CN104825542A - Medical biological tooth desensitizer dressing and preparation method thereof - Google Patents
Medical biological tooth desensitizer dressing and preparation method thereof Download PDFInfo
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Abstract
The invention relates to medical biological dressing and concretely relates to medical biological tooth desensitizer dressing and a preparation method thereof. The medical biological dressing is prepared from wormwood extract, water-soluble chitosan, sorbitol, silica, radix scutellariae extract, selaginella tamariscina extract, licorice root extract, uronic acid, calcium hydrogen phosphate, water-soluble mint oil, vitamin C and vitamin E. Through compatibility of the above raw materials, a tooth regeneration organ is maximally retained and activated, an oral environment is improved, vitamins are supplied, cell renewing is promoted, oral pH balance is kept, oral tooth restoration is promoted, pain and discomfort caused by cold, hot, acid and sweet stimulation to enamel, dentin, gingiva and exposed tooth root are eliminated, and dental nerve sensitivity to cold, hot, acid and sweet is reduced. The medical biological tooth desensitizer dressing has good effects of treating and preventing dentine sensitivity, can treat oral diseases such as swelling and aching of gum, gum bleeding and periodontitis and has effects of diminishing inflammation, relieving pain and stopping bleeding.
Description
Technical field
The present invention relates to medical bio bressing technical field, be specifically related to a kind of medical bio tooth desensitizers dressing and preparation method thereof.
Background technology
Hemodia is ached, and is called dentin hypersensitiveness clinically, is that tooth is subject to environmental stimuli, as hot and cold, sour, sweet food thing stimulation and sting hard object, as the symptom of aching that little Semen Juglandis, Semen Pini etc. cause.Check on facing with probe, can find one or several sensitizing range, be characterized in that outbreak rapidly, pain is sharp-pointed, and the time is of short duration.Patient often when talking, blow to cold wind, or certain biting tooth when eating because of carelessness a bit causes pain, will alleviate a moment later.
Every meeting causes the integrity of dental surface enamel to be destroyed, thus the various odontopathies that dentin is exposed, as abrasion (often sting hard object, as little Semen Juglandis, meat bone etc., and sleep bruxism), the wound odontoclasis, for a long time improper neck portion wedge shaped defect, dental caries and the periodontal atrophy caused of brushing teeth that cause cause Root exposnre etc., all can cause dental hypersensitiveness.Dentin hypersensitiveness slowly can develop into pulpitis, periapical periodontitis etc., " has pulled out " it to finally may differing.
At present, the method for the treatment of dentin hypersensitiveness mainly contains laser desensitization, uses dentin adhesive desensitization, uses desensitizing toothpaste etc.Laser desensitizes.By irritated for the alignment probe of medical laser transmitter position, distance is several millimeter, through the irradiation of one or two minute, can reach desensitization object.This method instant effect (only need treatment once), cure rate is high, and curative effect is held time length, and not easily recurs, and is first-selected desensitization method.But because medical expense is higher, also do not popularize in China at present.Be applicable to sensitive tooth number few, and the irritated position clearly patient of limitation.Use dentin adhesive desensitizes.The dentin adhesive that this kind of material uses when being originally and repairing tooth defect, is only applicable to sensitive tooth number seldom, but irritated position patient more widely.The tooth of some patient of hypersensitivity is more, and irritated position is unclear, and allergic symptom is lighter.At this moment, desensitizing toothpaste has just become optimum selection.Desensitizing toothpaste is in the market a feast for the eyes, but does not have a desensitization effect good.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, provide that a kind of desensitization effect is good, the dressing of preparation method simple medical bio tooth desensitizers.
To achieve these goals, the present invention adopts following technical scheme: the dressing of a kind of medical bio tooth desensitizers, and the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10-25%
Sorbitol 10-25%
Chinese medicine extract 18-52%
Calcium hydrogen phosphate 1-6%
Alduronic acid 1-6%
Silica 1-5%
Vitamin C 0.5-2%
Vitamin E 0.1-1%
Water solublity Oleum menthae 1-3%
Carbomer 8-20%
Purified water surplus.
Wherein, described Chinese medicine extract is the mixture of wormwood extract, Radix Scutellariae extract, Herba Selaginellae extract and Radix Glycyrrhizae extract.
Preferably, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10-25%
Sorbitol 10-25%
Wormwood extract 10-20%
Radix Scutellariae extract 3-10%
Herba Selaginellae extract 2-10%
Radix Glycyrrhizae extract 3-12%
Calcium hydrogen phosphate 1-6%
Alduronic acid 1-6%
Silica 1-5%
Vitamin C 0.5-2%
Vitamin E 0.1-1%
Water solublity Oleum menthae 1-3%
Carbomer 8-20%
Purified water surplus.
Another is preferred, and the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10-20%
Sorbitol 15-25%
Wormwood extract 10-15%
Radix Scutellariae extract 5-10%
Herba Selaginellae extract 5-10%
Radix Glycyrrhizae extract 5-10%
Calcium hydrogen phosphate 1-5%
Alduronic acid 1-5%
Silica 1-5%
Vitamin C 1-2%
Vitamin E 0.5-1%
Water solublity Oleum menthae 1-2%
Carbomer 8-15%
Purified water surplus.
More preferred, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 20%
Sorbitol 12%
Wormwood extract 13%
Radix Scutellariae extract 3%
Herba Selaginellae extract 6%
Radix Glycyrrhizae extract 6%
Calcium hydrogen phosphate 5%
Alduronic acid 5%
Silicon dioxide 3%
Vitamin C 1%
Vitamin E 0.5%
Water solublity Oleum menthae 2%
Carbomer 15%
Purified water surplus.
Described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained after pulverizing.
A preparation method for medical bio tooth desensitizers dressing, it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
Water-soluble chitosan of the present invention has good biocompatibility, biological activity and biodegradable, and can be absorbed by the body utilization, has anti-inflammation, hemostasis, pain relieving, antiallergic, reduce wound surface ooze out and promote wound tissue's regeneration, reparation, healing, suppress and reduce the effect of cicatrization.The deacetylation of the water-soluble chitosan that the present invention adopts is more than or equal to 90%, and in deionized water, dissolubility is more than or equal to 98%.Water-soluble chitosan of the present invention has good biocompatibility, other raw material can be combined closely in dentinal tubule's wall, liquid flow in canaliculi dentales can be suppressed, the irritability of calm Intradental nerve, reduction Intradental nerve tip, this combination closely makes the present invention can treat dentine hypersensitivity for a long time, efficiently.
Sorbitol, as wetting agent, has moisture absorption, water retention, can prevent dressing cure hard of the present invention, and the usefulness such as make dressing of the present invention glossy.
Calcium hydrogen phosphate mainly plays the effect of buffer agent, reduces the concentration of hydroxide ion, controls the basicity of dressing.
Alduronic acid, i.e. hyaluronic acid (Hyaluronan, hyaluronic acid), also known as hyaluronic acid, coloured glaze sugar carbylic acid, its hyalomitome molecular energy carries the moisture of more than 500 times, better with the use of moistening effect with sorbitol.
Radix Glycyrrhizae sweet in the mouth in Radix Glycyrrhizae extract is sweet, and property is gentle, enters the heart, spleen, lung, stomach four warp, has the effect of antiinflammatory antiallergic.
Herba Selaginellae in Herba Selaginellae extract has hemostasis, bacteriostasis.
Folium Artemisiae Argyi in wormwood extract has suppression and lethal effect to much virus and antibacterial, and modern experimental research proves, Folium Artemisiae Argyi has antibacterial and antivirus action; Relieving asthma, antitussive and phlegm-dispelling functions; Hemostasis and blood coagulation resisting function; Calmness and anti-allergic effects; Hepatoprotective choleretic effect etc.
Nature and flavor bitter cold in Radix Scutellariae extract, tool removing the relative excess fire, except damp and hot, hemostasis, antiabortive effect.Prove according to modern pharmacological research, baicalin contained by scutellariae,radix, baicalin former (baicalin) can destroy the enzyme activition system (SH enzyme) of mastocyte, suppress the release of allergic mediators, and the permeability of blood capillary can be reduced, have antihistamine and anti-acetylcholine effect, thus Radix Scutellariae effectively can prevent, control scytitis.In addition, Radix Scutellariae has wider antibacterial activity, also has inhibitory action to a certain degree to dermatophytes.
Water solublity Oleum menthae is the indispensable composition of one giving dressing cooling feeling, and it not only can make dressing have fragrance, eliminates tooth abnormal flavour, and its penetrating power is very strong, has very strong biocidal efficacies.
Vitamin C is that antibody and collagen are formed, tissue repairing's (comprising some redox), the metabolism of phenylalanine, tyrosine, folic acid, the utilization of ferrum, carbohydrate, the synthesis of fat, protein, maintains immunologic function, hydroxylation and hydroxytryptamine, keep the complete of blood vessel, promote that the institutes such as nonheme iron absorption are required
Vitamin E enters Skin Cell and more can directly help skin to resist the infringement of pollutant, the healing of accelerated in wounds.
Compared with prior art, beneficial effect is in the present invention:
(1) medical bio tooth desensitizers dressing of the present invention adopts wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, alduronic acid, water solublity Oleum menthae, vitamin C, the raw materials such as vitamin E, these raw materials cooperatively interact, learn from other's strong points to offset one's weaknesses, retain to greatest extent and activate regeneration of tooth organ, improve oral environment, vitimin supplement, promote cell turnover, maintain the balance of ph value of oral cavity, thus promote the reparation of Buccodental, can eliminate because of cold, heat, acid, sweet in enamel, dentin, gingiva and expose the stimulation of root of the tooth and the misery that causes and all discomforts, reduce dental nerve to cold and hot sour-sweet sensitivity, good treatment and preventive effect is had to dentin hypersensitiveness, gingival swelling and pain can be eliminated, hemorrhage, the oral diseases such as periodontitis, there is antiinflammatory, pain relieving, the effect of hemostasis.
(2) biocompatibility of medical bio tooth desensitizers of the present invention dressing meets GB/T 16886.11-2011 requirement.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
embodiment 1.
The dressing of a kind of medical bio tooth desensitizers, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10%
Sorbitol 25%
Wormwood extract 10%
Radix Scutellariae extract 10%
Herba Selaginellae extract 2%
Radix Glycyrrhizae extract 12%
Calcium hydrogen phosphate 1%
Alduronic acid 6%
Silica 1 %
Vitamin C 2%
Vitamin E 0.1%
Water solublity Oleum menthae 3%
Carbomer 8%
Purified water surplus.
Described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained after pulverizing.
A preparation method for medical bio tooth desensitizers dressing, it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
embodiment 2.
The dressing of a kind of medical bio tooth desensitizers, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 25%
Sorbitol 10%
Wormwood extract 20%
Radix Scutellariae extract 3%
Herba Selaginellae extract 10%
Radix Glycyrrhizae extract 3%
Calcium hydrogen phosphate 6%
Alduronic acid 1%
Silicon dioxide 5%
Vitamin C 0.5%
Vitamin E 1%
Water solublity Oleum menthae 1%
Carbomer 20%
Purified water surplus.
Described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained after pulverizing.
A preparation method for medical bio tooth desensitizers dressing, it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
embodiment 3.
The dressing of a kind of medical bio tooth desensitizers, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 18%
Sorbitol 22%
Wormwood extract 17%
Radix Scutellariae extract 8%
Herba Selaginellae extract 7%
Radix Glycyrrhizae extract 9%
Calcium hydrogen phosphate 4%
Alduronic acid 5%
Silicon dioxide 3%
Vitamin C 1%
Vitamin E 1%
Water solublity Oleum menthae 2%
Carbomer 15%
Purified water surplus.
Described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained after pulverizing.
A preparation method for medical bio tooth desensitizers dressing, it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
embodiment 4.
The dressing of a kind of medical bio tooth desensitizers, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 21%
Sorbitol 19%
Wormwood extract 17%
Radix Scutellariae extract 5%
Herba Selaginellae extract 8%
Radix Glycyrrhizae extract 11%
Calcium hydrogen phosphate 2%
Alduronic acid 4%
Silicon dioxide 3%
Vitamin C 1%
Vitamin E 0.5%
Water solublity Oleum menthae 2%
Carbomer 13%
Purified water surplus.
Described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained after pulverizing.
A preparation method for medical bio tooth desensitizers dressing, it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract thing, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
embodiment 5.
The dressing of a kind of medical bio tooth desensitizers, the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 20%
Sorbitol 12%
Wormwood extract 13%
Radix Scutellariae extract 3%
Herba Selaginellae extract 6%
Radix Glycyrrhizae extract 6%
Calcium hydrogen phosphate 5%
Alduronic acid 5%
Silicon dioxide 3%
Vitamin C 1%
Vitamin E 0.5%
Water solublity Oleum menthae 2%
Carbomer 15%
Purified water surplus.
Described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing.
Described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained after pulverizing.
A preparation method for medical bio tooth desensitizers dressing, it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
minute analgesia desensitization test:100 person-times of odonthemodia patients brush teeth, and freeze water carry out irritant test after 1 minute with frozen water and acid, result effective number 22 people, and efficiently individual quantity more than 82,2 people are without obvious sensation.
Experimenter adheres to using medical bio tooth desensitizers of the present invention dressing every day, each 1 time sooner or later, each 3-5 minute, and after 30 days, experimenter obviously feels that sensitivity of tooth degree reduces, and tooth is ached alleviation, all has desensitization effect.
Mrs Fang, female, 58 years old, suffer from the oral diseases such as toothache, dentin hypersensitiveness for many years, adopted acupuncture, cup and took tablet for alleviating pain etc., and being also stomatological hospital and having treated, but have little effect, normal recurrent exerbation, can not take food time serious, and rear clothes adheres to using medical bio tooth desensitizers of the present invention dressing every day, every day is sooner or later after meal containing dressing 3-5min of the present invention, namely toothache in second day and allergic symptom alleviate, harder food of can taking food after four days, and sensation of pricking disappears.
Mr. Zhao, man, 53 years old, suffer from dental hypersensitivity, particularly to cold allergy, after edible frozen foods, cause tooth to have pain as bony spur, every day sooner or later after meal containing dressing 3-5min of the present invention, two days afterwards toothache and allergic symptom namely alleviate, after six days, sensation of pricking disappears completely.
Ms Zhang, female, 64 years old, odontoseisis, gingival sensitivity tingle, harder food of can not taking food, makes patient suffering can't bear, and every day is sooner or later after meal containing dressing 3-5min of the present invention, two days afterwards toothache and allergic symptom namely alleviate, harder food of can taking food after seven days, sensation of pricking disappear.
Mr. Cai, man, 36 years old, hemodia is caused because suffering from dental caries, normally can not take food, particularly eat of vinegar-pepper food, twinge unbearably, very large misery is caused to him, every day, after three days, namely allergic symptom alleviated, some vinegar-pepper foods of can taking food after seven days sooner or later after meal containing dressing 3-5min of the present invention, sensation of pricking alleviates greatly, and after ten days, sensation of pricking disappears substantially.
Finally should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention; but not limiting the scope of the invention; although done to explain to the present invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify to technical scheme of the present invention or equivalent replacement, and not depart from essence and the scope of technical solution of the present invention.
Claims (10)
1. a medical bio tooth desensitizers dressing, is characterized in that: the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10-25%
Sorbitol 10-25%
Chinese medicine extract 18-52%
Calcium hydrogen phosphate 1-6%
Alduronic acid 1-6%
Silica 1-5%
Vitamin C 0.5-2%
Vitamin E 0.1-1%
Water solublity Oleum menthae 1-3%
Carbomer 8-20%
Purified water surplus.
2. a kind of medical bio tooth desensitizers according to claim 1 dressing, is characterized in that: described Chinese medicine extract is the mixture of wormwood extract, Radix Scutellariae extract, Herba Selaginellae extract and Radix Glycyrrhizae extract.
3. a kind of medical bio tooth desensitizers according to claim 1 and 2 dressing, is characterized in that: the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10-25%
Sorbitol 10-25%
Wormwood extract 10-20%
Radix Scutellariae extract 3-10%
Herba Selaginellae extract 2-10%
Radix Glycyrrhizae extract 3-12%
Calcium hydrogen phosphate 1-6%
Alduronic acid 1-6%
Silica 1-5%
Vitamin C 0.5-2%
Vitamin E 0.1-1%
Water solublity Oleum menthae 1-3%
Carbomer 8-20%
Purified water surplus.
4. a kind of medical bio tooth desensitizers according to claim 1 dressing, is characterized in that: the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 10-20%
Sorbitol 15-25%
Wormwood extract 10-15%
Radix Scutellariae extract 5-10%
Herba Selaginellae extract 5-10%
Radix Glycyrrhizae extract 5-10%
Calcium hydrogen phosphate 1-5%
Alduronic acid 1-5%
Silica 1-5%
Vitamin C 1-2%
Vitamin E 0.5-1%
Water solublity Oleum menthae 1-2%
Carbomer 8-15%
Purified water surplus.
5. a kind of medical bio tooth desensitizers according to claim 1 dressing, is characterized in that: the dressing of described medical bio tooth desensitizers is made up of the raw material of following percentage by weight:
Water-soluble chitosan 20%
Sorbitol 12%
Wormwood extract 13%
Radix Scutellariae extract 3%
Herba Selaginellae extract 6%
Radix Glycyrrhizae extract 6%
Calcium hydrogen phosphate 5%
Alduronic acid 5%
Silicon dioxide 3%
Vitamin C 1%
Vitamin E 0.5%
Water solublity Oleum menthae 2%
Carbomer 15%
Purified water surplus.
6. a kind of medical bio tooth desensitizers according to claim 2 dressing, is characterized in that: described wormwood extract is that Folium Artemisiae Argyi filters with 100 eye mesh screens the powder obtained after pulverizing.
7. a kind of medical bio tooth desensitizers according to claim 2 dressing, is characterized in that: described Radix Scutellariae extract is that Radix Scutellariae filters with 100 eye mesh screens the powder obtained through pulverizing.
8. a kind of medical bio tooth desensitizers according to claim 2 dressing, is characterized in that: described Herba Selaginellae extract is that Herba Selaginellae filters with 100 eye mesh screens the powder obtained after pulverizing and filtering with 100 eye mesh screens.
9. a kind of medical bio tooth desensitizers according to claim 2 dressing, is characterized in that: described Radix Glycyrrhizae extract is that Radix Glycyrrhizae filters with 100 eye mesh screens the powder obtained through pulverizing.
10. the preparation method of a kind of medical bio tooth desensitizers dressing described in any one of claim 2-9, is characterized in that: it comprises following preparation process:
Steps A, take each raw material by weight percentage, for subsequent use;
Step B, carbomer is added purified water, make it fully swelling, obtain the swelling body of carbomer, for subsequent use;
Step C, wormwood extract, water-soluble chitosan, sorbitol, Radix Scutellariae extract, Herba Selaginellae extract, Radix Glycyrrhizae extract, calcium hydrogen phosphate, alduronic acid, silicon dioxide, water solublity Oleum menthae, vitamin C, vitamin E are added in purified water, stir, obtain mixed liquor;
Step D, swelling for carbomer body is joined in mixed liquor, add purified water adjusting viscosity, stir, sterilizing, obtain the dressing of a kind of medical bio tooth desensitizers.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106344450A (en) * | 2016-09-14 | 2017-01-25 | 杭州惠博士生物科技有限公司 | Hyaluronic-acid tooth-brushing tablets and preparation method thereof |
| WO2017086998A1 (en) * | 2015-11-20 | 2017-05-26 | Colgate-Palmolive Company | Oral care composition comprising chitosan and silica |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017086998A1 (en) * | 2015-11-20 | 2017-05-26 | Colgate-Palmolive Company | Oral care composition comprising chitosan and silica |
| CN108289802A (en) * | 2015-11-20 | 2018-07-17 | 高露洁-棕榄公司 | Include the oral care composition of chitosan and silica |
| AU2015414791B2 (en) * | 2015-11-20 | 2019-02-21 | Colgate-Palmolive Company | Oral care composition comprising chitosan and silica |
| AU2019203372B2 (en) * | 2015-11-20 | 2020-08-13 | Colgate-Palmolive Company | Oral care composition comprising chitosan and silica |
| CN106344450A (en) * | 2016-09-14 | 2017-01-25 | 杭州惠博士生物科技有限公司 | Hyaluronic-acid tooth-brushing tablets and preparation method thereof |
| CN113648227A (en) * | 2021-08-24 | 2021-11-16 | 浙江大学 | Dental adhesion pretreatment agent based on cationic polymer-metal complex and use method thereof |
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