CN109419948A - A kind of Chinese medicine tooth-protective chewing gum and preparation method thereof - Google Patents

A kind of Chinese medicine tooth-protective chewing gum and preparation method thereof Download PDF

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CN109419948A
CN109419948A CN201710745680.3A CN201710745680A CN109419948A CN 109419948 A CN109419948 A CN 109419948A CN 201710745680 A CN201710745680 A CN 201710745680A CN 109419948 A CN109419948 A CN 109419948A
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chewing gum
chinese medicine
tooth
protective
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陈璇
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The present invention relates to a kind of Chinese medicine tooth-protective chewing gums, espespecially a kind of Chinese medicine tooth-protective chewing gum and preparation method thereof, the Chinese medicine tooth-protective chewing gum is mainly made of following raw material: Radix Glycyrrhizae, the root of Dahurain angelica, peppermint, cloves, Chinese gall, the sterculia seed, aloe, vanilla, donkey-hide gelatin；The extracting solution of Chinese medicine draft medicinal material is added in chewing gum by chewing gum of the invention, is suitable for and is taken generation, can be carried out cleaning and health care to oral cavity whenever and wherever possible, can be prevented, treated and protect the tooth of people, is kept its implication awake, is reduced the situation of gum, tooth meat bleeding；The binding ability of active constituent and streptococcus mutans in chewing gum is stronger, can be directly entered in streptococcus mutans cell body to play the role of killing bacterium.

Description

A kind of Chinese medicine tooth-protective chewing gum and preparation method thereof
Technical field
The present invention relates to a kind of food processing technology field, especially a kind of Chinese medicine tooth-protective chewing gum and preparation method thereof.
Background technique
There is investigation to show, Chinese's oral healthy condition allows of no optimist, and caries incidence in all parts of the country is 49.88%；Due to being permitted The oral health of more people is realized weak, and 90% or more eurodonticus not yet carried out regular examination of mouth and treatment, and children The ratio for suffering from dental caries is more up to 80% or more, with World Health Organization's target phase of 90% children without saprodontia proposed in 2001 Away from very remote.
Saprodontia is primarily referred to as object containing confectionery under streptococcus mutans effect when generation glycolysis, and generated acid acts on tooth Tooth, so that enamel and dentine are destroyed.Anti-caries product applied currently on the market is roughly divided into following a few classes: one for containing Fluoride preparation, anti-caries raw material are to promote tooth calcification, reduce sour corrosion, this is indirectly-acting, offer limited effectiveness；Second is that antibacterial The application of drug, such as the calm and peaceful Iodophor of mouth, the main component of mouth Thailand is that substances, the mouth Thailands such as chlorohexidene, metronidazole, glycerol can be adsorbed on The surface of enamel, mucous membrane of mouth and plaque, and slow release have great broad-spectrum antibacterial, bactericidal effect, and can prevent The only generation of mouth infection, but be used for a long time and will lead to the side effects such as tooth turns yellow, the sense of taste changes.
Summary of the invention
The invention aims to provide a kind of Chinese medicine tooth-protective chewing gum and preparation method thereof.
The present invention is achieved by the following technical programs:
1, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that be made of following raw material: 2-6 parts of Radix Glycyrrhizae, 3-7 parts of the root of Dahurain angelica, 5-10 parts of peppermint, 2-8 parts of cloves, 4-7 parts of Chinese gall, 3-6 parts of the sterculia seed, 6-12 parts of aloe, 6-10 parts of vanilla, donkey-hide gelatin 9-12 Part；
2, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that include the following steps and be made:
(1) 2-6 parts of Radix Glycyrrhizae, 3-7 parts of the root of Dahurain angelica, 5-10 parts of peppermint, 2-8 parts of cloves are cleaned 2-3 times repeatedly with clear water, after cleaning It drains, is then dried 2 to 4 hours at 70-75 DEG C, make moisture up to 3-5%, smash it through 40 meshes, 6-8 times of body is added in filter residue Product concentration is 80% ethyl alcohol, continues reflux 1-3 hours, filters off residue and collects extracting solution, extracting solution is condensed into density 1.05- 1.08g/cm3 medicinal extract；
(2) by 4-7 parts of Chinese gall, 3-6 parts of the sterculia seed, 6-12 parts of aloe, 6-10 parts of vanilla, 9-12 parts of donkey-hide gelatin crushing, add water logging Bubble, decocts 1-3 times at 85-95 DEG C, decocts 1-2h every time, merges decoction liquor, filtering, and ethanol precipitation is added in filtrate, and it is heavy to filter off It forms sediment, relative density is the medicinal extract of 1.05-1.15 when being concentrated under reduced pressure into 60 DEG C；
(3) by the medicinal extract of step (1) and step (2) mix to get；
3, a kind of Chinese medicine tooth-protective chewing gum, it is characterised in that.The sterculia seed and aloe must first be enucleated, remove the peel.
The invention has the following advantages:
The binding ability of active constituent and streptococcus mutans in Chinese medicine tooth-protective chewing gum of the invention is stronger, can be directly entered change To play the role of killing bacterium in shape Streptococcal cells body；Active constituent of the invention is Chinese medical extract, has property Mildly, small, the safe and non-toxic advantage of irritation can be eaten for a long time.
Specific embodiment:
Below with reference to embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited to implement The range that example indicates.
Embodiment 1
1, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that be made of following raw material: 2-6 parts of Radix Glycyrrhizae, 3-7 parts of the root of Dahurain angelica, 5-10 parts of peppermint, 2-8 parts of cloves, 4-7 parts of Chinese gall, 3-6 parts of the sterculia seed, 6-12 parts of aloe, 6-10 parts of vanilla, donkey-hide gelatin 9-12 Part；
2, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that include the following steps and be made:
(1) 2 parts of Radix Glycyrrhizae, 3 parts of the root of Dahurain angelica, 5 parts of peppermint, 2 parts of cloves are cleaned 2 times repeatedly with clear water, is drained after cleaning, then 70 It DEG C dries 2 hours, makes moisture up to 3%, smash it through 40 meshes, the volumetric concentration that 6 times are added in filter residue is 80% ethyl alcohol, is continued back Stream 1 hour filters off residue and collects extracting solution, extracting solution is condensed into the medicinal extract of density 1.05g/cm3；
(2) it by 4 parts of Chinese gall, 3 parts of the sterculia seed, 6 parts of aloe, 6 parts of vanilla, 9 parts of donkey-hide gelatin crushing, soaks in water, is decocted at 85 DEG C It boils 1 time, decocts 1h every time, merge decoction liquor, filtering, ethanol precipitation is added in filtrate, filters off precipitating, is concentrated under reduced pressure into 60 DEG C of phases The medicinal extract for being 1.05 to density；
(3) by the medicinal extract of step (1) and step (2) mix to get；
3, a kind of Chinese medicine tooth-protective chewing gum, it is characterised in that.The sterculia seed and aloe must first be enucleated, remove the peel.
Embodiment 2
1, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that be made of following raw material: 2-6 parts of Radix Glycyrrhizae, 3-7 parts of the root of Dahurain angelica, 5-10 parts of peppermint, 2-8 parts of cloves, 4-7 parts of Chinese gall, 3-6 parts of the sterculia seed, 6-12 parts of aloe, 6-10 parts of vanilla, donkey-hide gelatin 9-12 Part；
2, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that include the following steps and be made:
(1) 4 parts of Radix Glycyrrhizae, 5 parts of the root of Dahurain angelica, 8 parts of peppermint, 5 parts of cloves are cleaned 2 times repeatedly with clear water, is drained after cleaning, then 73 It DEG C dries 3 hours, makes moisture up to 4%, smash it through 40 meshes, the volumetric concentration that 7 times are added in filter residue is 80% ethyl alcohol, is continued back Stream 5 hours filters off residue and collects extracting solution, extracting solution is condensed into the medicinal extract of density 1.07g/cm3；
(2) it by 5 parts of Chinese gall, 5 parts of the sterculia seed, 8 parts of aloe, 8 parts of vanilla, 10 parts of donkey-hide gelatin crushing, soaks in water, is decocted at 90 DEG C It boils 2 times, decocts 2h every time, merge decoction liquor, filtering, ethanol precipitation is added in filtrate, filters off precipitating, is concentrated under reduced pressure into 60 DEG C of phases The medicinal extract for being 1.10 to density；
(3) by the medicinal extract of step (1) and step (2) mix to get；
3, a kind of Chinese medicine tooth-protective chewing gum, it is characterised in that.The sterculia seed and aloe must first be enucleated, remove the peel.
Embodiment 3
1, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that be made of following raw material: 2-6 parts of Radix Glycyrrhizae, 3-7 parts of the root of Dahurain angelica, 5-10 parts of peppermint, 2-8 parts of cloves, 4-7 parts of Chinese gall, 3-6 parts of the sterculia seed, 6-12 parts of aloe, 6-10 parts of vanilla, donkey-hide gelatin 9-12 Part；
2, a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that include the following steps and be made:
(1) 6 parts of Radix Glycyrrhizae, 7 parts of the root of Dahurain angelica, 10 parts of peppermint, 8 parts of cloves are cleaned 3 times repeatedly with clear water, drains after cleaning, then exists 75 DEG C are dried 4 hours, are made moisture up to 5%, are smashed it through 40 meshes, and the volumetric concentration that 8 times are added in filter residue is 80% ethyl alcohol, is continued Reflux 3 hours filters off residue and collects extracting solution, extracting solution is condensed into the medicinal extract of density 1.08g/cm3；
(2) it by 7 parts of Chinese gall, 6 parts of the sterculia seed, 12 parts of aloe, 10 parts of vanilla, 12 parts of donkey-hide gelatin crushing, soaks in water, at 95 DEG C It decocts 3 times, decocts 2h every time, merge decoction liquor, filtering, ethanol precipitation is added in filtrate, precipitating is filtered off, when being concentrated under reduced pressure into 60 DEG C The medicinal extract that relative density is 1.15；
(3) by the medicinal extract of step (1) and step (2) mix to get；
3, a kind of Chinese medicine tooth-protective chewing gum, it is characterised in that.The sterculia seed and aloe must first be enucleated, remove the peel.
The above content is a further detailed description of the present invention in conjunction with specific preferred embodiments, and it cannot be said that Specific implementation of the invention is only limited to these instructions.For those of ordinary skill in the art to which the present invention belongs, exist Under the premise of not departing from present inventive concept, a number of simple deductions or replacements can also be made, all shall be regarded as belonging to of the invention Protection scope.

Claims (4)

1. a kind of Chinese medicine tooth-protective chewing gum, which is characterized in that be made of following raw material: 2-6 parts of Radix Glycyrrhizae, 3-7 parts of the root of Dahurain angelica, 5-10 parts of peppermint, 2-8 parts of cloves, 4-7 parts of Chinese gall, 3-6 parts of the sterculia seed, 6-12 parts of aloe, 6-10 parts of vanilla, donkey-hide gelatin 9-12 Part.
2. a kind of Chinese medicine tooth-protective chewing gum according to claim 1, which is characterized in that include the following steps and be made: (1) will Radix Glycyrrhizae, the root of Dahurain angelica, peppermint, cloves are cleaned 2-3 times repeatedly with clear water, drain after cleaning, and then at 70-75 DEG C, dry 2 to 4 hours, Make moisture up to 3-5%, smash it through 40 meshes, the volumetric concentration that 6-8 times is added in filter residue is 80% ethyl alcohol, and it is small to continue reflux 1-3 When, it filters off residue and collects extracting solution, extracting solution is condensed into the medicinal extract that density is 1.05-1.08g/cm3；
(2) Chinese gall, the sterculia seed, aloe, vanilla, donkey-hide gelatin are crushed, soaks in water, decoct 1-3 times at 85-95 DEG C, every time 1-2h is decocted, decoction liquor, filtering are merged, ethanol precipitation is added in filtrate, filters off precipitating, relative density is when being concentrated under reduced pressure into 60 DEG C 1.05-1.15 medicinal extract；(3) by the medicinal extract of step (1) and step (2) mix to get.
3. a kind of Chinese medicine tooth-protective chewing gum according to claim 1, it is characterised in that.
The sterculia seed and aloe described in 4. must first be enucleated, remove the peel.
CN201710745680.3A 2017-08-26 2017-08-26 A kind of Chinese medicine tooth-protective chewing gum and preparation method thereof Pending CN109419948A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021052551A3 (en) * 2019-09-17 2021-05-27 محمود جلال، Gum base and safe, natural oral composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103404685A (en) * 2013-08-26 2013-11-27 贵州省健康茶科技有限公司 Tooth-protecting chewing gum
CN103535499A (en) * 2013-09-22 2014-01-29 王爽 Chewing gum
CN104095929A (en) * 2014-07-29 2014-10-15 桂林实力科技有限公司 Decayed-tooth-resistant chewing gum
CN106858028A (en) * 2017-02-17 2017-06-20 上海市第七人民医院 A kind of chewing gum comprising eclipta and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103404685A (en) * 2013-08-26 2013-11-27 贵州省健康茶科技有限公司 Tooth-protecting chewing gum
CN103535499A (en) * 2013-09-22 2014-01-29 王爽 Chewing gum
CN104095929A (en) * 2014-07-29 2014-10-15 桂林实力科技有限公司 Decayed-tooth-resistant chewing gum
CN106858028A (en) * 2017-02-17 2017-06-20 上海市第七人民医院 A kind of chewing gum comprising eclipta and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021052551A3 (en) * 2019-09-17 2021-05-27 محمود جلال، Gum base and safe, natural oral composition

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Application publication date: 20190305