CN109864966A - A kind of Chinese medicine compound prescription mouthwash and preparation method thereof - Google Patents
A kind of Chinese medicine compound prescription mouthwash and preparation method thereof Download PDFInfo
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- CN109864966A CN109864966A CN201910337774.6A CN201910337774A CN109864966A CN 109864966 A CN109864966 A CN 109864966A CN 201910337774 A CN201910337774 A CN 201910337774A CN 109864966 A CN109864966 A CN 109864966A
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Abstract
The invention discloses a kind of Chinese medicine compound prescription mouthwashes and preparation method thereof, comprise the following components in parts by weight: 1-5 parts of Yunnan Baiyao, 10-20 parts of peppermint, 5-10 parts of honey, 2-5 parts of probiotics, 10-20 parts of Siraitia grosvenorii, 5-10 parts of Radix Glycyrrhizae, 5-10 parts of the leaf of bamboo.The pain of periodontal disease generation can be effectively relieved in Chinese medicine compound prescription mouthwash of the invention, and without allergic reaction.Without adding preservative, the holding time is long, and liquid is clarified in mouthwash, and no layering and sediment are easy to use.
Description
Technical field
The present invention relates to oral care product technical fields, more particularly to a kind of Chinese medicine compound prescription mouthwash and its preparation side
Method.
Background technique
Mouthwash is the oral care implement of daily cleaning and health care in people's daily life, and the oral cavity of modern will be at any time
It keeps pure and fresh clean, but carries toothbrush with toothpaste squeezer without condition.Mouthwash be can with portable dental care products,
It can simply and easily solve the problems, such as implication.
Mouthwash drug dispensing and non-pharmacological property mouthwash, pharmacological property mouthwash are suitable for oral inflammation patient, can play anti-inflammatory and kill
The effect of bacterium.And used in most people daily life to be non-pharmacological property mouthwash, major function is to maintain implication
It is pure and fresh.Common drug physical property mouthwash is likely to result in normal flora in oral cavity and lacks of proper care, or even can cause allergic reaction.According to incomplete
Statistics, in 35 years old or more crowd, crowd's accounting with periodontal disease reaches 97%, due to the tooth-brushing habit of mistake
And bleeding gums caused by diet problem, swelling and aching of gum and gingivitis are typical periodontal disease symptoms, especially in it is old
The incidence of year crowd's periodontal disease is higher.
A kind of herbal mixture mouthwash is disclosed in patent CN105233061A, is since fresh bamboo sap, Radix zanthoxyli mention
The effect of compound Chinese herbal medicinal ingredients for taking object and Gardenoside to form are heat-clearing and fire-reducing, the sliding phlegm benefit key using fresh bamboo sap and Cape jasmine
The analgesia of sub- glycosides, cholagogue, anti-inflammatory and inhibition gastric secretion effect combine, and extract with Radix zanthoxyli common in traditional mouthwash
Object etc. combines and mouthwash is made, and can play preferably hemostasis, anti-inflammatory, analgesic effect.
A kind of solid type probiotics mouthwash and its preparation and application are disclosed in patent CN107308102A,
It mainly include pulvis filler, disintegrating agent, probiotics, prebiotics and D-lactic acid zinc.Its compared with common liquid mouthwash,
Preservative free addition, and inhibiting effect will not be generated to probiotics, while can remove halitosis, smoke etc., rapid-action, effect is strong.
But this is used using solid mouthwash powder need to be dissolved into water, can not directly be used.
Currently used medicinal mouthwash causes lamination serious, or even put since various composition is directly difficult to dissolve each other
There is phenomena such as sediment after setting a period of time, its drug effect is caused to substantially reduce, when use also needs firmly to rock mixing, causes to make
The problems such as not convenient, increasingly highlights.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine compound prescription mouthwashes.The Chinese medicine compound prescription mouthwash, in adjustable oral cavity
Biological flora, while having a good curative effect to the bleeding that generates by periodontal disease, pain, the water liquid clarification of gargling of the application,
It is generated without layering and sediment, it is easy to use.
It is a further object of the present invention to provide the preparation methods of the Chinese medicine compound prescription mouthwash.
A kind of Chinese medicine compound prescription mouthwash, comprises the following components in parts by weight: 1-5 parts of Yunnan Baiyao, 10-20 parts of peppermint, and bee
It is 5-10 parts sweet, 2-5 parts of probiotics, 10-20 parts of Siraitia grosvenorii, 5-10 parts of Radix Glycyrrhizae, 5-10 parts of the leaf of bamboo.
It preferably, further include 5-10 parts of Radix zanthoxyli ethanol extract.
Preferably, the Radix Zanthoxyli extract, which includes the following steps, is prepared:
Two sides crown block is chosen, dries, crush after cleaning；
Ethyl alcohol is added to be submerged, is evaporated under reduced pressure, collects 45-50 DEG C of fraction, as Radix zanthoxyli ethanol extract.
Preferably, the probiotics is at least one of lactobacillus fermenti, bifidobacterium lactis.
A kind of preparation method of Chinese medicine compound prescription mouthwash, comprising the following steps:
(1) peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are weighed in proportion, are broken into powder；
(2) smashed peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are mixed, water is added and carries out being cooked by slow fire 60-
120min is filtered to remove the solid dregs of a decoction after decoction；
(3) heating concentration will be carried out in the liquid medicine after decoction, being concentrated into liquor strength is 1.5%-3.5%；
(4) it will be proportionally added into honey, probiotics, Yunnan Baiyao and Radix zanthoxyli ethanol extract in the medical fluid of concentration, mixes
It closes and Chinese medicine compound prescription mouthwash is uniformly made.
Yunnan Baiyao is a kind of Chinese herbal medicine, has apparent curative effect for a variety of hemorrhagic diseases, can accelerate hemostasis, contracting
The short course of disease.Its pharmacological action mainly shortening bleeding time and clotting time, Yunnan Baiyao can be such that prothrombin time shortens, and increase
Add prothrombin content, and can induce the aggregation and release of blood platelet.Hemostasis aspect goes out wound also using very extensive
Blood, hemorrhage of digestive tract, hemorrhage in respiratory tract, hemorrhagic encephalopathy, gynaecology, paediatrics, ENT dept.'s hemorrhagic disease have to be controlled well
Therapeutic effect.Yunnan Baiyao has inhibiting effect to the release of anti-inflammatory agent, for improve microcirculation, change vasopermeability etc.
It is all effective.In treatment wound, local red and swollen heat pain can be effectively treated, activating microcirculation and removing stasis medicinal inhibits swelling.Furthermore Yunnan is white
There are also antibacterial effects for medicine, can prevent the infection of wound.Yunnan Baiyao can promote the secretion of cortex hormone of aadrenaline, for
Disease of immune system has therapeutic effect.
Contain menthol in peppermint, the substance can fresh breath, also there is antisepsis and sterilization and other effects.
Compared with prior art, the invention has the following advantages: Chinese medicine compound prescription mouthwash of the invention can effectively delay
It solves bleeding gums, swelling and aching of gum and adjusts intraoral flora, other periodontal diseases caused by prevention flora imbalance；The present invention
In combined by the way that honey is added with traditional Chinese medicinal components, it is ensured that the survival rate of probiotics, other intracavitary bacteriums of counterpart have when use
Inhibiting effect inhibits probiotics without obvious；Water liquid clarification of gargling of the invention, no layering and deposited phenomenon, greatly improve
The service performance and effect of mouthwash.
Specific embodiment
The present invention is further explained in the light of specific embodiments.
Embodiment 1
A kind of Chinese medicine compound prescription mouthwash, comprises the following components in parts by weight:
5 parts of Yunnan Baiyao, 20 parts of peppermint, 10 parts of honey, 5 parts of lactobacillus fermenti, 20 parts of Siraitia grosvenorii, 10 parts of Radix Glycyrrhizae, the leaf of bamboo
10 parts, 10 parts of Radix zanthoxyli ethanol extract, wherein Radix zanthoxyli ethanol extract includes the following steps preparation: choosing the two sides crown
Block is dried after cleaning, is crushed；Ethyl alcohol is added to be submerged, is evaporated under reduced pressure, collects 50 DEG C of fraction, as Radix zanthoxyli ethyl alcohol mentions
Take object.
The preparation method of the Chinese medicine compound prescription mouthwash, comprising the following steps:
(1) peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are weighed in proportion, are broken into powder；
(2) smashed peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are mixed, water is added and is cooked by slow fire
60min is filtered to remove the solid dregs of a decoction after decoction；
(3) heating concentration will be carried out in the liquid medicine after decoction, being concentrated into liquor strength is 3.0%；
(4) it will be proportionally added into honey, probiotics, Yunnan Baiyao and Radix zanthoxyli ethanol extract in the medical fluid of concentration, mixes
It closes and Chinese medicine compound prescription mouthwash is uniformly made.
Embodiment 2
A kind of Chinese medicine compound prescription mouthwash, comprises the following components in parts by weight:
3 parts of Yunnan Baiyao, 15 parts of peppermint, 5 parts of honey, 3 parts of bifidobacterium lactis, 15 parts of Siraitia grosvenorii, 5 parts of Radix Glycyrrhizae, the leaf of bamboo 5
Part, 5 parts of Radix zanthoxyli ethanol extract, wherein Radix zanthoxyli ethanol extract includes the following steps preparation: choosing two sides crown block, clearly
It dries, crush after washing；Ethyl alcohol is added to be submerged, is evaporated under reduced pressure, collects 45 DEG C of fraction, as Radix zanthoxyli ethanol extract.
The preparation method of the Chinese medicine compound prescription mouthwash, comprising the following steps:
(1) peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are weighed in proportion, are broken into powder；
(2) smashed peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are mixed, water is added and is cooked by slow fire
100min is filtered to remove the solid dregs of a decoction after decoction；
(3) heating concentration will be carried out in the liquid medicine after decoction, being concentrated into liquor strength is 2.5%；
(4) it will be proportionally added into honey, probiotics, Yunnan Baiyao and Radix zanthoxyli ethanol extract in the medical fluid of concentration, mixes
It closes and Chinese medicine compound prescription mouthwash is uniformly made.
Embodiment 3
A kind of Chinese medicine compound prescription mouthwash, comprises the following components in parts by weight:
1 part of Yunnan Baiyao, 10 parts of peppermint, 5 parts of honey, 2 parts of bifidobacterium lactis, 10 parts of Siraitia grosvenorii, 5 parts of Radix Glycyrrhizae, the leaf of bamboo 5
Part, 5 parts of Radix zanthoxyli ethanol extract, wherein Radix zanthoxyli ethanol extract includes the following steps preparation: choosing two sides crown block, clearly
It dries, crush after washing；Ethyl alcohol is added to be submerged, is evaporated under reduced pressure, collects 45 DEG C of fraction, as Radix zanthoxyli ethanol extract.
The preparation method of the Chinese medicine compound prescription mouthwash, comprising the following steps:
(1) peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are weighed in proportion, are broken into powder；
(2) smashed peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are mixed, water is added and is cooked by slow fire
120min is filtered to remove the solid dregs of a decoction after decoction；
(3) heating concentration will be carried out in the liquid medicine after decoction, being concentrated into liquor strength is 1.5%；
(4) it will be proportionally added into honey, probiotics, Yunnan Baiyao and Radix zanthoxyli ethanol extract in the medical fluid of concentration, mixes
It closes and Chinese medicine compound prescription mouthwash is uniformly made.
Crowd by Chinese medicine compound prescription mouthwash prepared by 1-3 of the embodiment of the present invention to the age at 35-60 years old carries out using often
Day p.prand uses, and service life is 1 month, and the periodontal disease of tester is obviously improved after the test, and is examined
It surveys flora in oral cavity and does not find detuning phenomena.
Used herein a specific example illustrates the principle and implementation of the invention, and above embodiments are said
It is bright to be merely used to help understand method and its core concept of the invention；At the same time, for those skilled in the art, foundation
Thought of the invention, there will be changes in the specific implementation manner and application range.In conclusion the content of the present specification is not
It is interpreted as limitation of the present invention.
Claims (5)
1. a kind of Chinese medicine compound prescription mouthwash, which is characterized in that comprise the following components in parts by weight:
1-5 parts of Yunnan Baiyao,
10-20 parts of peppermint,
5-10 parts of honey,
2-5 parts of probiotics,
10-20 parts of Siraitia grosvenorii,
5-10 parts of Radix Glycyrrhizae,
5-10 parts of the leaf of bamboo.
2. Chinese medicine compound prescription mouthwash according to claim 1, which is characterized in that further include Radix zanthoxyli ethanol extract 5-10
Part.
3. Chinese medicine compound prescription mouthwash according to claim 2, which is characterized in that the Radix Zanthoxyli extract includes following step
Suddenly it is prepared:
Two sides crown block is chosen, dries, crush after cleaning；
Ethyl alcohol is added to be submerged, is evaporated under reduced pressure, collects 45-50 DEG C of fraction, as Radix zanthoxyli ethanol extract.
4. Chinese medicine compound prescription mouthwash according to claim 1, which is characterized in that the probiotics is lactobacillus fermenti, cream
At least one of its double discrimination bacillus.
5. the preparation method of Chinese medicine compound prescription mouthwash according to claim 1-4, which is characterized in that including following
Step:
(1) peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are weighed in proportion, are broken into powder；
(2) smashed peppermint, the leaf of bamboo, Siraitia grosvenorii and Radix Glycyrrhizae are mixed, water is added and carries out being cooked by slow fire 60-
120min is filtered to remove the solid dregs of a decoction after decoction；
(3) heating concentration will be carried out in the liquid medicine after decoction, being concentrated into liquor strength is 1.5%-3.5%；
(4) honey, probiotics, Yunnan Baiyao and Radix zanthoxyli ethanol extract will be proportionally added into the medical fluid of concentration, mixing is equal
It is even that Chinese medicine compound prescription mouthwash is made.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114869918A (en) * | 2022-05-16 | 2022-08-09 | 大连医科大学附属第一医院 | Medicine mixture for treating oral mucositis caused by chemotherapy and preparation method thereof |
| CN115844803A (en) * | 2022-11-21 | 2023-03-28 | 深圳小阔科技有限公司 | Composition for removing oral smoke smell and preparation method thereof |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1522687A (en) * | 2003-02-17 | 2004-08-25 | 北京泰瑞伟业科技有限公司 | Oral health product using adhesive material as carrier |
| CN101190239A (en) * | 2006-11-28 | 2008-06-04 | 景岳生物科技股份有限公司 | Products containing LP lactic acid bacteria |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114869918A (en) * | 2022-05-16 | 2022-08-09 | 大连医科大学附属第一医院 | Medicine mixture for treating oral mucositis caused by chemotherapy and preparation method thereof |
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Application publication date: 20190611 |