CN110151916A - A kind of ointment and preparation method thereof for treating onychomycosis - Google Patents
A kind of ointment and preparation method thereof for treating onychomycosis Download PDFInfo
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Abstract
A kind of ointment and preparation method thereof for treating onychomycosis, it is related to onychomycosis treatment technology field.A kind of ointment that treating onychomycosis is made of following raw material: cloves, Herba Menthae powder, borneol, cortex cinnamomi, perilla leaf, kuh-seng, the bletilla striata, Qiu Shi, benzoic acid, salicylic acid, lanolin, lactic acid, glacial acetic acid, distilled water.Taking above-mentioned raw materials to carry out preparation according to a kind of preparation method of ointment for treating onychomycosis by metering proportion can be obtained a kind of ointment for treating onychomycosis.After by adopting the above technical scheme; the invention has the benefit that it can effectively treat tinea of feet and hands caused by onychomycosis, corn and viral verruca (being only limitted to hand and foot) and local fungal infection; have many advantages, such as that treatment time is short, curative effect is high, without side-effects, easy to use, at low cost; onychomycosis can be thoroughly eradicated, significant effect does not recur; and its preparation method is simple; raw material sources are extensive, wide market, are suitble to large-scale production.
Description
Technical field
The present invention relates to onychomycosis treatment technology fields, and in particular to a kind of ointment for treating onychomycosis and its preparation side
Method.
Background technique
Onychomycosis is a kind of skin disease common disease, frequently-occurring disease, and ash refers to (toe) first, medically also known as onychomycosis, is invaded by fungi
Attack and cause the lesion for referring to the infection of (toe) first and occurring.Clinical manifestation is nail body deformation, thickens, uneven, nail body is coarse, nothing
Gloss or discoloration, nail body incompleteness etc..Onychomycosis disease incidence is high, and infectiousness is strong, and onychomycosis not only influences brothers' appearance, can also cause hand
Tinea, tinea pedis, ringworm of the body and other fungal infectious diseases.And many inconvenience can be brought after suffering from onychomycosis, and such as: one, shadow
It rings beautiful;Two, work is limited;Three, daily life is influenced;Four, abnormal mind obstacle is generated;Five, complication is more;Six, become people
Body infection sources etc. becomes the puzzlement of many people.Existing technology treats onychomycosis on the market at present, has several schemes: one,
For oral administration antifungal (Sporanox, Yi Qukang frustrate, griseofulvin);Two, by physical damage (pulling out first).But use endo-medicine
Method treatment onychomycosis side effect it is big, the impariment of the liver is dirty, kidney, larger to the damage of human body, and easily recurs, and uses
The method for pulling out first is too painful, is easy to deform nail.
Summary of the invention
In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of ointment for treating onychomycosis and its
Preparation method, caused by it can effectively treat onychomycosis, corn and viral verruca (being only limitted to hand and foot) and local fungal infection
Tinea of feet and hands has many advantages, such as that treatment time is short, curative effect is high, without side-effects, easy to use, at low cost, can thoroughly eradicate ash and refer to
First, significant effect do not recur, and its preparation method is simple, and raw material sources are extensive, wide market, are suitble to scale
Production.
To achieve the above object, the present invention is using following technical scheme: a kind of ointment that treating onychomycosis is by following heavy
Measure the raw material composition of number: 50-150 parts of cloves, 60-180 parts of Herba Menthae powder, 100-250 parts of borneol, 150-400 parts of cortex cinnamomi, purple perilla
170-340 parts of leaf, 130-300 parts of kuh-seng, 200-400 parts of the bletilla striata, 100-150 parts of Qiu Shi, 100-250 parts of benzoic acid, salicylic acid
100-350 parts, 50-200 parts of lanolin, 80-240 parts of lactic acid, 80-240 parts of glacial acetic acid, 300-1000 parts of distilled water.Its system
Preparation Method the following steps are included: the first step, by metering than take suitable cloves, Herba Menthae powder, borneol, cortex cinnamomi, perilla leaf, kuh-seng,
The bletilla striata, Qiu Shi, benzoic acid, salicylic acid, lanolin, lactic acid, glacial acetic acid and distilled water;Step 2, by kuh-seng, cloves, the bletilla striata, purple
Perilla leaf, cortex cinnamomi and Herba Menthae powder, which are put into wooden barrel, to stir evenly, and obtains mixture A;Step 3 uses autumn petrochemical industry water in mixture A
After pour into mixture A and stir evenly, obtain mixture B;Mixture B is stood 48 hours by step 4;Step 5 will be stood
Mixture B taking-up semi-finished product afterwards, which are put on pot, to tile, and obtains paste after Steam by water bath 20min;Step 6, by borneol, wool
Rouge, lactic acid, benzoic acid, salicylic acid and glacial acetic acid, which are put into vessel, to stir evenly, and obtains mixture C;Step 7, by mixture C
It merges and stirs with paste, complete patent medicine.
The glacial acetic acid is 30% glacial acetic acid.
After adopting the above technical scheme, the invention has the following beneficial effects: it can effectively treat onychomycosis, corn and viral verruca
Tinea of feet and hands caused by (being only limitted to hand and foot) and local fungal infection, have treatment time is short, curative effect is high, it is without side-effects, make
The advantages that with facilitating, being at low cost, onychomycosis can be thoroughly eradicated, significant effect does not recur, and its preparation method is simple,
Raw material sources are extensive, wide market, are suitble to large-scale production.
Specific embodiment
Embodiment 1
Present embodiment the technical solution adopted is that: a kind of ointment that treating onychomycosis by following parts by weight original
Material composition: 50 parts of cloves, 60 parts of Herba Menthae powder, 100 parts of borneol, 150 parts of cortex cinnamomi, 170 parts of perilla leaf, 130 parts of kuh-seng, the bletilla striata 200
Part, 100 parts of Qiu Shi, 100 parts of benzoic acid, 100 parts of salicylic acid, 50 parts of lanolin, 80 parts of lactic acid, 80 parts of glacial acetic acid, distilled water 300
Part.Its preparation method is the following steps are included: the first step, by metering than taking suitable cloves, Herba Menthae powder, borneol, cortex cinnamomi, purple perilla
Leaf, kuh-seng, the bletilla striata, Qiu Shi, benzoic acid, salicylic acid, lanolin, lactic acid, glacial acetic acid and distilled water;Step 2, by kuh-seng, fourth
Perfume, the bletilla striata, perilla leaf, cortex cinnamomi and Herba Menthae powder, which are put into wooden barrel, to stir evenly, and obtains mixture A;Step 3, in mixture A
It is stirred evenly with being poured into mixture A after autumn petrochemical industry water, obtains mixture B;Mixture B is stood 48 hours by step 4;Step
Five, the mixture B taking-up semi-finished product after standing are put on pot and are tiled, obtain paste after Steam by water bath 20min;Step 6, will
Borneol, lanolin, lactic acid, benzoic acid, salicylic acid and glacial acetic acid, which are put into vessel, to stir evenly, and obtains mixture C;Step 7,
By mixture C and paste fusion stirring, patent medicine is completed.
The glacial acetic acid is 30% glacial acetic acid.
Cloves alias: flos caryophylli, great Hua cloves, lilac, Fructus Caryophylli.Can middle benefit gas drop it is inverse, it is supporing yang to warm up kidney, the analgesic of lower gas.
For stomach cold distending pain, numbness pain, colic, hiccup, vomiting and diarrhoea, halitosis, toothache, indigestion, acute or chronic gastritis, hypogona dism etc.
Disease.Modern study has promotion gastric secretion, enhances eupepsy, mitigates nausea and vomiting, alleviates abdominal bloating, also eases pain, is anti-
The effects of scorching, anticonvulsion, antibacterial, antithrombus formation, anti diar rhea, cholagogue and anti anoxia.Clinically choosing can be used to treat children
Diarrhea, ringworm of the body, tinea pedis etc..
The bletilla striata is orchid family herbaceos perennial, the dry tuber of the bletilla striata, surface canescence or yellow-white, there is fine wrinkle,
There is the stem trace of protrusion above, also there is the trace for connecting another stem tuber below.Centered on stem trace, several brown concentricities, ring
The dotted mark of fibrous root of upper residual brown.Matter is hard, is not easily broken.Section off-white color, translucent, cutin sample, it is seen that be dispersed in dotted
Vascular bundle.Coarse powder is met water and is expanded, and has significant stick-slip sense, and infusion is in colloid sample.It is odorless, bitter, the toughness chewed.With a
Greatly, full, color is white, translucent, the solid person of matter is preferred.Its bitter, sweet, puckery, cold nature, return lung, liver, stomach meridian.Have astringing to arrest bleeding,
The function of detumescence and promoting granulation, for all cards of interior external hemorrhage and carbuncle swells, scald, rhagadia manus et pedis, anal fissure etc..
Herba Menthae powder, the Classification system popular name (Mentha haplocalyx Briq.) are Lamiaceae plant " lunar caustic grass ",
Belong to other drying herbs.Acrid flavour, it is cool in nature.Return lung, Liver Channel have diverging wind-heat, clearing throat, promoting eruption removing toxic substances, soothing liver-qi stagnation
With it is antipruritic and other effects.Peppermint has effects that stimulation nervous centralis, and acting on skin has bright sense and creeping chill simultaneously, it is refreshing to feeling
There are inhibition and paralysis again through tip;Therefore, it can be used as counter-stimulus and cutaneous stimulant.Both had to pruitus anti-
Allergy and itching-relieving action, and there is apparent alleviation and analgesic activity to neuralgia and rheumatic arthritis.Antiphlogistic antibacterial.Peppermint pair
Bite by mosquitos skin plays the role of desensitization, anti-inflammatory and antibacterial;Also there are apparent cough-relieving, anti-inflammatory and antibacterial work to the infection of the upper respiratory tract
With;There are swelling and pain relieving, antiphlogistic antibacterial to hemorrhoid, anal fissure.
Borneol, Chinese medicine name, acrid flavour, hardship, thoughts of returning home warp, the spleen channel and lung channel have and lead to all keys, dissipate stagnated fire, inducing resuscitation, go screen
The effect of improving eyesight, swelling and pain relieving.For apoplexy lockjaw, pyreticosis coma, red eye, swell pain, sore throat aphtha, sore swell and ache curative, after bursting not
It holds back, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, tympanitis, enterobiasis etc..Modern pharmacology research shows that borneol has analgesic, anti-corrosion, resists
Inflammation, antifertility, calmness, the effects of resisting myocardial ischemia.Mainly play detumescence convergence wound in this side, for treating because of first
Refer to that (toe) first surrounding skin is red and swollen caused by tinea.
Perilla leaf is the drug that chill inducing diaphoresis is used in Chinese medicine.Chill inducing diaphoresis is exactly to aversion to cold, fever, headache, cough
The patient of symptoms such as cough, have a sore throat plays the role of sweating chill.In addition, it can be disappeared after being affected by the cold with ventilating
Change bad, uncomfortable in chest, belch, constipation etc., perilla leaf can play the role of open chest, pleasant, preventing or arresting vomiting.In addition to this, the most frequently used
There are also solution fish, shrimp, crab poison effect.If having fish that is unclean or rotting, shrimp, crab etc. causes diarrhea, vomiting,
By drinking common perilla leaf water, can play the role of mediating fish, shrimp, crab toxicity.
Kuh-seng alias: wild Chinese scholartree, Hao Hanzhi, matrine, bone, Chinese scholartree, Albizzia kalkora, matrine, chuanshentong, phoenix claw.It is grown on sea
1500 meters of area is pulled out, more lifes are in hillside, sand ground, Cao Po, spinney and near field, at present not yet by manually introducing a fine variety cultivation
Training.The major functions: heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, hematochezia, jaundice urodialysis, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema is wet
Sore, pruitus, castor;Trichomonas vaginitis etc. is controlled outside.
The effect of cortex cinnamomi, is called beautiful osmanthus, male osmanthus, bacterium osmanthus, cylinder osmanthus, cortex cinnamomi be mends fire supporing yang, let the fire back to its origin, eliminating cold to stop pain,
Blood circulation, the effect of cortex cinnamomi are to control impotence, palace cold, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, menostasis, dysmenorrhea, and cortex cinnamomi medication taboo is yin
The fire of deficiency type is prosperous, inner to have real heat, and blood-heat bleeding bleeding and pregnant woman, which prohibit, takes cortex cinnamomi, and cortex cinnamomi fears red halloysite.
Qiu Shi (Prepared Salt) is a kind of title of drug, and alias: sal praeparatus, autumn ice, depositum urinae praeparatum belong to calcification and close
Species.Cure mainly the symptoms such as thin thin, the hectic fever due to yin labor heat of consumptive disease, cough, hemoptysis, abscess of throat, spermatorrhea.The Britain of Chinese Taoist coition medicine
Chinese medicine " Qiu Shi " is classified as one of 26 inventions of ancient Chinese science and technology by scholar's Needham, Noel Joseph Terence Montgomery.
Effect of the lanolin in clinic is mainly reflected in applies together with vaseline, can increase the penetrating of vaseline
Property, simultaneously as lanolin can also nurse skin, especially for dry skin, can effectively keep the skin wet,
The loss of moisture is prevented, can be anti-oxidant, harmful acidic materials can be removed.It, can be with because containing vitamin E
The elasticity of skin is improved, delays senescence, the regeneration of skin can also be promoted, there is the energy for promoting cytothesis for damaged skin
Power can resist some harmful substances, protect skin.
Lactic acid CH3CH (OH) COOH.Medical aspect: disappeared in the places such as ward, operating room, laboratory using lactic acid steam
Poison can effectively kill the bacterium in air, play reduction disease, reach the purpose for improving health;It is widely used as in terms of medicine
Preservative, carrier agent, cosolvent, pharmaceutical preparation, pH adjusting agent etc.;Lactic acid, which can be formulated directly into drug or daily health products, to be made
With;Beautiful privates shower cream of such as spoiling is the formula that European expert develops, and manufactures slowly, joined for mature women's Vaginal lactobacilli
Lactic acid composition safeguards the self-cleaning action of vagina.Save muscle vitality and antifatigue restrictive function.
Benzoic acid C7H602.Also known as benzoic acid is that a hydrogen on phenyl ring is replaced the chemical combination formed by carboxyl (- COOH)
Object.Benzoic acid is generally used frequently as drug or preservative, plays the role of inhibiting fungi, bacterium, fungus growth, usual when medicinal
It applies on the skin, to treat the skin disease of tinea class.
Salicylic acid C7H603.Salicylic acid is a kind of fat-soluble organic acid.Salicylic acid (aspirin and many anodyne
In ingredient) be used to reduce the long-term concurrent cardiopathic risk of diabetic in clinical test.Newest research is to require
All type 1 diabetes breath persons for having had heart disease will take, while salicylic treatment is also proposed as prevention simultaneously
The method for sending out disease.
Glacial acetic acid.Treat disease: corn, wart effect: the product various concentration is to treat various superficial skin fungus
Infection, the treatment of the lavation surface of a wound and corn, wart.
Embodiment 2
The present embodiment and the difference of embodiment 1 are: it is made of the raw material of following parts by weight: 100 parts of cloves, thin
110 parts of lotus powder, 150 parts of borneol, 300 parts of cortex cinnamomi, 150 parts of perilla leaf, 200 parts of kuh-seng, 300 parts of the bletilla striata, 120 parts of Qiu Shi, benzene first
Sour 180 parts, 250 parts of salicylic acid, 150 parts of lanolin, 140 parts of lactic acid, 140 parts of glacial acetic acid, 500 parts of distilled water.Other raw material groups
It is same as Example 1 at, preparation method.
Embodiment 3
The present embodiment and the difference of embodiment 1 are: it is made of the raw material of following parts by weight: 150 parts of cloves, thin
180 parts of lotus powder, 250 parts of borneol, 400 parts of cortex cinnamomi, 340 parts of perilla leaf, 300 parts of kuh-seng, 400 parts of the bletilla striata, 150 parts of Qiu Shi, benzene first
Sour 250 parts, 350 parts of salicylic acid, 200 parts of lanolin, 240 parts of lactic acid, 240 parts of glacial acetic acid, 1000 parts of distilled water.Other raw material groups
It is same as Example 1 at, preparation method.
After adopting the above technical scheme, the invention has the following beneficial effects: it can effectively treat onychomycosis, corn and viral verruca
Tinea of feet and hands caused by (being only limitted to hand and foot) and local fungal infection, have treatment time is short, curative effect is high, it is without side-effects, make
The advantages that with facilitating, being at low cost, onychomycosis can be thoroughly eradicated, significant effect does not recur, and its preparation method is simple,
Raw material sources are extensive, wide market, are suitble to large-scale production.
The above is only used to illustrate the technical scheme of the present invention and not to limit it, and those of ordinary skill in the art are to this hair
The other modifications or equivalent replacement that bright technical solution is made, as long as it does not depart from the spirit and scope of the technical scheme of the present invention,
It is intended to be within the scope of the claims of the invention.
Claims (6)
1. a kind of ointment for treating onychomycosis, it is characterised in that it is made of the raw material of following parts by weight: a kind of ash for the treatment of refers to
The ointment of first is made of the raw material of following parts by weight: 50-150 parts of cloves, 60-180 parts of Herba Menthae powder, 100-250 parts of borneol, meat
Osmanthus 150-400 parts, 170-340 parts of perilla leaf, 130-300 parts of kuh-seng, 200-400 parts of the bletilla striata, 100-150 parts of Qiu Shi, benzoic acid
100-250 parts, 100-350 parts of salicylic acid, 50-200 parts of lanolin, 80-240 parts of lactic acid, 80-240 parts of glacial acetic acid, distilled water
300-1000 parts.
2. a kind of preparation method for the ointment for treating onychomycosis, it is characterised in that it presses metering ratio the following steps are included: the first step
Take suitable cloves, Herba Menthae powder, borneol, cortex cinnamomi, perilla leaf, kuh-seng, the bletilla striata, Qiu Shi, benzoic acid, salicylic acid, lanolin, cream
Acid, glacial acetic acid and distilled water;Kuh-seng, cloves, the bletilla striata, perilla leaf, cortex cinnamomi and Herba Menthae powder are put into wooden barrel and stir by step 2
It is even, obtain mixture A;Step 3 is stirred evenly with pouring into mixture A after autumn petrochemical industry water in mixture A, obtains mixture
B;Mixture B is stood 48 hours by step 4;Mixture B taking-up semi-finished product after standing are put on pot and tile by step 5,
Paste is obtained after Steam by water bath 20min;Borneol, lanolin, lactic acid, benzoic acid, salicylic acid and glacial acetic acid are put into device by step 6
It is stirred evenly in ware, obtains mixture C;Mixture C and paste fusion stirring are completed patent medicine by step 7.
3. a kind of ointment for treating onychomycosis according to claim 1, it is characterised in that it by following parts by weight original
Material composition: 50 parts of cloves, 60 parts of Herba Menthae powder, 100 parts of borneol, 150 parts of cortex cinnamomi, 170 parts of perilla leaf, 130 parts of kuh-seng, the bletilla striata 200
Part, 100 parts of Qiu Shi, 100 parts of benzoic acid, 100 parts of salicylic acid, 50 parts of lanolin, 80 parts of lactic acid, 80 parts of glacial acetic acid, distilled water 300
Part.
4. a kind of ointment for treating onychomycosis according to claim 1, it is characterised in that it by following parts by weight original
Material composition: 100 parts of cloves, 110 parts of Herba Menthae powder, 150 parts of borneol, 300 parts of cortex cinnamomi, 150 parts of perilla leaf, 200 parts of kuh-seng, the bletilla striata
300 parts, 120 parts of Qiu Shi, 180 parts of benzoic acid, 250 parts of salicylic acid, 150 parts of lanolin, 140 parts of lactic acid, 140 parts of glacial acetic acid, steaming
500 parts of distilled water.
5. a kind of ointment for treating onychomycosis according to claim 1, it is characterised in that it by following parts by weight original
Material composition: 150 parts of cloves, 180 parts of Herba Menthae powder, 250 parts of borneol, 400 parts of cortex cinnamomi, 340 parts of perilla leaf, 300 parts of kuh-seng, the bletilla striata
400 parts, 150 parts of Qiu Shi, 250 parts of benzoic acid, 350 parts of salicylic acid, 200 parts of lanolin, 240 parts of lactic acid, 240 parts of glacial acetic acid, steaming
1000 parts of distilled water.
6. a kind of ointment for treating onychomycosis according to claim 1, it is characterised in that: the glacial acetic acid is 30% ice
Acetic acid.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112107675A (en) * | 2020-11-05 | 2020-12-22 | 赵垒垒 | Chinese herbal medicine ointment for preventing and treating onychomycosis and preparation method thereof |
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CN1857493A (en) * | 2006-03-29 | 2006-11-08 | 刘湘东 | Antiseptic for preventing and treating tinea unguium and tinea of feet and hands |
CN103565914A (en) * | 2013-10-08 | 2014-02-12 | 高仓志 | Combined mixture of traditional Chinese and Western medicine for treating onychomycosis and paronychia |
US20190167744A1 (en) * | 2016-08-01 | 2019-06-06 | Angel GONZALEZ HERNANDEZ | Method for preparing product based on leaves of the sedum telephium plant for the treatment of nails infected with onychomycosis |
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CN1333052A (en) * | 2001-04-11 | 2002-01-30 | 吴诚 | Lotion for beriberi |
CN1857493A (en) * | 2006-03-29 | 2006-11-08 | 刘湘东 | Antiseptic for preventing and treating tinea unguium and tinea of feet and hands |
CN103565914A (en) * | 2013-10-08 | 2014-02-12 | 高仓志 | Combined mixture of traditional Chinese and Western medicine for treating onychomycosis and paronychia |
US20190167744A1 (en) * | 2016-08-01 | 2019-06-06 | Angel GONZALEZ HERNANDEZ | Method for preparing product based on leaves of the sedum telephium plant for the treatment of nails infected with onychomycosis |
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CN112107675A (en) * | 2020-11-05 | 2020-12-22 | 赵垒垒 | Chinese herbal medicine ointment for preventing and treating onychomycosis and preparation method thereof |
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