KR20180098048A - Mouthwash containing green tea - Google Patents

Mouthwash containing green tea Download PDF

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Publication number
KR20180098048A
KR20180098048A KR1020170025030A KR20170025030A KR20180098048A KR 20180098048 A KR20180098048 A KR 20180098048A KR 1020170025030 A KR1020170025030 A KR 1020170025030A KR 20170025030 A KR20170025030 A KR 20170025030A KR 20180098048 A KR20180098048 A KR 20180098048A
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KR
South Korea
Prior art keywords
weight
parts
oral
green tea
mouthwash
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Application number
KR1020170025030A
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Korean (ko)
Inventor
장 젱
Original Assignee
광저우 바이윈 시징 싱첸 엘티디
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Priority to KR1020170025030A priority Critical patent/KR20180098048A/en
Publication of KR20180098048A publication Critical patent/KR20180098048A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof

Abstract

Disclosed in the present invention is a mouthwash comprising: 20-30 parts by weight of Fineleaf Schizonepeta herb; 20-30 parts by weight of Capillary Wormwood herb; 6-8 parts by weight of Rhizoma alismatis; 20-40 parts by weight of green tea; 20-40 parts by weight of watermelon peel; and 20-40 parts by weight of Radix ophiopogonis. A production method for the mouthwash comprises the steps of: mixing and pulverizing the above ingredients to produce a paste to use; adding 200-400 parts by weight of pure water to the paste, and slowly heating and boiling the mixture for 40-60 minutes; and after boiling, filtering the mixture to produce a supernatant as a finished mouthwash product. The mouthwash of the present invention overcomes the shortcomings in health management functionalities of conventional mouthwashes; has good comprehensive pharmacological effects; can prevent diseases of oral cavity; and can provide beneficial effects for teeth.

Description

MOUTHWASH CONTAINING GREEN TEA}

The present invention relates to mouthwashes containing green tea.

Conventional oral cleansers have a high or low concentration, whereas oral cleansers with high concentrations are used after dilution with water, and oral cleansers having low concentrations can be used directly. The conventional oral cleansers are typically classified as follows:

1. Fluoride-containing mouthwash

Fluoride-containing mouthwashes contain mostly 0.05% sodium fluoride and can supply additional fluoride to those in need. While the fluoride containing oral cleansers may help eliminate dental plaque, excessive intake of fluorine containing compounds pose a health hazard.

2. Oral cleanser to prevent dental plaque biofilm

These oral cleaners help to reduce the likelihood of gum inflammation by preventing accumulation of gingival biofilm. This includes mainly triclosan, thymol, hexadecyl chloride and the like. However, many facts indicate that these oral cleansers can not prevent periodontal disease.

3. Oral cleanser that can inhibit dental biofilm

Chlorohexidine gluconate has been shown to effectively inhibit the growth of dental biofilm and prevent periodontal disease. However, this, when used for a long time, easily deposits tooth stains on the tooth surface, affects the taste and causes recurrent aphtha.

4. Anti-allergic mouthwash

The major chemical components of these mouthwashes, such as potassium nitrate, can reduce tooth allergy by allowing the microtubules of the dentin to be sealed. However, antiallergic mouthwashes should not be used for a long period of time.

5. Herbal mouthwash

Herbal mouthwashes are mostly extracted from tea leaves, are rich in vitamins, have sterilization and cavitation inhibiting effects, and have high oxidation resistance. The catechins contained therein can penetrate into tooth slits and cavities and effectively inhibit bacteria to protect oral health.

6. Traditional Chinese herbal medicine mouthwash

These oral cleansers are those that are purified from purely medicinal materials that are pharmaceutically usable and eatable. It mainly contains agastache, elsholtzia, clove, etc. and does not contain widely sterilized chemical components such as alcohol, antibiotics, and triclosan. It is characterized by traditional Chinese medical culture and can be used for young, old and pregnant women.

Regular green tea is 99.9% water, 1 calorie per 100 mL, no significant nutrients (food), and contains plant chemicals such as polyphenols and caffeine. The polyphenols present in green tea include epigallocatechin gallate (EGCG), epicatechin gallate, epicatechin and flavonol.

Although many claims have been made about the health benefits of green tea, clinical studies on humans have shown no conclusive evidence of random effects. In 2011, a panel of scientists issued a report on the claims of health effects at the request of the European Commission, which generally confirmed that the claims made against green tea were not supported by sufficient scientific evidence.

The average content of flavonoids and catechins contained in one cup of green tea was higher than the average content in other foods and beverages of the same volume that were traditionally thought to promote health, but flavonoids and catechins did not demonstrate biological effects in humans.

The present invention is intended to overcome the drawbacks of the health care performance of the conventional oral cleanser and is an oral cleansing agent characterized by using green tea as a main raw material and combining the effects of traditional Chinese medicines and research results of modern pharmacy, The present invention provides an oral cleanser having good pharmaceutical properties, preventing oral diseases, and having a beneficial effect on teeth.

Accordingly, the present invention provides a pharmaceutical composition comprising 20 to 30 parts by weight of a mold (Fineleaf Schizonepeta Herb), 20 to 30 parts by weight of Capillary Wormwood Herb, 6 to 8 parts by weight of Rhizoma alismatis, 20 to 40 parts by weight of green tea, 20 To 40 parts by weight of Watermelon peel and 20 to 40 parts by weight of Radix ophiopogonis,

Mixing and pulverizing the raw materials to obtain a paste to be used;

200 to 400 parts by weight of pure water is added to the paste, and the mixture is heated gently for 40 to 60 minutes;

Followed by filtration to obtain the supernatant as an oral cleaning agent.

For use, the oral cleanser is diluted with 10 to 20 times of clear water, then filled into the mouth, both the balls and lips are moved, the clear water is sufficiently brought into contact with the teeth and the gums, Wash each part repeatedly.

Green tea is one of the main tea in China. It is a drink made by picking young leaves and shoots of green tea (not fermented), fixing, reshaping and drying.

Other features and advantages of the present invention will be described in detail in the section of the following specific embodiments.

The present invention is an oral cleansing agent characterized by using green tea as a main raw material to overcome the disadvantages of the health care performance of the conventional oral cleanser and combining the effects of traditional Chinese medicines and research results of modern pharmacy, Is good, can prevent oral disease, has a beneficial effect on teeth.

Without loss of generality, the present invention provides a composition comprising 20 to 30 parts by weight of Fineleaf Schizonepeta Herb, 20 to 30 parts by weight of Capillary Wormwood Herb, 6 to 8 parts by weight of Rhizoma alismatis, 20 to 40 parts by weight of Green tea, 20 to 40 parts by weight of Watermelon peel, and 20 to 40 parts by weight of Radix ophiopogonis,

Mixing and pulverizing the raw materials to obtain a paste to be used;

200 to 400 parts by weight of pure water is added to the paste, and the mixture is heated gently for 40 to 60 minutes;

Followed by filtration to obtain the supernatant as a mouthwash finished product.

The oral cleanser provided in the present invention has the effect of inhibiting allergy, treating periodontitis, treating oral ulcers, removing bad breath, removing plaque, controlling bad breath, and cleansing mouth.

For use, the oral cleanser needs to be diluted with 10 to 20 times clear water, then filled into the mouth, the transparent balls are brought into contact with the teeth and gums sufficiently while moving both the balls and the lips, And repeatedly washing each part of the oral cavity.

The following examples further illustrate the present invention.

Example  1 to 5

Examples 1 to 5 are used to illustrate the oral cleanser provided by the present invention.

Preferably, the filtration membranes for filtration in Examples 1 to 5 have a pore diameter of 0.45 mm.

According to the above ratios, oral cleaners 1 to 5 containing green tea in Examples 1 to 5 were obtained and are shown in Table 1 below.

Figure pat00001

Experimental Example  1 to 5

Experimental Examples 1 to 5 are used to illustrate the dental health care and protective effects of the oral cleanser provided by the present invention.

(1) relief of oral mucosa allergy

150 male and female subjects (age range 25 to 40 years) with different degrees of oral mucosal allergy symptoms were selected and randomly divided into 5 groups of 30 patients per group. The oral hygiene agent of the present invention was used for five weeks each, and the effect was observed. When compared with the state before use of the oral hygiene agent, subjects who completely disappeared allergic symptoms were recorded as O, Subjects were recorded as Δ, subjects who did not significantly alleviate allergic symptoms were recorded as X, and their health care effects are shown in Table 2 below.

Figure pat00002

From the experimental results of the above Experimental Example, the present invention fully utilizes the health care effect of green tea to maintain normal function of oral mucosa and combines with traditional herbal medicine components of capillary wormwood herb and watermelon skin to exhibit comprehensive pharmacological effects . As a result of dedication to research, the present inventors have found that green tea can produce a chemical substance capable of promoting deallergization of oral mucosa, and the chemical substance is capable of releasing water and nutrients to the outer surface of the oral mucosa through the oral mucosa Absorption can be promoted and cell viability can be enhanced to further attain the technical effects of helping the oral mucosa to become de-allergic and inhibiting allergy. The actual field test results show that after the oral care agent of the present invention is used for one week, the allergic symptoms of the oral mucosa can be effectively alleviated or disappear, so that the antianaphylaxis of a patient having oral mucosal allergy, And satisfies the requirements to the maximum extent.

(2) relief of periodontitis

150 male and female patients (age range 20-35 years) with different degrees of periodontal symptoms were selected and randomly divided into 5 groups of 30 patients per group. The oral cleaning agent of the present invention was used for five weeks each for 1 week and the effect was observed. Compared to the state before use of the oral cleansing agent, the patient who completely disappeared the symptoms of periodontal disease was recorded as O and markedly alleviated symptoms of periodontal disease Patients who did not significantly alleviate the symptoms of periodontal disease were recorded as X, and their health care effects are shown in Table 3 below.

Figure pat00003

From the experimental results of the above Experimental Example, the present invention fully utilizes the health care effect of green tea infestation and bacteriostasis, and achieves disinfection and anti-inflammatory effects by combining traditional herbal medicines such as molds and capillary wormwood herbs, , And further achieves a technical effect of alleviating and treating periodontitis.

(3) Mitigation of dental ulcers

150 male and female subjects (ages ranging from 20 to 40) were selected and randomly divided into 5 groups of 30 subjects per group. The oral cleaning agent of the present invention was used for 5 weeks each for 1 week and the effect was observed. When compared to the state before use of the oral cleanser, subjects who completely disappeared the symptoms of dental ulcer were recorded as O and the symptoms of dental ulcer Significantly relaxed subjects were rated as Δ, subjects who did not significantly alleviate dental ulcer symptoms were rated as X, and their healthcare effects are shown in Table 4 below.

Figure pat00004

From the experimental results of the above experimental examples, it can be seen that the present invention has excellent technical effects of treatment and alleviation for the treatment of dental ulcers. The present invention fully demonstrates the technical effects of the restoration factors caused by the mixing action of the mold, the capillary wormwood herb, the taxa and the green tea, and provides a strong technical basis for rapidly alleviating and treating dental ulcers. After the oral cleanser of the present invention is used by the subjects, the effect is further improved as compared to the prior art, and the treatment requirements for dental ulcer patients can be met to a maximum extent. Short-term application of the oral cleanser can achieve a technical effect that the ulcer wound is no longer painful, and ulcer wound dermal layer cells can be recovered after 3 to 4 days of application, and the wound can be fully healed within one week And the oral cleanser of the present invention is free from toxicity and side effects.

(4) Reduction of bad breath

150 male and female subjects with different degrees of bad breath (age range 20 to 40 years) were selected and randomly divided into 5 groups of 30 subjects per group. The oral cleanser of the present invention was used for five weeks each for one week and the effect was observed. Compared to the state before use of the oral cleanser, the subject who had completely lost the bad breath was recorded as O and the subject who had significantly lowered bad breath Was recorded as DELTA, and subjects who did not significantly alleviate halitosis were recorded as X, and their health care effects are shown in Table 5 below.

Figure pat00005

The present invention fully utilizes the technical effect due to green tea, effectively kills harmful bacteria which are easy to make odor in mouth, and provides effective technical basis for alleviating and eliminating odor. In addition, the addition of corn germs helps to destroy the odor-prone growth environment of the harmful bacteria, refreshes the mouth, and provides an additional technical basis for eliminating odors in the mouth. The above experimental results show that the present invention has a technical effect of effectively mitigating and eliminating bad breath.

(5) relieving plaque and tooth whitening

A selection of 150 male and female subjects (age range 20-45 years) with different degrees of plaque and yellow teeth were randomly divided into 5 groups of 30 subjects per group. The oral hygiene agent of the present invention was used for five weeks each for one week and the effect was observed. Compared to the state before use of the oral hygiene agent, subjects who completely disappeared were recorded with O, Subjects were recorded as Δ, subjects who did not significantly mitigate halitosis were recorded as X, and their health care effects are shown in Table 6 below.

Figure pat00006

As a result of the study, the present inventor has confirmed that there is also a technical effect of removing the tooth from the soup, which is a master from green tea. The present invention achieves the technical effect of fully exploiting the technical effects, suppressing the occurrence of plaque, effectively removing plaque, and promoting tooth whitening. Experimental results show that the plaque can be effectively removed after long-term application of the oral cleanser of the present invention, and the effect of plaque removal after a short-term application can be further improved as compared with the prior art.

Claims (5)

A green tea containing 20 to 30 parts by weight of a mold, 20 to 30 parts by weight of a capillary wormwood herb, 6 to 8 parts by weight of a taxane, 20 to 40 parts by weight of green tea, 20 to 40 parts by weight of a watermelon shell, As an oral cleanser,
Mixing and pulverizing the raw materials to obtain a paste to be used;
200 to 400 parts by weight of pure water is added to the paste, and the mixture is heated gently for 40 to 60 minutes;
Followed by filtration to obtain the supernatant as an oral cleaning agent.
The oral cleansing agent according to claim 1, comprising 25 parts by weight of mold, 25 parts by weight of capillary wormwood herb, 6 parts by weight of taxa, 20 parts by weight of green tea, 20 parts by weight of a watermelon shell, and 20 parts by weight of marshmallow. The oral cleansing agent according to claim 1, comprising 28 parts by weight of mold, 25 parts by weight of capillary wormwood herb, 7 parts by weight of taxa, 20 parts by weight of green tea, 30 parts by weight of a watermelon shell, and 30 parts by weight of marshmallow. The oral cleaning agent according to claim 1, comprising 28 parts by weight of moldings, 26 parts by weight of capillary waxy herb, 7 parts by weight of Tarsa, 30 parts by weight of green tea, 30 parts by weight of a watermelon shell, and 40 parts by weight of marshmallow. 5. The oral cleaning agent according to any one of claims 1 to 4, further comprising 0.5 to 1 part by weight of ethanol and 3 to 5 parts by weight of edible salt.




KR1020170025030A 2017-02-24 2017-02-24 Mouthwash containing green tea KR20180098048A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240005461A (en) 2022-07-05 2024-01-12 강원대학교산학협력단 Composition for mouthwash comprising SAEW and sodium benzoate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240005461A (en) 2022-07-05 2024-01-12 강원대학교산학협력단 Composition for mouthwash comprising SAEW and sodium benzoate

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