CN107929407A - A kind of ointment for treating adolescent acne and preparation method thereof - Google Patents

Abstract

The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；The traditional Chinese medicinal components are made of the raw material of following parts by weight：5~10 parts of 30~50 parts of kuh-seng, 20~30 parts of azedarach, 20~30 parts of pomegranate root, 20~30 parts of Cortex Phellodendri, 20~30 parts of peach root, 18~30 parts windproof, 18~30 parts of lotus leaf, 12~20 parts of alumen, 16~26 parts of the root of Dahurain angelica, 50~60 parts of camphor and whitish honey, the western medicine component is made of 30~50 parts of vaseline and 30~50 parts of salicylic acid；The ointment of the present invention has the effect of clearing heat-fire, detoxicating and resolving a mass, healing up sore and subduing swelling, cooling blood and dissolving stasis, nourishing the blood to expel wind, moist skin, remove hot gas in skin, malignant sore is dissipated, skin of moistening, dissipation skin chronic inflammation, exclude vivotoxin, Western medicine vaseline rapid osmotic is used cooperatively again, is treated both principal and secondary aspect of disease, the infringement problem of comprehensively solve adolescent acne and acne scars to skin, good absorption effect, it is evident in efficacy.

Description

A kind of ointment for treating adolescent acne and preparation method thereof

Technical field

The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of ointment of adolescent acne and preparation method thereof.

Background technology

Adolescent acne is a kind of a kind of relatively conventional disease for being apt to occur in face and chest and back.It is apt to occur in puberty man Female, in papulosquamous, is often accompanied by seborrhea after extruding, therefore is commonly called as " whelk ".Adolescent acne is more common in face, also occurs Behind thoracic dorsal top and omoplate, front, neck, buttocks etc., and adolescent acne does not disappear often for a long time, and old wound is not cured, newly Disease is sent out.Adolescent acne is pityriasis rubra papule to the basic lesions of skin, shows as blackhead and Whiteheads；If generation is scorching Disease, acne are rubescent, and papilla just occurs in top, and at this moment appearance will be had an impact, and great psychology is caused to young man Pressure and mental suffering.

The cause of disease of acne is complex, wherein, endocrine factors, infective agent, dietary factor etc. are in the morbidity of acne Play an important role.This disease of western medical treatment generally according to symptom, suit the medicine to the illness respectively give XCJF cream, Kezuo Yintong Cream, Benzoyl peroxide emulsifiable paste, Fusidic Acid Cream, Tretinoin emulsifiable paste, isotretinoin ointment, salicylic acid gel, tazarotene cream, The doctors trained in Western medicine such as adapalene gel often carry out external application for curing with externally applied drug, have the effect of certain, quick result, but doctor trained in Western medicine Zhi Biao is not Effect a permanent cure, easy recurrent exerbation.This disease of Chinese traditional treatment dispels inducement by nursing one's health in vivo, evident in efficacy, uneasy to recur, Small side effects, But the Chinese traditional treatment course for the treatment of is long, it is necessary to which long-term treatment can just see effect.But it is by oral method, oral drugs mostly The metabolism by stomach, liver, kidney is needed, internal organ are damaged with wound, it is unsuitable long-term use of.

The content of the invention

Ointment and its preparation in order to solve the above technical problem, the present invention provides a kind of effective adolescent acne Method.

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：30~50 parts of kuh-seng, 20~30 parts of azedarach, 20~30 parts of pomegranate root, Cortex Phellodendri 20~30 parts, 20~30 parts of peach root, 18~30 parts windproof, 18~30 parts of lotus leaf, 12~20 parts of alumen, 16~26 parts of the root of Dahurain angelica, 5~10 parts of 50~60 parts of camphor and whitish honey, the western medicine component is by 30~50 parts of vaseline and 30~50 parts of salicylic acid Composition.

Preferably, the ointment of the treatment adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component； The traditional Chinese medicinal components are made of the raw material of following parts by weight：35~45 parts of kuh-seng, 22~28 parts of azedarach, pomegranate root 23~26 Part, 22~26 parts of Cortex Phellodendri, 21~28 parts of peach root, 20~28 parts windproof, 20~26 parts of lotus leaf, 12~20 parts of alumen, the root of Dahurain angelica 20 5~10 parts of~24 parts, 50~60 parts of camphor and whitish honey, the western medicine component by 35-45 parts of vaseline and 35-45 part water Poplar acid composition.

Preferably, the ointment of the treatment adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component； The traditional Chinese medicinal components are made of the raw material of following parts by weight：38 parts of kuh-seng, 27 parts of azedarach, 25 parts of pomegranate root, 25 parts of Cortex Phellodendri, 6 parts of 25 parts of peach root, 24 parts windproof, 24 parts of lotus leaf, 17 parts of alumen, 21 parts of the root of Dahurain angelica, 53 parts of camphor and whitish honey, the Western medicine group Divide and be made of 38 parts of vaseline and 38 parts of salicylic acid.

Preferably, the ointment of the treatment adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component； The traditional Chinese medicinal components are made of the raw material of following parts by weight：43 parts of kuh-seng, 24 parts of azedarach, 24 parts of pomegranate root, 24 parts of Cortex Phellodendri, 8 parts of 23 parts of peach root, 26 parts windproof, 22 parts of lotus leaf, 15 parts of alumen, 23 parts of the root of Dahurain angelica, 56 parts of camphor and whitish honey, the Western medicine group Divide and be made of 43 parts of vaseline and 43 parts of salicylic acid.

The invention also discloses the preparation method of the ointment of above-mentioned treatment adolescent acne, include the following steps：

Step (1)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs kuh-seng, azedarach, pomegranate Root, Cortex Phellodendri, peach root, windproof, lotus leaf, the root of Dahurain angelica cleaning dry it is rear spare；

Step (2)：Medicinal material after step (1) cleaning is dried extracts respectively, respectively obtains shrubby sophora extract, azedarach carries Thing, pomegranate root extract, phellodendron extract, peach root extract, Radix Saposhnikoviae extract, Lotus Leafextract, Angelica Dahurica extract are taken, it is standby With：

Step (3)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs alumen, salicylic acid and white Alumen and salicylic acid, are first placed in container one and are uniformly mixed by honey, then again by whitish honey add container one in, with alumen and Salicylic acid is uniformly mixed, and obtains mixture one；

Step (4)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs vaseline, and kuh-seng is extracted Thing and phellodendron extract are added in container two, and vaseline is then added into container two is uniformly mixed, and obtains mixture two；

Step (5)：The container two for containing mixture two is heated to 45~80 DEG C, then by Cortex Meliae extract, pomegranate Root extract, peach root extract, Radix Saposhnikoviae extract, Lotus Leafextract, Angelica Dahurica extract are added in container two, after mixing Mixture three is obtained, mixture three is added into mixture one kind and is stirred evenly, that is, treatment adolescent acne of the present invention is made Ointment, be contained in tank and seal, be kept in dark place.Further, the preparation method of shrubby sophora extract use is：Will Kuh-seng is placed in marmite, and half an hour is soaked into marmite, and the weight ratio of kuh-seng and water is 1：3~5, immersion finishes, Marmite is heated to high heat to seethe with excitement, slow boiling of then converting boils a hour, silk filtering, and the dregs of a decoction add distilled water, same method again Immersion, decoct, filtering, filtrate will mix twice, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to shrubby sophora extract.

Further, the preparation method of Cortex Meliae extract use is：Azedarach is placed in marmite, and to marmite In soak half an hour, the weight ratio of azedarach and water is 1：3~5, immersion finishes, and marmite is heated to high heat to boil Rise, slow boiling of then converting boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, will twice Filtrate mixes, and heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to Cortex Meliae extract.

Further, the preparation method of pomegranate root extract use is：Pomegranate root is placed in marmite, and to marmite In soak half an hour, the weight ratio of pomegranate root and water is 1：3~5, immersion finishes, and marmite is heated to high heat to boil Rise, slow boiling of then converting boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, will twice Filtrate mixes, and heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to pomegranate root extract.

Further, the preparation method of phellodendron extract use is：Cortex Phellodendri is placed in marmite, and is added into marmite Water soaks half an hour, and the weight ratio of Cortex Phellodendri and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to phellodendron extract.

Further, the preparation method of peach root extract use is：Peach root is placed in marmite, and to marmite In soak half an hour, the weight ratio of peach root and water is 1：3~5, immersion finishes, and marmite is heated to high heat to boil Rise, slow boiling of then converting boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, will twice Filtrate mixes, and heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to peach root extract.

Further, the preparation method of Radix Saposhnikoviae extract use is：It is placed in windproof in marmite, and adds into marmite Water soaks half an hour, and the windproof and weight ratio of water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to Radix Saposhnikoviae extract.

Further, the preparation method of Lotus Leafextract use is：Lotus leaf is placed in marmite, and is added into marmite Water soaks half an hour, and the weight ratio of lotus leaf and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to Lotus Leafextract.

Further, the preparation method of Angelica Dahurica extract use is：The root of Dahurain angelica is placed in marmite, and is added into marmite Water soaks half an hour, and the weight ratio of the root of Dahurain angelica and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to Angelica Dahurica extract.

The pharmacological property of each taste Chinese medicine is as follows in the present invention：

Kuh-seng：Bitter；It is cold in nature.Return liver, kidney, large intestine, small intestinl channel, bladder, the heart channel of Hang-Shaoyin, bladder warp.Major function：Heat-clearing is dry It is wet；Wind dispelling insecticide.Main damp-heat dysentery；Hematochezia；Jaundice；Difficult urination；Oedema；Under band；Pruritus vulvae；Mange；Leprosy；Skin scabies Itch；Wet poison sore.1. pruritus vulvae under treatment zone.There is good therapeutic effect with lower color Huang, and male's swelling of vulva pruritus vulvae to women. 2nd, eczema mange is treated.Kuh-seng bath can remove damp-heat in lower-JIAO, and desinsection is antipruritic, has to pruitus caused by eczema mange Good mitigation.3. treat difficult urination.Kuh-seng bath can treat difficult urination caused by a variety of causes, scorching hot puckery pain.Especially Its difficult urination because of caused by gestation to women, cooperation take kuh-seng decoction effect more.

Pharmacological action：1. beautifying skin-protection function：It is cold in nature, there is the effect of heat-clearing and damp-drying drug, desinsection, kuh-seng bath can remove lower Jiao It is damp and hot, and desinsection is antipruritic, have good mitigation to pruitus, vegetable Chinese herbal medicine can Bergamot Mint Extract, dredging And pore is restrained, skin endotoxin contamination is removed, abundant herbal nutrition, promotes the growth of damaged blood vessels nerve cell and repair It is multiple, recover subcutaneous capillary cell viability, skin, which reappears, to compact fine and smooth, plays the role of beauty and skin care.2. antibacterial action：It is bitter Ginseng ether extract and alcohol extract have staphylococcus aureus stronger bacteriostasis；Kuh-seng flooding agent to trichophyton, with one heart Property trichophyta, Trichophyton schoenleini, Du small gemma tinea bacterium of big belly difficult to understand etc. have inhibitory action.3. antitumor action：Matrine is in vivo and in vitro There is inhibitory action to mouse ehrlich ascites cancer and sarcoma~180.4. leukogenic effect：Banlangen and oxymatrine have significantly Leukogenic effect, has obvious therapeutic effect to Neuroleptic Leukocytopenia caused by endoxan, X-ray and cobalt radiation exposure.5. anti-inflammatory Effect：Matrine is to mouse peritoneal exudation increase, rat carrageenan caused by auricle edema caused by mouse knoting oil, acetic acid Property footpad swelling, there is inhibitory action.6. arrhythmia acts on：Matrine can resist the cat room that chloroform~adrenaline induces Property fibrillation；Also resist the cavy room property fibrillation that the rat ventricular of Aconitine Induced and ouabain induce and institute is sucked to chloroform The rabbit arrhythmia cordis that the mouse ventricular fibrillation of cause, the rat ventricular of Aconitine Induced, chloroform~adrenaline induce has bright Aobvious antagonism；Kuh-seng total flavone can simultaneously resist Cardiac Myocytes are spontaneous and ouabain induces beating arhythmicity in addition, hardship Ginseng has obvious diuresis；Kuh-seng alkaloid still have it is stable, relieving asthma, immunosuppressive action.

Azedarach：Heat-clearing, eliminating dampness, desinsection.Pharmacological action：1) azedarach flooding agent tube dilution method, 1：40 pairs violet Trichophyta, microsporon audouini etc. have inhibitory action.2) in vitro test, 20% azedarach medicinal extract and 0.6% margosine are in 24h It is interior ascaris suum autogenic movement is disappeared, and have part roundworm death.3) in toosendanin saturated solution, ascaris suum can be made spontaneous Activity stopping, but effect appearance is slower, needs more than 4h, and it is seemingly paralysis effect to be not easy to recover after static.4) toosendanin is to meat poisoning poison Plain poisoning mice has therapeutic effect, with no matter oral 0.4,0.6LD50 is, intravenous, is subcutaneously injected and can make 1.7LD50 unit A types The survival of botulinum toxin intoxication mouse big portion, the LD50 of toosendanin are taken orally as 550mg/kg, are injected intravenously as 14.6mg/kg, subcutaneously Inject as 15.2mg/kg；Also there is rescued effect to botulinum toxin type B poisoning mice.

Pomegranate root：Bitterness, temperature.Desinsection, puckery intestines, stop-band.Control roundworm, tapeworm, chronic diarrhea, protracted dysentery, leukorrhea with reddish discharge.1) expelling parasite is made With：Granatenine is extremely strong to the killing effect of tapeworm, and 1:10000 hydrochloric acid granatenine can kill tapeworm in 5~10 minutes, but 1:It is counter to tapeworm when 50000 to have excitation.It is actually isopelletierine to prove such a active ingredient later.Pseudo- granatenine Anthelmintic action it is uncertain.Contain a large amount of tannins in fresh pomegranate, clinical observation proves that alkaloid is combined with tannin than not tying Conjunction person's anthelminthic effect is good, this is because tannin can make alkaloid become the indissoluble thus difficult compound absorbed, so as to abundant Ground plays a role enterozoon.Since granatum toxicity is larger, existing the sixth of the twelve Earthly Branches is replaced by more preferable medicine.2) antibacterial action：Body Outer experiment is to staphylococcus aureus, hemolytic streptococcus, comma bacillus, shigella dysenteriae, typhoid fever and paratyphosum Bacterium.Deformed rod Bacterium, Escherichia coli, Pseudomonas aeruginosa and tubercle bacillus have obvious inhibitory action.Also there is inhibitory action to a variety of pathomycetes.Its Antibacterial action may be related with wherein containing a large amount of tannins.3) antivirus action：Liquid is first injected into chick embryo allantoic cavity, half an hour Be inoculated with influenza virus (PR8 strain of influenza virus type A) afterwards or first virus inoculation inject medicine again, be incubated 48 it is small when after carry out hemagglutination again Experiment, it was demonstrated that granatum decoction is diluted to 1:10000~1:100000 still play the role of suppressing influenza virus.Its effect may also It is due to containing a large amount of tannins.

Cortex Phellodendri：It is bitter；It is cold.Channel tropism：Kidney channel；Bladder；Large intestine channel.Function：Heat-clearing and detoxifying drug；Heat-clearing and damp-drying drug.Cure mainly：It is damp and hot Dysentery, diarrhea, jaundice；Under nocturnal emission, stranguria with turbid discharge, band；Hectic fever due to yin labor heat, night sweat；And aphthae, red eye, swell pain, skin sore, skin Skin eczema.

Peach root：Peach root is the root of peach.There is the effect of clearing heat and promoting diuresis, promoting blood circulation and stopping pain.Hardship, puts down.Clearing heat and promoting diuresis, it is living Blood and relieving pain, preventing malaria, desinsection.For rheumathritis, pain in the back, traumatic injury, filariasis, tertian fever.

It is windproof：Acrid flavour, sweet, slightly warm in nature.Return bladder, lung, spleen, Liver Channel.Expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, stops convulsion.For diseases caused by external factors Exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw just, the insufficiency of the spleen with overabundance of dampness.

Lotus leaf：Lotus leaf clearing away summerheat, rises hair spleen sun, can the disease such as steady blood pressure, prevention hypertension, hyperlipidemia.Nuciferine There is clearing away the heart-fire, soothing the liver is fiery, rush down spleen fire, drop lung-fire and heat-clearing is reposed, conciliation endocrine, improvement microcirculation in human body. Lotus leaf nature and flavor are bitter, put down, Return liver, spleen, stomach, the heart channel of Hang-Shaoyin.There are clearing summer-heat and damp, sending up the lucid yang, cooling blood and hemostasis and other effects.But also have Antimitotic effect, there is stronger fungistatic effect.More drinks also have health-care effect.

Alumen：Dissolving phlegm, eliminating dampness, antidiarrheal, stops blooding, removing toxic substances, desinsection.Epilepsy, larynx numbness are controlled, remorse saliva is stopped up very, hepatitis, and jaundice is yellow It is swollen, taste-blindness rate, the prolapse of uterus, leukorrhea, rush down dysentery, bleeding from five sense organs or subcutaneous tissue, aphthae, sore hemorrhoid mange, water, fire, insect bite.

The root of Dahurain angelica：Chemical composition：Containing byak-angelicin, Byakangelicol, angelicotoxin etc..Major function:Wind-damp dispelling, promoting blood circulation row Purulence, myogenic pain relieving.For having a headache, having a toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus.The root of Dahurain angelica also has U.S. Hold effect, select the big and root of Dahurain angelica of the colour purity in vain without mould mark, take its root, grind for superfine end, be incorporated into the common skin care item of a bottle In, be sufficiently stirred with it is even, adhere to using, there is certain whitening effect.It is acrid in flavour and warm in nature, it is nontoxic.Wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic are stopped Bitterly.For having a headache, having a toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus.Drug action：1. wind-dispelling solution Table：For cold, the card such as headache, nasal obstruction, there are dispersing wind and cold, the effect for the pain that relieves the pain.Often and the compatibility such as the achene of Siberian cocklebur, the flower bud of lily magnolia.2. dispel Wind relieves pain：, can wind-expelling pain-stopping for intermittent headache pain, antimigraine, pain in the supra-orbital bone, nasosinusitis headache, tooth pain etc..3. dissipation apocenosis：With controlling Carbuncle swells sore, can apocenosis after bursting from the beginning of that can dissipate.4. eliminating dampness stops band：For women cold-dampness leukorrhea, energy eliminating dampness stops band, can match somebody with somebody sea The egg capsule of a mantis is equally used；Belong to humid tropics under, it is thick with lower Huang, heat-clearing and damp-drying drug such as Cortex Phellodendri can be matched somebody with somebody, CORTEX AILANTHI is equally used.5. declare clearing the nasal passage： Turbid tears for nasosinusitis grow stream, and loss of smell person, can match somebody with somebody the flower bud of lily magnolia, the achene of Siberian cocklebur is windproof, and Ligusticum wallichii is equally used.Drug effect：Root of Dahurain angelica master enters sun Bright, awakening consciousness, is apt to wind-expelling pain-stopping.Gums is controlled partially connects the swelling and pain of Face and cheek, toothache.Pharmacological action：Root of Dahurain angelica element can excited medulla oblongata Respiratory center, vasomotor center and vagus nerve, can make breathing enhancing, blood pressure rising, pulse slack-off.

Camphor：Camphor is the branch, dry, leaf and root of canella camphor tree, through crystalline particulate made from refinement.Camphor has Orifice opening, qi stagnation removing, ward off the effect of foul, desinsection is antipruritic, swelling and pain relieving, cures mainly the diseases such as mange itch, injuries from falls as well, toothache Shape.Main component is pure gum camphor (d~Camphora), is camphane class compound.Pungent, heat is nontoxic.Orifice opening, profit are stagnant Gas, controls middle evil perverse trend, cholera pain in the chest and abdomen, cold-dampness athlete's foot, mange wind scabies, carious tooth, and desinsection wards off moth.In footwear, go athlete's foot (when It is precious).Camphor, which is applied to skin, gentle stimulation and antisepsis.

Whitish honey：Refer to acacia nectar, its property of acacia honey is refrigerant, has the effect of diuresis of drying, cooling blood and hemostasis of sophora flower, energy The normal resistivity of capillary is kept, has vasodilator, improves blood circulation, prevent vascular sclerosis, reduce blood fat and blood pressure Deng effect, and for pre- anti-stroke, while also there is the effect of heat-clearing bowl spares, detoxify and moisturize；Also contain acaciin and volatilization in honey Oil, can antibacterial, anti-corrosion and cough-relieving；Clearing heat and detoxicating, anti-wrinkle ecchymose removing, beauty treatment healthy tendency, the strongly fragrant dredging collateral of solution.

Vaseline：Vaseline is a kind of mineral wax, it will not be absorbed by the skin, and can form a pipe protection in skin surface Film, makes the moisture of skin be not easy to evaporate lost, and it is largely insoluble in water, can adhere on the skin for a long time, therefore with fine Moistening effect, be very suitable for dry skin use.It can be used to as lip-stick, hand lotion, wipe face or body of rubbing one's body with a towel, be very good Moisturizing articles for use.Also there is the effect for removing scar.Vaseline is nonirritant, stable to be unlikely to deteriorate, and is not easy to cause human body quick Sense, is most suitable for spices, the people of alcohol intolerance added to general moisturising product.

Salicylic acid, is plant extract of willow bark, is a kind of natural antiphlogistic.Salicylic acid is usually used in treating in dept. of dermatology Various chronic dermatosis such as acne (whelk), tinea etc..Salicylic acid can dispel cutin, sterilization, anti-inflammatory, thus be very suitable for treating Whelk caused by clogging of pores, international mainstream product for resolving poxes are all salicylated, and concentration is typically 0.5~2%.Yi Mei Lay, the acne control conditioning liquid of Marykay are all salicylated product for resolving poxes.

" organic conception " is had been accepted as at present, " diagnosis and treatment based on an overall analysis of the illness and the patient's condition ", " compound use ", " compound compatibility medication is such as used military forces " are the traditional Chinese medical science Most scientific most effective several big advantages, wherein " compound compatibility medication is such as used military forces " is the original theory of traditional Chinese medicine of very science.In The tight compatibility that each medicine is all linked with one another as arraying troops for battle in prescription is cured, is that it is better than the effective means of western medicine formula.The traditional Chinese medical science Prescription theory thinks that each prescription, not only needs to select the suitable appropriate compatibility of medicine according to etiology and pathogenesis, while should also accord with Close the prescription compatibility theory of the basic structure of prescription, i.e. " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make ", just It is that it establishes the scientific matching on the comprehensive judgement basis to the disease interpretation of the cause, onset and process of an illness.Middle medical square is whole by too many levels, Mutiple Targets The biological mechanism adjusted is closed, therapeutic effect more more longlasting than Western medicine, that more green natural has no toxic side effect can be obtained, and it is this Curative effect is built upon on the original theoretical accurate instruction of above-mentioned traditional Chinese medical science tradition, and the present invention just have followed this principle.

Monarch drug in a prescription treats primary symptom in the side of referring to, plays the medicine of primary treatment, can use as required simply or a few taste medicines.Minister Medicine is the medicine assisted main ingredient or strengthen main ingredient effect.Adjutant is the medicine for the toxicity assisted main ingredient treatment and disease or suppress main ingredient Thing.It is that each medicine of guiding goes directly diseased region or the effect of each medicine of reconciling to make medicine.

The present invention is using the antipruritic kuh-seng of wind dispelling insecticide as monarch drug in a prescription, to aid in the clearing heat and detoxicating azedarach of desinsection purging intense heat, pomegranate Root, Cortex Phellodendri, peach root are ministerial drug, to relieve pain wind-dispelling, desinsection stop the windproof of scabies, alumen, camphor, the root of Dahurain angelica as adjutant, to suppress thin Vaseline, salicylic acid, lotus leaf, the whitish honey of bacterium growth are to make medicine.Desinsection stops scabies, anti-acne U.S. face.The ointment of the present invention through facing for a long time Bed is put into practice configuration and is formed, and is suited the remedy to the case according to the cause of disease, has clearing heat-fire, detoxicating and resolving a mass, healing up sore and subduing swelling, cooling blood and dissolving stasis, blood-nourishing The effect of wind-dispelling, moist skin, hot gas in skin is removed, dissipates malignant sore, skin of moistening, dissipation skin chronic inflammation, excludes poison in vivo Element, then with the use of Western medicine vaseline rapid osmotic, treat both principal and secondary aspect of disease, comprehensively solve adolescent acne and acne scars are to skin Infringement problem, good absorption effect is evident in efficacy, has no toxic side effect and clinical adverse, uneasy to recur, according to clinical verification to green grass or young crops Phase in spring acne cure rate is higher.

Embodiment

The present invention is further described with reference to embodiment.

Embodiment 1

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：30 parts of kuh-seng, 30 parts of azedarach, 20 parts of pomegranate root, 30 parts of Cortex Phellodendri, peach root 20 Part, 30 parts windproof, 18 parts of lotus leaf, 20 parts of alumen, 16 parts of the root of Dahurain angelica, 60 parts of camphor and 5 parts of whitish honey, the western medicine component is by 30 parts Vaseline and 50 parts salicylic acid composition.

Embodiment 2

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：50 parts of kuh-seng, 20 parts of azedarach, 30 parts of pomegranate root, 20 parts of Cortex Phellodendri, peach root 30 Part, 18 parts windproof, 30 parts of lotus leaf, 12 parts of alumen, 26 parts of the root of Dahurain angelica, 50 parts of camphor and 10 parts of whitish honey, the western medicine component is by 50 The vaseline of part and 30 parts of salicylic acid composition.

Embodiment 3

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：35 parts of kuh-seng, 28 parts of azedarach, 23 parts of pomegranate root, 26 parts of Cortex Phellodendri, peach root 21 Part, 28 parts windproof, 20 parts of lotus leaf, 20 parts of alumen, 20 parts of the root of Dahurain angelica, 60 parts of camphor and 5 parts of whitish honey, the western medicine component is by 35 parts Vaseline and 45 parts salicylic acid composition.

Embodiment 4

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：45 parts of kuh-seng, 22 parts of azedarach, 26 parts of pomegranate root, 22 parts of Cortex Phellodendri, peach root 28 Part, 20 parts windproof, 26 parts of lotus leaf, 12 parts of alumen, 24 parts of the root of Dahurain angelica, 50 parts of camphor and 10 parts of whitish honey, the western medicine component is by 45 The vaseline of part and 35 parts of salicylic acid composition.

Embodiment 5

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：38 parts of kuh-seng, 27 parts of azedarach, 25 parts of pomegranate root, 25 parts of Cortex Phellodendri, peach root 25 Part, 24 parts windproof, 24 parts of lotus leaf, 17 parts of alumen, 21 parts of the root of Dahurain angelica, 53 parts of camphor and 6 parts of whitish honey, the western medicine component is by 38 parts Vaseline and 38 parts salicylic acid composition.

Embodiment 6

A kind of ointment for treating adolescent acne, the paste are mixed by traditional Chinese medicinal components and western medicine component；In described Medicine component is made of the raw material of following parts by weight：43 parts of kuh-seng, 24 parts of azedarach, 24 parts of pomegranate root, 24 parts of Cortex Phellodendri, peach root 23 Part, 26 parts windproof, 22 parts of lotus leaf, 15 parts of alumen, 23 parts of the root of Dahurain angelica, 56 parts of camphor and 8 parts of whitish honey, the western medicine component is by 43 parts Vaseline and 43 parts salicylic acid composition.

The invention also discloses the preparation method of the ointment of above-mentioned treatment adolescent acne, include the following steps：

Step (1)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs kuh-seng, azedarach, pomegranate Root, Cortex Phellodendri, peach root, windproof, lotus leaf, the root of Dahurain angelica cleaning dry it is rear spare；

Step (2)：Medicinal material after step (1) cleaning is dried extracts respectively, respectively obtains shrubby sophora extract, azedarach carries Thing, pomegranate root extract, phellodendron extract, peach root extract, Radix Saposhnikoviae extract, Lotus Leafextract, Angelica Dahurica extract are taken, it is standby With：

Step (3)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs alumen, salicylic acid and white Alumen and salicylic acid, are first placed in container one and are uniformly mixed by honey, then again by whitish honey add container one in, with alumen and Salicylic acid is uniformly mixed, and obtains mixture one；

Step (4)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs vaseline, and kuh-seng is extracted Thing and phellodendron extract are added in container two, and vaseline is then added into container two is uniformly mixed, and obtains mixture two；

Step (5)：The container two for containing mixture two is heated to 45~80 DEG C, then by Cortex Meliae extract, pomegranate Root extract, peach root extract, Radix Saposhnikoviae extract, Lotus Leafextract, Angelica Dahurica extract are added in container two, after mixing Mixture three is obtained, mixture three is added into mixture one kind and is stirred evenly, that is, treatment adolescent acne of the present invention is made Ointment, be contained in tank and seal, be kept in dark place.

The preparation method that the shrubby sophora extract uses is：Kuh-seng is placed in marmite, and is soaked into marmite The weight ratio of half an hour, kuh-seng and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then conversion text Fire boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice, heating It is concentrated into liquid medicine to boil dry, remaining substrate is air-dried up to shrubby sophora extract.

The preparation method that the Cortex Meliae extract uses is：Azedarach is placed in marmite, and adds water into marmite Soak half an hour, the weight ratio of azedarach and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to Cortex Meliae extract.

The preparation method that the pomegranate root extract uses is：Pomegranate root is placed in marmite, and adds water into marmite Soak half an hour, the weight ratio of pomegranate root and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to pomegranate root extract.

The preparation method that the phellodendron extract uses is：Cortex Phellodendri is placed in marmite, and is soaked into marmite The weight ratio of half an hour, Cortex Phellodendri and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then conversion text Fire boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice, heating It is concentrated into liquid medicine to boil dry, remaining substrate is air-dried up to phellodendron extract.

The preparation method that the peach root extract uses is：Peach root is placed in marmite, and adds water into marmite Soak half an hour, the weight ratio of peach root and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then Conversion slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice Close, heating is concentrated into liquid medicine and boils dry, and remaining substrate is air-dried up to peach root extract.

The preparation method that the Radix Saposhnikoviae extract uses is：It is placed in windproof in marmite, and is soaked into marmite Half an hour, the windproof and weight ratio of water are 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then conversion text Fire boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice, heating It is concentrated into liquid medicine to boil dry, remaining substrate is air-dried up to Radix Saposhnikoviae extract.

The preparation method that the Lotus Leafextract uses is：Lotus leaf is placed in marmite, and is soaked into marmite The weight ratio of half an hour, lotus leaf and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then conversion text Fire boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice, heating It is concentrated into liquid medicine to boil dry, remaining substrate is air-dried up to Lotus Leafextract.

The preparation method that the Angelica Dahurica extract uses is：The root of Dahurain angelica is placed in marmite, and is soaked into marmite The weight ratio of half an hour, the root of Dahurain angelica and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, then conversion text Fire boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix twice, heating It is concentrated into liquid medicine to boil dry, remaining substrate is air-dried up to Angelica Dahurica extract.

The application method of the ointment of above-mentioned treatment adolescence acne is：After with warm water, face is cleaned up, by medicine Cream is applied to disease sites, twice a day, smears sooner or later.

Case is tested：

Choose 90 adolescence patients with acne；

90 patient's mean randoms are divided into three groups, ointment made of first group of prescription using the embodiment of the present invention 5, and second Group uses salicylic acid latex, and the 3rd group uses Kezuo Yintong Cream, and three groups of clinical datas are statistically analyzed, no significant difference Meaning (p>0.05), it is comparable.

Criterion of therapeutical effect and result

(1) criterion of therapeutical effect

According to《New Chinese medicine guideline of clinical investigations》Carry out efficacy evaluation.

1. cure：Adolescent acne disappears, and leaves behind a small amount of acne print, does not recur；

It is 2. effective：Adolescent acne disappears, but recurs after a period of time；

It is 3. invalid：Scar has no significant change.

(2) result

In first group 30,25 are cured, recurrence 4 again after healing；

In second group 30,20 are cured, 18 are recurred after healing.

3rd group, in 30,15 are cured, 14 are recurred after healing.

Three groups of cure rates, total effective rates relatively there were significant differences (P<0.05), test group is substantially better than control group.This hair The ointment of the acne of the bright treatment adolescence it is most prominent the advantages of be, non-relapse after healing, and bigcatkin willow yogurt Glue and Kezuo Yintong Cream also have acne obvious therapeutic effect using rear, but are discontinued after a period of time, and recurrence rate is higher, The advantages of present invention is most prominent is, controls that recurrence rate after healing is relatively low, and four recurred again are after second is cured, wherein three Example no longer recurs, and only one belongs to refractory acne, is reoccurred once again after half a year, also not multiple so far after treating again Hair.

The effect of for clearer explanation ointment of the present invention, provide following model case.

Case 1, Zhang, man, 18 years old, student Anyang human face's acne, when coming here, face 1/3 has acne, and And it is red and swollen around acne, there is liquid exudation, Zhang detests very much for " whelk " of oneself, readme：It is used for very much Kind ointment, but recur always, also take a period of time herbal treatment and also had no obvious effect, sensation is felt oneself inferior very much, classmates Also often inquire when the small pox of oneself can disappear, it is very painful, ointment made of the formula of the embodiment of the present invention 5 is given, Enjoin him sooner or later with being used after warm water face cleaning, after medication three days, acne is red and swollen to dissipate, and medication 5 days, acne disappears, and leaves behind acne Print, recurrence that so far there are no.

Case 2, Lee, man, 35 years old, Hebi City people, the facial acne since 20 years old, till now, acne is controlled Treat repeatedly, be all after healing, spend some months and recur again, come here interrogation, readme upon somebody's introduction, oneself baby dislikes and avoids oneself Small pox, give ointment prepared by the formula of the embodiment of the present invention 5, used after enjoining its morning and evening warm water face cleaning, after medication three days, Small pox disappears, and leaves behind acne print, and since its acne time is grown, recurrence once, is continuing with the ointment again after six months, cures Afterwards, recurrence that so far there are no, pays a return visit, acne print on the face substantially can't see for the previous period.

Case 3, Mr. Wang, female, 26 years old, after face acnes come here, made of the formula of giving the embodiment of the present invention 5 Ointment, acne sites are applied to after enjoining its morning and evening face cleaning, and after three days, small pox disappears, recurrence that so far there are no.

The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or use the present invention. A variety of modifications to these embodiments will be apparent for those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, it is of the invention The embodiments shown herein is not intended to be limited to, but more to be met and the principles and novel features disclosed herein phase Consistent most wide scope.

Claims (6)

1. a kind of ointment for treating adolescent acne, it is characterised in that the paste is mixed by traditional Chinese medicinal components and western medicine component； The traditional Chinese medicinal components are made of the raw material of following parts by weight：30~50 parts of kuh-seng, 20~30 parts of azedarach, pomegranate root 20~30 Part, 20~30 parts of Cortex Phellodendri, 20~30 parts of peach root, 18~30 parts windproof, 18~30 parts of lotus leaf, 12~20 parts of alumen, the root of Dahurain angelica 16 5~10 parts of~26 parts, 50~60 parts of camphor and whitish honey, the western medicine component is by 30~50 parts of vaseline and 30~50 parts Salicylic acid forms.

2. the ointment for the treatment of adolescent acne according to claim 1, it is characterised in that the paste is by traditional Chinese medicinal components and west Medicine component mixes；The traditional Chinese medicinal components are made of the raw material of following parts by weight：35~45 parts of kuh-seng, azedarach 22~28 Part, 23~26 parts of pomegranate root, 22~26 parts of Cortex Phellodendri, 21~28 parts of peach root, 20~28 parts windproof, 20~26 parts of lotus leaf, alumen 5~10 parts of 12~20 parts, 20~24 parts of the root of Dahurain angelica, 50~60 parts of camphor and whitish honey, the western medicine component are all by 35~45 parts Intellectual circle and 35~45 parts of salicylic acid composition.

3. the ointment for the treatment of adolescent acne according to claim 2, it is characterised in that the paste is by traditional Chinese medicinal components and west Medicine component mixes；The traditional Chinese medicinal components are made of the raw material of following parts by weight：38 parts of kuh-seng, 27 parts of azedarach, pomegranate 25 parts of root, 25 parts of Cortex Phellodendri, 25 parts of peach root, 24 parts windproof, 24 parts of lotus leaf, 17 parts of alumen, 21 parts of the root of Dahurain angelica, 53 parts of camphor and whitish honey 6 parts, the western medicine component is made of 38 parts of vaseline and 38 parts of salicylic acid.

4. the ointment for the treatment of adolescent acne according to claim 2, it is characterised in that the paste is by traditional Chinese medicinal components and west Medicine component mixes；The traditional Chinese medicinal components are made of the raw material of following parts by weight：43 parts of kuh-seng, 24 parts of azedarach, pomegranate 24 parts of root, 24 parts of Cortex Phellodendri, 23 parts of peach root, 26 parts windproof, 22 parts of lotus leaf, 15 parts of alumen, 23 parts of the root of Dahurain angelica, 56 parts of camphor and whitish honey 8 parts, the western medicine component is made of 43 parts of vaseline and 43 parts of salicylic acid.

5. the preparation method of the ointment of the treatment adolescent acne according to Claims 1 to 4 any one, its feature exist In including the following steps：

Step (1)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs kuh-seng, azedarach, pomegranate root, Huang Cypress, peach root, windproof, lotus leaf, the root of Dahurain angelica cleaning dry it is rear spare；

Step (2)：Medicinal material after step (1) cleaning is dried extracts respectively, respectively obtains shrubby sophora extract, azedarach extraction Thing, pomegranate root extract, phellodendron extract, peach root extract, Radix Saposhnikoviae extract, Lotus Leafextract, Angelica Dahurica extract, it is standby With：

Step (3)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs alumen, salicylic acid and whitish honey, first Alumen and salicylic acid are placed in container one and are uniformly mixed, is then again added whitish honey in container one, with alumen and bigcatkin willow Acid is uniformly mixed, and obtains mixture one；

Step (4)：Raw material proportioning according to the ointment of the treatment adolescent acne weighs vaseline, by shrubby sophora extract and Phellodendron extract is added in container two, and vaseline is then added into container two is uniformly mixed, and obtains mixture two；

Step (5)：The container two for containing mixture two is heated to 45~80 DEG C, then carries Cortex Meliae extract, pomegranate root Take thing, peach root extract, Radix Saposhnikoviae extract, Lotus Leafextract, Angelica Dahurica extract to add in container two, must mix after mixing Compound three, adds mixture one kind by mixture three and stirs evenly, that is, the medicine for the treatment of adolescent acne of the present invention is made Cream, is contained in tank and seals, is kept in dark place.

6. the preparation method of the ointment for the treatment of adolescent acne according to claim 5, it is characterised in that the kuh-seng Extract use preparation method be：Kuh-seng is placed in marmite, and half an hour is soaked into marmite, kuh-seng and water Weight ratio is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, and slow boiling of then converting boils a hour, silk Filtering, the dregs of a decoction add distilled water again, with method immersion, decoct, filtering, filtrate will mix twice, heating is concentrated into liquid medicine and boils dry, remaining Substrate is air-dried up to shrubby sophora extract；

The preparation method that the Cortex Meliae extract uses is：Azedarach is placed in marmite, and is soaked into marmite The weight ratio of half an hour, azedarach and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, is then converted Slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix, and add twice Thermal concentration to liquid medicine boils dry, and remaining substrate is air-dried up to Cortex Meliae extract；

The preparation method that the pomegranate root extract uses is：Pomegranate root is placed in marmite, and is soaked into marmite The weight ratio of half an hour, pomegranate root and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, is then converted Slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix, and add twice Thermal concentration to liquid medicine boils dry, and remaining substrate is air-dried up to pomegranate root extract；

The preparation method that the phellodendron extract uses is：Cortex Phellodendri is placed in marmite, and is soaked into marmite half Hour, the weight ratio of Cortex Phellodendri and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, and slow boiling of then converting is endured Make a hour, silk filtering, the dregs of a decoction add distilled water again, with method immersion, decoct, filtering, filtrate will mix twice, heating concentration Boiled dry to liquid medicine, remaining substrate is air-dried up to phellodendron extract；

The preparation method that the peach root extract uses is：Peach root is placed in marmite, and is soaked into marmite The weight ratio of half an hour, peach root and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, is then converted Slow boiling boils a hour, silk filtering, and the dregs of a decoction add distilled water again, with method immersion, decocts, filtering, filtrate will mix, and add twice Thermal concentration to liquid medicine boils dry, and remaining substrate is air-dried up to peach root extract；

The preparation method that the Radix Saposhnikoviae extract uses is：It is placed in marmite, and is soaked into marmite half by windproof Hour, the windproof and weight ratio of water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, and slow boiling of then converting is endured Make a hour, silk filtering, the dregs of a decoction add distilled water again, with method immersion, decoct, filtering, filtrate will mix twice, heating concentration Boiled dry to liquid medicine, remaining substrate is air-dried up to Radix Saposhnikoviae extract；

The preparation method that the Lotus Leafextract uses is：Lotus leaf is placed in marmite, and is soaked into marmite half Hour, the weight ratio of lotus leaf and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, and slow boiling of then converting is endured Make a hour, silk filtering, the dregs of a decoction add distilled water again, with method immersion, decoct, filtering, filtrate will mix twice, heating concentration Boiled dry to liquid medicine, remaining substrate is air-dried up to Lotus Leafextract；

The preparation method that the Angelica Dahurica extract uses is：The root of Dahurain angelica is placed in marmite, and is soaked into marmite half Hour, the weight ratio of the root of Dahurain angelica and water is 1：3~5, immersion finishes, and marmite is heated to high heat to seethe with excitement, and slow boiling of then converting is endured Make a hour, silk filtering, the dregs of a decoction add distilled water again, with method immersion, decoct, filtering, filtrate will mix twice, heating concentration Boiled dry to liquid medicine, remaining substrate is air-dried up to Angelica Dahurica extract.