KR20180079959A - Mouthwash containing green tea - Google Patents

Abstract

The present invention discloses a mouthwash comprising 20 to 30 parts by weight of cow bezoar, 20 to 30 parts by weight of Perilla frutescens, 6 to 8 parts by weight of Bupleurum falcatum, 20 to 40 parts by weight of green tea, 20 to 40 parts by weight of Artemisia capillaries, and 20 to 40 parts by weight of Chrysanthemum morifolium Ramat. A method of producing the mouthwash comprises the steps of: mixing raw materials to obtain a mixture and pulverizing the mixture to obtain a paste to be used; adding 200 to 400 parts by weight of pure water to the paste, and weakly heating the paste in water to boil down the paste in water for 40 to 60 minutes to obtain a boiled-down material; and filtering the boiled-downed material to obtain a supernatant as a mouthwash final product. The mouthwash provided in the present invention has effects in allergy tolerance, treatment of periodontitis, treatment of mouth ulcer, removal of bad breath, removal of dental plaque, halitosis control and oral cleaning, and additionally has special effects for treating various kinds of oral diseases.

Description

MOUTHWASH CONTAINING GREEN TEA}

The present invention relates to a green tea-containing mouthwash.

In the prior art, the oral cleanser has a high or low concentration, the high-concentration oral cleanser is used after dilution with water, and the low-concentration oral cleanser can be used directly. Prior art oral cleansers are typically classified as follows:

1. Fluoride-containing mouthwash

Most fluoride-containing mouthwashes contain 0.05% sodium fluoride and can provide additional fluoride to the person in need. Although fluorine-containing mouthwashes can help relieve plaque, excessive intake of fluorine-containing compounds can be detrimental to health.

2. Dental biofilm mouthwash

These mouthwashes help to reduce the chance of gingival inflammation by preventing accumulation of dental biofilm. This mainly includes triclosan, thymol, hexadecyl chloride and the like. However, more facts indicate that these mouthwashes can not prevent periodontal disease.

3 Inhibitive mouthwashes of the septic biofilm:

Chlorhexidine gluconate was found to effectively inhibit the growth of dental biofilm and prevent periodontal disease. However, when used for a long time, tooth stains easily settle on the surface of the teeth, affect the taste, and cause recurrent apta.

4. Anti-allergic mouthwash

The major chemical components of these mouthwashes, such as potassium nitrate, cause the microtubules of the dentin to be closed, thereby reducing tooth allergy. However, anti-allergic mouthwashes should not be used for extended periods of time.

5. Herbal mouthwash

Most herbal mouthwashes are extracted from tea leaves, are rich in vitamins, have sterilization and anti-wrinkle effects, and have high antioxidant properties. The catechins contained in the catechins can penetrate into the tooth clearance and the tooth cavities, effectively inhibiting the bacteria and protecting the oral health.

6. Traditional herbal medicine herbal mouthwash

The mouthwash is pharmaceutically usable and purified from pure edible Chinese herb medicine. It mainly contains leaf blades, perfume oils, cloves, and does not contain a wide range of sterilizing chemicals such as alcohol, antibiotics, and triclosan. It has traditional traditional medicinal culture characteristics and can be used for both sexes and pregnant women.

Regular green tea is 99.9% water, provides 1 calorie per 100 ml serving, has no significant nutrient content (table), and contains phytochemicals such as polyphenols and caffeine. The polyphenols present in green tea include epigallocatechin gallate (EGCG), epicatechin gallate, epicatechin and flavanol.

There have been many claims about the health benefits of green tea, but human clinical studies have failed to provide conclusive evidence of random effects. In 2011, scientists released reports of claims about health effects at the request of the European Commission: in general, they found that what was claimed for green tea was not supported by sufficient scientific evidence. While the average content of flavonoids and catechins in a cup of green tea was higher than that present in the same volume of other food and beverage items traditionally thought to promote health, flavonoids and catechins failed to demonstrate biological effects in humans.

The present invention aims at overcoming the disadvantages of the prior art oral care cleansing agents in health care performance and chooses green tea as a main raw material and combines the effects of traditional medicinal materials with research achievements of modern pharmacology, The present invention provides a mouth rinse which is characterized in that it has properties, can prevent oral diseases, and has an excellent tooth-gain effect.

For this reason, the present invention relates to a medicinal composition comprising Bezoar 20-30, Perilla 20-30, Radix Bupleuri 6-8, Green tea 20-40, Capillary artemisia 20-40 And chrysanthemums 20-40,

Mixing and grinding the raw materials to obtain a to-be-used paste;

200-400 parts by weight of pure water is added to the paste and heated to mild for 40-60 minutes;

Followed by filtration to obtain a supernatant as a mouthwash end product.

In case of use, the mouthwash is diluted with 10-20 times clear water, then put in mouth, clear water is brought into contact with the teeth and gums thoroughly by the movement of both balls and lips, Let it wash repeatedly by force.

Green Tea: It is one of the main tea of China; Refers to beverages produced by collecting (not fermenting), securing, re-molding and drying young leaves or shoots of tea trees.

Other features and advantages of the present invention will be described in detail in the following sections of specific embodiments.

The mouthwash provided in the present invention has an effect in allergy resistance, periodontal treatment, oral ulcer treatment, bad breath removal, plaque removal, bad breath suppression and oral cleaning.

Without losing the generality, the present invention includes on a weight basis a bouillon 20-30, a perilla leaf 20-30, a teico 6-8, a green tea 20-40, a capillary artemisia 20-40 and a chrysanthemum 20-40;

Mixing and grinding raw materials to obtain a paste to be used;

200-400 parts by weight of pure water is added to the paste and heated to mild for 40-60 minutes;

Which is then filtered to obtain a supernatant as a mouthwash end product.

The mouthwash provided in the present invention has an effect in allergy resistance, periodontal treatment, oral ulcer treatment, bad breath removal, plaque removal, bad breath suppression and oral cleaning.

In case of use, the mouthwash is diluted with 10-20 times clear water, then put in mouth, clear water is brought into contact with the teeth and gums thoroughly by the movement of both balls and lips, Let it wash repeatedly by force.

The present invention is described in more detail by the following examples.

Examples 1-5 :

Examples 1-5 are used to illustrate the mouthwash provided by the present invention.

Preferably, the filter membrane for filtration in Examples 1-5 has a pore diameter of 0.45 mu m.

According to the above ratio, the green tea-containing oral cleanser 1-5 of Example 1-5 was obtained and is shown in Table 1 below.

Experimental Examples 1-5

Experimental Examples 1-5 are used to illustrate oral health care and protective effects of the mouthwash provided by the present invention.

(1) relief for oral mucosa allergy

A total of 150 male and female subjects (age range 25-40 years) with varying degrees of oral mucosal allergies were selected and randomly divided into 5 groups with 30 patients in each group. The oral cleaning agent of the present invention was used in five groups for one week, and the effects were observed. The results were compared with those before use of the oral cleanser, and the results were shown as ○ for those who had completely lost allergy symptoms, The results are shown in Table 2 below. The results are shown in Table 2 below. ≪ tb > < TABLE > Id = Table 2 Columns = 2 < tb >

group
Effect (number of experiment) O △ X One 19 8 3 2 20 6 4 3 23 5 2 4 22 7 One 5 21 4 5

From the experimental results of the above experimental examples, the present invention fully utilizes the health care effect of green tea which maintains the normal function of the oral mucosa, and in order to exhibit a comprehensive pharmaceutical effect, the traditional medicinal herb ingredients of the perilla leaf and capillary artemisia . In experiments, the present inventors have found that green tea can produce chemicals that can promote oral mucosal de-allergization, and chemicals can promote absorption of water and nutrients on the outer surface of oral mucosa by oral mucosa , It has been found that it is possible to improve the cell viability, thereby helping the oral mucosa to be hypoallergenic and further achieving the technical effect of enduring allergy. Practical field testing indicates that the allergy symptoms of the oral mucosa after effective use of the mouthwash of the present invention for one week can be effectively relieved or disappeared to the greatest extent satisfying the antianaphylaxis requirement of the patient with oral mucosa allergy .

(2) Relaxation for periodontitis

150 male and female patients (age range 20-35 years) with varying degrees of periodontal symptoms were selected and randomly divided into 5 groups with 30 patients per group. The effect of the mouthwash according to the present invention was observed in five groups for one week each, and the effect was observed. Compared to the state before use of the mouthwash, the test was marked with an o for the completely disappeared periodontitis, Patients with palliative symptoms are marked with " DELTA ", and periodontitis symptoms are marked with " x " for patients who do not have noticeable palliative care.

group
Effect (number of patients) O △ X One 18 10 2 2 19 8 3 3 22 6 2 4 20 8 2 5 17 8 5

From the experimental results of the above Experimental Example, the present invention fully utilizes the health care effect of the green tea and the bacteriostatic action, achieves the effect of disinfection and anti-inflammation by combining the bamboo and traditional traditional medicines such as perilla leaves, It is possible to effectively alleviate symptoms of gum bleeding, and further achieve the technical effects of palliation and treatment of periodontitis.

(3) Mitigation of dental ulcers

150 male and female subjects (age range 20-40 years) were selected and randomly divided into 5 groups with 30 subjects per group. The effect of the mouthwash according to the present invention was observed in five groups for one week each, and the effect was observed. The results were compared with those before use of the oral cleanser. The results are shown in Table 4 below. The results are shown in Table 4, and the results are shown in Table 4 below.

group
Effect (number of experiment) O △ X One 16 10 4 2 19 8 3 3 25 4 One 4 22 4 4 5 19 10 One

From the experimental results of the above Experimental Examples, it can be seen that the present invention has excellent technical effects of treatment and alleviation in the treatment of dental ulcers. The present invention fully demonstrates the technical effect of the restorative factors produced by the mixing action of bamboo, perilla leaves, green tea and green tea, and provides strong technical support for rapid relief and healing of dental ulcers. After using the mouthwash of the present invention by the experimenter, the efficacy has been further improved over the prior art and the therapeutic requirements for dental ulcer patients can be met to a maximum extent. Short-term application of mouthwashes is no longer painful for ulcer wounds, ulcer wound skin layer cells can be restored 3-4 days after application, wounds can be completely healed within one week, and mouthwashes of the invention are toxic And technical effects without side effects can be achieved.

(4) Reduction of bad breath

150 male and female subjects (age range 20-40 years) with varying degrees of bad breath were selected and randomly divided into 5 groups with 30 subjects per group. The mouthwashes of the present invention were used in five groups for one week, and the effects were observed. The results were compared with those before use of the mouthwash, The results are shown as △ for the experimenter and × for the experimenter who does not have noticeable relief of bad breath, and the health care effect is shown in Table 5 below.

group
Effect (number of experiment) O △ X One 16 10 4 2 18 8 4 3 22 6 2 4 20 9 One 5 19 6 5

The present invention fully exploits the technical effects generated from green tea, effectively kills noxious bacteria that are prone to generate severe odors in the mouth, and provides effective technical support for relief and removal of bad breath. In addition, the addition of chrysanthemums refreshes the mouth, helps to destroy the growth environment of the noxious bacteria that are prone to generate a strong odor, and provides additional technical support to eliminate the intense odor in the mouth. This experiment shows that the present invention has a technical effect of effectively mitigating and eliminating halitosis.

(5) removing plaque and teeth whitening

A selection of 150 male and female subjects (age range 20-45 years) with varying degrees of plaque and yellow teeth were randomly divided into 5 groups with 30 subjects per group. The mouthwashes of the present invention were used in 5 groups for 1 week each, and the effects were observed. The results were compared with those before use of the mouthwash, The results are shown in Table 6 below. The results are shown in Table 6 below.

group
Effect (number of experiment) O △ X One 18 9 3 2 19 8 3 3 24 5 One 4 21 8 One 5 17 9 4

As a result of experiments, the present inventors found that the liquid from green tea has a technical effect of removing plaque. It has been found that the present invention fully exploits the technical effects, inhibits the formation of plaque, effectively removes plaque, and achieves the technical effect of promoting tooth whitening. Experiments have shown that post-application post-application of the mouthwash according to the present invention can be effectively removed and that the effect of post-application post-application tooth removal can be further improved over the prior art.

Claims (5)

As a green tea-containing mouthwash,
On the basis of parts by weight, bezoar 20-30, perilla leaves 20-30, Radix Bupleuri 6-8, green tea 20-40, capillary artemisia 20-40 and chrysanthemum 20-40 / RTI >
Mixing and grinding the raw materials to obtain a to-be-used paste;
200-400 parts by weight of pure water is added to the paste and heated to mild for 40-60 minutes; And
Followed by filtration to obtain the supernatant as a mouthwash end product. The mouthwash according to claim 1, comprising, on a weight basis, a mixture of bouillon 25, perilla leaf 25, Seiho 6, green tea 20, capillary artemisia 20 and chrysanthemum 20. The mouthwash according to claim 1, comprising, on a weight basis, a mixture of a boule 28, a perilla leaf 25, a seal 7, a green tea 20, a capillary artemisia 30 and a chrysanthemum 30. The mouthwash according to claim 1, comprising, on a weight basis, a mixture of broom 28, perilla leaves 26, Seiho 7, green tea 30, capillary artemisia 30 and chrysanthemum 40. The mouthwash according to any one of claims 1 to 4, further comprising, on a weight basis, ethanol 0.5-1 and edible salt 3-5.