CN110090285A - A kind of plaster and preparation method thereof for treating sciatica - Google Patents
A kind of plaster and preparation method thereof for treating sciatica Download PDFInfo
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- CN110090285A CN110090285A CN201910432842.7A CN201910432842A CN110090285A CN 110090285 A CN110090285 A CN 110090285A CN 201910432842 A CN201910432842 A CN 201910432842A CN 110090285 A CN110090285 A CN 110090285A
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Abstract
The invention discloses a kind of plaster compositions for treating sciatica, by weight, it prepares raw material to include at least: 20~40 parts of spina gleditsiae, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of radix aconiti lateralis preparata, 1~10 part of cortex cinnamomi, 10~20 parts of turmeric, 10~20 parts of rhizoma atractylodis, 20~40 parts of semen coicis, 5~15 parts of the root of fangji, 130~170 parts of Tourmaline;The present invention has good therapeutic effect for the sciatica as caused by a variety of causes, and onset time is short, can mitigate patient's slight illness in time.
Description
Technical field
The present invention relates to tcm field more particularly to a kind of plaster and preparation method thereof for treating sciatica.
Background technique
Sciatica is a syndrome, refers to that the pain in sciatic nerve access and its distributed area, range contain
Outside and foot, pain can seriously affect the work and life of patient, the especially disease of sharp ache after human thigh rear portion, shank
People even is difficult to walk, and body changes, such as waist buckling, bending knee, tiptoe land.The reason of causing sciatica has
It is a variety of, minority be primary ischiatitises, majority be it is secondary, i.e. the lesion of sciatic nerve part and surrounding structure is to seat
Bone nerve causes stimulation compressing and damage, and most commonly seen is the sciatica as caused by protrusion of lumber intervertebral disc, other reasons
Lumbar vertebrae osteoarthrosis, sacro-iliitis etc. can be enumerated.
Sciatica is classified as " rheumatism " scope in Chinese medicine, the cause of disease is mostly by attacking channels and collaterals outside wind-cold damp pathogen, and QI-blood circulation is not
Caused by smooth, but a difference is had for different sufferer situations, when this disease of tcm syndrome differentiation and treatment, and sciatica is subdivided into cold
Wet solidifying network, it is damp and hot invade four seed type such as network, obstruction of collaterals by blood stasis, kidney deficiency and liver, and be difficult in existing technology these four situations is complete
Cover entirely, realizes the effect of a Fang Duozhi.In addition, the underlying problem of secondary sciatica is varied, some are silk floss
A kind of chronic sympton prolonged, it is difficult to eradicate, sufferer endures slight illness for a long time, it is also very desirable to therapeutic scheme quick, effect is good.
Summary of the invention
In order to solve the above-mentioned technical problem, the first aspect of the present invention provides a kind of plaster group for treating sciatica
Close object prepare raw material by weight and include at least: 20~40 parts of spina gleditsiae, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of radix aconiti lateralis preparata,
1~10 part of cortex cinnamomi, 10~20 parts of turmeric, 10~20 parts of rhizoma atractylodis, 20~40 parts of semen coicis, 5~15 parts of the root of fangji, Tourmaline 130~
170 parts.
It is as a kind of perferred technical scheme, by weight, described that prepare raw material also include 50~70 parts of radix rehmanniae preparata, Chinese ephedra
20~40 parts, 20~40 parts of asarum.
It is as a kind of perferred technical scheme, by weight, described that prepare raw material also include 50~70 parts of radix rehmanniae preparata, Chinese ephedra
20~40 parts, 20~40 parts of asarum, 40~60 parts of Bi Bo, 50~70 parts of Hua Chuan.
The second aspect of the present invention provides a kind of plaster for treating sciatica, prepares raw material including at least above-mentioned
Plaster composition;The raw material for preparing also includes plaster substrate, and by weight, the raw material for preparing of plaster substrate at least wraps
Contain: 270~330 parts of lanolin, 0.01~0.1 part of azone, 0.01~0.3 part of borneol, 0.01~0.2 part of menthol, camphor
0.01~0.1 part.
As a preferred embodiment, the sum of the menthol and the weight of camphor account for lanolin weight 0.03~
0.1wt%.
As a preferred embodiment, the weight for preparing spina gleditsiae in raw material, rhizoma atractylodis, lanolin, Tourmaline
Than for (1~3): 1:(18~22): (8~12).
As a preferred embodiment, by weight, the raw material for preparing of the plaster substrate also includes: aloes powder
0.1~1 part, 0.1~1 part of Moschus powder.
As a preferred embodiment, the weight ratio of the aloes powder and Moschus powder is 1:1.
As a preferred embodiment, the sum of the aloes powder and the weight of Moschus powder account for the 0.2 of lanolin weight
~0.5wt%.
The third aspect of the present invention provides a kind of preparation method of the plaster of above-mentioned treatment sciatica, including with
Lower step: plaster composition being mixed and beats powder, and powder diameter is 200 mesh, then powder is mixed with plaster substrate and is tuned into paste, most
Ointment is applied on no mycelia cloth afterwards.
The utility model has the advantages that a kind of plaster for treating sciatica provided by the invention is for the ischium as caused by a variety of causes
Neuralgia has good therapeutic effect, and onset time is short, can mitigate patient's slight illness in time;In addition, the plaster cures mainly seat
Osteoneuralgia can also generate therapeutic effect, such as neck, thoracolumbar vertebrae, joint to the ailing of other positions, for gynecological disease, such as
Dysmenorrhea, pelvic inflammatory disease are equally effective.
Specific embodiment
In conjunction with preferred implementation method of the invention below detailed description and including embodiment can be further understood that this hair
Bright content.Unless otherwise indicated, all technologies used herein and scientific term all have general with the application fields
Logical technical staff's is generally understood identical meaning.If mentioned in the definition and the application of the concrete term disclosed in the prior art
Any definition supplied is inconsistent, then term provided herein of being subject to defines.
It is used in the present context, unless being clearly dictated in context, otherwise without the spy of the single plural form of restriction
Sign is also intended to the feature including plural form.It will also be appreciated that term as used herein " by ... preparation " it is synonymous with "comprising",
" comprising ", " including ", " having ", "comprising" and/or " including " indicate stated group when used in this manual
Object, step, method, product or device are closed, but does not preclude the presence or addition of one or more of the other composition, step, method, system
Product or device.In addition, using " preferred ", " preferably ", " preferred " etc. to be when describing presently filed embodiment
Refer to, can provide the embodiment of the present invention of certain beneficial effects in some cases.However, under identical circumstances or other feelings
Under condition, other embodiments are also likely to be preferred.In addition to this, not dark to the statement of one or more preferred embodiments
Show that other embodiments are unavailable, is also not intended to exclude other embodiments except the scope of the present invention.
In order to solve the above-mentioned technical problem, the first aspect of the present invention provides a kind of plaster group for treating sciatica
Close object prepare raw material by weight and include at least: 20~40 parts of spina gleditsiae, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of radix aconiti lateralis preparata,
1~10 part of cortex cinnamomi, 10~20 parts of turmeric, 10~20 parts of rhizoma atractylodis, 20~40 parts of semen coicis, 5~15 parts of the root of fangji, Tourmaline 130~
170 parts.
In some preferred embodiments, by weight, it prepares raw material to include at least: 30 parts of spina gleditsiae, Radix Angelicae Pubescentis 9
Part, 9 parts of radix aconiti lateralis preparata, 6 parts of cortex cinnamomi, 16 parts of turmeric, 15 parts of rhizoma atractylodis, 30 parts of semen coicis, 9 parts of the root of fangji, 150 parts of Tourmaline.
Spina gleditsiae
Spina gleditsiae, warm-natured, acrid flavour, return liver warp, stomach meridian have the effect of detumescence and poison retention, apocenosis desinsection, contain flavones
The ingredients such as glycosides, phenols, amino acid, Quercetin, fisetin, young fustic, leucocyanidin, palmitinic acid, to Staphylococcus aureus
Bacterium and micrococcus catarrhalis have inhibiting effect.
Radix Angelicae Pubescentis
Radix Angelicae Pubescentis, slightly warm in nature, acrid flavour, hardship return kidney channel, bladder meridian, have the effect of dispelling wind and eliminating dampness, arthritis analgesic, contain
Bergapten, Thymol etc. also contain columbianetin, o-acetylcolumbianetin, angelic acid, crotonic acid, Osthole, dihydro
Europe oroselol, angelate, osthole, Angelica pubescens alcohol, angelol D, columbianetin, different imperatorin, dihydro mountain
The ingredients such as celery alcohol-β-D-Glucose glycosides, bergaptol, nerolidol.Animal experiments show that the alcohol extract of Radix Angelicae Pubescentis has antiplatelet solidifying
Collection and anti thrombotic action, water decoction or liquid extract have calmness, hypnosis, analgesia, anti-inflammatory effect to rat, in addition there are decompression, resist
Arrhythmia cordis, antitumor, antibacterial promote the effects of lipolysis, excited breathing.
Radix aconiti lateralis preparata
Radix aconiti lateralis preparata, extremely hot in nature, acrid flavour, sweet, thoughts of returning home warp, kidney channel, the spleen channel have recuperating depleted yang, and mends fire supporing yang is wet by chill
The effect of evil, the diterpene dibasic acid esters Alkaloid containing severe toxicity in unprocessed Radix Aconiti Lateralis, such as aconitine, Hypaconitine, mesaconine, tower draw younger brother
Amine, chuan-wu base A, chuan-wu base B (also known as Ka meter Cha Lin), also toxic weaker atisine, amino phenols, demethyl coclaurine etc. at
Point, small part noxious material outflows with water after processing, and is largely converted into the diterpene monoesters Alkaloid that toxicity substantially reduces.
Radix aconiti lateralis preparata can with heart tonifying, resist myocardial ischemia, Hemorrhagic shock, inhibit coagulation function and antithrombus formation, also there is anti-inflammatory, analgesia, office
Portion's anesthesia, the effect of enhancing humoral immunity.
The concocting method of the unprocessed Radix Aconiti Lateralis can for it is well known to those skilled in the art any one.
Cortex cinnamomi
Cortex cinnamomi, extremely hot in nature is acrid flavour, sweet, returns kidney channel, the spleen channel, the heart channel of Hang-Shaoyin, Liver Channel, has mends fire supporing yang, guiding fire to origin, cold dispelling
Analgesic, the effect of warming meridian, 1.98%-2.06% containing volatile oil, main component is cinnaldehydrum, there are also acetic acid cassia bark ester,
Ergol, trans isomer cinnamic acid, natrium cinnamicum, cassia bark glycosides, cinnamyl alcohol, cortex cinnamomi alcohol acetate, Ingredients Such As Coumarin.Pharmacology is ground
Study carefully the stimulation for showing that cortex cinnamomi has mitigation to stomach, and gastrointestinal smooth muscle spasmus can be released, there is very strong antiulcer to make
With;Can antagonism platelet aggregation, have the function of improve cardiovascular system, adjust body's immunity;Central nervous system,
Have the effects that calmness, eases pain, is antipyretic, anticonvulsion;There are prevention and protective effect to the deficiency of yang, yin-deficient model;Resist with certain
Inflammation effect;With very strong fungicidal action;In addition, there are also antitumor functions.
Turmeric
Turmeric, warm-natured, bitter, pungent, converge to the spleen channel, Liver Channel have the effect of breaking blood and promoting the circulation of qi, inducing meastruation to relieve menalgia, activating microcirculation and removing stasis medicinal,
Mainly contain volatile oil and phenolic substance, volatile oil has identified 51 kinds of ingredients, based on terpenoid, mainly have turmerone,
Zingerene etc., phenolic constituent mainly have curcumin etc., separately containing the new ketone of turmeric, 3- sitosterol, 3- sitosterol -3-O- daucosterol,
Turmeric polysaccharide etc..Pharmacological research shows that turmeric has liver protection, cholagogue, antibacterial, anti-inflammatory, antitumor, anti-AIDS, antifertility, drop blood
Rouge, resisting pathogenic microbes and disease-resistant protozoon accelerate the effects of wound healing, anti-mutation;There is protective effect to digestive system;Increase
Heart coronary artery blood flow;Anticoagulation and inhibition platelet aggregation.
Rhizoma atractylodis
Rhizoma atractylodis, warm-natured, acrid flavour, hardship, converge to the spleen channel, stomach meridian, Liver Channel have the effect of drying damp and strengthening spleen, expelling wind and clearing away cold, main
Ingredient is atractylol, atractylone, hinesol and eucalyptol etc..Pharmacological research shows rhizoma atractylodis to tubercle bacillus, Staphylococcus aureus
Bacterium, large intestine, withered grass and Pseudomonas aeruginosa have significant sterilization effect
Semen coicis
Semen coicis, cool in nature, sweet in flavor, converge to the spleen channel, stomach meridian, lung channel have invigorating the spleen excreting dampness, remove numbness antidiarrheal, the function of clearing away heat and eliminating pus
Effect, chemical component is containing Coixol, Coixenolide, triterpenoid, sterol ester, linoleic acid, palmitinic acid, stearic acid etc., semen coicis
Pharmacological action have it is antitumor, improve immunity, be hypoglycemic, drop blood calcium, blood pressure lowering, inhibiting trypsase etc..
The root of fangji
The root of fangji, cold in nature, bitter return bladder meridian, lung channel, have the effect of inducing diuresis for removing edema, wind-expelling pain-stopping, chemical component master
To be a variety of alkaloids, such as menispermine, Fangohinoline, root of fangji guest alkali, menisine, first menisarine, remove first Mooney Sa
Appoint alkali etc., pharmacological action is analgesia, anti-inflammatory, antiallergy, antibacterial, pest-resistant, antitumor etc..
Tourmaline
Tourmaline, also known as tourmaline have natural thermoelectricity and piezoelectric effect, form resonance sympathetic response by human magnetic field, and
Thermal energy, anion, far infrared light wave can be continuously discharged by human body self-energy, is used for a long time, blood-activating analgetic increases body
Phenomena such as ability to bear, alleviation joint transition strain, aging.
Tourmaline in the application is purchased from Hebei Lingshou County Mao Chuan mineral products processing factory.
It is in some preferred embodiments, by weight, described that prepare raw material also include 50~70 parts of radix rehmanniae preparata, Chinese ephedra
20~40 parts, 20~40 parts of asarum.
It is in some preferred embodiments, by weight, described that prepare raw material also include 60 parts of radix rehmanniae preparata, Chinese ephedra 30
Part, 30 parts of asarum.
Radix rehmanniae preparata
Radix rehmanniae preparata is medicinal material of the Radix Rehmanniae after processing, and slightly warm in nature is sweet in flavor, return liver warp, kidney channel, has nourishing yin and supplementing blood, strengthening the essence
The effect of filling out marrow contains a small amount of cyclenes ether circle constituents in chemical component, such as motherwort glucoside, Aucubin, Catalpol, glutinous rehmannia
Glucoside, the appropriate double glucosides of U.S. benefit, rehmanin, the smelly formaldehyde glucoside of glutinous rehmannia chlorination etc., there are also monoterpene ingredient, such as burnt rehmanin, burnt glutinous rehmannia lactone, coke
Jiofuran, burnt glutinous rehmannia lactone, burnt jiofuran, glutinous rehmannia hardship glucoside member etc..Pharmacological research shows that radix rehmanniae preparata has anti-aging, hemostasis
The effects of enriching blood.
Chinese ephedra
Chinese ephedra, warm-natured, acrid flavour, slight bitter, distributed in lung channel, bladder meridian have sweating cold dispelling, freeing lung and relieving asthma, the function of inducing diuresis for removing edema
Effect, chemical component is mainly alkaloid, such as ephedrine, d-pseudo-ephedrine, methylephedrine, methyl pseudoephedrine, ephedine,
Also include catechotannin, contains terpinol in volatile oil.Pharmacological research shows that Chinese ephedra has quasi- adrenal gland energy to cardiovascular system
Effects on neural system;Have to respiratory system relieving asthma, antibechic, phlegm-dispelling functions;Sweat gland secretion can be made to increase;With apparent diuresis;
With anti-allergy action and certain anti-inflammatory effect;With refrigeration function and different degrees of resisting pathogenic microbes effect;
Can excitor nerve maincenter, influence nervimuscular transmitting;Energy antiallergy, infected by influenza have inhibiting effect;Chinese ephedra oil emu has
Analgesic activity.
Asarum
Asarum, warm-natured, acrid flavour, thoughts of returning home warp, lung channel, kidney channel, the function with wind-dispelling, cold dispelling, sensible analgesic, warm lung eliminating the phlegm
Effect, chemical main component is methyl eugenol, eucarvone, safrole, nopinene, australene, borneol, different anisole, thin
Monooctyl ester element etc..In addition, still removing potassium coclaurine containing a kind of racemization-, microelement has potassium, sodium, magnesium, calcium, iron, manganese, copper, zinc etc..Carefully
It is pungent to have local anaesthesia effect, there is a degree of inhibiting effect to arthritis, also there is certain bacteriostasis, there is enhancing lipid
Metabolism and the effect for increasing blood glucose adjust body smooth muscle function;Volatile oil can be such that anesthetized animal blood pressure declines, and decoction then makes
Blood pressure rises;And have anti-inflammatory and anticonvulsant action;There are also analgesia, calmness, inhibit fever, antipyretic, antihistamine and antiallergic action
With excited respiration.
By adding radix rehmanniae preparata, Chinese ephedra, three taste Chinese medicine of asarum in the plaster composition for the treatment of sciatica, help to control
The deficiency of yang chronic waist-leg pain is treated, the possible reason is can mend since radix rehmanniae preparata, Chinese ephedra, asarum belong to the medicine of warm-natured acrid flavour/sweet
Sun improve the deficiency of yang, and chronic sympton be continuous should not use strong medicine, this three taste just can be improved mildly and discongest continuous symptom.
In some preferred embodiments, described to prepare raw material also and include 50~70 parts of radix rehmanniae preparata, 20~40 parts of Chinese ephedra, thin
Pungent 20~40 parts, 40~60 parts of Bi Bo, 50~70 parts of Hua Chuan.
In some preferred embodiments, it is described prepare raw material also and include 60 parts of radix rehmanniae preparata, 30 parts of Chinese ephedra, 30 parts of asarum,
50 parts of Bi Bo, 60 parts of Hua Chuan.
Bi Bo
Bi Bo also known as fructus piperis longi, property heat, acrid flavour return stomach meridian, large intestine channel, have the effect of warming spleen and stomach for dispelling cold, lower gas analgesic,
The main amide containing class compound of chemical component, lignanoid, volatile oil, piperine, tetrahydropiperic acid, palmitinic acid, the bright peaceful alkali of fructus piperis longi,
The ingredients such as long handle piperine, piplartine.The alcohol extract of Bi Bo has antiulcer, function of resisting myocardial ischemia;Volatile oil is resistant to the heart
Not normal, Adjust-blood lipid is restrained, and nervous centralis can be inhibited;In addition, its there are also the works such as resist oxygen lack, calmness, analgesia, antipyretic, broad-spectrum antiseptic
With.
Hua Chuan
Hua Chuan, i.e. fructus zanthoxyli, warm-natured, acrid flavour, converge to the spleen channel, stomach meridian, kidney channel have the effect of warm in pain, desinsection is antipruritic,
Containing limonene, cumic alcohol, Geraniol etc. in its volatile oil, also contains and remove 1, 8-Cineole, laurene, kokusaginine, seven leaves
The ingredients such as lactone, anethole, thujene.Pharmacological evaluation shows that Hua Chuanke has with anti-experimental character gastric ulcer, to intestinal smooth muscle movement
Two-way function, anti diar rhea, liver protection, calmness is anti-inflammatory, local anaesthesia, anticoagulation, kills itch mite;Pericarp injection has analgesic, anesthesia to make
With;Geraniol can cause intestine in vitro to be wriggled in a small amount, largely then be allowed to inhibit;Water decoction is to streptococcus, staphylococcus, pneumonia
Coccus, bacillus anthracis, hay bacillus, comma bacillus, paratyphosum Bacterium and Pseudomonas aeruginosa have inhibiting effect.
By adding radix rehmanniae preparata, Chinese ephedra, asarum, Bi Bo, Hua Chuan in the plaster composition for the treatment of sciatica, facilitate
It is warming channel and expelling cold, the reason is that since this few taste medicine has the benefits of middle benefit gas cold air can be dispelled, there are also analgesic effects, and the plaster
For therapentic part be at ischium pelvic cavity therefore also there is good therapeutic effect for menalgia.
The second aspect of the present invention provides a kind of plaster for treating sciatica, prepares raw material including at least above-mentioned
Plaster composition;The raw material for preparing also includes plaster substrate, and by weight, the raw material for preparing of plaster substrate at least wraps
Contain: 270~330 parts of lanolin, 0.01~0.1 part of azone, 0.01~0.3 part of borneol, 0.01~0.2 part of menthol, camphor
0.01~0.1 part.
In some preferred embodiments, by weight, the raw material for preparing of the plaster substrate includes at least: wool
300 parts of rouge, 0.05 part of azone, 0.2 part of borneol, 0.12 part of menthol, 0.06 part of camphor.
Lanolin
Lanolin has faint stink to be attached to a kind of secretion grease on wool, and main component is sterols, rouge
The fatty acid ester generated of fat alcohols and triterpene alcohols and about equivalent, accounts for about 95%, also contains free alcohol 4%, and have
A small amount of free fatty acid and hydrocarbons.Use lanolin as plaster substrate, can make main rapidly by mucous membrane and skin
It absorbs, there is adhesive force, property is stablized, is not easy rancid.
In some preferred embodiments, the plaster prepares spina gleditsiae in raw material, rhizoma atractylodis, lanolin, Tourmaline
Weight ratio be (1~3): 1:(18~22): (8~12);It is further preferred that the spina gleditsiae, rhizoma atractylodis, lanolin, Tuo Ma
The weight ratio of beautiful jade is 2:1:20:10.
Lanolin in the application is purchased from Henan Xin Long Biotechnology Co., Ltd.
Azone
Azone is smeared, the penetrating agent of massage for common external drug, to oleophylic, hydrophilic medicament and active constituent
Have it is apparent it is transdermal help infiltration to act on, so that keratoderma and lipid is interacted, reduce active principle to cutin lamellar spacing
The phase inversion temperature of middle lipid, increases mobility, reduces the diffusional resistance of drug or active additive in cuticula, therefore
Play the role of very strong rush infiltration.
Azone in the application is purchased from six hue chemical product Co., Ltd of Zhengzhou.
It is found by the applicant that by the compatibility between chinese medicine material component and corresponding matrix, and to spina gleditsiae, rhizoma atractylodis,
Usage ratio between Tourmaline and lanolin etc. is regulated and controled, and the skin that can accelerate to be pasted place is to effective component in plaster
It absorbs, shortens the onset time of plaster, make to reduce patient pain in its short time.Itself the possible reason is, plaster reconcile preparation
In the process, the inside eucaryotic cell structure of the raw materials such as spina gleditsiae, rhizoma atractylodis can be destroyed under the action ofs lanolin, azone etc., and
Sterol, fatty alcohol, triterpene alcohol can promote spina gleditsiae, rhizoma atractylodis etc. under the action of being formed by esters effective component in lanolin
The dissolution of active principle in raw material, and flavonoid glycoside therein, amino acid, Atisine chloride Atractydin, β-cineol, hinesol, hydroxyl atractylone
Etc. promote infiltration to the inside of skin under the interaction of effective components between each other, enhance the absorption of endothelial cell, rise
To wind-expelling and pain-alleviating, invigorate blood circulation clearing damp the effect of.Simultaneously because the unique internal structure of Tourmaline and electrocaloric effect, are subjected to skin conductance
Heat and plaster generate in use pressure effect under, Tourmaline quick release goes out a large amount of negative oxygen ion, and
The far infrared beneficial to human body, human endothelium generate micro-current, promote human metabolism, adjust central nervous system and
Corticocerebral correlation function, antalgic and sedative.In addition, far infrared, micro-current etc. that Tourmaline generates can pass through lanolin
In the ingredients osmosis such as sterol, fatty alcohol, triterpene alcohol under, by effective components such as Atisine chloride Atractydins with conjugated double bond structures
It is transmitted in the traditional Chinese medicinal components internal structure such as rhizoma atractylodis, spina gleditsiae, further destroys its internal compact texture and cell, discharge it
In remaining effective component, be fully dissolved out the effective component in traditional Chinese medicinal components, further improve plaster resultant effect.
Borneol
Borneol, cold in nature, acrid flavour, hardship, thoughts of returning home warp, the spleen channel, lung channel have the effect of inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain, chemistry
Ingredient is borneol, is a kind of terpenoid.Borneol can inhibit central nervous system, show as apparent sedation and analgesia effect,
Promote the growth and division of Deiter's cells;Have anti-inflammatory, antibacterial, antifertility action, can with other drugs such as Tetramethylpyrazine,
Salicylic acid interacts;Topical application has slight stimulation to sensory nerve, has certain analgesic and anti-corrosion to make
With.
Menthol
Peppermint, cool in nature, acrid flavour, distributed in lung channel, Liver Channel have peat-reek, have the effect of dispelling wind-heat, refresh oneself, promoting eruption,
Menthol is the extract of peppermint, acts on skin or mucous membrane, there is refrigerant itching-relieving action, and pharmacological research shows that peppermint has hair
Sweat, it is antipyretic, alleviate gastrointestinal smooth muscle spasmus, stimulating central nervous system, promote respiratory tract glandular secretion and have anti-inflammatory and spasmolysis etc. and make
With;Nerve endings cold receptor can also be stimulated and generate creeping chill, and reversely cause the variation of deep tissue blood vessel and play to property
Anti-inflammatory, analgesic, itching-relieving action;, Gram-negative coccus resistive to gram, bacillus and a variety of viruses have certain inhibition to make
With;Have the function of apparent spasmolysis, hepatoprotective and cholagogic effects, Robust speaker feature and uterus;To angiocarpy, heart can be benumbed, is expanded
Open blood vessel;To respiratory system, there is phlegm-dispelling functions and good antitussive action;Promote Transdermal absorption, can be used for antimicrobial.
Camphor
Camphor, property heat, acrid flavour, thoughts of returning home warp, the spleen channel, have have one's ideas straightened out ward off it is dirty, dehumidify desinsection, warming and odynolysis the effect of, be
A kind of camphane class compound, can stimulating central nervous system system, it is especially pronounced for high-level center;To circulatory collapse or acute heart function
Energy failure has cardiac effect;Its water soluble metabolites plays the role of apparent heart tonifying, boosting and excited breathing;There is temperature to skin
The stimulation and antisepsis of sum;Stimulation to gastrointestinal tract mucosa, low dose make stomach bask and comfortably, largely can then generate evil
Heart vomiting;And there are slight phlegm-dispelling functions.
In some preferred embodiments, the sum of the menthol and the weight of camphor account for lanolin weight 0.03~
0.1wt%;It is further preferred that the sum of the menthol and the weight of camphor account for the 0.06wt% of lanolin weight.
Although lanolin can be by components such as spina gleditsiae, Radix Angelicae Pubescentis, radix aconiti lateralis preparata, cortex cinnamomi, turmeric, rhizoma atractylodis, semen coicis, the roots of fangji very
The effects of merging well, each component therein enabled to give full play to its dispeling wind and dehumidification, invigorating blood circulation analgesia, but due to wool
It is a kind of secretion grease on wool that rouge is practical, and chemical component therein is relatively complicated, is easy to generate patient skin
Quick and stimulation, and lanolin drugloading rate is few, in sticking use process, be especially easy to perspire when being warm in summer and
Cause to slip, to influence the extensive practicability of plaster.It is found by the applicant that by menthol, camphor, wool in plaster substrate
The regulation of the dosages such as rouge can eliminate stink, effectively avoid plaster to trouble in conjunction with the Tourmaline of the specific dosage in the present invention
The allergy and stimulation of person's skin avoid the symptoms such as itch, redness occur after plaster is lied prostrate affected part.
Applicant is it has been unexpectedly found that the dosage and plaster for passing through each ingredient in Reasonable Regulation And Control plaster composition
The dosage of the ingredients such as lanolin, menthol, camphor in matrix, it is possible to prevente effectively from hot day used because plaster densification is airtight
Make the appearance for situations such as being pasted place's skin whitening, fold in journey because of perspiration.It is the possible reason is spina gleditsiae, Radix Angelicae Pubescentis, system are attached
Ingredient in the plaster composition such as son, cortex cinnamomi, turmeric, rhizoma atractylodis the lanolin the effects of under be sufficiently mixed, dissolve out effective component, but
It is that absorb uniform velocity due to the dissolution of these effective components, by Skin Cell variant, and is coated by the traditional Chinese medicinal components
Permeability, film forming when on silk cloth etc. are different, thus each component sufficiently merged Tourmaline, lanolin,
Under interaction between the ingredients such as menthol, after effective component is absorbed by the skin, micropore is left inside ointment, is improved
The breathable moisture permeability of ointment, avoid ointment because hot day perspire due to slips or to skin other injure.
In some preferred embodiments, the weight ratio of the Camphorae and menthue is 1:2.
In some preferred embodiments, the dosage of the camphor accounts for 0.1~0.3wt% of spina gleditsiae dosage;Into one
Step is preferred, and the dosage of the camphor accounts for the 0.2wt% of spina gleditsiae dosage.
It is found by the applicant that by the regulation to amounts of components such as camphor, spina gleditsiae and Tourmalines, can make plaster anti-irritant,
Antianaphylaxis can be further improved, and even help to the healing of wound, and treatment Sciatica is more efficient.It can
Can the reason of be natural camphor, menthol may promote in spina gleditsiae the dissolution of effective component with to the infiltration inside skin, together
The improvement skin allergy and other effects of Shi Keneng synergy Tourmaline.Further, since traditional Chinese medicinal components effective component is in lanolin, nitrogen
Dissolution under the effects of ketone, borneol, by the difference between Skin Cell infiltration rate etc. and caused by micropore so that on skin,
Moisture can be conducted by especially having the skin of wound, avoid the skin of wound fold, impaired due to moisture is excessive, it is thin to accelerate endothelium
The growth of born of the same parents' tissue, promotes wound healing.
In some preferred embodiments, by weight, the raw material for preparing of the plaster substrate also includes: aloes powder
0.1~1 part, 0.1~1 part of Moschus powder;It is further preferred that by weight, the raw material for preparing of the plaster substrate also includes:
0.3~0.5 part of aloes powder, 0.3~0.5 part of Moschus powder.
In some preferred embodiments, the weight ratio of the aloes powder and Moschus powder is 1:1.
In some preferred embodiments, by weight, the raw material for preparing of the plaster substrate also includes: aloes powder
0.4 part, 0.4 part of Moschus powder.
Agalloch eaglewood
Agalloch eaglewood, slightly warm in nature, acrid flavour, hardship return kidney channel, the spleen channel, stomach meridian, and there is promoting qi circulation and relieving pain, warming middle energizer to arrest vomiting, gas of receiving to relieving asthma it
Effect, in volatile oil main component be agarospirol, it is baimuxinic acid, baimuxinal, baimuxinol, dehydrobaimuxinol, white
The ingredients such as radix aucklandiae Furan Aldehydes, suspension culture of Aquilaria sinensis furan alcohol, α-agarofuran, β-agarofuran, anisic acid, the pharmacological research table of agalloch eaglewood
It is bright, intestinal smooth muscle spasm can be released, central nervous system is inhibited, also has the function of calm, analgesia, decompression, antibacterial.
Moschus
Moschus, warm-natured, acrid flavour, thoughts of returning home warp, the spleen channel have the effect of inducing resuscitation of having one's ideas straightened out, blood circulation, swelling and pain relieving, change
It studies point containing muskone, muscopyridine, androstane derivative, cholesterolic compound etc..Pharmacological research shows that Moschus has in excitement
Pivot nerve and revival effect, can excited breathing, acceleration heartbeat, raising blood pressure;It can increase effect of the adrenaline to receptor, and have
To the increasing action of catecholamine;In addition, the effects of there are also heart tonifyings, anti-inflammatory and inhibition vasopermeability.
In some preferred embodiments, the sum of the aloes powder and the weight of Moschus powder account for the 0.2 of lanolin weight
~0.5wt%;It is further preferred that the sum of the aloes powder and the weight of Moschus powder account for the 0.3wt% of lanolin weight.
In some preferred embodiments, the aloes powder and Tourmaline weight ratio are (0.3~0.5): 150;Into
One step is preferred, and the aloes powder and Tourmaline weight ratio are 0.4:150.
It is found by the applicant that suitable aloes powder and Moschus powder are added in plaster, anti-irritant, the antianaphylaxis of plaster can be made
It can be further improved, even help to the healing of wound.Itself the possible reason is, it is effective in aloes powder and Moschus powder
Component may have irritating chemical component to combine with some pairs of skins in plaster traditional Chinese medicinal components, hinder mentioned component
To the effect between the cell tissue in skin and wound, the destruction to the normal cell in skin is avoided.
The third aspect of the present invention provides a kind of preparation method of the plaster of above-mentioned treatment sciatica, including with
Lower step: plaster composition being mixed and beats powder, and powder diameter is 200 mesh, then powder is mixed with plaster substrate and is tuned into paste, most
Ointment is applied on no mycelia cloth afterwards.
Raw medicinal material used in the present invention can be commercially available from shop of Chinese medicines and Chinese Medicinal Materials Markets, and specification meets in country
Medicinal material standards of pharmacopoeia.
Embodiment
Technical solution of the present invention is described in detail by the following examples, but protection scope of the present invention is not limited to
In the embodiment.Raw material use herein is unless otherwise specified commercially available.
Embodiment 1
Embodiment 1 provides a kind of plaster composition for treating sciatica and prepares raw material at least by weight
Include: 30 parts of spina gleditsiae, 9 parts of Radix Angelicae Pubescentis, 9 parts of radix aconiti lateralis preparata, 6 parts of cortex cinnamomi, 16 parts of turmeric, 15 parts of rhizoma atractylodis, 30 parts of semen coicis, the root of fangji 9
Part, 150 parts of Tourmaline.
This example additionally provides a kind of plaster for treating sciatica, prepares raw material and includes at least above-mentioned plaster combination
Object;The raw material for preparing also includes plaster substrate, and by weight, the raw material for preparing of plaster substrate includes at least: lanolin 300
Part, 0.05 part of azone, 0.2 part of borneol, 0.12 part of menthol, 0.06 part of camphor;
By weight, the raw material for preparing of the plaster substrate also includes: 0.4 part of aloes powder, 0.4 part of Moschus powder.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, comprising the following steps: by plaster group
It closes object mixing and beats powder, powder diameter is 200 mesh, then powder is mixed with plaster substrate and is tuned into paste, and ointment is finally applied to nothing
On mycelia cloth.
Embodiment 2
Embodiment 2 provides a kind of plaster composition for treating sciatica, exists with the difference of embodiment 1
In by weight, the raw material for preparing also includes: 60 parts of radix rehmanniae preparata, 30 parts of Chinese ephedra, 30 parts of asarum.
This example additionally provides a kind of plaster and preparation method thereof for treating sciatica, similar to Example 1.
Embodiment 3
Embodiment 3 provides a kind of plaster composition for treating sciatica, exists with the difference of embodiment 2
In by weight, the raw material for preparing also includes: 50 parts of Bi Bo, 60 parts of Hua Chuan.
This example additionally provides a kind of plaster and preparation method thereof for treating sciatica, similar to Example 2.
Embodiment 4
Embodiment 4 provides a kind of plaster composition for treating sciatica, exists with the difference of embodiment 1
In the parts by weight of the spina gleditsiae are 10 parts.
This example additionally provides a kind of plaster and preparation method thereof for treating sciatica, similar to Example 1.
Embodiment 5
Embodiment 5 provides a kind of plaster composition for treating sciatica, exists with the difference of embodiment 1
In the parts by weight of the spina gleditsiae are 50 parts.
This example additionally provides a kind of plaster and preparation method thereof for treating sciatica, similar to Example 1.
Embodiment 6
Embodiment 6 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, the sheep
The parts by weight of hair rouge are 350 parts.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 7
Embodiment 7 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, the sheep
The parts by weight of hair rouge are 250 parts.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 8
Embodiment 8 provides a kind of plaster composition for treating sciatica, exists with the difference of embodiment 1
In the parts by weight of the Tourmaline are 100 parts.
This example additionally provides a kind of plaster and preparation method thereof for treating sciatica, similar to Example 1.
Embodiment 9
Embodiment 9 provides a kind of plaster composition for treating sciatica, exists with the difference of embodiment 1
In the parts by weight of the Tourmaline are 200 parts.
This example additionally provides a kind of plaster and preparation method thereof for treating sciatica, similar to Example 1.
Embodiment 10
Embodiment 10 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described thin
The parts by weight of lotus brain are 0.18 part, and the parts by weight of camphor are 0.09 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 11
Embodiment 11 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described thin
The parts by weight of lotus brain are 0.06 part, and the parts by weight of camphor are 0.03 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 12
Embodiment 12 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described thin
The parts by weight of lotus brain are 0.24 part, and the parts by weight of camphor are 0.12 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 13
Embodiment 13 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described thin
The parts by weight of lotus brain are 0.04 part, and the parts by weight of camphor are 0.02 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 14
Embodiment 14 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described thin
The parts by weight of lotus brain are 0.18 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 15
Embodiment 15 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described thin
The parts by weight of lotus brain are 0.06 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 16
Embodiment 16 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described heavy
The parts by weight of face powder are 0.6 part, and the parts by weight of Moschus powder are 0.2 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 17
Embodiment 17 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described heavy
The parts by weight of face powder are 0.1 part, and the parts by weight of Moschus powder are 0.1 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 18
Embodiment 18 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described heavy
The parts by weight of face powder are 1 part, and the parts by weight of Moschus powder are 1 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 19
Embodiment 19 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described heavy
The parts by weight of face powder are 0.2 part, and the parts by weight of Moschus powder are 0.2 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Embodiment 20
Embodiment 20 provides a kind of plaster composition for treating sciatica, similar to Example 1.
This example additionally provides a kind of plaster for treating sciatica, difference from example 1 is that, it is described heavy
The parts by weight of face powder are 0.6 part, and the parts by weight of Moschus powder are 0.6 part.
This example additionally provides the preparation method of the plaster of above-mentioned treatment sciatica, similar to Example 1.
Performance evaluation
One, the plaster for the treatment of sciatica obtained to embodiment 1-20 carries out curative effect test.
1. diagnostic criteria
1.1 Standards of Chinese Medical Syndrome Differentiation
This disease of tcm syndrome differentiation and treatment common are cold-dampness and coagulate network, damp and hot invade four type such as network, obstruction of collaterals by blood stasis, kidney deficiency and liver.
1.1.1 cold-dampness coagulates network
Syndrome: waist hip duration dull pain, and to release on the outside of thigh rear side, small leg outer side and instep, aggravation of catching cold obtains hot
Pain is slow, and pain does not subtract when reposing.Whitish tongue is greasy, deeptensepulse and it is slow.
Syndrome analysis: it is moist to stagnate because of cold having property of contraction, therefore pain is in duration dull pain, normal and folder ailment said due to cold or exposure, and oriented lower limb
The characteristics of release.Damp being a kind of YIN pathogen, property is viscous, and damp evil is easy to stagnate when reposing, therefore pain does not subtract.Whitish tongue is greasy, deeptensepulse and it is slow,
For cold-dampness stop it is poly- as.
1.1.2 damp and hot invade network
Syndrome: pain in waist and lower extremities is in burn the violent distending pain of sample, thirsty, vexed, red, the yellow and greasy fur of urine, soft and rapid pulse or chord number.
Syndrome analysis: damp and hot to be jammed, blockage of channel, not general rule pain, and feel pain and burn and violent.The inclined Sheng Ze of heat evil occurs
Vexed, thirsty, damp-heat flowing down to the urinary bladder is then urinated red.Yellow and greasy fur, soft and rapid pulse, be it is damp and hot as.
1.1.3 obstruction of collaterals by blood stasis
Syndrome: pain in waist and lower extremities continuing vigorous, cough, solution just, walking make that the pain increased, then pain slightly subtracts sitting and lying bending knee, pain
As pierced, fixed pain, sore spot tenderness, numbness of lower limbs, dark purple tongue, or have ecchymosis, uneven pulse.
Syndrome analysis: due to waist injury, stagnation of blood stasis passages through which vital energy circulates, QI-blood circulation is unsmooth, therefore sees waist-leg constant pain, suffering limb
Muscular constricture bending knee, fixed pain, acutely as pierced, dynamic then bitterly acute and tenderness.Qi and blood retardance, therefore extremity numbness.Dark purple tongue, or have the stasis of blood
Spot, uneven pulse are to stop sign in hemostasis.
1.1.4 kidney deficiency and liver:
Syndrome: pain in waist and lower extremities is touching not to be cured, and radiates downwards, meets labor more very, sleeping then mitigate, leg knee inability, pale tongue, deep thready pulse,
Or the red less fur of tongue, stringy,thready and rapid pulse.
Syndrome analysis: waist is kidney mansion, and Shen controls bone, liver governing tendons, then muscles and bones dystrophy, weakened body resistance heresy enter caused by liver and kidney deficiency, and pain is touching
It is refractory, meet labor more very, sleeping then mitigate, leg knee is powerlessly asthenic symptoms finding.Pale tongue, deep thready pulse be the deficiency of yang as;The red less fur of tongue, arteries and veins
String is counted accurately, is the sign of the deficiency of Yin.
1.2 Western medicine diagnostic criteria
1.2.1 on the basis of certain pathogenesis, acute onset also shows recurrent exerbation.
1.2.2 the clinical common duration radiated downwards from rear side of waist, buttocks, thigh or on rear side of thigh or intermittent pain
Bitterly.
1.2.3 stand, bend over, coughing, the Shi Junke that sneezes aggravates pain, therefore patient often keep a kind of specific positions or
Position.
1.2.4 it checks that sensory disturbance is often unobvious, or only feels obstacle in small leg outer side and foot nervus peronaeus distributed area.
1.2.5 all tender points of sciatic nerve are the positive, and Lasegue's sign and sciatic nerve drawing sign are positive.
1.2.6 tendon reflex weaken or disappear but acute stage can slightly enliven, foot or toes dyskinesia.
1.2.7 chin chest is tested: even patient lies supine, examiner by its neck it is passive it is anteflexion so that lower chin is touched the wall of the chest, such as swash
Hair or aggravation lower limb pain are that the test of chin chest is positive.
2. test method
2.1 group technologies: 400 patients are chosen, random digits table is divided into 20 groups, in gender, age, disease between each group
Journey, state of an illness etc. compare, no significant difference, and every group of patient tries out the treatment sciatica in the same embodiment
Plaster.
2.2 medications: the plaster provided using embodiment 1-20 is pasted 12 hours every time, and daily dressing is primary, is within 15 days
One course for the treatment of treats a course for the treatment of.
2.3 efficacy determinations: recovery from illness-clinical symptoms and sign all disappear, and functional rehabilitation is normal;Effective-sings and symptoms
It is basic to restore, normal activity and work can be participated in;Effectively-sings and symptoms part is restored, and the ability of activity and work has
Improve;In vain-it is not up to effective standard.
2.4 onset times determined: in observing the symptoms, a certain symptom mitigates or the improved time is set to the case medication
Onset time afterwards.
2.5 test results: it is shown in Table 1.
Table 1
Two, the plaster for the treatment of sciatica obtained to embodiment 1-20 carries out smell, skin irritation, wound skin
Skin irritation, docile degree, skin whiting, the subjective assessment of a crease in the skin situation, estimator is above-mentioned each group patient, and result is
The opinion that each group patient reaches an agreement, is shown in Table 2.
Table 2
Three, the treatment case of embodiment
1. case one: patient gold so-and-so, male, 53 years old.
It tells: cervical vertebra medical history 2 years, aggravating recently.
Existing disease: cervical pain is with stiff, dizziness, and random thoughts headache, the right numbness of fingers, stool and urine is normal, and red tongue body tongue fur is thin, arteries and veins
It is sliding, it distinguishes as caused by liver and kidney deficiency, cold-evil attacks outside.
Press: cervical spondylosis is common disease, frequently-occurring disease.Its cause of disease yang-energy is weak, marrow sea deficiency, and exogenous disease wind, cold, wet, and three is evil
Passages through which vital energy circulates is caused to stop up stagnant obstructed, not general rule pain." excess in the upper and deficiency in the lower " summarizes exactly that " stomach Qi does not drop, unrising of splenoqi, kidney qi from Chinese medicine angle
Do not hide ", essence is the insufficiency of both the spleen and the kindey, cannot the warm lower part of the body on sun floats on.Excess in the upper and deficiency in the lower, guiding fire to origin is the best approach, makes gas past
Under walk.
The rules for the treatment of: warm nourishing liver and kidney, clearing and activating the channels and collaterals.
Medication: the plaster that embodiment 1 obtains is pasted on the acupuncture point middle part of gastric cavity, Guan Yuan, Qihai.
Therapeutic effect: continuous application is fully recovered for ten days.
2. case two: patient Lee, male, 49 years old.
Tell: CT makes a definite diagnosis the lumbar vertebrae protrasion of the lumbar intervertebral disci before, and effect of seeking medical advice in many ways is good or bad, and weather is gradually cool recently, pain
Pain is obvious to be aggravated, and February is more, enters consulting room by back.
Existing disease: Low Back Pain is cut along right leg to foot pain such as knife, and night weight, heat mitigates, then weighs to the cold, right side limb muscle atrophy,
Pi Wen is low, and diet is fine, and two is just as usual, pale tongue with white fur, the deep and slow inability of pulse condition, deficiency of yang cold-dampness.
Medication: the plaster that embodiment 1 obtains is pasted on acupuncture point Zusanli, Sanyinjiao, spring.
Therapeutic effect: pain in the loins is cured, and follow-up 5 years is not repeatedly.
3. case three: Mr. Wang, male, 27 years old, worker.
Tell: two years ago pain in the loins, CT examination due to Overexertion are diagnosed as protrusion of lumber intervertebral disc pressuring nerve, alleviate through treatment,
Recently because catching cold, slight illness recurs again.
Existing disease: whole body is tired, arthralgia, is diffused with left lower extremity along sciatic nerve territory, in great pain, moans ceaselessly,
Daytime light night weight, heat is then light, helps into consulting room, channel, physical therapy etc. of short duration can be alleviated, and pale tongue is too white greasy, floating and tense pulse, and the cold of insufficiency type is wet
In table.
Medication: the plaster that embodiment 1 obtains is pasted on acupuncture point Zusanli, Sanyinjiao, spring.
Therapeutic effect: more, follow-up in 4 years is not recurred.
4. case four: hole, male, 54 years old, civil servant.
Tell: gout is for many years.On March 1st, 2018 because feeding the unexpected pain swelling of midnight right knee joint such as beefsteak, red wine,
Color of the leather is unchanged, tenderness, joint stuffiness, and difficulty in walking is upper downstairs to become apparent from.
Existing disease: deeptensepulse, pale tongue with thin fur is white, indentation.Soldier in joint, middle phlegm card, phlegm wet.
Medication: the plaster that embodiment 3 obtains is pasted on affected part and backbone paravertebral point, Changqiang acupoint, SHANZHONG acupoint, spring paste
It applies.
Therapeutic effect: symptom is substantially reduced within three days, and continuously sticks two months and enjoin the high food of seafood purine of giving up alcohol
So far more than a year without morbidity.
5. case five: Cao, male, 47 years old.
It tells: gout 8 years, aggravating within nearly 2 years left ankle-joint and the first tarsometatarsal joint of bilateral swells and ache throughout the year, pain of walking wears shoes
It is difficult.
Existing disease: recurrent exerbation is suffered untold misery, and shape is cold to fear cold, the cool soreness of waist of limb, not yearningly, pale tongue, whitish tongue, fat profit neatly, tooth
Trace.Deep thready pulse.Uric acid 706mmol/L, first YANG deficiency, stagnation of cold-damp passages through which vital energy circulates, disorder of meridian-QI.
Medication: the plaster that embodiment 3 obtains is pasted on affected part and backbone, Changqiang acupoint, Danzhong, Shenque, Guan Yuan, three yin
Friendship, Zusanli, Yongquan acupoint.
Therapeutic effect: five days painful recoveries, freely, painful swelling of joints disappears for walking, and uric acid is near normal.
6. case six: finish certain, female, 34 years old, teacher.
Tell: first visit on May 8 in 2018, menstrual period pain, brown sugar jujube Jiang Shui are alleviated, and menses have a large amount of clots, and appetite is just
Often, amount of drinking water is few, not thirsty but cool drink fruit, avoids cold drink as far as possible, stool and urine rule, it is a little difficult to fall asleep, and nearly March is about
12 points or so sleeps, shallowly sleep dreaminess.Normal condition is not cold, and only menstrual period are cold, loose stool.It is not easy to perspire, often feels out of strength, marriage two
Year more unpregnancies.
Existing disease: the fat profit trace of tongue, tongue fur is thin white, and tongue nature is slightly dark, the shaoyin disease uterus cold of insufficiency type.
Medication: the plaster that embodiment 3 obtains is pasted on SHANZHONG acupoint, SHENQUE acupoint, Guanyuan point, Sanyinjiao, Zusanli, spring
The cave area , Ba Liao sticks for continuous three months, and enjoins wind sheltering is cold to avoid eating all raw and cold foods.
Therapeutic effect: by the end of May, in the period, no pain, medium through measuring, color is scarlet, no clot;By the end of June, eumenorrhea;8
The middle of the month makes a definite diagnosis pregnancy.
7. case seven: Zhang, female, 17 years old.
Tell: on July 20th, 2018 examines, dysmenorrhea, cold and pain in the lower abdomen tenderness, and amount is few, and dark through color, usually underbelly is cold.
Existing disease: pale tongue deeptensepulse.
Medication: the plaster that embodiment 3 obtains is pasted on MINGMEN acupoint, Changqiang acupoint, SHENQUE acupoint, Guanyuan point.
Therapeutic effect: it is premenstrual, pain relief in five days is sticked in;Before continuing on through, in stick two menstrual bloods scarlet, amount is just
Often.Underbelly temperature.
From above test result and case it is known that a kind of plaster for treating sciatica provided by the invention is logical
The proportion in plaster composition and plaster substrate between each raw material is overregulated, so that onset time and therapeutic effect reach most preferably,
Patient's slight illness can quickly be mitigated and cured completely;In addition, the plaster in the present invention does not have peculiar smell, drugloading rate is high, stingless to skin
Swash, can fit together well with skin, comfortable ventilating, will not cause skin whiting, fold the problems such as.The present invention is for controlling
It treats except sciatica, equally has good therapeutic effect, such as dysmenorrhea, gout disease to other illnesss.
At last it is pointed out that the foregoing is merely illustrative of the preferred embodiments of the present invention, it is not intended to limit the invention, it is all at this
Made any modifications, equivalent replacements, and improvements etc., should be included in protection model of the invention within the spirit and principle of invention
Within enclosing.
Claims (10)
1. a kind of plaster composition for treating sciatica, which is characterized in that by weight, prepare raw material and at least wrap
Contain: 20~40 parts of spina gleditsiae, 5~15 parts of Radix Angelicae Pubescentis, 5~15 parts of radix aconiti lateralis preparata, 1~10 part of cortex cinnamomi, 10~20 parts of turmeric, rhizoma atractylodis 10~
20 parts, 20~40 parts of semen coicis, 5~15 parts of the root of fangji, 130~170 parts of Tourmaline.
2. the plaster composition for the treatment of sciatica as described in claim 1, which is characterized in that by weight, described
Preparing raw material also includes 50~70 parts of radix rehmanniae preparata, 20~40 parts of Chinese ephedra, 20~40 parts of asarum.
3. the plaster composition for the treatment of sciatica as described in claim 1, which is characterized in that by weight, described
Preparing raw material also includes 50~70 parts of radix rehmanniae preparata, 20~40 parts of Chinese ephedra, 20~40 parts of asarum, 40~60 parts of Bi Bo, Hua Chuan 50~70
Part.
4. a kind of plaster for treating sciatica, which is characterized in that it prepares raw material and includes at least such as claims 1 to 3 times
Plaster composition described in one;The raw material for preparing also includes plaster substrate, and by weight, plaster substrate prepares raw material
Include at least: 270~330 parts of lanolin, 0.01~0.1 part of azone, 0.01~0.3 part of borneol, 0.01~0.2 part of menthol,
0.01~0.1 part of camphor.
5. the plaster for the treatment of sciatica as claimed in claim 4, which is characterized in that the weight of the menthol and camphor
The sum of account for 0.03~0.1wt% of lanolin weight.
6. as claimed in claim 4 treatment sciatica plaster, which is characterized in that it is described prepare spina gleditsiae in raw material,
Rhizoma atractylodis, lanolin, Tourmaline weight ratio be (1~3): 1:(18~22): (8~12).
7. the plaster for the treatment of sciatica as claimed in claim 4, which is characterized in that by weight, the plaster base
The raw material for preparing of matter also includes: 0.1~1 part of aloes powder, 0.1~1 part of Moschus powder.
8. the plaster for the treatment of sciatica as claimed in claim 7, which is characterized in that the weight of the aloes powder and Moschus powder
Amount is than being 1:1.
9. the plaster for the treatment of sciatica as claimed in claim 7, which is characterized in that the weight of the aloes powder and Moschus powder
The sum of amount accounts for 0.2~0.5wt% of lanolin weight.
10. a kind of preparation method of the plaster of the described in any item treatment sciatica of such as claim 4~9, feature exist
In, comprising the following steps: plaster composition is mixed and beats powder, powder diameter is 200 mesh, then powder is mixed tune with plaster substrate
At paste, finally ointment is applied on no mycelia cloth.
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WO2021219255A1 (en) * | 2020-04-29 | 2021-11-04 | Organoid Technologies Gmbh | Natural material pad |
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