KR101902685B1 - Mouthwash containing green tea - Google Patents

Abstract

The present invention relates to a mouth rinse comprising 20 to 30 parts by weight of a pendant, 20 to 30 parts by weight of dermis, 6 to 8 parts by weight of glycerol, 20 to 40 parts by weight of green tea, 20 to 40 parts by weight of mold, . The method for producing the oral cleanser comprises the steps of: mixing and grinding raw materials to obtain a paste to be used; Adding 200 to 400 parts by weight of pure water to the paste, heating to mild for 40 to 60 minutes; And after filtration, filtration to obtain a supernatant as a mouthwash product. The oral cleanser provided in the present invention has the effect of resisting allergies, treating periodontal disease, treating oral ulcers, removing bad breath, eliminating calculus, inhibiting bad breath and cleaning oral cavity, Have a special effect for treating oral diseases.

Description

MOUTHWASH CONTAINING GREEN TEA}

The present invention relates to a green tea-containing mouthwash.

The oral cleanser in the prior art has a high or low concentration, wherein the oral cleanser having a high concentration is used after dilution with water, and the oral cleanser having a low concentration can be used immediately. Oral cleansers in the prior art are generally classified as follows:

1. Fluoride-Containing Oral Cleanser

Most fluoride-containing mouthwashes contain 0.05% sodium fluoride and can provide additional fluoride for those in need. Fluorine-containing mouthwashes may help to remove calculus, but excessive intake of fluorine-containing compounds causes health hazards.

2. Prevent dental plaque (biofilm) Oral cleanser

This oral cleanser helps prevent accumulation of dental plaque, thereby reducing the likelihood of gum inflammation. It mainly includes triclosan, thymol, hexadecyl chloride, and the like. However, more facts indicate that these oral cleansers can not prevent periodontal disease.

3. Oral cleansing agent that can inhibit dental plaque membrane:

Chlorhexidine gluconate has been shown to effectively inhibit the growth of dental plaque membranes and prevent periodontal disease. However, when used over a long period of time, tooth spots are easily deposited on the surface of the teeth, affecting the taste and causing recurrent aphtha.

4. Anti-allergy mouthwash

The main chemical component of this oral cleanser, such as potassium nitrate, can close the microtubules of the dentin, thereby reducing tooth allergy. However, anti-allergic mouthwashes should not be used for long periods.

5. Herbal Oral Cleanser

Herbal mouthwashes are mainly extracted from tea leaves and are rich in vitamins; It has a sterilization and anti-caries effect and a high resistance to oxidation. The catechins contained therein can penetrate into the tooth slit and tooth cavity, effectively inhibit bacteria, and protect the oral condition.

6. Traditional Chinese herbal medicine oral cleanser

These oral cleansers are purified from pharmaceutically acceptable and edible pure Chinese herbal medicines. It mainly contains agastache, elsholtzia, clove, etc., and does not contain wide-spectrum sterilizing chemical components such as alcohol, antibiotics, and triclosan. It has the characteristics of traditional Chinese medicinal culture and is available to children, the elderly and pregnant women.

Typical green tea is 99.9% water, provides one calorie per 100 mL provided, has no significant nutrient content (table), and contains phytochemicals such as polyphenols and caffeine. Polyphenols found in green tea contain epigallocatechin gallate (EGCG), epicatechin gallate, epicatechin and flavanol.

Numerous claims have been made for the health benefits of green tea, but human clinical trials have not provided conclusive evidence of some effects. In 2011, a panel of scientists issued a report on the claims of health effects at the request of the European Commission: Overall they found that claims to green tea were not supported by sufficient scientific evidence Respectively. The average content of flavonoids and catechins contained in a cup of green tea is higher than that of the same amount of other food and beverage items traditionally considered to promote health, [5] flavonoids and catechins have not been shown to have biological effects in humans .

SUMMARY OF THE INVENTION

The present invention provides an oral cleanser which is characterized by overcoming the shortage in the healthcare efficacy of the oral cleanser in the prior art, taking green tea as the main ingredient, and combining the effects of traditional medicinal materials with the research results of modern pharmacology Which has excellent overall pharmacological properties, can prevent oral diseases, and has beneficial effects on superior teeth.

For this reason, the present invention relates to a pharmaceutical composition comprising 20 to 30 parts by weight of Fructus forsythiae, 20 to 30 parts by weight of pericarpium citri reticulatae, 6 to 8 parts by weight of Rhizoma anemarrhenae, 20 to 40 parts by weight of green tea, 20 to 40 parts by weight of Schizonepeta, and 20 to 40 parts by weight of Wolfiporia extensa; The mouthwash is prepared by the following steps:

Mixing and grinding the raw materials to obtain a to-be-used paste;

Adding 200 to 400 parts by weight of pure water to the paste, heating to mild for 40 to 60 minutes; And

After filtration, filtrate to obtain a supernatant as a mouthwash product.

For use, the oral cleanser is diluted to an integer of 10 to 20 times, filled into the mouth, and is allowed to sufficiently contact the teeth and gums with the movement of both balls and lips, and repeatedly rinsed through hydraulic power.

Green tea: one of the main tea in China; Refers to beverages made by collecting (not fermenting), fixing, reshaping, and drying young leaves or shoots of tea trees.

Other features and advantages of the invention will be set forth in detail in the following sections of the specific embodiments.

Without loss of generality, the present invention provides a composition comprising 20 to 30 parts by weight of an alum, 20 to 30 parts by weight of dermis, 6 to 8 parts by weight of glycerol, 20 to 40 parts by weight of green tea, 20 to 40 parts by weight of mold, Discloses an oral cleanser comprising; The mouthwash is prepared by the following steps:

Mixing and grinding the raw materials to obtain a paste to be used;

Adding 200 to 400 parts by weight of pure water to the paste, heating to mild for 40 to 60 minutes; And

After filtration, filtrate to obtain a supernatant as an oral cleaning agent.

The oral cleanser provided in the present invention has an effect to resist allergy, to treat periodontitis, to treat oral ulcers, to remove bad breath, to remove calculus, to inhibit bad breath, and to clean oral cavity.

For use, the oral cleanser is only required to be diluted to an integer of 10 to 20 times, then filled into the mouth, with the motion of both balls and lips, allowing the cleansing to sufficiently contact the teeth and gums, The parts are washed repeatedly through the water.

The present invention is explained in more detail through the following examples.

Example  1-5:

Examples 1-5 were used to illustrate the mouthwash prepared by the present invention.

Preferably, in Example 1-5, the filter membrane for filtration has a pore diameter of 0.45 μm.

Based on the above ratios, the green tea-containing mouthwashes 1-5 of Example 1-5 were obtained and are shown in Table 1.

Example Abalone
(G) dermis
(G) Ji
(G) green tea
(G) Mold
(G) Boryeong
(G) ethanol
(G) Edible salt
(G) Example 1 200 200 60 200 200 200 0 0 Example 2 250 250 60 200 200 200 30 5 Example 3 280 250 70 200 300 300 40 8 Example 4 280 260 70 300 300 400 50 10 Example 5 300 300 80 400 400 400 0 0

Experimental Example  1-5

Experimental Examples 1-5 were used to illustrate tooth health care and protective effects of the oral cleanser provided by the present invention.

(1) relief of oral mucosa allergy

A selection of 150 male and female subjects (within the 25-40 age range) with different degrees of oral mucosal allergy were selected and each group was randomly divided into 5 groups, including 30 patients. The oral cleanser of the present invention was used in five groups each for one week and then the effect was observed where the experimenter who had completely lost the allergy symptoms compared to the state before use of the oral cleanser was marked with & This remarkably relaxed experimenter is marked with △, the experimenter without significant relief of allergy symptoms is marked with ×, and the healthcare effect is shown in Table 2.

group Effect (number of experimenter) ○ △ × One 19 8 3 2 20 6 4 3 23 5 2 4 22 7 One 5 21 4 5

As can be seen from the experimental results of the above Experimental Example, the present invention can sufficiently utilize the health care effect of green tea to maintain the normal function of the oral mucosa, and to combine the traditional Chinese medicinal components of the dermis and mold, . By focusing on the research, the inventors have found that green tea can produce chemicals that can promote deallergization of oral mucosa, and that the chemicals absorb water and nutrients on the outer surface of the oral mucosa by oral mucosa And further improves cell viability and further achieves a technical effect of helping the oral mucosa to become de-allergic and to resist allergy. Practical field tests have shown that allergic symptoms of the oral mucosa can be effectively relieved or disappeared after using the oral cleanser of the present invention for one week, thus maximizing the antianaphylaxis requirement of patients suffering from oral mucosal allergy .

(2) relief of periodontitis

150 male and female patients (within the age range of 20-35 years) with different degrees of periodontal disease were selected and each group was randomly divided into 5 groups, including 30 patients. The oral cleanser of the present invention was used in five groups each for one week and then the effect was observed wherein the experimenter who completely disappeared the symptoms of periodontal disease as compared to the state before use of the oral cleanser was marked as ○, Patients with this marked relief were marked as △, patients without significant relief of periodontitis symptoms were marked with ×, and healthcare effects were shown in Table 3.

group Effect (number of patients) ○ △ × One 18 10 2 2 19 8 3 3 22 6 2 4 20 8 2 5 17 8 5

As can be seen from the experimental results of the above experimental examples, the present invention fully utilizes the healthcare effect of antiphlogosis and bacteriostasis of green tea, The combination achieves the effect of disinfection and anti-inflammation, further effectively achieves the technical effect of relieving symptoms of swelling and tingling of the gums and gingival congestion, and alleviating and treating periodontitis.

(3) relief of dental ulcers

150 male and female subjects (within the age range of 20-40 years) were selected, and each group was randomly divided into 5 groups, including 30 subjects. The oral cleanser of the present invention was used in five groups each for one week, and then the effect was observed. Here, the experimenter who completely disappeared the symptoms of dental ulcers compared to the state before use of the oral cleanser was marked as " Experiments with significantly reduced ulcer symptoms were marked with △, those without significant relief of dental ulcer symptoms were marked with ×, and healthcare effects were shown in Table 4.

group Effect (number of experimenter) ○ △ × One 16 10 4 2 19 8 3 3 25 4 One 4 22 4 4 5 19 10 One

As can be seen from the experimental results of the above Experimental Example, the present invention has excellent technical effects on treatment and alleviation of dental ulcer treatment. The present invention fully demonstrates the technical effects of the restorative factors produced by the combined action of ligament, dermis, dermis and green tea and provides strong technical support for the rapid relief and treatment of dental ulcers. After using the oral cleanser in the present invention by the experimenter, the effects were further improved as compared to the prior art and the treatment requirements for dental ulcer patients could be satisfied to a maximum extent. Short-term application of mouthwash can achieve the technical effect that the ulcer wounds no longer cause pain, ulcer wound dermal cells can be recovered after 3-4 days of application, wounds can be completely cured within one week , The mouthwash according to the present invention does not have toxicity and side effects.

(4) alleviation of bad breath

150 male and female subjects with different degrees of bad breath (within the age range of 20-40 years) were selected and each group was randomly divided into 5 groups, including 30 subjects. The oral cleanser of the present invention was used in five groups each for one week and then the effect was observed where the odor eliminator completely disappeared compared to the condition before the oral cleanser was used, This significantly relaxed experimenter was marked with △, the experimenter without significant relief of bad breath was marked with ×, and the healthcare effect is shown in Table 5.

group Effect (number of experimenter) ○ △ × One 16 10 4 2 18 8 4 3 22 6 2 4 20 9 One 5 19 6 5

The present invention fully utilizes the technical effects resulting from green tea, effectively kills harmful bacteria that tend to create odors in the mouth, and provides effective technical support to alleviate and eliminate bad breath. In addition, the addition of bamboo helps to break the growth environment of harmful bacteria which tends to refresh the mouth, create odors, and provides additional technical support to eliminate odors in the mouth. These experiments show that the present invention has the technical effect of effectively alleviating and eliminating bad breath.

(5) Elimination of tartar and reduction of tooth whitening

A selection of 150 male and female subjects (within the age range 20-45 years) with different degrees of calculus and yellow teeth were selected and each group was randomly divided into 5 groups, including 30 subjects. The oral cleanser of the present invention was used in five groups each for one week and then the effect was observed wherein the experimenter effectively removed the tartar as compared to the condition prior to use of the oral cleanser was marked with & Experiments that were removed to some extent were marked with △, those without significant plaque mitigation were marked with ×, and healthcare effects are shown in Table 6.

group Effect (number of experimenter) ○ △ × One 18 9 3 2 19 8 3 3 24 5 One 4 21 8 One 5 17 9 4

Focusing on the study, the present inventors have found that green tea soup also has a technical effect of removing calculus. INDUSTRIAL APPLICABILITY The present invention fully utilizes the technical effects described above to achieve a technical effect of suppressing the generation of tartar, effectively removing tartar, and promoting tooth whitening. These experiments can effectively remove tartar after long-term application of the oral cleanser of the present invention; After a short period of application, the effect of tartar removal can be further improved compared to the prior art.

Claims (5)

25 parts by weight of bridges, 25 parts by weight of dermis, 6 parts by weight of glycerol, 20 parts by weight of green tea, 20 parts by weight of moldings and 20 parts by weight of gum;
28 parts by weight of bridged, 25 parts by weight of dermis, 7 parts by weight of glycerol, 20 parts by weight of green tea, 30 parts by weight of moldings and 30 parts by weight of gum; or
A mouthwash containing green tea, comprising 28 parts by weight of alum, 26 parts by weight of dermis, 7 parts by weight of glycerol, 30 parts by weight of green tea, 30 parts by weight of mold, and 40 parts by weight of bamboo, the mouthwash comprising The mouthwash, which is manufactured by:
Mixing and grinding the raw materials to obtain a paste;
Adding 200 to 400 parts by weight of pure water to the paste, heating to mild for 40 to 60 minutes; And
After filtration, filtrate to obtain a supernatant as a mouthwash product. The mouthwash according to claim 1, further comprising 0.5 to 1 part by weight of ethanol and 3 to 5 parts by weight of edible salt. delete delete delete