CH714586A2 - Green tea-containing mouthwash. - Google Patents

Abstract

The present invention discloses a mouthwash comprising by weight parts: Flos Sophorae 20-30, Agastache rugosa 20-30, Plantane Herb 6-8, Green Tea 20-40, Long Haired Antenoron Herb 20-40 and Pomegranate Peel 20-40. The mouthwash manufacturing process comprises the following steps: mixing and milling the raw materials to obtain a paste to be used; Add 200-400 parts by weight of pure water to the paste and gently heat to boil over 40-60 minutes; and filtering after decoction to obtain a supernatant as a finished mouthwash product.

Description

description

TECHNICAL FIELD The invention relates to a mouthwash containing green tea.

BACKGROUND The prior art mouthwashes have a high or low concentration where the high concentration mouthwash is used after dilution with water and the low concentration mouthwash can be used immediately. The prior art mouthwashes are typically classified as follows:

1. Fluorine-containing mouthwash Most fluoride-containing mouthwashes contain 0.05% sodium fluoride and can provide additional fluoride to people who are undersupplied. Even if the fluorine-containing mouthwash can help to remove dental plaque, an excessive intake of fluorine-containing compounds leads to a health hazard.

2. Mouthwash to Prevent Dental Plaque Biofilm This mouthwash helps prevent dental plaque biofilm from building up, thereby reducing the possibility of gingivitis. It mainly contains triclosan, thymol, hexadecyl chloride, etc. However, more facts indicate that this mouthwash cannot prevent periodontal disease.

3. Mouthwash that can inhibit dental plaque biofilm. It has been confirmed that chlorhexidine gluconate can effectively inhibit dental plaque biofilm formation and prevent periodontal disease. With long-term use, however, it quickly leads to the formation of tooth stains on the tooth surface, affects the taste and leads to recurring aphthae.

4. Anti-allergy mouthwash The main chemical component of this mouthwash, such as potassium nitrate, can allow the dentin microtubules to close, thereby reducing dental allergy. Anti-allergy mouthwash should not be used in the long term.

5. Herbal Mouthwash Herbal mouthwash is predominantly obtained from tea leaves and is rich in vitamins; it has sterilizing and caries-fighting effects as well as a high resistance to oxidation. The catechin contained in it can penetrate the tooth space and cavity, effectively inhibit bacteria, in order to maintain oral health.

6. Traditional Chinese Herbal Medicine Mouthwash Such a mouthwash is further developed from pure Chinese herbal medicine that is pharmaceutically available and edible. It mainly includes Agastache, Elsholtzia, clove etc. and does not contain any chemical broad-spectrum disinfectants such as alcohol, antibiotics, triclosan. It has a characteristic of the culture of traditional Chinese medicine and is available for young and old as well as pregnant women.

Normal green tea consists of 99.9% water, provides 1 calorie per serving to 100 ml, is free of significant nutrient content (table) and contains phytochemicals, such as polyphenols and caffeine. Polyphenols found in green tea include epigallocatechin gallate (EGCG), epicatechin gallate and flavanols.

[0010] Although numerous claims have been made regarding the health benefits of green tea, human clinical research has not provided conclusive evidence of any effects. In 2011, a group of scientists published a report on behalf of the European Commission on the alleged health effects: in general, it was found that the claims made about green tea are not supported by sufficient scientific evidence. Even if the mean content of flavonoids and catechins in a cup of green tea is higher than in the same volume of other foods and beverages that are traditionally considered to be health-promoting, [5] flavonoids and catechins have no proven biological effect in humans.

SUMMARY OF THE INVENTION The present invention seeks to remedy the deficiencies in the health benefits of the prior art mouthwash and provides an mouthwash which is characterized by using green tea as a primary raw material and combining the effects of traditional ones Drugs and the research track

CH 714 586 A2 of modern pharmacology, which has a good comprehensive pharmaceutical property, can prevent oral disease and has a good tooth-promoting effect.

For this reason, the present invention provides a mouthwash which includes parts by weight: Flos Sophorae 20-30, Agastache rugosa 20-30, plantane herb 6-8, green tea 20-40, long-haired Antenoron herb 20-40 and pomegranate peel 20-40; the mouthwash being made by the steps of: mixing and grinding the raw materials to obtain a paste to be used;

Add 200-400 parts by weight of pure water to the paste and gentle heating for boiling over 40-60 min;

and after boiling, filter to obtain a supernatant as a finished mouthwash product.

For use, the above mouthwash is diluted with 10-20 times clear water and is then placed in the mouth, with movement of the two cheeks and the lip, a sufficient wetting of the teeth and gums with the clear water enables and every part of the oral cavity is washed repeatedly thanks to hydropower.

Green tea: is one of the most important teas in China; means a drink that is made by picking young leaves or buds of the tea tree (without fermentation), fixing, shaping and drying, etc.

In a following section of the specific embodiments, other features and advantages of the present invention are described in more detail.

DETAILED DESCRIPTION OF THE EMBODIMENTS Without limiting the generality, the present invention discloses a mouthwash which comprises parts by weight: Flos Sophorae 20-30, Agastache rugosa 20-30, plantane herb 6-8, green tea 20-40, long-haired Antenoron- Cabbage 20-40 and pomegranate peel 20-40; the mouthwash is made by the following steps:

Mixing and grinding the raw materials to obtain a paste to be used;

Add 200-400 parts by weight of pure water to the paste and gentle heating for boiling over 40-60 min;

and after boiling, filter to obtain a supernatant as a finished mouthwash product.

The mouthwash provided in the present invention has an effect in counteracting allergies, treating periodontes, treating oral ulcers, removing ozostomy, removing dental plaque, inhibiting ozostomy and cleaning the oral cavity.

For use, the above mouthwash only needs to be diluted with 10-20 times clear water and is then placed in the mouth, with movement of the two cheeks and the lip, a sufficient wetting of the teeth and gums with the allows clear water and every part of the oral cavity is repeatedly washed with water power.

The present invention is described in more detail by the following examples.

Examples 1-5 Examples 1-5 are used to illustrate the mouthwash provided by the present invention.

The filter membrane for filtration in Examples 1-5 preferably has a pore diameter of 0.45 μm.

According to the above ratios, the mouthwashes 1-5, which contain green tea in Examples 1-5, are obtained and are shown in Table 1.

Table 1

example Flos Sophorae (G) Agastache rugosa (G) Plantains Herb (G) green tea (G) Long-haired Antenoron Herb (g) Pomegranate peel (g) ethanol (G) salt (G) example 1 200 200 60 200 200 200 0 0 Example 2 250 250 60 200 200 200 30 5 Example 3 280 250 70 200 300 300 40 8th Example 4 280 260 70 300 300 400 50 10 Example 5 300 300 80 400 400 400 0 0

CH 714 586 A2

Experimental Examples 1-5 Experimental Examples 1-5 serve to illustrate dental health care and protective effects of the mouthwash provided by the present invention.

(1) Alleviation of oral mucosal allergy 150 male and female participants (in the age group of 25-40) with the symptom of oral mucosal allergy in different degrees of severity are selected and arbitrarily divided into five groups, with 30 patients per group. The mouthwash according to the invention is used in each of the five groups for a week and then the effects are determined, whereby, compared to a state before use of the mouthwash, the test participant whose allergy symptom has completely disappeared is marked as O, the test participant whose allergy symptom has been considerably alleviated , is marked as Δ and the subject whose allergy symptom showed no significant relief was marked as X, and the health effects are shown in Table 2.

Table 2

Effects group (number of participants)

Ο Δ X

1 19 8th 3 2 20 6 4 3 23 5 2 4 22 7 1 5 21 4 5

From the experimental results of the above experimental examples, it can be seen that the present invention makes sufficient use of the health-promoting effects of green tea to maintain the normal function of the oral mucosa, together with traditional Chinese medicinal ingredients from Agastache rugosa and long-haired Antenoron herb has a comprehensive pharmaceutical effect. When focusing on studies, the inventor found that the green tea can produce a chemical substance that can promote desensitization of the oral mucosa, the chemical substance can promote the absorption of water and nutrient on the outer surface of the oral mucosa by the oral mucosa, and can improve cell vitality to continue to achieve the technical effects of contributing to desensitization of the oral mucosa and counteracting allergy. The practical field test shows that after using the above mouthwash of the present invention for over a week, the allergy symptom of the oral mucosa can be effectively alleviated or disappear, thereby further meeting the anti-anaphylaxis requirements of the patients with oral mucosal allergy to the maximum extent.

(2) Relief from periodontitis 150 male and female patients (in the age group from 20-35) with the symptom periodontitis in different degrees of severity are selected and arbitrarily divided into five groups, with 30 patients per group. The mouthwash according to the invention is used in each of the five groups for a week and then the effects are determined, whereby, compared to a state before using the mouthwash, the test participant whose periodontitis symptom has completely disappeared is marked as O, the test participant whose periodontitis symptom has been considerably alleviated is marked as Δ and the subject whose periodontitis symptom showed no significant relief is marked as X and the health-promoting effects are shown in Table 3.

Table 3

group Effects (number of patients) 0 Δ X 1 18 10 2 2 19 8th 3 3 22 6 2

CH 714 586 A2

group Effects (number of patients) 0 Δ X 4 20 8th 2 5 17 8th 5

From the experimental results of the above experimental examples, it can be seen that the present invention makes sufficient use of the health benefits of antiphlogosis and bacteriostasis from green tea, the antiseptic and anti-inflammatory effects by combining Flos Sophorae and traditional Chinese medicine such as Agastache rugosa, which Effectively relieves symptoms of swelling and pain in the gums and gum congestion and continues to achieve the technical effects of relieving and treating periodontitis.

(3) Alleviation of mouth ulcer: 150 male and female subjects (in the age group of 20-40) are selected and arbitrarily divided into five groups, with 30 subjects per group. The mouthwash according to the invention is used in each of the five groups for a week and then the effects are determined, whereby, compared to a condition before use of the mouthwash, the test participant whose mouth ulcer symptom has completely disappeared is marked as O, the test participant whose oral ulcer symptom has been considerably alleviated , is marked as Δ, and the subject whose mouth ulcer symptom showed no significant relief is marked as X, and the health effects are shown in Table 4.

Table 4

Effects group (number of participants)

Ο Δ X

1 16 10 4 2 19 8th 3 3 25 4 1 4 22 4 4 5 19 10 1

From the experimental results of the above experimental examples, it can be seen that, with regard to the treatment of oral ulcer, the present invention has excellent technical effects of treatment and relief. The present invention sufficiently exerts the technical effect of a repair factor produced by the combined effect of Flos Sophorae, Agastache rugosa, plantane herb and green tea and offers good technical support for the rapid relief and healing of mouth ulcers. After the test participants used the mouthwash according to the invention, the effectiveness is further improved compared to the prior art and the treatment requirement for patients with oral ulcer can be met to the maximum extent. A short-term application of the mouthwash can have the technical effect that an ulcer wound no longer hurts, the skin layer cells of the ulcer wound can be repaired after 3-4 days of use, the wound can heal completely within a week and the mouthwash according to the invention has no toxic effect and none Has side effect.

(4) Alleviation of Ozostomy 150 male and female participants (in the age group of 20-40) with ozostomy in different degrees of severity are selected and arbitrarily divided into five groups, with 30 participants per group. The mouthwash according to the invention is used in each of the five groups for a week and then the effects are determined, whereby, compared to a state before use of the mouthwash, the test participant whose ostomy has completely disappeared is marked as O, the test participant whose ozostomy was considerably alleviated , is marked as a and the subject whose ozostomy showed no significant relief is marked as x, and the health effects are shown in Table 5.

Table 5

CH 714 586 A2

Effects group (number of participants)

Ο Δ X

1 16 10 4 2 18 8th 4 3 22 6 2 4 20 9 1 5 19 6 5

The present invention takes sufficient advantage of the technical effect resulting from green tea, effectively kills harmful bacteria that tend to cause bad breath in the oral cavity, and provides effective technical support for alleviating and eliminating ostostomy. The addition of pomegranate peel also helps to refresh the oral cavity and destroy the environment for the growth of harmful bacteria that tend to cause bad breath, and provides further technical support for eliminating bad breath in the oral cavity. The foregoing experiments show that the present invention has the technical effect of effectively relieving and eliminating ozostomy.

(5) Alleviation of tooth plaque removal and teeth whitening 150 male and female test participants (in the age group of 20-45) with the symptom tooth plaque and yellow teeth are selected and arbitrarily divided into five groups, with 30 test participants per group , The mouthwash according to the invention is used in each of the five groups for a week and then the effects are determined, whereby, compared to a state before use of the mouthwash, the test participant whose tooth plaque has completely disappeared is marked as O, the test participant whose tooth plaque has been considerably alleviated , is marked as Δ, and the subject whose dental plaque was not significantly relieved is marked as X, and the health effects are shown in Table 6.

Table 6

Effects group (number of participants)

Ο Δ X

1 18 9 3 2 19 8th 3 3 24 5 1 4 21 8th 1 5 17 9 4

When concentrating on investigations, the inventor found that the soup boiled from green tea also has the technical effect of removing tooth plaque. The present invention makes sufficient use of the above technical effect, inhibits the generation of dental plaque and effectively eliminates dental plaque and achieves the technical effect of promoting tooth whitening. The experiments show that after long-term use of the above mouthwash according to the invention, the dental plaque can be effectively removed; and that after short-term use, the effectiveness of removing dental plaque can be further improved compared to the prior art.

Claims (5)

claims 1. Green tea-containing mouthwash, which comprises by weight: Flos Sophorae 20-30, Agastache rugosa 20-30, plantane herb 6-8, green tea 20-40, long-haired Antenoron herb 20-40 and pomegranate peel 20-40; the mouthwash is made by the following steps: Mixing and grinding the raw materials to obtain a paste to be used; Add 200-400 parts by weight of pure water to the paste and gentle heating for boiling over 40-60 min; and after boiling, filter to obtain a supernatant as a finished mouthwash product. CH 714 586 A2 2. Mouthwash according to claim 1, which comprises, by weight: Flos Sophorae 25, Agastache rugosa 25, plantane herb 6, green tea 20, long-haired Antenoron herb 20 and pomegranate skin 20. 3. Mouthwash according to claim 1, which comprises by weight: Flos Sophorae 28, Agastache rugosa 25, plantane herb 7, green tea 20, long-haired Antenoron herb 30 and pomegranate peel 30. 4. Mouthwash according to claim 1, which comprises, by weight: Flos Sophorae 28, Agastache rugosa 26, plantane herb 7, green tea 30, long-haired Antenoron herb 30 and pomegranate peel 40. 5. Mouthwash according to any one of claims 1-4, which further comprises by weight: ethanol 0.5-1 and table salt 3-5.