CN104984049A - Traditional Chinese medicine capsule for treating severe acute pancreatitis - Google Patents
Traditional Chinese medicine capsule for treating severe acute pancreatitis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine capsule for treating severe acute pancreatitis. The capsule is prepared from the following traditional Chinese medicinal materials in parts by weight: 9 parts of rhubarb, 5 parts of natrii sulfas, 6 parts of fructus aurantii immaturus, 6 parts of wild persimmon, 3 parts of wild cumin, 3 parts of cattle lungs, 4 parts of rhizoma atractylodis macrocephalae, 3 parts of leaves of Chinese ilex, 4 parts of aizoon stonecrop herb, 4 parts of prepared common monkshood daughter roots, 5 parts of sapium baccatum roots, 4 parts of mesua ferrea flowers, 12 parts of yellow soybeans, 3 parts of radix glycyrrhizae, 4 parts of akebia stems, 3 parts of radix salviae miltiorrhizae, 4 parts of cortex magnoliae officinalis, 3 parts of halenia elliptica, 4 parts of dandelion, 4 parts of cape jasmine, 3 parts of radix ceratostigmae, 4 parts of fructus liquidambaris, 6 parts of wild semen canavaliae, 8 parts of rhizoma polygonati, 8 parts of roots of straight ladybell, 6 parts of radix ophiopogonis, 8 parts of fructus lycii, 6 parts of radix paeoniae alba and 6 parts of pine pollen disruption powder. Proved by clinical experiments, through the selection of appropriate medicinal materials and proportion thereof, the capsule achieves the remarkable efficacy of treating severe acute pancreatitis, and is safe and free of toxic and side effects.
Description
Technical field
The present invention relates to a kind of Chinese medicinal capsule, be specifically related to a kind of Chinese medicinal capsule being used for the treatment of Severe Acute Pancreatitis SAP.
Background technology
Severe Acute Pancreatitis SAP (SAP) is one of Medicine and Surgery emergency and severe disease, and its onset is anxious, and state of an illness weight, complication is many, and mortality rate is high.In the treatment of SAP, there is significant progress in recent years, but also there is no the reliable and effective Therapeutic Method of well-known security.Treatment for Severe Acute Pancreatitis SAP still lacks the effective medicine of generally recognized as safe at present.
Summary of the invention
The present invention aims to provide a kind of Chinese medicinal capsule being used for the treatment of Severe Acute Pancreatitis SAP and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to treating Severe Acute Pancreatitis SAP, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicinal capsule being used for the treatment of Severe Acute Pancreatitis SAP, be prepared from by the Chinese crude drug of following weight proportion: Radix Et Rhizoma Rhei 9 parts, 5 parts, Natrii Sulfas, Fructus Aurantii Immaturus 6 parts, wild Fructus Kaki 6 parts, wild Fructus Cumini Cymini 3 parts, pulmonis Bovis seu Bubali 3 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Folium Ilicis Purpureae 3 parts, Herba Sedi Aizoon 4 parts, Radix Aconiti Lateralis Preparata 4 parts, Sapium baccatum Roxb 5 parts, ferreous mesua spends 4 parts, Semen Glycines 12 parts, 3 parts, Radix Glycyrrhizae, Caulis Akebiae 4 parts, Radix Salviae Miltiorrhizae 3 parts, Cortex Magnoliae Officinalis 4 parts, Halenia elliptica D. Don 3 parts, Herba Taraxaci 4 parts, Fructus Gardeniae 4 parts, Radix ceratostigmatis willemottiani 3 parts, Fructus Liquidambaris 4 parts, wild Semen Canavaliae 6 parts, Rhizoma Polygonati 8 parts, Radix Adenophorae (Radix Glehniae) 8 parts, Radix Ophiopogonis 6 parts, Fructus Lycii 8 parts, the Radix Paeoniae Alba 6 parts, breaking cellular wall Pollen Pini 6 parts.
Preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Radix Et Rhizoma Rhei [source] this product is the dry root and rhizome of polygonum rheum palmatum.[nature and flavor] are bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.
Natrii Sulfas [source] Sulfates mineral Natrii Sulfas race Natrii Sulfas, through the crystalline solid of processing and refining.Pulverize is used as medicine.[nature and flavor] are salty, bitter, cold.[return through] returns stomach, large intestine channel.[function cures mainly] purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat.
The dry young fruit of Fructus Aurantii Immaturus [source] rutaceae Citrus aurantium Linn. and variety or Fructus Citri sinensis.[function cures mainly] dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.
The root that wild Fructus Kaki [source] is the wild Fructus Kaki of Ebenaceae plant, branch and leaf.[nature and flavor] bitter in the mouth, puckery, gas is fragrant.Cold in nature.[function cures mainly] nurses one's health four towers, mends native stomach invigorating, Qinghuo Jiedu.Cure mainly weak, anorexia, weak and sickly, drought declines, jaundice, burn due to hot liquid or fire.
Wild Fructus Cumini Cymini [source] is the seed of the wild Fructus Cumini Cymini of umbrella section plant.[nature and flavor] three grades are xeothermic, acrid in the mouth.[function cures mainly] raw dry heat-dissipating, strong muscle is good for flesh, except the insane hysteria that disappears, cold-dispelling pain-relieving, warming the lung to relieve cough, drying dampness to eliminate phlegm, diuresis and expelling stone, dispelling wind for relieving itching, stasis-resolving spot-removing.Cure mainly humid or lymphatic temperament disease, as paralysis, disease of flaccid muscles, epilepsy, hysteria, marrow arthralgia, size arthralgia, sciatica, cold cough, moist abundant expectoration, renal calculus, tinea capitis, skin pruritus, various speckle warts etc.
Pulmonis Bovis seu Bubali [source] medical material Ji Yuan: be the lung of bovid cattle or Babalus bubalis L..[nature and flavor] sweet in the mouth; Property is put down.[return through] lung meridian.[function cures mainly] lung benefiting; Cough-relieving is breathed heavily.Main cough due to deficiency of the lung's dyspnea.
The Rhizoma Atractylodis Macrocephalae [source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
The blade that Folium Ilicis Purpureae [source] is holly plant Ilicis Purpureae.[chemical analysis] leaf is containing two kinds of antipathogenic compositions, and one of them is protocatechuic acid, separately containing volatile oil, flavonoid.[nature and flavor] are pained, cold.[function cures mainly] controls scald, ulcer disunion of a specified duration, thromboangiitis obliterans, acute and chronic bronchitis, pneumonia, urinary tract infection, and bacillary dysentery, traumatic hemorrhage, freezes chilblain, chaps.
Herba Sedi Aizoon [source] medical material Ji Yuan: be root or the herb of crassulaceae plants Herba sedi kamtschatici, horizontal root Herba sedi kamtschatici.[nature and flavor] put down; Sweet; Micro-acid.[return through] heart; Liver; Spleen channel.[function cures mainly] dissipating blood stasis; Hemostasis; Mind tranquilizing and the heart calming; Removing toxic substances.Main haematemesis; Epistaxis; Have blood in stool; Hematuria; Metrorrhagia; Purpura; Traumatic hemorrhage; Traumatic injury; Cardiopalmus; Insomnia; Furuncle carbuncle; Burn and scald; Insect bite.
The processed goods of the daughter root of Radix Aconiti Lateralis Preparata [source] ranunculaceae plant Aconitum carmichjaelii Debx..[nature and flavor] are pungent, sweet, hot greatly; Poisonous.[return through] GUIXIN, kidney, spleen channel.[function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
The root that Sapium baccatum Roxb [source] is euphorbia plant Sapium baccatum Roxb.[nature and flavor] taste is micro-puckery, and property is put down.[function cures mainly] adjusts benefit four tower, and regulating menstruation and activating blood, mends native stomach invigorating, promoting the circulation of QI to relieve pain.How sick, weak cure mainly and have a delicate constitution, menstruation point is adjusted, dysmenorrhea, amenorrhea, abdominal distention, anorexia.
Ferreous mesua spends [source] is the flower of Garcinia maingayii ferreous mesua.[nature and flavor] secondary is xeothermic, bitter in the mouth.[function cures mainly] raw dry heat-dissipating, temperature compensation heart, the refreshing heart pleases will, warm-up tonifying YANG, and dampness mends stomach, and antidiarrheal, holds back wound, the hemorrhoid that disappear of stopping blooding.Cure mainly raw property or lymphatic temperament disease, have a guilty conscience as cold, depression, neurasthenia, coldness of the body YANG excess, moist insufficiency of stomach, diarrhoea and various wet wound, bleeding hemorrhoids etc.
Semen Glycines [source] medical material Ji Yuan: be the seed of the seed coat yellow of legume soybean.[nature and flavor] are sweet; Flat.[return through] spleen; The heart; Large intestine channel.[function cures mainly] invigorating spleen for diuresis; Alleviating distention in middle-JIAO intestinal stasis relieving; Removing toxic substances and promoting subsidence of swelling.Staple food amasss dysentery; Abdominal distention food is slow-witted; Sore and toxic; Edema due to deficiency of the spleen; Traumatic hemorrhage.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume.[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Caulis Akebiae [source] is plants of Lardizabalaceae Caulis Akebiae or threeleaf akebia, the woody stems of Caulis Akebiae.[nature and flavor] are bitter; Cold in nature.[return through] heart; Spleen; Kidney; Small intestinal; Urinary bladder channel.[function cures mainly] clearing away heat and promoting diuresis; Blood circulation and channel invigorating.Main red urine is red; Stranguria with turbid discharge; Edema; Irritable feverish sensation in the chest; Larynx larynx pain; Aphtha of the mouth and tongue; Rheumatic arthralgia; Galactostasis; Amenorrhea; Dysmenorrhea.
Radix Salviae Miltiorrhizae [source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
The dry dried bark of Cortex Magnoliae Officinalis [source] Magnoliacea plant Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils., root bark and branch skin.The expectorant of [function cures mainly] dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
The wounded in the battle herb that Halenia elliptica D. Don [source] is gentianaceae plant Halenia elliptica D. Don.[nature and flavor] bitter in the mouth, cold in nature.[function cures mainly] presses down association's day, and heat clearing away, cures the wound, stomach invigorating.Cure mainly association's day heat, liver-heat, plague fever, internal organs heat.
Herba Taraxaci [source] this product is feverfew Herba Taraxaci or the dry herb belonging to several plants together.[nature and flavor] are bitter, sweet, cold.[return through] returns liver, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Fructus Gardeniae [source] this product is the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae.[nature and flavor] are bitter, cold.[return through] GUIXIN, lung, tri-jiao channel.[function cures mainly] pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles.
The root that Radix ceratostigmatis willemottiani [source] is Plumbaginaceae plant Radix ceratostigmatis willemottiani.[nature and flavor] are warm in nature, sweet in the mouth.[function cures mainly] promoting blood circulation and stopping pain, blood stasis dispersing and fresh blood promoting.
Fructus Liquidambaris [source] this product is the drying and ripening infructescence of Hamamelidaceae Plants Chinese sweet gum.[nature and flavor] are bitter, flat.[return through] returns liver, kidney channel.[function cures mainly] dispelling, collateral-activating, diuretic stimulates the menstrual flow.For arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.
The seed of the wild Semen Canavaliae of wild Semen Canavaliae [source] leguminous plant and root.[nature and flavor] taste is sweet.Property is put down.Enter four towers.[function cures mainly] adjusts benefit four tower, Qinghuo Jiedu, killing parasites for relieving itching.Cure mainly have a delicate constitution how sick, weak, anorexia, insomnia, furuncle carbuncle furuncle abscess, skin pruritus, macule, scabies, eczema.
Rhizoma Polygonati [source] medical material Ji Yuan: be the rhizome of liliaceous plant Rhizoma Polygonati, Polygonatum cyrtonema Hua and P. kingianum.[nature and flavor] are sweet; Flat.[return through] spleen; Lung; Kidney channel.[function cures mainly] nourishing YIN and moistening the lung; Invigorating the spleen and replenishing QI, Zishen fill fine.Main deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body void is won thin; Wind favus disease.
Radix Adenophorae (Radix Glehniae) [source] is campanulaceae Lady bell plant four leaf Radix Adenophorae (Radix Glehniae) or its congener, is used as medicine with root.[nature and flavor] are sweet, cool.[function cures mainly] clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick.
Radix Ophiopogonis [source] this product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf).[nature and flavor] are sweet, and micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
The dry mature fruit of Fructus Lycii [source] plant of Solanaceae lycium barbarum.[nature and flavor] are sweet, flat.[return through] returns liver, kidney channel.[function cures mainly] nourishing the liver and kidney, replenishing vital essence to improve eyesight.
The Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Breaking cellular wall Pollen Pini [source] medical material Ji Yuan: Pollen Pini is the spermatid of pinaster pistil, having another name called pine yellow, is pure, the dry pollen that pick up from China indigenous tree pinaceae plant Pinus massoniana Lamb.[function cures mainly], containing the whole active nutritional compositions needed for life entity, comprising multiple proteins, aminoacid, mineral, enzyme and coenzyme, nucleic acid, monosaccharide, polysaccharide etc., total content reaches more than 200 and plants.Also nearly hundred kinds of enzymes, biotin, nucleic acid, cellulose, unsaturated fatty acid, Flavonoid substances, rutin isoreactivity materials are contained in addition in Pollen Pini.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment Severe Acute Pancreatitis SAP cure rate high and safe without toxic side effect, and can related complication be prevented.When compatibility is applied, owing to there is interactional relation between medicine and medicine, so some medicine promotes curative effect because of synergism, but also some medicine but may resist mutually and offset, weakens original effect; Some medicine alleviates because of mutual adapted or eliminates toxicity or side effect, but also some medicine makes effect of declines or unfavorable human body etc. because of interacting on the contrary, it is namely so-called single file, mutual reinforcement between, the mutual-assistance, mutual restraint between two drugs, the mutual-detoxication, the mutual inhibition, contrary.The compound recipe composition of the traditional Chinese medical science is a kind of type of organization playing Chinese Herbs, and its superiority is exquisite monarch, four natures and five flavors of drug lifting, by organic cooperation of medicine, reaches the curative effect improving medicine, and weakens the object of its adverse side effect.For the present invention, the combination of listed medical material, neither simply pile up between medical material, neither the addition of similar drug effect, but have certain combination principle, between formula medical material, compatibility is rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.Herba Taraxaci heat-clearing and toxic substances removing, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling in the present invention, Folium Ilicis Purpureae anti-inflammation is monarch drug with pulmonis Bovis seu Bubali altogether; Add with Radix Et Rhizoma Rhei clearing up internal heat by using drugs of bitter in taste and cold in nature, cleanse gastrointestinal, rush down knot relieving constipation, Natrii Sulfas is salty-cold, moistening for dryness and softening hard mass, helps Radix Et Rhizoma Rhei purging heat to relax the bowels, the broken knot of Cortex Magnoliae Officinalis, the Fructus Aurantii Immaturus therapeutic method to keep the adverse QI flowing downwards, the smooth gas of purging FU-organs, both can relieving distension and oppression, helped again nitre Huang to push away to swing stagnant, four medicines match, and can rush down lower accumulation of heat, and the domination of pathogen is all gone, and internal organs gas is unobstructed.On this basis, Radix Et Rhizoma Rhei is the turbid descending key medicine, has the power of turbid purging FU-organs of dispelling, precisely because cold, clothes of a specified duration must cut down kidney yang, and Radix Aconiti Lateralis Preparata is hot, function temperature cold expelling turbid and opening and closing knot, and can Radix et Rhizoma Rhei (processed) cold and deposit its property of walking to let out, the same use of two tastes, becomes warm cold expelling turbid, the agent of dispersing the stagnated pathogen with pungent drugs and lowering the adverse QI with bitter drugs altogether, and plays the merit of clearance except lattice.Help with conditioning QI of five ZANG-organs such as wild Semen Canavaliae, Rhizoma Polygonati, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Fructus Lycii, the Radix Paeoniae Albas cloudy, reduce concurrent syndrome.Separately strengthen immunity with breaking cellular wall Pollen Pini, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.In addition, medicine its effects in the treatment of primary disease such as ferreous mesua spends, Herba Sedi Aizoon, Semen Glycines, Fructus Liquidambaris, Radix ceratostigmatis willemottiani are also very important, because medication is proper, further ensure the thorough radical cure of primary disease and prevent recurrence.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, and for prevent disease progress, in invade internal organs and also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix Et Rhizoma Rhei 9g, Natrii Sulfas 5g, Fructus Aurantii Immaturus 6g, wild Fructus Kaki 6g, wild Fructus Cumini Cymini 3g, pulmonis Bovis seu Bubali 3g, Rhizoma Atractylodis Macrocephalae 4g, Folium Ilicis Purpureae 3g, Herba Sedi Aizoon 4g, Radix Aconiti Lateralis Preparata 4g, Sapium baccatum Roxb 5g, ferreous mesua spend 4g, Semen Glycines 12g, Radix Glycyrrhizae 3g, Caulis Akebiae 4g, Radix Salviae Miltiorrhizae 3g, Cortex Magnoliae Officinalis 4g, Halenia elliptica D. Don 3g, Herba Taraxaci 4g, Fructus Gardeniae 4g, Radix ceratostigmatis willemottiani 3g, Fructus Liquidambaris 4g, wild Semen Canavaliae 6g, Rhizoma Polygonati 8g, Radix Adenophorae (Radix Glehniae) 8g, Radix Ophiopogonis 6g, Fructus Lycii 8g, Radix Paeoniae Alba 6g, breaking cellular wall Pollen Pini 6g.
Preparation method is: mix after above-mentioned medical material is removed impurity respectively, sends in drying baker and dries at 120 DEG C of temperature, be ground into 100-130 order smalls, incapsulate, be finished product after disinfection by ultraviolet light by 0.5g/ grain.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, take 1 course for the treatment of continuously.
Clinical data:
1, case selection:
Select the routine clinical observation of severe acute pancreatitis 37 in my institute's diagnosis and treatment, clinical symptoms all meets Severe Acute Pancreatitis SAP diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 22 example, matched group 15 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; It within 10 days, is 1 course for the treatment of.
Matched group adopts conventional western medicine Comprehensive Treatment, the course for the treatment of same treatment group.
1 course for the treatment of is treated in continuous smelting, contrasts two groups of curative effects.
3, efficacy determination:
(1) be almost recovered: in 10 days, symptom, sign disappear; Blood, amylase in urine drop to normally; Peripheral blood leucocyte, blood glucose, blood calcium are normal; B ultrasonic show pancreas normal, without seroperitoneum.
(2) take a turn for the better: in 10 days, symptom, sign alleviate; Blood, amylase in urine decline; B ultrasonic shows that pancreas edema does not increase the weight of, and seroperitoneum reduces.
(3) do not heal: in 10 days, symptom, sign do not alleviate or worsen; Blood, amylase in urine do not reduce; ; B ultrasonic shows that pancreas edema increases the weight of, cyst, and seroperitoneum increases.
4, result:
Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, be almost recovered 7 examples, and take a turn for the better 13 examples, and do not heal 2 examples, and be almost recovered rate 31.8%, total effective rate 90.9%.
Be almost recovered in matched group 2 examples, and take a turn for the better 9 examples, and do not heal 4 examples, and be almost recovered rate 13.3%, total effective rate 73.3%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.Relevant Chinese medicine and pharmacology thereof all can be obtained by existing open source literature and network, also can with the substitute in the medical material generation of close effect.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (1)
1. one kind is used for the treatment of the Chinese medicinal capsule of Severe Acute Pancreatitis SAP, it is characterized in that, be prepared from by the Chinese crude drug of following weight proportion: Radix Et Rhizoma Rhei 9 parts, 5 parts, Natrii Sulfas, Fructus Aurantii Immaturus 6 parts, wild Fructus Kaki 6 parts, wild Fructus Cumini Cymini 3 parts, pulmonis Bovis seu Bubali 3 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Folium Ilicis Purpureae 3 parts, Herba Sedi Aizoon 4 parts, Radix Aconiti Lateralis Preparata 4 parts, Sapium baccatum Roxb 5 parts, ferreous mesua spends 4 parts, Semen Glycines 12 parts, 3 parts, Radix Glycyrrhizae, Caulis Akebiae 4 parts, Radix Salviae Miltiorrhizae 3 parts, Cortex Magnoliae Officinalis 4 parts, Halenia elliptica D. Don 3 parts, Herba Taraxaci 4 parts, Fructus Gardeniae 4 parts, Radix ceratostigmatis willemottiani 3 parts, Fructus Liquidambaris 4 parts, wild Semen Canavaliae 6 parts, Rhizoma Polygonati 8 parts, Radix Adenophorae (Radix Glehniae) 8 parts, Radix Ophiopogonis 6 parts, Fructus Lycii 8 parts, the Radix Paeoniae Alba 6 parts, breaking cellular wall Pollen Pini 6 parts.
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| CN (1) | CN104984049A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074800A (en) * | 2016-07-15 | 2016-11-09 | 陶健 | The application in terms for the treatment of Severe Acute Pancreatitis SAP of the DACHENGQI TANG associating TDP therapeutic instrument |
| CN106728618A (en) * | 2017-03-01 | 2017-05-31 | 李德军 | A kind of Chinese medicine for treating Severe Acute Pancreatitis SAP |
-
2015
- 2015-06-30 CN CN201510371094.8A patent/CN104984049A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 齐清会等: ""重型胰腺炎84例治疗分析"", 《中国中西医结合杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074800A (en) * | 2016-07-15 | 2016-11-09 | 陶健 | The application in terms for the treatment of Severe Acute Pancreatitis SAP of the DACHENGQI TANG associating TDP therapeutic instrument |
| CN106728618A (en) * | 2017-03-01 | 2017-05-31 | 李德军 | A kind of Chinese medicine for treating Severe Acute Pancreatitis SAP |
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