.06, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 2 parts, glycerol 9 parts, Herba Menthae Oleum sesami 0.25 part, 95 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, 9 parts, Flos Sophorae, Cortex Magnoliae Officinalis 14 parts, Flos Lonicerae 2 parts, Herba Lycopi 1 part, Rhizoma Atractylodis 2 parts, Fructus Mume 14 parts, Herba Pogostemonis 6 parts, and silicon dioxide 9 parts, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Embodiment 5
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.08, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.09, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 3 parts, glycerol 10 parts, Herba Menthae Oleum sesami 0.25 part, 100 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, 14 parts, Flos Sophorae, Cortex Magnoliae Officinalis 18 parts, Flos Lonicerae 4 parts, Herba Lycopi 2 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 21 parts, Herba Pogostemonis 8 parts, and silica 10 part, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Embodiment 6
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then add the distilled water of Chinese herbal medicine quality 3 times, 100 DEG C decoct after 1 hour, 70 DEG C decoct 2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.07, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.09, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 1 part, glycerol 9 parts, Herba Menthae Oleum sesami 0.25 part, 95 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 17 parts, Herba Pogostemonis 7 parts, and silicon dioxide 8 parts, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
Embodiment 7
Random selection suffers from the patient of oral disease, totally 247 people, wherein oral ulcer patient 109 people, patients with periodontitis 72, eurodonticus 66 people, participates in the patient of experiment, is divided into 7 groups at random, wherein 1-6 group uses the toothpaste obtained by embodiment 1-6,7 groups use conventional toothpaste, sooner or later each brush tooth, brushing time 3-5 minute, warm water is gargled, and experimental period is one month;
Potent: disease disappears, without sense of discomfort;
Effective: disease alleviates, slightly sense of discomfort;
Invalid: disease is unchanged or increase the weight of;
The toothpaste obtained by embodiment 1-3 that conclusion: group number 1-3 uses, its component and content are all within the scope of the invention, contrast group number 7, visible, there is better effect to oral disease effect, wherein embodiment 1 is optimal case, the toothpaste obtained by embodiment 4-6 that group number 4-6 uses, its component or content, not within the scope of the invention, contrast group number 7, visible, action effect declines.
Embodiment 8
Damaged patient 40 people in random selecting oral cavity, and all do not have oral disease history, be divided into 2 groups, wherein 1 group uses conventional toothpaste, and another group uses the toothpaste obtained by embodiment 1, participates in experimenter and does not all take medicine, breakage heals completely, be then recovery from illness, counting use time, experimental result is as follows:
Conclusion: contrast visible, than conventional toothpaste, toothpaste prepared by the present invention promotes that oral cavity breakage is repaired faster.

Claims (5)

1. a Chinese herbal toothpaste, is characterized in that: comprise Flos Sophorae 10-13 part, Cortex Magnoliae Officinalis 15-17 part, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 15-20 part, Herba Pogostemonis 7 parts, silicon dioxide 7-10 part, hydroxyethyl-cellulose 1-3 part, glycerol 8-11 part, xylitol 0.15 part, Herba Menthae Oleum sesami 0.25 part, water 90-100 part in its composition in mass ratio.
2. a kind of Chinese herbal toothpaste according to claim 1, it is characterized in that: wherein Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Herba Pogostemonis adopts water boiling and extraction method, respectively by Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis is put into dismembyator and pulverizes, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1-2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decoct after 20 minutes, 70 DEG C decoct 1h again, filter, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.05-1.1, obtain said herbal medicine powdered extract.
3. a kind of Chinese herbal toothpaste according to claim 1, it is characterized in that: wherein Fructus Mume extracting method is, Fructus Mume juice is extracted with juice extractor, again the Fructus Mume juice of collection is separated by centrifuge, filter, collect filtrate, being concentrated into relative density is 1.05-1.1, obtains powdered Fructus Mume extract.
4. a kind of Chinese herbal toothpaste according to claim 1, is characterized in that:
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1-2h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.05-1.1, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.05-1.1, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 1-3 part, glycerol 8-11 part, Herba Menthae Oleum sesami 0.25 part, water 90-100 part, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, Flos Sophorae 10-13 part, Cortex Magnoliae Officinalis 15-17 part, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 15-20 part, Herba Pogostemonis 7 parts, and silicon dioxide 7-10 part, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
5. a kind of Chinese herbal toothpaste according to claim 4, is characterized in that:
A kind of preparation method of Chinese herbal toothpaste:
(1) respectively Flos Sophorae, Cortex Magnoliae Officinalis, Flos Lonicerae, Herba Lycopi, Rhizoma Atractylodis, Herba Pogostemonis are put into dismembyator and pulverize, then the distilled water of Chinese herbal medicine quality 3 times is added, 100 DEG C decoct after 1 hour, 70 DEG C decoct 1h again after, filter, collect the first filtrate and filtering residue, filtering residue is added again the water of medicinal residues quality 2 times, 100 DEG C decocted after 20 minutes, and 70 DEG C decoct 1h again, filtered, collect the second filtrate, after the first filtrate and the mixing of the second filtrate, being concentrated into relative density is 1.05, obtains said herbal medicine powdered extract;
(2) extract Fructus Mume juice with juice extractor, then be separated by centrifuge high speed centrifugation by the Fructus Mume juice of collection, filter, collect filtrate, being concentrated into relative density is 1.08, obtains powdered Fructus Mume extract;
(3) by hydroxyethyl-cellulose 1.5 parts, glycerol 10 parts, Herba Menthae Oleum sesami 0.25 part, 95 parts, water, put into glue pot, stir, then add xylitol 0.15 part, be stirred to translucent, then leave standstill 1h, then add above-mentioned obtained dry powder, 11 parts, Flos Sophorae, Cortex Magnoliae Officinalis 16 parts, Flos Lonicerae 3 parts, Herba Lycopi 1.5 parts, Rhizoma Atractylodis 3 parts, Fructus Mume 18 parts, Herba Pogostemonis 7 parts, and silicon dioxide 8 parts, stir 1h, obtain mastic, after again mastic being ground by grinder, obtained toothpaste.
CN201510966144.7A 2015-12-22 2015-12-22 Chinese herbal medicine toothpaste Pending CN105434263A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929167A (en) * 2017-12-27 2018-04-20 嘉兴神木龙香林业有限公司 A kind of Chinese medicinal toothpaste
CN113171320A (en) * 2021-05-08 2021-07-27 广州市盛龙口腔清洁用品有限公司 Plant-flavor toothpaste and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107929167A (en) * 2017-12-27 2018-04-20 嘉兴神木龙香林业有限公司 A kind of Chinese medicinal toothpaste
CN113171320A (en) * 2021-05-08 2021-07-27 广州市盛龙口腔清洁用品有限公司 Plant-flavor toothpaste and preparation method thereof

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Application publication date: 20160330